Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Cyclohexylamine

Cyclohexylamine is a colorless or yellow liquid with a strong, fishy, amine odor.

CAS 108-91-8 Danger

01 · Identification

What Cyclohexylamine is

Cyclohexylamine is a colorless or yellow liquid with a strong, fishy, amine odor. It boils at 135 °C, melts at -17.7 °C, is very soluble in water.

Under the GHS it carries the signal word Danger. It is classed as corrosives.

02 · Identifiers

Cyclohexylamine identifiers and molecular data

Cyclohexylamine CAS number and EC number

CAS number108-91-8
EC number203-629-0
Index number (CLP Annex VI)612-050-00-6

Cyclohexylamine molecular formula and molecular weight

Chemical class Corrosives

03 · GHS classification

Cyclohexylamine hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Cyclohexylamine pictograms and signal word

Signal wordDanger

Cyclohexylamine hazard class and category

GHS hazard classes Cyclohexylamine falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 3 H226 GHS02
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Acute toxicity - dermal GHS chapter 3.1 Category 4 H312 GHS07
Skin corrosion/irritation GHS chapter 3.2 Category 1A or 1B or 1C H314 GHS05

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Cyclohexylamine hazard statements (H-codes)

Hazard statements assigned to Cyclohexylamine
CodeHazard statement
H226 Flammable liquid and vapour.
H361f Suspected of damaging fertility.
H312 Harmful in contact with skin.
H302 Harmful if swallowed.
H314 Causes severe skin burns and eye damage.

This page lists only the codes assigned to Cyclohexylamine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Cyclohexylamine

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Cyclohexylamine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Cyclohexylamine precautionary statements

CLP Annex VI assigns 15 precautionary statements to Cyclohexylamine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Cyclohexylamine name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български циклохексиламин
Spanish español Ciclohexilamina
Czech čeština cyklohexylamin
Danish dansk cyclohexylamin
German Deutsch Cyclohexylamin
Estonian eesti tsükloheksüülamiin
Greek ελληνικά κυκλοεξυλαμίνη
English English cyclohexylamine
French français cyclohexylamine
Croatian hrvatski cikloheksilamin
Italian italiano cicloesilammina
Latvian latviešu cikloheksilamīns
Lithuanian lietuvių cikloheksilaminas
Hungarian magyar ciklohexilamin
Maltese Malti ċikloessilammina
Dutch Nederlands cyclohexylamine
Polish polski cykloheksyloamina CHA
Portuguese português ciclo-hexilamina
Romanian română ciclohexilamină
Slovak slovenčina cyklohexylamín cyklohexánamín
Slovenian slovenščina cikloheksilamin
Finnish suomi sykloheksyyliamiini
Swedish svenska cyklohexylamin

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Cyclohexylamine GHS label elements

Everything CLP Annex VI fixes for Cyclohexylamine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS05 Corrosion pictogramGHS08 Health hazard pictogramGHS07 Exclamation mark pictogram

Danger

Cyclohexylamine

  • Flammable liquid and vapour.
  • Suspected of damaging fertility.
  • Harmful in contact with skin.
  • Harmful if swallowed.
  • Causes severe skin burns and eye damage.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • Immediately call a POISON CENTER/doctor/
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Rinse mouth.
  • Do NOT induce vomiting.
  • Wash with plenty of water/
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Cyclohexylamine in the GHS label constructor →

07 · Health hazards

Cyclohexylamine health hazards and exposure limits

Cyclohexylamine hazard summary

Cyclohexylamine has moderate skin sensitizing potential and is a weak methemoglobin inducer. Listed in the table Examples of Industrial Chemicals for Which Methemoglobin Formation is NOT the Principal Cause of Toxicity; [ACGIH] Merck Index # 2729; Causes second and third degree burns after short skin exposure; [CHRIS] Corrosive to skin; [Quick CPC] Corrosive to the skin, eyes, and respiratory tract; Inhalation of high concentrations may cause CNS effects; [ICSC] No apparent effects in workers exposed to 4-10 ppm; Inhalation of high concentrations could cause pulmonary edema; A 25% solution produced severe irritation of the skin in humans; May cause permanent eye injury; Transient visual effects (blue haze or halo vision) occur at low concentrations; [CHEMINFO]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Cyclohexylamine occupational exposure limits

US occupational exposure limits reported for Cyclohexylamine. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL none See Appendix G The National Institute for Occupational Safety and Health (NIOSH)
REL 10 ppm (40 mg/m³) Occupational Safety and Health Administration (OSHA)
REL TWA 10 ppm (40 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
IDLH N.D. The National Institute for Occupational Safety and Health (NIOSH)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Cyclohexylamine properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Cyclohexylamine boiling point

