Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Iodoacetic Acid

Iodoacetic Acid is colorless or white crystals.

CAS 64-69-7 C2H3IO2 185.95 g/mol Danger

01 · Identification

What Iodoacetic Acid is

Iodoacetic Acid is colorless or white crystals. Its molecular formula is C2H3IO2 and its molecular weight is 185.95 g/mol. It melts at 210 °C, is soluble in water.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Iodoacetic Acid identifiers and molecular data

Iodoacetic Acid CAS number and EC number

CAS number64-69-7
EC number200-590-1
Index number (CLP Annex VI)607-068-00-6

Iodoacetic Acid molecular formula and molecular weight

Molecular formulaC2H3IO2
Molecular weight185.95 g/mol

03 · GHS classification

Iodoacetic Acid hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Iodoacetic Acid pictograms and signal word

Signal wordDanger

Iodoacetic Acid hazard class and category

GHS hazard classes Iodoacetic Acid falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Skin corrosion/irritation GHS chapter 3.2 Category 1A or 1B or 1C H314 GHS05

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Iodoacetic Acid hazard statements (H-codes)

Hazard statements assigned to Iodoacetic Acid
CodeHazard statement
H301 Toxic if swallowed.
H314 Causes severe skin burns and eye damage.

This page lists only the codes assigned to Iodoacetic Acid. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Iodoacetic Acid

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Iodoacetic Acid issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Iodoacetic Acid precautionary statements

CLP Annex VI assigns 7 precautionary statements to Iodoacetic Acid. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Iodoacetic Acid name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български йодооцетна киселина
Spanish español Ácido yodoacético
Czech čeština jodoctová kyselina
Danish dansk iodeddikesyre
German Deutsch Iodessigsäure
Estonian eesti jodoäädikhape
Greek ελληνικά ιωδοξικό οξύ
English English iodoacetic acid
French français acide iodoacétique
Croatian hrvatski jodoctena kiselina
Italian italiano acido iodoacetico
Latvian latviešu jodetiķskābe
Lithuanian lietuvių jodacto rūgštis
Hungarian magyar jódecetsav
Maltese Malti aċidu jodoaċetiku
Dutch Nederlands joodazijnzuur
Polish polski kwas jodooctowy
Portuguese português ácido iodoacético
Romanian română acid iodoacetic
Slovak slovenčina kyselina jódoctová
Slovenian slovenščina jodoocetna kislina
Finnish suomi jodietikkahappo
Swedish svenska jodättiksyra

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Iodoacetic Acid GHS label elements

Everything CLP Annex VI fixes for Iodoacetic Acid, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS05 Corrosion pictogram

Danger

Iodoacetic Acid

  • Toxic if swallowed.
  • Causes severe skin burns and eye damage.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • Immediately call a POISON CENTER/doctor/
  • Rinse mouth.
  • Do NOT induce vomiting.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Iodoacetic Acid in the GHS label constructor →

07 · Health hazards

Iodoacetic Acid health hazards and exposure limits

Iodoacetic Acid hazard summary

A strong skin, eye, and mucous membrane irritant; [HSDB] May cause severe burns; [CAMEO] Corrosive to skin; [eChemPortal: ERMA] Causes severe burns; [eChemPortal: ESIS] A corrosive substance that can cause severe injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

Iodoacetic Acid properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Iodoacetic Acid boiling point

Property Value Conditions Source
Boiling point Decomposes decomposes HSDB
Decomposes (NTP, 1992) decomposes CAMEO

Iodoacetic Acid melting point

Property Value Conditions Source
Melting point 210 °C (410 °F) HSDB
82.78 °C (181 °F) CAMEO
82.5 °C (180.5 °F) range, midpoint shown HSDB

Iodoacetic Acid solubility

Property Value Conditions Source
Solubility Soluble in water HSDB
Soluble in alcohol; very slightly soluble in ether HSDB
Soluble in ethanol, petroleum ether; slightly soluble in ether, chloroform HSDB

Iodoacetic Acid corrosivity

Property Value Conditions Source
Corrosivity Corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Iodoacetic Acid storage and handling

Iodoacetic Acid storage conditions

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20 °C.

Source: Hazardous Substances Data Bank (HSDB)

Iodoacetic Acid incompatible materials

Incompatible materials: Strong bases, strong reducing agents.

Source: Hazardous Substances Data Bank (HSDB)

Iodoacetic Acid reactivity

IODOACETIC ACID reacts vigorously with bases and is corrosive. (NTP, 1992)

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Iodoacetic Acid in the storage compatibility matrix →

10 · Questions

Iodoacetic Acid — frequently asked questions

What is the CAS number of Iodoacetic Acid?

The CAS number of Iodoacetic Acid is 64-69-7. Its EC number is 200-590-1.

What is the chemical formula of Iodoacetic Acid?

The molecular formula of Iodoacetic Acid is C2H3IO2 and its molecular weight is 185.95 g/mol.

What does a Iodoacetic Acid label have to show?

Under CLP Annex VI the label for Iodoacetic Acid carries the pictograms Skull and crossbones and Corrosion and the signal word is Danger.

Is Iodoacetic Acid flammable?

CLP Annex VI assigns Iodoacetic Acid no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Iodoacetic Acid a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Iodoacetic Acid. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of Iodoacetic Acid?

The boiling point reported for Iodoacetic Acid is Decomposes, decomposes (HSDB).

What is the melting point of Iodoacetic Acid?

The melting point reported for Iodoacetic Acid is 210 °C (410 °F) (HSDB).

How should Iodoacetic Acid be stored?

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20 °C. (Hazardous Substances Data Bank (HSDB))

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