Substance profile
1,3,5-triazine-2,4,6-triamine
1,3,5-triazine-2,4,6-triamine is monoclinic prisms.
01 · Identification
What 1,3,5-triazine-2,4,6-triamine is
1,3,5-triazine-2,4,6-triamine is monoclinic prisms. It melts at 354 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
1,3,5-triazine-2,4,6-triamine identifiers and molecular data
1,3,5-triazine-2,4,6-triamine CAS number and EC number
Other names for 1,3,5-triazine-2,4,6-triamine
- melamine
03 · GHS classification
1,3,5-triazine-2,4,6-triamine hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
1,3,5-triazine-2,4,6-triamine pictograms and signal word
1,3,5-triazine-2,4,6-triamine hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Carcinogenicity GHS chapter 3.6 | Category 2 | H351 | GHS08 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 2 | H373 | GHS08 |
1,3,5-triazine-2,4,6-triamine hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H351 | Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
This page lists only the codes assigned to 1,3,5-triazine-2,4,6-triam…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 1,3,5-triazine-2,4,6-triam…
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1,3,5-triazine-2,4,6-t… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
1,3,5-triazine-2,4,6-triamine precautionary statements
CLP Annex VI assigns 7 precautionary statements to 1,3,5-triazine-2,4,6-triam…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
1,3,5-triazine-2,4,6-triamine name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 1,3,5-триазин-2,4,6-триамин меламин |
| Spanish español | 1,3,5-Triazina-2,4,6-triamina melamina |
| Czech čeština | 1,3,5-triazin-2,4,6-triamin melamin |
| Danish dansk | 1,3,5-triazin-2,4,6-triamin melamin |
| German Deutsch | 2,4,6-Triamino-1,3,5-triazin Melamin |
| Estonian eesti | 1,3,5-triasino-2,4,6-triamiin melamiin |
| Greek ελληνικά | 1,3,5-τριαζινο-2,4,6-τριαμίνη μελαμίνη |
| English English | 1,3,5-triazine-2,4,6-triamine melamine |
| French français | 1,3,5-triazine-2,4,6-triamine mélamine |
| Croatian hrvatski | 1,3,5-triazin-2,4,6-triamin melamin |
| Italian italiano | 1,3,5-triazina-2,4,6-triammina melammina |
| Latvian latviešu | 1,3,5-triazīn-2,4,6-triamīns melamīns |
| Lithuanian lietuvių | 1,3,5-triazin-2,4,6-triaminas melaminas |
| Hungarian magyar | 1,3,5-triazin-2,4,6-triamin melamin |
| Maltese Malti | 1,3,5-triażina-2,4,6-triamina melamina |
| Dutch Nederlands | 1,3,5-triazine-2,4,6-triamine melamine |
| Polish polski | 2,4,6-triamino-1,3,5-triazyna melamina |
| Portuguese português | 1,3,5-triazina-2,4,6-triamina melamina |
| Romanian română | 1,3,5-triazin-2,4,6-triamină melamină |
| Slovak slovenčina | 1,3,5-triazin-2,4,6-triamină melamină |
| Slovenian slovenščina | 1,3,5-triazin-2,4,6-triamin melamin |
| Finnish suomi | 1,3,5-triatsiini-2,4,6-triamiini melamiini |
| Swedish svenska | 1,3,5-triazin-2,4,6-triamin melamin |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
1,3,5-triazine-2,4,6-triamine GHS label elements
Everything CLP Annex VI fixes for 1,3,5-triazine-2,4,6-triam…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
1,3,5-triazine-2,4,6-triamine
- Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF exposed or concerned:
- Get medical advice/attention.
- Get medical advice/attention if you feel unwell.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 1,3,5-triazine-2,4,6-triam… in the GHS label constructor →
07 · Health hazards
1,3,5-triazine-2,4,6-triamine health hazards and exposure limits
1,3,5-triazine-2,4,6-triamine hazard summary
Toxic by ingestion; May cause kidney stones; A skin, eye, mucous membrane, and respiratory tract irritant; [CAMEO] An irritant; Effects in high-dose animal studies include abnormal liver function tests; [MSDSonline] No occupational morbidity or mortality reported; [AIHA] Melamine-contaminated pet food caused kidney stones and acute kidney failure in cats and dogs. [Reference #1]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
1,3,5-triazine-2,4,6-triamine carcinogenicity classification
Under the conditions of this bioassay, melamine was carcinogenic for male F344/N rats, causing transitional-cell carcinomas in the urinary bladder. With one exception, urinary bladder stones were observed in male rats that had transitional-cell carcinomas. Melamine was not carcinogenic for female F344/N rats or for B6C3F1 mice of either sex.
