Substance profile
1,2,3,4-tetrahydronaphthalene
1,2,3,4-tetrahydronaphthalene is a colorless liquid with an odor resembling mixture of benzene & menthol.
01 · Identification
What 1,2,3,4-tetrahydronaphthalene is
1,2,3,4-tetrahydronaphthalene is a colorless liquid with an odor resembling mixture of benzene & menthol. Its molecular formula is C10H12 and its molecular weight is 132.2 g/mol. It boils at 208 °C, melts at -35.8 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
1,2,3,4-tetrahydronaphthalene identifiers and molecular data
1,2,3,4-tetrahydronaphthalene CAS number and EC number
1,2,3,4-tetrahydronaphthalene molecular formula and molecular weight
03 · GHS classification
1,2,3,4-tetrahydronaphthalene hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
1,2,3,4-tetrahydronaphthalene pictograms and signal word
1,2,3,4-tetrahydronaphthalene hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Skin corrosion/irritation GHS chapter 3.2 | Category 2 | H315 | GHS07 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 2 | H411 | GHS09 |
1,2,3,4-tetrahydronaphthalene hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H315 | Causes skin irritation. |
| H319 | Causes serious eye irritation. |
| H411 | Toxic to aquatic life with long lasting effects. |
1,2,3,4-tetrahydronaphthalene supplemental EU statements (EUH)
| Code | Statement |
|---|---|
| EUH019 | May form explosive peroxides. |
This page lists only the codes assigned to 1,2,3,4-tetrahydronaphthal…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 1,2,3,4-tetrahydronaphthal…
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1,2,3,4-tetrahydronaph… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
1,2,3,4-tetrahydronaphthalene precautionary statements
CLP Annex VI assigns 12 precautionary statements to 1,2,3,4-tetrahydronaphthal…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
1,2,3,4-tetrahydronaphthalene name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 1,2,3,4-тетрахидронафтален |
| Spanish español | 1,2,3,4-Tetrahidronaftaleno |
| Czech čeština | 1,2,3,4-tetrahydronaftalen |
| Danish dansk | 1,2,3,4-tetrahydronaphtalen |
| German Deutsch | 1,2,3,4-Tetrahydronaphthalin Tetralin |
| Estonian eesti | 1,2,3,4-tetrahüdronaftaleen |
| Greek ελληνικά | 1,2,3,4-τετραϋδροναφθαλίνιο |
| English English | 1,2,3,4-tetrahydronaphthalene |
| French français | 1,2,3,4-tétrahydronaphtalène |
| Croatian hrvatski | 1,2,3,4-tetrahidronaftalen |
| Italian italiano | diciclopentadiene |
| Latvian latviešu | 1,2,3,4-tetrahidronaftalīns |
| Lithuanian lietuvių | 1,2,3,4-tetrahidronaftalenas |
| Hungarian magyar | 1,2,3,4-tetrahidronaftalin |
| Maltese Malti | 1,2,3,4-tetraidronaftalen |
| Dutch Nederlands | 1,2,3,4-tetrahydronaftaleen |
| Polish polski | 1,2,3,4-tetrahydronaftalen tetralina |
| Portuguese português | 1,2,3,4-tetra-hidronaftaleno |
| Romanian română | 1,2,3,4-tetrahidronaftalină |
| Slovak slovenčina | 1,2,3,4-tetrahydronaftalén |
| Slovenian slovenščina | 1,2,3,4-tetrahidronaftalen |
| Finnish suomi | 1,2,3,4-tetrahydronaftaleeni |
| Swedish svenska | 1,2,3,4-tetrahydronaftalen |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
1,2,3,4-tetrahydronaphthalene GHS label elements
Everything CLP Annex VI fixes for 1,2,3,4-tetrahydronaphthal…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
1,2,3,4-tetrahydronaphthalene
- Causes skin irritation.
- Causes serious eye irritation.
- Toxic to aquatic life with long lasting effects.
