Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Iodine

Iodine is bluish-black scales or plates; diatomic; violet vapor with a sharp characteristic odor.

CAS 7553-56-2 Warning

01 · Identification

What Iodine is

Iodine is bluish-black scales or plates; diatomic; violet vapor with a sharp characteristic odor. It boils at 184 °C, melts at 114 °C.

Under the GHS it carries the signal word Warning.

02 · Identifiers

Iodine identifiers and molecular data

Iodine CAS number and EC number

CAS number7553-56-2
EC number231-442-4
Index number (CLP Annex VI)053-001-00-3

03 · GHS classification

Iodine hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Iodine pictograms and signal word

Signal wordWarning

Iodine hazard class and category

GHS hazard classes Iodine falls into
Hazard class Category From code Pictogram
Acute toxicity - dermal GHS chapter 3.1 Category 4 H312 GHS07
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09

Iodine hazard statements (H-codes)

Hazard statements assigned to Iodine
CodeHazard statement
H332 Harmful if inhaled.
H312 Harmful in contact with skin.
H400 Very toxic to aquatic life.

This page lists only the codes assigned to Iodine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Iodine

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Iodine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Iodine precautionary statements

CLP Annex VI assigns 10 precautionary statements to Iodine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Iodine name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български йод
Spanish español Yodo
Czech čeština jod
Danish dansk iod
German Deutsch Iod
Estonian eesti jood
Greek ελληνικά ιώδιο
English English iodine
French français iode
Croatian hrvatski jod
Italian italiano iodio
Latvian latviešu jodīns
Lithuanian lietuvių jodas
Hungarian magyar jód
Maltese Malti jodju
Dutch Nederlands jood
Polish polski jod
Portuguese português iodo
Romanian română iod
Slovak slovenčina jód
Slovenian slovenščina jod
Finnish suomi jodi
Swedish svenska jod

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Iodine GHS label elements

Everything CLP Annex VI fixes for Iodine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS07 Exclamation mark pictogramGHS09 Environment pictogram

Warning

Iodine

  • Harmful if inhaled.
  • Harmful in contact with skin.
  • Very toxic to aquatic life.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Use only outdoors or in a well-ventilated area.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF ON SKIN:
  • IF INHALED:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Iodine in the GHS label constructor →

07 · Health hazards

Iodine health hazards and exposure limits

Iodine hazard summary

Iodine is a naturally occurring element found in sea water and in certain rocks and sediments. There are non radioactive and radioactive forms of iodine. Iodine is used as a disinfectant for cleaning surfaces and storage containers and is used in skin soaps and bandages, and for purifying water. Iodine is also added to some table salt to ensure that all people in the United States have enough iodine in their diet. Most radioactive iodine is manmade. It is used in medical tests and to treat certain diseases. Most radioactive forms of iodine change very quickly (seconds to days) to stable elements that are not radioactive. However, 129I (read as iodine 129) changes very slowly (over millions of years).

Source: Agency for Toxic Substances and Disease Registry (ATSDR)

Iodine occupational exposure limits

US occupational exposure limits reported for Iodine. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 0.1 ppm (1 mg/m³) Occupational Safety and Health Administration (OSHA)
PEL C 0.1 ppm (1 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
REL 0.1 ppm (1 mg/m³) Occupational Safety and Health Administration (OSHA)
REL C 0.1 ppm (1 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
IDLH 2 ppm (NIOSH, 2024) CAMEO Chemicals
IDLH 2.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
IDLH 2 ppm Hazardous Substances Data Bank (HSDB)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Iodine properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Iodine boiling point

Property Value Conditions Source
Boiling point 184.4 °C (363.9 °F) HSDB
185 °C (365 °F) NIOSH
185 °C (365 °F) at 760 mmHg CAMEO

Iodine melting point

Property Value Conditions Source
Melting point 113.7 °C (236.7 °F) HSDB
113.33 °C (236 °F) NIOSH

Iodine density

Property Value Conditions Source
Density 4.93 g/cm³ NIOSH
0.0113 g/cm³ at 20 °C HSDB

