Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione

1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione is a white crystalline solid with a no odor at room temperature.

CAS 2451-62-9 Danger

01 · Identification

What 1,3,5-tris(oxiranylmethyl)-1,3… is

1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione is a white crystalline solid with a no odor at room temperature. It boils at 240 °C, melts at 95 °C.

Under the GHS it carries the signal word Danger.

02 · Identifiers

1,3,5-tris(oxiranylmethyl)-1,3… identifiers and molecular data

1,3,5-tris(oxiranylmethyl)-1,3… CAS number and EC number

CAS number2451-62-9
EC number219-514-3
Index number (CLP Annex VI)615-021-00-6

Other names for 1,3,5-tris(oxiranylmethyl)-1,3…

  • TGIC

03 · GHS classification

1,3,5-tris(oxiranylmethyl)-1,3… hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

1,3,5-tris(oxiranylmethyl)-1,3… pictograms and signal word

Signal wordDanger

1,3,5-tris(oxiranylmethyl)-1,3… hazard class and category

GHS hazard classes 1,3,5-tris(oxiranylmethyl)… falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - inhalation GHS chapter 3.1 Category 3 H331 GHS06
Serious eye damage/eye irritation GHS chapter 3.3 Category 1 H318 GHS05
Skin sensitisation GHS chapter 3.4 Category 1 or 1A or 1B H317 GHS07
Germ cell mutagenicity GHS chapter 3.5 Category 1A or 1B H340 GHS08
Specific target organ toxicity - repeated exposure GHS chapter 3.9 Category 2 H373 GHS08
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 3 H412

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

1,3,5-tris(oxiranylmethyl)-1,3… hazard statements (H-codes)

Hazard statements assigned to 1,3,5-tris(oxiranylmethyl)…
CodeHazard statement
H340 May cause genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H331 Toxic if inhaled.
H301 Toxic if swallowed.
H373 May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H318 Causes serious eye damage.
H317 May cause an allergic skin reaction.
H412 Harmful to aquatic life with long lasting effects.

This page lists only the codes assigned to 1,3,5-tris(oxiranylmethyl)…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 1,3,5-tris(oxiranylmethyl)…

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1,3,5-tris(oxiranylmet… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

1,3,5-tris(oxiranylmethyl)-1,3… precautionary statements

CLP Annex VI assigns 19 precautionary statements to 1,3,5-tris(oxiranylmethyl)…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