Source: US National Toxicology Program · TR-245: Carcinogenesis Bioassay of Melamine (CASRN 108-78-1) in F344/N Rats and B6C3F1 Mice (Feed Study) (1983 )
Cancer Classification: Group D Not Classifiable as to Human Carcinogenicity
Source: Hazardous Substances Data Bank (HSDB)
Evaluation: There is inadequate evidence in humans for the carcinogenicity of melamine. There is sufficient evidence in experimental animals for the carcinogenicity of melamine under conditions in which it produces bladder calculi. Overall evaluation: In making the overall evaluation, the Working Group noted that a non-DNA reactive mechanism by which melamine produced urinary bladder tumors in male rats occurred only under conditions in which calculi were produced. Melamine is not classifiable as to its carcinogenicity to humans (Group 3).
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
1,3,5-triazine-2,4,6-triamine properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
1,3,5-triazine-2,4,6-triamine boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | Sublimes | sublimes | HSDB |
| Sublimes (NTP, 1992) | sublimes | CAMEO |
1,3,5-triazine-2,4,6-triamine melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 354 °C (669.2 °F) | HSDB | |
| 345 °C (653 °F) | above this value | ICSC | |
| 345 °C (653 °F) | decomposes | CAMEO |
1,3,5-triazine-2,4,6-triamine density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.574 g/cm³ | ICSC | |
| 1.573 g/cm³ | at 16.11 °C | CAMEO | |
| 1.573 g/cm³ | at 16 °C | DOE PAC |
1,3,5-triazine-2,4,6-triamine solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Very slightly sol in hot alc; insol in ether | HSDB | |
| Sparingly sol in glycol, glycerol, pyridine; very slightly sol in ethanol; insol in benzene, carbon tetrachloride | HSDB | ||
| In water, 3.23X10+3 mg/L at 20 °C | at 20 °C | HSDB |
1,3,5-triazine-2,4,6-triamine vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 3.59e-10 mmHg | at 20 °C | HSDB |
| 0.0503 mmHg | at 20 °C | ICSC | |
| 50 mmHg | at 315 °C | HSDB |
1,3,5-triazine-2,4,6-triamine autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 260 °C (500 °F) | above this value | CAMEO |
| 500 °C (932 °F) | above this value | ICSC |
1,3,5-triazine-2,4,6-triamine vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 4.34 (air = 1) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
1,3,5-triazine-2,4,6-triamine storage and handling
1,3,5-triazine-2,4,6-triamine storage conditions
Store in tightly closed containers in a cool, well vented area away form strong oxidizers and strong acids. Where possible, automatically pump liquid from drums or other storage containers to process containers. A regulated, marked area should be established where this chemical is handled, used, or stored in compliance with OSHA standard 1910.1045.
Source: Hazardous Substances Data Bank (HSDB)
1,3,5-triazine-2,4,6-triamine incompatible materials
Strong oxidizers, strong acids.
Source: Hazardous Substances Data Bank (HSDB)
1,3,5-triazine-2,4,6-triamine reactivity
MELAMINE is incompatible with strong oxidizing agents and strong acids (NTP, 1992). Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 1,3,5-triazine-2,4,6-tria… in the storage compatibility matrix →
10 · Questions
1,3,5-triazine-2,4,6-triamine — frequently asked questions
What is the CAS number of 1,3,5-triazine-2,4,6-triamine?
The CAS number of 1,3,5-triazine-2,4,6-triamine is 108-78-1. Its EC number is 203-615-4.
What does a 1,3,5-triazine-2,4,6-triamine label have to show?
Under CLP Annex VI the label for 1,3,5-triazine-2,4,6-triamine carries the pictogram Health hazard and the signal word is Warning.
Is 1,3,5-triazine-2,4,6-triamine flammable?
CLP Annex VI assigns 1,3,5-triazine-2,4,6-triamine no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is 1,3,5-triazine-2,4,6-triamine a carcinogen?
CLP Annex VI assigns 1,3,5-triazine-2,4,6-triamine H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive. IARC places it in Group 2B: possibly carcinogenic to humans.
What is the boiling point of 1,3,5-triazine-2,4,6-triamine?
The boiling point reported for 1,3,5-triazine-2,4,6-triamine is Sublimes, sublimes (HSDB).
What is the melting point of 1,3,5-triazine-2,4,6-triamine?
The melting point reported for 1,3,5-triazine-2,4,6-triamine is 354 °C (669.2 °F) (HSDB).
How should 1,3,5-triazine-2,4,6-triamine be stored?
Store in tightly closed containers in a cool, well vented area away form strong oxidizers and strong acids. Where possible, automatically pump liquid from drums or other storage containers to process containers. A regulated, marked area should be established where this chemical is handled, used, or stored in compliance with OSHA standard 1910.1045. (Hazardous Substances Data Bank (HSDB))
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