- May form explosive peroxides.
- Wash … thoroughly after handling.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF ON SKIN:
- IF IN EYES:
- Get medical advice/attention.
- If skin irritation occurs:
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 1,2,3,4-tetrahydronaphthal… in the GHS label constructor →
07 · Health hazards
1,2,3,4-tetrahydronaphthalene health hazards and exposure limits
1,2,3,4-tetrahydronaphthalene hazard summary
Listed in table of Methemoglobinemia-inducing agents: industrial, environmental, and pharmaceutical; [Sullivan, p. 729]; Tetralin is a skin and mucous membrane irritant. When used in poorly ventilated areas, tetralin may cause central nervous system depression. Ingestion of tetralin has caused green urine and laboratory evidence of liver and kidney injury. [HSDB] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; May cause kidney injury; [ICSC]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
1,2,3,4-tetrahydronaphthalene carcinogenicity classification
Under the conditions of these 2-year inhalation studies, there was some evidence of carcinogenic activity of tetralin in male F344/N rats based on the increased incidence of cortical renal tubule adenoma. The increased incidence of testicular interstitial cell adenoma may have been related to tetralin exposure. There was some evidence of carcinogenic activity of tetralin in female F344/N rats based on the increased incidences of hepatocellular neoplasms and uterine stromal polyp. There was no evidence of carcinogenic activity of tetralin in male B6C3F1 mice exposed to 30, 60, or 120 ppm. There was equivocal evidence of carcinogenic activity of tetralin in female B6C3F1 mice based on the increased incidence of splenic hemangiosarcoma.
Source: US National Toxicology Program · TR-561: Toxicology and Carcinogenesis Studies of Tetralin (CASRN 119-64-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) (2011 )
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
1,2,3,4-tetrahydronaphthalene properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
1,2,3,4-tetrahydronaphthalene boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 207.6 °C (405.7 °F) | at 760 mmHg | HSDB |
| 207.78 °C (406 °F) | at 760 mmHg | CAMEO | |
| 207.6 °C (405.7 °F) | ICSC |
1,2,3,4-tetrahydronaphthalene melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -35.8 °C (-32.4 °F) | HSDB | |
| -30.61 °C (-23.1 °F) | CAMEO |
1,2,3,4-tetrahydronaphthalene density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 0.9586 g/cm³ | HSDB | |
| 0.9702 g/cm³ | at 20 °C | HSDB | |
| 0.974 g/cm³ | at 20 °C | CAMEO |
1,2,3,4-tetrahydronaphthalene solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | MISCIBLE WITH ETHANOL, BUTANOL, ACETONE, BENZENE, PETROLEUM ETHER, CHLOROFORM, &PETROLEUM ETHER, DECALIN; SOL IN METHANOL: 50.6% WT/WT; INSOL IN WATER. | HSDB | |
| SOL IN ANILINE | HSDB | ||
| SOL IN ETHER | HSDB |
1,2,3,4-tetrahydronaphthalene vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 1.03 mmHg | CAMEO | |
| 0.368 mmHg | at 25 °C | HSDB | |
| 0.375 mmHg | at 25 °C | ICSC |
1,2,3,4-tetrahydronaphthalene flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 82.22 °C (180 °F) | HSDB | |
| 71.11 °C (160 °F) | HSDB | ||
| 176 °C (348.8 °F) | Closed cup | HSDB |
1,2,3,4-tetrahydronaphthalene autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 385 °C (725 °F) | HSDB |
1,2,3,4-tetrahydronaphthalene lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 0.8 % by volume | CAMEO | |
| 0.8 % by volume | at 150 °C | HSDB |
1,2,3,4-tetrahydronaphthalene upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 5 % by volume | CAMEO | |
