Substance profile
2-isopropoxyethanol
2-isopropoxyethanol is a colorless liquid with a mild ethereal odor.
01 · Identification
What 2-isopropoxyethanol is
2-isopropoxyethanol is a colorless liquid with a mild ethereal odor. Its molecular formula is C5H12O2 and its molecular weight is 104.15 g/mol. It boils at 144 °C, melts at -60 °C.
Under the GHS it carries the signal word Warning. It is classed as flammable agents - 2nd degree.
02 · Identifiers
2-isopropoxyethanol identifiers and molecular data
2-isopropoxyethanol CAS number and EC number
2-isopropoxyethanol molecular formula and molecular weight
Other names for 2-isopropoxyethanol
- ethylene glycol monoisopropyl ether
03 · GHS classification
2-isopropoxyethanol hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
2-isopropoxyethanol pictograms and signal word
2-isopropoxyethanol hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 4 | H332 | GHS07 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
2-isopropoxyethanol hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H332 | Harmful if inhaled. |
| H312 | Harmful in contact with skin. |
| H319 | Causes serious eye irritation. |
This page lists only the codes assigned to 2-isopropoxyethanol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 2-isopropoxyethanol
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2-isopropoxyethanol issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
2-isopropoxyethanol precautionary statements
CLP Annex VI assigns 12 precautionary statements to 2-isopropoxyethanol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
2-isopropoxyethanol name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 2-изопропоксиетанол моноизопропилов етер на етиленгликола |
| Spanish español | 2-Isopropoxietanol éter monoisopropílico de etilenglicol |
| Czech čeština | 2-isopropoxyethan-1-ol isopropylglykol |
| Danish dansk | 2-isopropoxyethanol isopropylglycol |
| German Deutsch | 2-Isopropoxyethanol IsopropylglycolEthylenglykol-monoisopropylether |
| Estonian eesti | 2-isopropoksüetanool etüleenglükooli monoisopropüüleeter |
| Greek ελληνικά | 2-ισοπροποξυαιθανόλη μονοϊσοπροπυλαιθέρας της αιθυλενογλυκόλης |
| English English | 2-isopropoxyethanol ethylene glycol monoisopropyl ether |
| French français | 2-isopropoxyéthanol éther monoisopropylique d'éthylène glycol |
| Croatian hrvatski | 2-izopropoksietanol etilen-glikol-monoizopropil-eter |
| Italian italiano | 2-isopropossietanolo etilenglicol-monoisopropiletere isopropilglicol |
| Latvian latviešu | 2-izopropoksietanols etiletilēnglikola monoizopropiletilēteris |
| Lithuanian lietuvių | 2-izopropoksietanolis etilenglikolio monoizopropileteris |
| Hungarian magyar | 2-izopropoxietanol etilén-glikol-monoizopropil-éter |
| Maltese Malti | 2-isopropossietanol eter tal-monoisopropil tal-glikol tal-etilen |
| Dutch Nederlands | 2-isopropoxyethanol ethyleenglycolmonoïsopropylether |
| Polish polski | 2-izopropoksyetanol eter monoizopropylowy glikolu etylenowegocellosolw izopropylowy |
| Portuguese português | 2-isopropoxietanol éter monoisopropílico de etilenoglicol |
| Romanian română | 2-isopropoxietanol eter monoizopropilic al etilenglicolului |
| Slovak slovenčina | 2-izopropoxyetanol etylénglykol-monoizopropyléter |
| Slovenian slovenščina | 2-izopropoksietanol etilenglikol monoizopropil eter |
| Finnish suomi | 2-isopropoksietanoli etyleeniglykolimonoisopropyylieetteri |
| Swedish svenska | 2-isopropoxietanol etylenglykolmonoisopropyleter |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
2-isopropoxyethanol GHS label elements
Everything CLP Annex VI fixes for 2-isopropoxyethanol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
2-isopropoxyethanol
- Harmful if inhaled.
- Harmful in contact with skin.
