Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

2-(2-methoxyethoxy)ethanol

2-(2-methoxyethoxy)ethanol is a colorless liquid with a slight or pleasant smell.

CAS 111-77-3 Danger

01 · Identification

What 2-(2-methoxyethoxy)ethanol is

2-(2-methoxyethoxy)ethanol is a colorless liquid with a slight or pleasant smell. It boils at 193 °C, melts at -70 °C, is miscible with water.

Under the GHS it carries the signal word Danger.

02 · Identifiers

2-(2-methoxyethoxy)ethanol identifiers and molecular data

2-(2-methoxyethoxy)ethanol CAS number and EC number

CAS number111-77-3
EC number203-906-6
Index number (CLP Annex VI)603-107-00-6

Other names for 2-(2-methoxyethoxy)ethanol

  • diethylene glycol monomethyl ether

03 · GHS classification

2-(2-methoxyethoxy)ethanol hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

2-(2-methoxyethoxy)ethanol pictograms and signal word

Signal wordDanger

2-(2-methoxyethoxy)ethanol hazard statements (H-codes)

Hazard statements assigned to 2-(2-methoxyethoxy)ethanol
CodeHazard statement
H360D May damage the unborn child.

This page lists only the codes assigned to 2-(2-methoxyethoxy)ethanol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 2-(2-methoxyethoxy)ethanol

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2-(2-methoxyethoxy)eth… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

2-(2-methoxyethoxy)ethanol precautionary statements

CLP Annex VI assigns 4 precautionary statements to 2-(2-methoxyethoxy)ethanol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Response

What to do once exposure, spillage or fire has already happened.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

2-(2-methoxyethoxy)ethanol name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български 2-(2-метоксиетокси)етанол монометилов етер на диетиленгликола
Spanish español 2-(2-Metoxietoxi)etanol éter monometílico de dietilenglicol
Czech čeština 2-(2-methoxyethoxy)ethanol diethylenglykolmonomethylether
Danish dansk 2-(2-methoxyethoxy)ethanol diethylenglycolmonomethylether
German Deutsch 2-(2-Methoxyethoxy)ethanol Diethylenglykolmonomethylether
Estonian eesti 2-(2-metoksüetoksü)etanool dietüleenglükoolmonometüüleeter
Greek ελληνικά 2-(2-μεθοξυαιθοξυ)αιθανόλη μονομεθυλαιθέρας διαιθυλενογλυκόλης
English English 2-(2-methoxyethoxy)ethanol diethylene glycol monomethyl ether
French français 2-(2-méthoxyéthoxy)éthanol éther monométhylique du diéthylène glycol
Croatian hrvatski 2-(2-metoksietoksi)etanol dietilen-glikol-monometil-eter
Italian italiano 2-(2-metossietossi)etanolo glicol dietilenico monometiletere
Latvian latviešu 2-(2-metoksietoksi)etanols dietiletilēnglikola monometilēteris
Lithuanian lietuvių 2-(2-metoksietoksi)etanolis dietilenglikolio monometileteris
Hungarian magyar 2-(2-metoxietoxi)etanol dietilén-glikol-monometil-éter
Maltese Malti 2-(2-metossietossi)etanol monometiletere glikol dietileniku
Dutch Nederlands 2-(2-methoxyethoxy)ethanol diëthyleenglycolmonomethylether
Polish polski 2-(2-metoksyetoksy)etanol eter monometylowy glikolu dietylenowego
Portuguese português 2-(2-metoxietoxi)etanol éter monometílico de dietilenoglicol
Romanian română 2-(2-metoxietoxi)etanol dietilenglicol monometil eter
Slovak slovenčina 2-(2-metoxyetoxy)etanol dietylénglykol monometyléter
Slovenian slovenščina 2-(2-metoksietoksi)etanol dietilen glikol monometil eter
Finnish suomi 2-(2-metoksietoksi)etanoli dietyleeniglykolin monometyylieetteri
Swedish svenska 2-(2-metoxietoxi)etanol dietylenglykolmonometyleter

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

2-(2-methoxyethoxy)ethanol GHS label elements

Everything CLP Annex VI fixes for 2-(2-methoxyethoxy)ethanol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogram

Danger

2-(2-methoxyethoxy)ethanol

  • May damage the unborn child.
  • Obtain special instructions before use.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF exposed or concerned:
  • Get medical advice/attention.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 2-(2-methoxyethoxy)ethanol in the GHS label constructor →

07 · Health hazards

2-(2-methoxyethoxy)ethanol health hazards and exposure limits

2-(2-methoxyethoxy)ethanol hazard summary

Defats the skin; Can be absorbed through the skin; Animal tests show that this substance possibly causes toxicity to human reproduction or development. [ICSC] Labeled as May impair fertility and May cause harm to the unborn child by EU regulations; [Glycol Ethers Online] Readily oxidizes in air forming unstable peroxides that can spontaneously explode; May cause eye irritation; [CAMEO] An irritant; [MSDSonline] See GLYCOL ETHERS.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