1,3,5-tris(oxiranylmethyl)-1,3… name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български 1,3,5-трис(оксиранилметил)-1,3,5-триазин-2,4,6(1 H ,3 H ,5 H )-трион TGIC
Spanish español 1,3,5-Tris(oxiranilmetil)-1,3,5-triazina-2,4,6(1 H ,3 H ,5 H )-triona TGIC
Czech čeština 1,3,5-tris(2,3-epoxypropyl)-1,3,5-triazin-2(1 H ),4(3 H ),6(5 H )-trion TGIC
Danish dansk 1,3,5-tris(oxiranylmethyl)-1,3,5-triazin-2,4,6(1 H, 3 H, 5 H )-trion TGIC
German Deutsch 1,3,5-Tris(oxiranylmethyl)-1,3,5-triazin-2,4,6(1 H ,3 H ,5 H )trion TGICTriglycidylisocyanurat
Estonian eesti 1,3,5-tris(oksiranüülmetüül)-1,3,5-triasiin-2,4,6-(1 H ,3 H ,5 H )-trioon TGIC
Greek ελληνικά 1,3,5,-τρις(οξιρανυλομεθυλο)-1,3,5-τριαζινο-2,4,6(1 H ,3 H ,5 H )-τριόνη TGIC
English English 1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1 H ,3 H ,5 H )-trione TGIC
French français 1,3,5-tris(oxiranylméthyl)-1,3,5-triazine-2,4,6(1 H ,3 H ,5 H )-trione TGIC
Croatian hrvatski 1,3,5-tris(oksiranilmetil)-1,3,5-triazin-2,4,6(1 H ,3 H ,5 H )-trion TGIC
Italian italiano 1,3,5-tris(ossiranilmetil)-1,3,5-triazin-2,4,6(1 H ,3 H ,5 H )-trione TGIC
Latvian latviešu 1,3,5-tris(oksiranilmetil)-1,3,5-triazīn-2,4,6(1 H ,3 H ,5 H )-trions TGIC
Lithuanian lietuvių 1,3,5-tri(oksiranilmetil)-1,3,5-triazin-2,4,6(1 H ,3 H ,5 H )-trionas TGIC
Hungarian magyar 1,3,5-trisz(oxiranilmetil)-1,3,5-triazin-2,4,6-(1 H ,3 H ,5 H )-trion TGIC
Maltese Malti 1,3,5-tris(ossiranilmetil)-1,3,5-triażina-2,4,6(1 H ,3 H ,5 H )-trion TGIC
Dutch Nederlands 1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1 H ,3 H ,5 H )-trion TGIC
Polish polski 1,3,5-tris(oksiranylometylo)-1,3,5-triazyno-2,4,6(1 H ,3 H ,5 H )-trion TGIC
Portuguese português 1,3,5-tris(oxiranilmetil)-1,3,5-triazina-2,4,6-(1 H ,3 H ,5 H )-triona TGIC
Romanian română 1,3,5-tris(oxiranilmetil)-1,3,5-triazin-2,4,6(1 H ,3 H ,5 H )-trionă TGIC
Slovak slovenčina 1,3,5-tris(oxiranylmetyl)-1,3,5-triazín-2,4,6(1 H ,3 H ,5 H )-trión TGIC
Slovenian slovenščina 1,3,5-tris(oksiranilmetil)-1,3,5-triazin-2,4,6(1 H ,3 H ,5 H )-trion TGIC
Finnish suomi 1,3,5-tris(oksiranyylimetyyli)-1,3,5-triatsiini-2,4,6(1 H ,3 H ,5 H )-trioni TGIC
Swedish svenska 1,3,5-tris(oxiranylmetyl)-1,3,5-triazin-2,4,6(1 H ,3 H ,5 H )-trion TGIC

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

1,3,5-tris(oxiranylmethyl)-1,3… GHS label elements

Everything CLP Annex VI fixes for 1,3,5-tris(oxiranylmethyl)…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS08 Health hazard pictogramGHS05 Corrosion pictogram

Danger

1,3,5-tris(oxiranylmethyl)-1,3…

  • May cause genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Toxic if inhaled.
  • Toxic if swallowed.
  • May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Causes serious eye damage.
  • May cause an allergic skin reaction.
  • Harmful to aquatic life with long lasting effects.
  • Obtain special instructions before use.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Avoid breathing dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Contaminated work clothing should not be allowed out of the workplace.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF INHALED:
  • IF IN EYES:
  • IF exposed or concerned:
  • Immediately call a POISON CENTER/doctor/
  • Get medical advice/attention.
  • Get medical advice/attention if you feel unwell.
  • Rinse mouth.
  • If skin irritation or rash occurs:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 1,3,5-tris(oxiranylmethyl)… in the GHS label constructor →

07 · Health hazards

1,3,5-tris(oxiranylmethyl)-1,3… health hazards and exposure limits

1,3,5-tris(oxiranylmethyl)-1,3… hazard summary

A nonsmoking spray painter, after using a polyester powder paint containing 4% TGIC for four years, developed allergic contact dermatitis and work-related asthma. The painter had negative skin tests for common allergens and negative challenge test with lactose powder. A challenge test with 4% TGIC induced a dual response with a late 23% fall in FEV1. [Piirila P, et al. Occupational Asthma Caused by Triglycidyl Isocyanurate (TGIC). Clin Exp Allergy 1997 May;27(5):510-4] TGIC causes male reproductive damage in high-dose animal studies. [ACGIH] A severe eye irritant; May cause skin sensitization; [ICSC] Danger of skin and airway sensitization; [MAK]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

1,3,5-tris(oxiranylmethyl)-1,3… properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

