Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Diethylamine

Diethylamine is a colorless liquid with a fishy, ammonia-like odor.

CAS 109-89-7 C4H11N 73.14 g/mol Danger

01 · Identification

What Diethylamine is

Diethylamine is a colorless liquid with a fishy, ammonia-like odor. Its molecular formula is C4H11N and its molecular weight is 73.14 g/mol. It boils at 55.5 °C, melts at -50 °C.

Under the GHS it carries the signal word Danger. It is classed as corrosives.

02 · Identifiers

Diethylamine identifiers and molecular data

Diethylamine CAS number and EC number

CAS number109-89-7
EC number203-716-3
Index number (CLP Annex VI)612-003-00-X

Diethylamine molecular formula and molecular weight

Molecular formulaC4H11N
Molecular weight73.14 g/mol
Chemical class Corrosives

03 · GHS classification

Diethylamine hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Diethylamine pictograms and signal word

Signal wordDanger

Diethylamine hazard class and category

GHS hazard classes Diethylamine falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 2 H225 GHS02
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Acute toxicity - dermal GHS chapter 3.1 Category 4 H312 GHS07
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07
Skin corrosion/irritation GHS chapter 3.2 Category 1A or 1B or 1C H314 GHS05

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Diethylamine hazard statements (H-codes)

Hazard statements assigned to Diethylamine
CodeHazard statement
H225 Highly flammable liquid and vapour.
H332 Harmful if inhaled.
H312 Harmful in contact with skin.
H302 Harmful if swallowed.
H314 Causes severe skin burns and eye damage.

This page lists only the codes assigned to Diethylamine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Diethylamine

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Diethylamine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Diethylamine precautionary statements

CLP Annex VI assigns 17 precautionary statements to Diethylamine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Diethylamine name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български диетиламин
Spanish español Dietilamina
Czech čeština diethylamin
Danish dansk diethylamin
German Deutsch Diethylamin
Estonian eesti dietüülamiin
Greek ελληνικά διαιθυλαμίνη
English English diethylamine
French français diéthylamine
Croatian hrvatski dietilamin
Italian italiano dietilamina
Latvian latviešu dietilamīns
Lithuanian lietuvių dietilaminas
Hungarian magyar dietilamin
Maltese Malti karbonat tad-diċikloessilmetil (INNCN)
Dutch Nederlands diëthylamine
Polish polski dietyloamina
Portuguese português dietilamina
Romanian română dietilamină
Slovak slovenčina dietylamín
Slovenian slovenščina dietilamin
Finnish suomi dietyyliamiini
Swedish svenska dietylamin

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Diethylamine GHS label elements

Everything CLP Annex VI fixes for Diethylamine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS05 Corrosion pictogramGHS07 Exclamation mark pictogram

Danger

Diethylamine

  • Highly flammable liquid and vapour.
  • Harmful if inhaled.
  • Harmful in contact with skin.
  • Harmful if swallowed.
  • Causes severe skin burns and eye damage.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF INHALED:
  • Immediately call a POISON CENTER/doctor/
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Rinse mouth.
  • Do NOT induce vomiting.
  • Wash with plenty of water/
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Diethylamine in the GHS label constructor →

07 · Health hazards

Diethylamine health hazards and exposure limits

Diethylamine hazard summary

Diethylamine can cause necrosis to the skin. Rabbits exposed to 100 ppm, 7 hours/day, 5 days/week for 6 weeks have bronchopneumonia; [ACGIH] If left on clothing, can cause reddening of skin; [CHRIS] Corrosive to skin; [Quick CPC] Causes liver damage in high-dose animal studies; [HSDB] A corrosive substance that can cause pulmonary edema; [ICSC]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Diethylamine carcinogenicity classification

Under the conditions of these 2-year inhalation studies, there was no evidence of carcinogenic activity of diethylamine in male or female F344/N rats exposed to 31, 62.5, or 125 ppm. There was no evidence of carcinogenic activity of diethylamine in male or female B6C3F1 mice exposed to 16, 31, or 62.5 ppm.

Source: US National Toxicology Program · TR-566: Toxicology and Carcinogenesis Studies of Diethylamine (CASRN 109-89-7) in F344/N Rats and B6C3F1 Mice (Inhalation studies) (2011 )

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

Diethylamine occupational exposure limits

US occupational exposure limits reported for Diethylamine. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 25.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
PEL 25 ppm (75 mg/m³) Occupational Safety and Health Administration (OSHA)
PEL TWA 25 ppm (75 mg/m3) See Appendix G The National Institute for Occupational Safety and Health (NIOSH)
REL 10 ppm (30 mg/m³) Occupational Safety and Health Administration (OSHA)
REL 25 ppm (75 mg/m³) Occupational Safety and Health Administration (OSHA)
REL TWA 10 ppm (30 mg/m3) ST 25 ppm (75 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
IDLH 200 ppm (NIOSH, 2024) CAMEO Chemicals
IDLH 200.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
IDLH 200 ppm Hazardous Substances Data Bank (HSDB)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Diethylamine properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Diethylamine boiling point

