Substance profile
1,2-Dimethoxyethane
1,2-Dimethoxyethane is a water-white liquid with a sharp ethereal odor.
01 · Identification
What 1,2-Dimethoxyethane is
1,2-Dimethoxyethane is a water-white liquid with a sharp ethereal odor. Its molecular formula is C4H10O2 and its molecular weight is 90.12 g/mol. It boils at 85 °C, melts at -58 °C, is miscible with water.
Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.
02 · Identifiers
1,2-Dimethoxyethane identifiers and molecular data
1,2-Dimethoxyethane CAS number and EC number
1,2-Dimethoxyethane molecular formula and molecular weight
Other names for 1,2-Dimethoxyethane
- ethylene glycol dimethyl ether
- EGDME
03 · GHS classification
1,2-Dimethoxyethane hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
1,2-Dimethoxyethane pictograms and signal word
1,2-Dimethoxyethane hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Flammable liquids GHS chapter 2.6 | Category 2 | H225 | GHS02 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 4 | H332 | GHS07 |
1,2-Dimethoxyethane hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H225 | Highly flammable liquid and vapour. |
| H360FD | May damage fertility. May damage the unborn child. |
| H332 | Harmful if inhaled. |
1,2-Dimethoxyethane supplemental EU statements (EUH)
| Code | Statement |
|---|---|
| EUH019 | May form explosive peroxides. |
This page lists only the codes assigned to 1,2-Dimethoxyethane. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 1,2-Dimethoxyethane
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1,2-Dimethoxyethane issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
1,2-Dimethoxyethane precautionary statements
CLP Annex VI assigns 9 precautionary statements to 1,2-Dimethoxyethane. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
1,2-Dimethoxyethane name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 1,2-диметоксиетан диметилов етер на етиленгликолаEGDME |
| Spanish español | 1,2-Dimetoxietano éter dimetílico de etilenglicolEGDME |
| Czech čeština | 1,2-dimethoxyethan ethylenglykoldimethyletherEGDME |
| Danish dansk | 1,2-dimethoxyethan ethylenglycoldimethyletherEDGME |
| German Deutsch | 1,2-Dimethoxyethan EthylenglycoldimethyletherEGDME |
| Estonian eesti | 1,2-dimetoksüetaan etüleenglükooli dimetüüleeterEGDME |
| Greek ελληνικά | 1,2-διμεθοξυαιθάνιο διμεθυλαιθέρας της αιθυλενογλυκόληςEGDME |
| English English | 1,2-dimethoxyethane ethylene glycol dimethyl etherEGDME |
| French français | 1,2-diméthoxyéthane éther diméthylique d'éthylène glycol EGDME |
| Croatian hrvatski | 1,2-dimetoksietan etilen-glikol-dimetil-eterEGDME |
| Italian italiano | 1,2-dimetossietano etilenglicol-dimetiletere dimetilglicol |
| Latvian latviešu | 1,2-dimetoksietāns etilēnglikola dimetilēterisEGDME |
| Lithuanian lietuvių | 1,2-dimetoksietanas etilenglikolio dimetileterisEGDME |
| Hungarian magyar | 1,2-dimetoxietán etilén-glikol-dimetil-éterEGDME |
| Maltese Malti | 1,2-dimetossietan eter tad-dimetil tal-glikol tal-etilenEGDME |
| Dutch Nederlands | 1,2-dimethoxyethaan ethyleenglycoldimethyletherEGDME |
| Polish polski | 1,2-dimetoksyetan eter dimetylowy glikolu etylenowegoEGDME |
| Portuguese português | 1,2-dimetoxietano éter dimetílico de etilenoglicolEGDME |
| Romanian română | 1,2-dimetoxietan eter dimetilic al etilenglicoluluiEGDME |
| Slovak slovenčina | 1,2-dimetoxyetán etylénglykol-dimetyléterEGDME |
| Slovenian slovenščina | 1,2-dimetoksietan etilen glikol dimetil eterEGDME |
| Finnish suomi | 1,2-dimetoksietaani etyleeniglykolidimetyylieetteriEGDME |
| Swedish svenska | 1,2-dimetoxietan etylenglykoldimetyleterEGDME |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
1,2-Dimethoxyethane GHS label elements
Everything CLP Annex VI fixes for 1,2-Dimethoxyethane, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
1,2-Dimethoxyethane
- Highly flammable liquid and vapour.
- May damage fertility. May damage the unborn child.
- Harmful if inhaled.
- May form explosive peroxides.
- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- Keep container tightly closed.
- Use explosion-proof [electrical/ventilating/lighting/…] equipment.
- Use only non-sparking tools.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Use only outdoors or in a well-ventilated area.