1,3,5-tris(oxiranylmethyl)-1,3… boiling point

Property Value Conditions Source
Boiling point 240 °C (464 °F) above this value HSDB
210 °C (410 °F) at 0.2 mmHg (reduced pressure) HSDB

1,3,5-tris(oxiranylmethyl)-1,3… melting point

Property Value Conditions Source
Melting point 95 °C (203 °F) HSDB
96.39 °C (205.5 °F) range, midpoint shown HSDB

1,3,5-tris(oxiranylmethyl)-1,3… density

Property Value Conditions Source
Density 142-144 at 20 °C at 20 °C HSDB

1,3,5-tris(oxiranylmethyl)-1,3… solubility

Property Value Conditions Source
Solubility Exists as a mixture of 2 pairs of diastereomer racemates, designated alpha and beta, that are separable on the basis of their solubility properties HSDB
log Kow: -0.8. Solubility in water: 0.9 g/100 mL at 25 °C at 25 °C, Triglycidyl isocyanurate technical grade HSDB
In water, 9-10.5 g/L at 25 °C, pH 5-8 at 25 °C HSDB

1,3,5-tris(oxiranylmethyl)-1,3… vapor pressure

Property Value Conditions Source
Vapor pressure 0.0000525 mmHg below this value, at 20 °C HSDB

1,3,5-tris(oxiranylmethyl)-1,3… flash point

Property Value Conditions Source
Flash point 170 °C (338 °F) Open cup vs. closed cup not specified HSDB
170 °C (338 °F) above this value, technical grade ICSC

1,3,5-tris(oxiranylmethyl)-1,3… autoignition temperature

Property Value Conditions Source
Autoignition temperature 200 °C (392 °F) above this value, technical grade ICSC

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

1,3,5-tris(oxiranylmethyl)… fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

1,3,5-tris(oxiranylmethyl)-1,3… fire potential

A combustible liquid.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

1,3,5-tris(oxiranylmethyl)-1,3… storage and handling

1,3,5-tris(oxiranylmethyl)-1,3… safe storage

Well closed.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

1,3,5-tris(oxiranylmethyl)-1,3… storage conditions

Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects.

Source: Hazardous Substances Data Bank (HSDB)

1,3,5-tris(oxiranylmethyl)-1,3… incompatible materials

Incompatible materials: Strong oxidizing agents.

Source: Hazardous Substances Data Bank (HSDB)

1,3,5-tris(oxiranylmethyl)-1,3… reactivity

Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 1,3,5-tris(oxiranylmethyl… in the storage compatibility matrix →

11 · Questions

1,3,5-tris(oxiranylmethyl)-1,3… — frequently asked questions

What is the CAS number of 1,3,5-tris(oxiranylmethyl)-1,3…?

The CAS number of 1,3,5-tris(oxiranylmethyl)-1,3… is 2451-62-9. Its EC number is 219-514-3.

What does a 1,3,5-tris(oxiranylmethyl)-1,3… label have to show?

Under CLP Annex VI the label for 1,3,5-tris(oxiranylmethyl)-1,3… carries the pictograms Skull and crossbones, Health hazard and Corrosion and the signal word is Danger.

Is 1,3,5-tris(oxiranylmethyl)-1,3… flammable?

CLP Annex VI assigns 1,3,5-tris(oxiranylmethyl)-1,3… no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 170 °C (338 °F), Open cup vs. closed cup not specified (HSDB).

Is 1,3,5-tris(oxiranylmethyl)-1,3… a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for 1,3,5-tris(oxiranylmethyl)-1,3…. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of 1,3,5-tris(oxiranylmethyl)-1,3…?

The boiling point reported for 1,3,5-tris(oxiranylmethyl)-1,3… is 240 °C (464 °F), above this value (HSDB).

What is the melting point of 1,3,5-tris(oxiranylmethyl)-1,3…?

The melting point reported for 1,3,5-tris(oxiranylmethyl)-1,3… is 95 °C (203 °F) (HSDB).

How should 1,3,5-tris(oxiranylmethyl)-1,3… be stored?

Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects. (Hazardous Substances Data Bank (HSDB))

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