Property Value Conditions Source
Boiling point 134.5 °C (274.1 °F) at 760 mmHg HSDB
134.44 °C (274 °F) NIOSH

Cyclohexylamine melting point

Property Value Conditions Source
Melting point -17.7 °C (0.1 °F) HSDB
-17.78 °C (0 °F) NIOSH
-17.72 °C (0.1 °F) CAMEO

Cyclohexylamine density

Property Value Conditions Source
Density 0.87 g/cm³ NIOSH
0.8647 g/cm³ at 25 °C HSDB

Cyclohexylamine solubility

Property Value Conditions Source
Solubility Very soluble in ethanol, miscible in ether and acetone. HSDB
Miscible with common organic solvents: alcohol, ethers, ketones, esters, aliphatic hydrocarbons; completely miscible with aromatic hydrocarbons. HSDB
SOL IN CHLORINATED HYDROCARBONS, MINERAL OIL, PEANUT OIL AND SOYA BEAN OIL HSDB

Cyclohexylamine vapor pressure

Property Value Conditions Source
Vapor pressure 11 mmHg NIOSH
10.1 mmHg at 25 °C HSDB

Cyclohexylamine flash point

Property Value Conditions Source
Flash point 31.11 °C (88 °F) HSDB

Cyclohexylamine autoignition temperature

Property Value Conditions Source
Autoignition temperature 293.33 °C (560 °F) HSDB
293 °C (559.4 °F) ICSC

Cyclohexylamine lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 1.5 % by volume NIOSH

Cyclohexylamine upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 9.4 % by volume NIOSH

Cyclohexylamine vapor density

Property Value Conditions Source
Vapor density 3.42 (air = 1) HSDB

Cyclohexylamine odor threshold

Property Value Conditions Source
Odor threshold Odor Threshold Low: 2.6 [ppm] Haz-Map
Odor Threshold High: 110.0 [ppm] Haz-Map
Odor thresholds from CHEMINFO Haz-Map

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Cyclohexylamine fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Cyclohexylamine fire potential

FLAMMABLE LIQUID...

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Cyclohexylamine storage and handling

Cyclohexylamine safe storage

Fireproof. Separated from acids, oxidants, aluminium, copper, zinc and food and feedstuffs. Well closed.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Cyclohexylamine storage conditions

Outside or detached storage is preferred. Avoid oxidizing materials, acid, and sources of halogen. Store in a cool, dry well-ventilated location.

Source: Hazardous Substances Data Bank (HSDB)

Cyclohexylamine incompatible materials

Oxidizers, organic compounds, acid anhydrides, acid chlorides, acids, lead [Note: Corrosive to copper, aluminum, zinc & galvanized steel].

Source: Hazardous Substances Data Bank (HSDB)

Cyclohexylamine reactivity

CYCLOHEXYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Cyclohexylamine in the storage compatibility matrix →

11 · Transport

Cyclohexylamine UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Cyclohexylamine under UN 2357 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
CYCLOHEXYLAMINE 8 CF1 II
  • ADR label model 8 — Corrosive substance
  • ADR label model 3 — Flammable liquid
8, 3

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 8 is “Corrosive substances” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Cyclohexylamine 8 II
  • US DOT CORROSIVE label (§172.442)
  • US DOT FLAMMABLE LIQUID label (§172.419)
8, 3

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 8 is “Corrosive material” (49 CFR 173.2).

Full UN 2357 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

Cyclohexylamine — frequently asked questions

What is the CAS number of Cyclohexylamine?

The CAS number of Cyclohexylamine is 108-91-8. Its EC number is 203-629-0.

What does a Cyclohexylamine label have to show?

Under CLP Annex VI the label for Cyclohexylamine carries the pictograms Flame, Corrosion, Health hazard and Exclamation mark and the signal word is Danger.

Is Cyclohexylamine flammable?

Yes. CLP Annex VI assigns Cyclohexylamine H226 — flammable liquid and vapour. The flash point reported for it is 31.11 °C (88 °F) (HSDB).

Is Cyclohexylamine a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Cyclohexylamine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Cyclohexylamine?

The US occupational exposure limit reported for Cyclohexylamine is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Cyclohexylamine?

The boiling point reported for Cyclohexylamine is 134.5 °C (274.1 °F), at 760 mmHg (HSDB).

What is the melting point of Cyclohexylamine?

The melting point reported for Cyclohexylamine is -17.7 °C (0.1 °F) (HSDB).

How should Cyclohexylamine be stored?

CLP Annex VI assigns Cyclohexylamine the storage statement P403. Outside or detached storage is preferred. Avoid oxidizing materials, acid, and sources of halogen. Store in a cool, dry well-ventilated location. (Hazardous Substances Data Bank (HSDB))

Nearby

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