- IF INHALED:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Store in a well-ventilated place.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 1,2-Dimethoxyethane in the GHS label constructor →
07 · Health hazards
1,2-Dimethoxyethane health hazards and exposure limits
1,2-Dimethoxyethane hazard summary
A mild skin irritant; Cause weight loss and changes in testicular weight in 2-week constant oral studies of rats; [RTECS] May cause eye irritation; Animal studies have shown testicular injury from repeated oral exposure and delayed offspring development following dermal application during gestation; [Univar MSDS] See Monoglyme.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
1,2-Dimethoxyethane properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
1,2-Dimethoxyethane boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 85 °C (185 °F) | at 760 mmHg | CAMEO |
| 82.5 °C (180.5 °F) | range, midpoint shown, at 760 mmHg | HSDB | |
| 82.5 °C (180.5 °F) | range, midpoint shown | ICSC |
1,2-Dimethoxyethane melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -58 °C (-72.4 °F) | HSDB | |
| -57.78 °C (-72 °F) | CAMEO |
1,2-Dimethoxyethane density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 0.86 g/cm³ | ICSC | |
| 0.8629 g/cm³ | at 20 °C | HSDB | |
| 0.868 g/cm³ | at 20 °C | CAMEO |
1,2-Dimethoxyethane solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | MISCIBLE WITH WATER, ALCOHOL; SOL IN HYDROCARBON SOLVENTS | HSDB | |
| SOL IN CHLOROFORM, ETHER, ACETONE, BENZENE | HSDB | ||
| water solubility = 1.00X10+6 mg/l @ 25 °C | at 25 °C | HSDB |
1,2-Dimethoxyethane vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 48 mmHg | at 20 °C | HSDB |
| 48.0039 mmHg | at 20 °C | ICSC |
1,2-Dimethoxyethane flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | -1.67 °C (29 °F) | HSDB | |
| 0 °C (32 °F) | CAMEO | ||
| -2 °C (28.4 °F) | ICSC |
1,2-Dimethoxyethane autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 201.67 °C (395 °F) | HSDB | |
| 202 °C (395.6 °F) | ICSC |
1,2-Dimethoxyethane lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 1.6 % by volume | CAMEO | |
| A seven year old peroxidised sample exploded during distillation. | HSDB |
1,2-Dimethoxyethane upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 10.4 % by volume | CAMEO |
1,2-Dimethoxyethane vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 3.1 (air = 1) | HSDB |
1,2-Dimethoxyethane critical temperature and pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Critical temperature and pressure | 262.78 °C (505 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
1,2-Dimethoxyethane fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
1,2-Dimethoxyethane fire potential
DANGEROUS, WHEN EXPOSED TO HEAT OR FLAME; CAN REACT VIGOROUSLY WITH OXIDIZING MATERIALS
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
1,2-Dimethoxyethane storage and handling
1,2-Dimethoxyethane peroxide formation
B*: Compounds that form peroxides on concentration (distillation/evaporation)
Source: Lab and Research Safety, University of Minnesota
1,2-Dimethoxyethane safe storage
Cool. Fireproof. Separated from strong oxidants.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
1,2-Dimethoxyethane reactivity
When the solvent, 1,2-DIMETHOXYETHANE, was poured into a funnel previously used to introduce the lithium aluminum hydride, a fire ignited the funnel [MCA Case History 1182(1966)].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 1,2-Dimethoxyethane in the storage compatibility matrix →
11 · Questions
1,2-Dimethoxyethane — frequently asked questions
What is the CAS number of 1,2-Dimethoxyethane?
The CAS number of 1,2-Dimethoxyethane is 110-71-4. Its EC number is 203-794-9.
What is the chemical formula of 1,2-Dimethoxyethane?
The molecular formula of 1,2-Dimethoxyethane is C4H10O2 and its molecular weight is 90.12 g/mol.
What does a 1,2-Dimethoxyethane label have to show?
Under CLP Annex VI the label for 1,2-Dimethoxyethane carries the pictograms Flame, Health hazard and Exclamation mark and the signal word is Danger.
Is 1,2-Dimethoxyethane flammable?
Yes. CLP Annex VI assigns 1,2-Dimethoxyethane H225 — highly flammable liquid and vapour. The flash point reported for it is -1.67 °C (29 °F) (HSDB).
Is 1,2-Dimethoxyethane a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 1,2-Dimethoxyethane. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of 1,2-Dimethoxyethane?
The boiling point reported for 1,2-Dimethoxyethane is 85 °C (185 °F), at 760 mmHg (CAMEO).
What is the melting point of 1,2-Dimethoxyethane?
The melting point reported for 1,2-Dimethoxyethane is -58 °C (-72.4 °F) (HSDB).
How should 1,2-Dimethoxyethane be stored?
CLP Annex VI assigns 1,2-Dimethoxyethane the storage statement P403.
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