Substance profile
Coumaphos
Coumaphos is colorless crystals with a slight sulfur-like odor.
01 · Identification
What Coumaphos is
Coumaphos is colorless crystals with a slight sulfur-like odor. Its molecular formula is C14H16ClO5PS and its molecular weight is 362.8 g/mol. It melts at 95.2 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Coumaphos identifiers and molecular data
Coumaphos CAS number and EC number
Coumaphos molecular formula and molecular weight
Other names for Coumaphos
- coumaphos (ISO)
- O-3-chloro-4-methylcoumarin-7-yl O,O-diethyl phosphorothioate
03 · GHS classification
Coumaphos hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Coumaphos pictograms and signal word
Coumaphos hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Coumaphos hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H300 | Fatal if swallowed. |
| H312 | Harmful in contact with skin. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Coumaphos. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Coumaphos
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Coumaphos issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Coumaphos precautionary statements
CLP Annex VI assigns 11 precautionary statements to Coumaphos. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Coumaphos name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | кумафос (ISO) O -4-метил-3-хлорокумарин-7-илов О , О -диетилов фосфоротиоат |
| Spanish español | Cumafós (ISO) fosforotioato de O -3-cloro-4-metilcumarin-7-ilo y O, O -dietilo |
| Czech čeština | kumafos (ISO) O -(3-chlor-4-methyl-2-oxo-2 H -chromen-7-yl)- O, O -diethyl-fosforothioát |
| Danish dansk | coumaphos (ISO) O- 3-chlor-4-methylcumarin-7-yl- O, O- diethylthiophosphat |
| German Deutsch | Coumaphos (ISO) O -3-Chlor-4-methylcumarin-7-yl- O , O -diethylphosphorothioat |
| Estonian eesti | kumafoss (ISO) O -3-kloro-4-metüülkumariin-7-üül- O , O -dietüülfosforotioaat |
| Greek ελληνικά | coumaphos (κουμαφός) (ISO) θειοφωσφορικό O -3-χλωρο-4-μεθυλοκουμαριν-7-ύλιο O , O -διαιθύλιο |
| English English | coumaphos (ISO) O -3-chloro-4-methylcoumarin-7-yl O , O -diethyl phosphorothioate |
| French français | coumaphos (ISO) phosphorothioate de O -3-chloro-4-méthylcoumarin-7-yle et de O, O -diéthyle |
| Croatian hrvatski | kumafos (ISO) O -3-klor-4-metil-kumarin-7-il- O , O -dietil-fosforotioat |
| Italian italiano | cumafos (ISO) tiofosfato di O-3-cloro-4-metilcumarin-7-ile e O, O-dietile |
| Latvian latviešu | kumafoss (ISO) O -3-hlor-4-metilkumarīn-7-il- O , O -dietilfosfortioāts |
| Lithuanian lietuvių | kumachloras (ISO) O -3-chlor-4-metilkumarin-7-il- O , O -dietiltiofosfatas |
| Hungarian magyar | kumafosz (ISO) O -3-klór-4-metilkumarin-7-il O , O -dietil-tiofoszfát |
| Maltese Malti | koumafos (ISO) fosforotijoat ta’ O -3-kloro-4-metilkoumarin-7- il O , O -dietil |
| Dutch Nederlands | cumafos (ISO) O -3-chloor-4-methylcumarine-7-yl- O , O -diëthylthiofosfaat |
| Polish polski | kumafos (ISO) tiofosforan O -3-chloro-4-metylo-2-okso-2 H -chromen-7-ylu- O , O -dietylu |
| Portuguese português | cumafos (ISO) tiofosfato de O -3-cloro-4-metil-7-cumarinilo e de O , O -dietilo |
| Romanian română | cumafos (ISO) tiofosfat de O -3-cloro-4- metilcumarin-7-il și de O , O -dietil |
| Slovak slovenčina | kumafos (ISO) O -(3-chlór-4-metyl-2-oxo-2 H -chromén-7- yl)- O, O -dietyl-fosforotioát |
| Slovenian slovenščina | kumafos (ISO) O -3-kloro-4-metilkumarin-7-il O , O -dietil fosforotioat |
| Finnish suomi | kumafossi (ISO) O -3-kloori-4-metyylikumarin-7-yyli- O , O -dietyylifosforotioaatti |
| Swedish svenska | kumafos (ISO) O -3-klor-4-metylkumarin-7-yl- O , O -dietylfosfortioat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Coumaphos GHS label elements
Everything CLP Annex VI fixes for Coumaphos, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Coumaphos
- Fatal if swallowed.