| 5 % by volume | at 150 °C | HSDB |
1,2,3,4-tetrahydronaphthalene vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 4.6 (air = 1) | HSDB |
1,2,3,4-tetrahydronaphthalene odor threshold
| Property | Value | Conditions | Source |
|---|---|---|---|
| Odor threshold | Detection threshold 18 ppm in water, purity not specified. | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
1,2,3,4-tetrahydronaphthal… fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
1,2,3,4-tetrahydronaphthalene fire potential
MODERATE, WHEN EXPOSED TO HEAT OR FLAME; CAN REACT WITH OXIDIZING MATERIALS. SPONTANEOUS HEATING: NO.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
1,2,3,4-tetrahydronaphthalene storage and handling
1,2,3,4-tetrahydronaphthalene peroxide formation
B: Compounds that form peroxides on concentration (distillation/evaporation)
Source: Lab and Research Safety, University of Minnesota
1,2,3,4-tetrahydronaphthalene safe storage
Separated from strong oxidants. Keep in a well-ventilated room. Well closed.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
1,2,3,4-tetrahydronaphthalene storage conditions
IN GENERAL MATERIALS ... TOXIC AS STORED OR WHICH CAN DECOMP INTO TOXIC COMPONENTS ... SHOULD BE STORED IN COOL ... VENTILATED PLACE, OUT OF ... SUN, AWAY FROM ... FIRE HAZARD ... BE PERIODICALLY INSPECTED & MONITORED. INCOMPATIBLE MATERIALS SHOULD BE ISOLATED.
Source: Hazardous Substances Data Bank (HSDB)
1,2,3,4-tetrahydronaphthalene incompatible materials
Prolonged, close contact with air may cause an explosion.
Source: Hazardous Substances Data Bank (HSDB)
1,2,3,4-tetrahydronaphthalene reactivity
TETRAHYDRONAPHTHALENE may react vigorously with strong oxidizing agents. May react exothermically with reducing agents to release hydrogen gas. Oxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick 1979 p.151-154].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 1,2,3,4-tetrahydronaphtha… in the storage compatibility matrix →
11 · Questions
1,2,3,4-tetrahydronaphthalene — frequently asked questions
What is the CAS number of 1,2,3,4-tetrahydronaphthalene?
The CAS number of 1,2,3,4-tetrahydronaphthalene is 119-64-2. Its EC number is 204-340-2.
What is the chemical formula of 1,2,3,4-tetrahydronaphthalene?
The molecular formula of 1,2,3,4-tetrahydronaphthalene is C10H12 and its molecular weight is 132.2 g/mol.
What does a 1,2,3,4-tetrahydronaphthalene label have to show?
Under CLP Annex VI the label for 1,2,3,4-tetrahydronaphthalene carries the pictograms Exclamation mark and Environment and the signal word is Warning.
Is 1,2,3,4-tetrahydronaphthalene flammable?
CLP Annex VI assigns 1,2,3,4-tetrahydronaphthalene no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 82.22 °C (180 °F) (HSDB).
Is 1,2,3,4-tetrahydronaphthalene a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 1,2,3,4-tetrahydronaphthalene. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of 1,2,3,4-tetrahydronaphthalene?
The boiling point reported for 1,2,3,4-tetrahydronaphthalene is 207.6 °C (405.7 °F), at 760 mmHg (HSDB).
What is the melting point of 1,2,3,4-tetrahydronaphthalene?
The melting point reported for 1,2,3,4-tetrahydronaphthalene is -35.8 °C (-32.4 °F) (HSDB).
How should 1,2,3,4-tetrahydronaphthalene be stored?
IN GENERAL MATERIALS ... TOXIC AS STORED OR WHICH CAN DECOMP INTO TOXIC COMPONENTS ... SHOULD BE STORED IN COOL ... VENTILATED PLACE, OUT OF ... SUN, AWAY FROM ... FIRE HAZARD ... BE PERIODICALLY INSPECTED & MONITORED. INCOMPATIBLE MATERIALS SHOULD BE ISOLATED. (Hazardous Substances Data Bank (HSDB))
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