2-(2-methoxyethoxy)ethanol properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

2-(2-methoxyethoxy)ethanol boiling point

Property Value Conditions Source
Boiling point 193 °C (379.4 °F) HSDB
193.89 °C (381 °F) at 760 mmHg CAMEO

2-(2-methoxyethoxy)ethanol melting point

Property Value Conditions Source
Melting point -70 °C (-94 °F) CAMEO
-84 °C (-119.2 °F) below this value HSDB

2-(2-methoxyethoxy)ethanol density

Property Value Conditions Source
Density 1.04 g/cm³ ICSC
1.035 g/cm³ at 20 °C HSDB
1.025 g/cm³ at 20 °C CAMEO

2-(2-methoxyethoxy)ethanol solubility

Property Value Conditions Source
Solubility Miscible /1X10+6 mg/L/ with water HSDB
Miscible with alcohol, glycerol, ether, acetone, dimethylformamide HSDB
Very soluble in ethanol, ethyl ether HSDB

2-(2-methoxyethoxy)ethanol vapor pressure

Property Value Conditions Source
Vapor pressure 0.2 mmHg at 20 °C CAMEO
0.225 mmHg at 20 °C ICSC
0.25 mmHg at 25 °C HSDB

2-(2-methoxyethoxy)ethanol flash point

Property Value Conditions Source
Flash point 96.11 °C (205 °F) HSDB
93.33 °C (200 °F) CAMEO
93 °C (199.4 °F) ICSC

2-(2-methoxyethoxy)ethanol autoignition temperature

Property Value Conditions Source
Autoignition temperature 240.56 °C (465 °F) HSDB
215 °C (419 °F) ICSC

2-(2-methoxyethoxy)ethanol lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 1.2 % by volume HSDB
1.38 % by volume HSDB
1.5 % by volume CAMEO

2-(2-methoxyethoxy)ethanol upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 22.7 % by volume HSDB
9.5 % by volume CAMEO
18.1 % by volume ICSC

2-(2-methoxyethoxy)ethanol vapor density

Property Value Conditions Source
Vapor density 4.14 (air = 1) HSDB
4.1 (air = 1) ICSC

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

2-(2-methoxyethoxy)ethanol fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

2-(2-methoxyethoxy)ethanol fire potential

Combustible

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

2-(2-methoxyethoxy)ethanol storage and handling

2-(2-methoxyethoxy)ethanol safe storage

Separated from strong oxidants. Ventilation along the floor.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

2-(2-methoxyethoxy)ethanol storage conditions

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store under inert gas. Hygroscopic.

Source: Hazardous Substances Data Bank (HSDB)

2-(2-methoxyethoxy)ethanol incompatible materials

Contact of the solid hypochlorite with glycerol, diethylene glycol monomethyl ether or phenol causes ignition within a few min, accompanied by irritant smoke, especially with phenol (formation of chlorophenols).

Source: Hazardous Substances Data Bank (HSDB)

2-(2-methoxyethoxy)ethanol reactivity

DIETHYLENE GLYCOL MONOMETHYL ETHER is a ether-alcohol derivative. The ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 2-(2-methoxyethoxy)ethano… in the storage compatibility matrix →

11 · Transport

2-(2-methoxyethoxy)ethanol UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

2-(2-methoxyethoxy)ethanol under UN 3055 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
2-(2-AMINOETHOXY) ETHANOL 8 C7 III
  • ADR label model 8 — Corrosive substance
8

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 8 is “Corrosive substances” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
2-(2-Aminoethoxy) ethanol 8 III
  • US DOT CORROSIVE label (§172.442)
8

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 8 is “Corrosive material” (49 CFR 173.2).

Full UN 3055 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

2-(2-methoxyethoxy)ethanol — frequently asked questions

What is the CAS number of 2-(2-methoxyethoxy)ethanol?

The CAS number of 2-(2-methoxyethoxy)ethanol is 111-77-3. Its EC number is 203-906-6.

What does a 2-(2-methoxyethoxy)ethanol label have to show?

Under CLP Annex VI the label for 2-(2-methoxyethoxy)ethanol carries the pictogram Health hazard and the signal word is Danger.

Is 2-(2-methoxyethoxy)ethanol flammable?

CLP Annex VI assigns 2-(2-methoxyethoxy)ethanol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 96.11 °C (205 °F) (HSDB).

Is 2-(2-methoxyethoxy)ethanol a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for 2-(2-methoxyethoxy)ethanol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of 2-(2-methoxyethoxy)ethanol?

The boiling point reported for 2-(2-methoxyethoxy)ethanol is 193 °C (379.4 °F) (HSDB).

What is the melting point of 2-(2-methoxyethoxy)ethanol?

The melting point reported for 2-(2-methoxyethoxy)ethanol is -70 °C (-94 °F) (CAMEO).

How should 2-(2-methoxyethoxy)ethanol be stored?

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store under inert gas. Hygroscopic. (Hazardous Substances Data Bank (HSDB))

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