- Harmful in contact with skin.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/… if you feel unwell.
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Coumaphos in the GHS label constructor →
07 · Health hazards
Coumaphos health hazards and exposure limits
Coumaphos hazard summary
The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Coumaphos carcinogenicity classification
Studied by the US National Toxicology Program: TR-096: Bioassay of Coumaphos for Possible Carcinogenicity (CASRN 56-72-4) (1979 )
Cancer Classification: Not Likely to be Carcinogenic to Humans
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Coumaphos properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Coumaphos boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 20 °C (68 °F) | at 1e-07 mmHg (reduced pressure) | CAMEO |
Coumaphos melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 95.2 °C (203.4 °F) | HSDB | |
| 91.11 °C (196 °F) | CAMEO | ||
| 91 °C (195.8 °F) | ICSC |
Coumaphos density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.474 g/cm³ | HSDB | |
| 1.47 g/cm³ | ICSC | ||
| 1.31 g/cm³ | at 25 °C | CAMEO |
Coumaphos solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Limited solubility in organic solvents | HSDB | |
| Somewhat soluble in acetone, chloroform, corn oil | HSDB | ||
| In water, 1.5 mg/L at 20 °C | at 20 °C | HSDB |
Coumaphos vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 97.508 mmHg | at 20 °C | HSDB |
| 1e-7 mmHg | at 20 °C | CAMEO | |
| 9.7e-8 mmHg | at 20 °C | DOE PAC |
Coumaphos flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | Not Applicable. Combustible solid. (USCG, 1999) | CAMEO |
Coumaphos odor threshold
| Property | Value | Conditions | Source |
|---|---|---|---|
| Odor threshold | 2.0X10-2 ppm (Detection in water; purity not specified). | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Coumaphos fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Coumaphos fire potential
It is combustible ...
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Coumaphos storage and handling
Coumaphos safe storage
Separated from food and feedstuffs. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Coumaphos storage conditions
Storage temperature: Ambient
Source: Hazardous Substances Data Bank (HSDB)
Coumaphos incompatible materials
Strong oxidizing agents
Source: Hazardous Substances Data Bank (HSDB)
Coumaphos reactivity
Organothiophosphates, such as COUMAPHOS, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. It reacts with strong oxidizing agents and alkaline materials. (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Coumaphos in the storage compatibility matrix →
11 · Questions
Coumaphos — frequently asked questions
What is the CAS number of Coumaphos?
The CAS number of Coumaphos is 56-72-4. Its EC number is 200-285-3.
What is the chemical formula of Coumaphos?
The molecular formula of Coumaphos is C14H16ClO5PS and its molecular weight is 362.8 g/mol.
What does a Coumaphos label have to show?
Under CLP Annex VI the label for Coumaphos carries the pictograms Skull and crossbones and Environment and the signal word is Danger.
Is Coumaphos flammable?
CLP Annex VI assigns Coumaphos no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is Not Applicable. Combustible solid. (USCG, 1999) (CAMEO).
Is Coumaphos a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Coumaphos. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Coumaphos?
The boiling point reported for Coumaphos is 20 °C (68 °F), at 1e-07 mmHg (reduced pressure) (CAMEO).
What is the melting point of Coumaphos?
The melting point reported for Coumaphos is 95.2 °C (203.4 °F) (HSDB).
How should Coumaphos be stored?
Storage temperature: Ambient (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Coumaphos
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