Property Value Conditions Source
Boiling point 55.5 °C (131.9 °F) HSDB
55.56 °C (132 °F) NIOSH
55.5 °C (131.9 °F) at 760 mmHg CAMEO

Diethylamine melting point

Property Value Conditions Source
Melting point -50 °C (-58 °F) HSDB

Diethylamine density

Property Value Conditions Source
Density 0.246 g/cm³ HSDB
0.71 g/cm³ NIOSH
0.7056 g/cm³ at 20 °C HSDB

Diethylamine solubility

Property Value Conditions Source
Solubility Miscible with water, alcohol HSDB
Soluble in ether and carbon tetrachloride HSDB
In water, infinitely soluble /1X10+6 mg/L/ at 25 °C at 25 °C HSDB

Diethylamine vapor pressure

Property Value Conditions Source
Vapor pressure 192 mmHg NIOSH
195 mmHg at 20 °C CAMEO
237 mmHg at 25 °C HSDB

Diethylamine flash point

Property Value Conditions Source
Flash point -22.99 °C (-9.4 °F) HSDB
-15 °C (5 °F) HSDB
17.8 °C (64 °F) HSDB

Diethylamine autoignition temperature

Property Value Conditions Source
Autoignition temperature 312.22 °C (594 °F) HSDB
312 °C (593.6 °F) ICSC

Diethylamine lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 1.8 % by volume HSDB

Diethylamine upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 10.1 % by volume HSDB

Diethylamine vapor density

Property Value Conditions Source
Vapor density 2.52 (air = 1) HSDB
2.53 (air = 1) CAMEO
2.5 (air = 1) ICSC

Diethylamine odor threshold

Property Value Conditions Source
Odor threshold Odor detection in air= 2.0X10-2 ppm (Purity not specified) HSDB
Odor recognition in air= 6.0X10-2 ppm (Purity not specified) HSDB
Odor detection in water= 1.21X10+1 ppm (Chemically pure) HSDB

Diethylamine critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 226.35 °C (439.4 °F) HSDB

Diethylamine corrosivity

Property Value Conditions Source
Corrosivity Liquid diethylamine will attack some forms of plastics, rubber, and coatings. HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Diethylamine fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Diethylamine fire potential

A very dangerous fire hazard when exposed to heat, flame, or oxidizers.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Diethylamine storage and handling

Diethylamine safe storage

Fireproof. Separated from strong oxidizers, strong acids, organic compounds and food and feedstuffs. Cool. Well closed. Store only in original container. Store in an area without drain or sewer access.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Diethylamine storage conditions

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Flammable liquids.

Source: Hazardous Substances Data Bank (HSDB)

Diethylamine incompatible materials

Incompatible materials: Aldehydes, alcohols, dicyanofurazan, ketones, phenols, acids, halogenated hydrocarbon, oxidizing agents, epoxides.

Source: Hazardous Substances Data Bank (HSDB)

Diethylamine reactivity

DIETHYLAMINE is strongly alkaline. Incompatible with strong oxidizing agents and with strong acids. Violent reactions occur with sulfuric acid. Causes ignition on contact with cellulose nitrate. Explodes on contact with dicyanofurazan or dicyanofuroxan. Attacks some forms of plastics, rubber and coatings. (NTP, 1992)

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Diethylamine in the storage compatibility matrix →

11 · Transport

Diethylamine UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Diethylamine under UN 1154 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
DIETHYLAMINE 3 FC II
  • ADR label model 3 — Flammable liquid
  • ADR label model 8 — Corrosive substance
3, 8

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 3 is “Flammable liquids” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Diethylamine 3 II
  • US DOT FLAMMABLE LIQUID label (§172.419)
  • US DOT CORROSIVE label (§172.442)
3, 8

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 3 is “Flammable and combustible liquid” (49 CFR 173.2).

Full UN 1154 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

Diethylamine — frequently asked questions

What is the CAS number of Diethylamine?

The CAS number of Diethylamine is 109-89-7. Its EC number is 203-716-3.

What is the chemical formula of Diethylamine?

The molecular formula of Diethylamine is C4H11N and its molecular weight is 73.14 g/mol.

What does a Diethylamine label have to show?

Under CLP Annex VI the label for Diethylamine carries the pictograms Flame, Corrosion and Exclamation mark and the signal word is Danger.

Is Diethylamine flammable?

Yes. CLP Annex VI assigns Diethylamine H225 — highly flammable liquid and vapour. The flash point reported for it is -22.99 °C (-9.4 °F) (HSDB).

Is Diethylamine a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Diethylamine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Diethylamine?

The US occupational exposure limit reported for Diethylamine is 25.0 [ppm] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Diethylamine?

The boiling point reported for Diethylamine is 55.5 °C (131.9 °F) (HSDB).

What is the melting point of Diethylamine?

The melting point reported for Diethylamine is -50 °C (-58 °F) (HSDB).

How should Diethylamine be stored?

CLP Annex VI assigns Diethylamine the storage statement P403. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Flammable liquids. (Hazardous Substances Data Bank (HSDB))

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