- Causes serious eye irritation.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Use only outdoors or in a well-ventilated area.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF ON SKIN:
- IF INHALED:
- IF IN EYES:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 2-isopropoxyethanol in the GHS label constructor →
07 · Health hazards
2-isopropoxyethanol health hazards and exposure limits
2-isopropoxyethanol hazard summary
Osmotic fragility of rat erythrocytes markedly increased at exposures of 200 ppm; [ACGIH] Inhalation of high concentrations can cause CNS depression; [HSDB] May cause skin and eye irritation; [CAMEO] See Glycol ethers.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
2-isopropoxyethanol occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | none See Appendix G | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | N.D. | The National Institute for Occupational Safety and Health (NIOSH) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
2-isopropoxyethanol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
2-isopropoxyethanol boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 144 °C (291.2 °F) | at 743 mmHg | HSDB |
| 139.44 °C (283 °F) | NIOSH | ||
| 141 °C (285.8 °F) | at 760 mmHg | CAMEO |
2-isopropoxyethanol melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -60 °C (-76 °F) | ICSC |
2-isopropoxyethanol density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 0.9 g/cm³ | NIOSH | |
| 0.91 g/cm³ | CAMEO | ||
| 0.903 g/cm³ | at 20 °C | HSDB |
2-isopropoxyethanol solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | SOL IN ALL PROP IN WATER, ALC, ETHER; SOL IN ACETONE | HSDB | |
| Miscible | NIOSH | ||
| Miscible (NIOSH, 2024) | CAMEO |
2-isopropoxyethanol vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 3 mmHg | NIOSH | |
| 5.2 mmHg | at 25 °C | HSDB |
2-isopropoxyethanol flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 33.33 °C (92 °F) | HSDB | |
| 33 °C (91.4 °F) | CAMEO |
2-isopropoxyethanol autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 240 °C (464 °F) | ICSC |
2-isopropoxyethanol lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 1.6 % by volume | ICSC | |
| Class IC Flammable Liquid: Fl.P. at or above 73 °F and below 100 °F. | NIOSH |
2-isopropoxyethanol upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 13 % by volume | ICSC |
2-isopropoxyethanol vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 3.6 (air = 1) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
2-isopropoxyethanol fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
2-isopropoxyethanol fire potential
MODERATE; CAN REACT WITH OXIDIZING MATERIALS
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
2-isopropoxyethanol storage and handling
2-isopropoxyethanol safe storage
Cool. Fireproof. Separated from strong oxidants.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
2-isopropoxyethanol storage conditions
SEE ETHERS. ETHERS SHOULD NOT BE STORED NEAR POWERFUL OXIDIZERS OR IN AREAS OF HIGH FIRE HAZARD. THEY SHOULD BE KEPT COOL AND THE CONTAINERS ELECTRICALLY GROUNDED TO AVOID SPARKS. /ETHERS/
Source: Hazardous Substances Data Bank (HSDB)
2-isopropoxyethanol incompatible materials
Oxidizers.
Source: Hazardous Substances Data Bank (HSDB)
2-isopropoxyethanol reactivity
ETHYLENE GLYCOL ISOPROPYL ETHER acts both as an alcohol and ether. May react violently with strong oxidizing agents. May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. May initiate the polymerization of isocyanates and epoxides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 2-isopropoxyethanol in the storage compatibility matrix →
11 · Questions
2-isopropoxyethanol — frequently asked questions
What is the CAS number of 2-isopropoxyethanol?
The CAS number of 2-isopropoxyethanol is 109-59-1. Its EC number is 203-685-6.
What is the chemical formula of 2-isopropoxyethanol?
The molecular formula of 2-isopropoxyethanol is C5H12O2 and its molecular weight is 104.15 g/mol.
What does a 2-isopropoxyethanol label have to show?
Under CLP Annex VI the label for 2-isopropoxyethanol carries the pictogram Exclamation mark and the signal word is Warning.
Is 2-isopropoxyethanol flammable?
CLP Annex VI assigns 2-isopropoxyethanol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 33.33 °C (92 °F) (HSDB).
Is 2-isopropoxyethanol a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 2-isopropoxyethanol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the exposure limit for 2-isopropoxyethanol?
The US occupational exposure limit reported for 2-isopropoxyethanol is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of 2-isopropoxyethanol?
The boiling point reported for 2-isopropoxyethanol is 144 °C (291.2 °F), at 743 mmHg (HSDB).
What is the melting point of 2-isopropoxyethanol?
The melting point reported for 2-isopropoxyethanol is -60 °C (-76 °F) (ICSC).
How should 2-isopropoxyethanol be stored?
SEE ETHERS. ETHERS SHOULD NOT BE STORED NEAR POWERFUL OXIDIZERS OR IN AREAS OF HIGH FIRE HAZARD. THEY SHOULD BE KEPT COOL AND THE CONTAINERS ELECTRICALLY GROUNDED TO AVOID SPARKS. /ETHERS/ (Hazardous Substances Data Bank (HSDB))
Nearby
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