Iodine solubility

Property Value Conditions Source
Solubility Dissolves readily in chloroform, carbon tetrachloride, or carbon disulfide to form purple solns. HSDB
2.719 g in cyclohexane; 23 g/100 cc in methanol at 25 °C; 20.5 g/100 cc in alcohol at 15 °C; 20.6 g/100 cc in ether at 17 °C at 25 °C HSDB

Iodine vapor pressure

Property Value Conditions Source
Vapor pressure 0.233 mmHg at 25 °C HSDB
0.3 mmHg at 25 °C NIOSH

Iodine lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) Noncombustible Solid NIOSH

Iodine vapor density

Property Value Conditions Source
Vapor density 8.8 (air = 1) ICSC
6.75 g/L at 101.3 MPa, 185 °C at 185 °C, at 759813 mmHg HSDB

Iodine odor threshold

Property Value Conditions Source
Odor threshold Odor low= 9.00 mg/cu m; Odor high= 9.00 mg/cu m; Irritating Concn= 2.0 mg/cu m HSDB

Iodine critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 546 °C (1014.8 °F) HSDB

Iodine corrosivity

Property Value Conditions Source
Corrosivity Vapor is corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Iodine storage and handling

Iodine safe storage

Separated from incompatible materials. See Chemical Dangers. Well closed. Ventilation along the floor.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Iodine storage conditions

Materials which are toxic as stored or which can decompose into toxic components ... Should be stored in a cool, well-ventilated place, out of the direct rays of the sun, away from areas of high fire hazard, and should be periodically inspected. Incompatible materials should be isolated ... .

Source: Hazardous Substances Data Bank (HSDB)

Iodine incompatible materials

The reaction between liquid chlorine and iodine is violent.

Source: Hazardous Substances Data Bank (HSDB)

Iodine reactivity

IODINE is an oxidizing agent. Reacts vigorously with reducing materials. Incompatible with powdered metals in the presence of water (ignites), with gaseous or aqueous ammonia (forms explosive products), with acetylene (reacts explosively), with acetaldehyde (violent reaction), with metal azides (forms yellow explosive iodoazides), with metal hydrides (ignites), with metal carbides (ignites easily), with potassium and sodium (forms shock-senstive explosive compounds) and with alkali-earth metals (ignites). Incompatible with ethanol, formamide, chlorine, bromine, bromine trifluoride, chlorine trifluoride.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Iodine in the storage compatibility matrix →

10 · Transport

Iodine UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Iodine under UN 3495 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
IODINE 8 CT2 III
  • ADR label model 8 — Corrosive substance
  • ADR label model 6.1 — Toxic substance
8, 6.1

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 8 is “Corrosive substances” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Iodine 8 III
  • US DOT CORROSIVE label (§172.442)
  • US DOT POISON label (§172.430)
8, 6.1

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 8 is “Corrosive material” (49 CFR 173.2).

Full UN 3495 entry — special provisions, packing instructions, quantity limits and the orange plate →

11 · Questions

Iodine — frequently asked questions

What is the CAS number of Iodine?

The CAS number of Iodine is 7553-56-2. Its EC number is 231-442-4.

What does a Iodine label have to show?

Under CLP Annex VI the label for Iodine carries the pictograms Exclamation mark and Environment and the signal word is Warning.

Is Iodine flammable?

CLP Annex VI assigns Iodine no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Iodine a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Iodine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Iodine?

The US occupational exposure limit reported for Iodine is 0.1 ppm (1 mg/m³) (Occupational Safety and Health Administration (OSHA)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Iodine?

The boiling point reported for Iodine is 184.4 °C (363.9 °F) (HSDB).

What is the melting point of Iodine?

The melting point reported for Iodine is 113.7 °C (236.7 °F) (HSDB).

How should Iodine be stored?

Materials which are toxic as stored or which can decompose into toxic components ... Should be stored in a cool, well-ventilated place, out of the direct rays of the sun, away from areas of high fire hazard, and should be periodically inspected. Incompatible materials should be isolated ... . (Hazardous Substances Data Bank (HSDB))

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