Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

2,3,4,6-Tetrachlorophenol

2,3,4,6-Tetrachlorophenol is needles from ligroin, acetic acid with a strong odor.

CAS 58-90-2 C6H2Cl4O 231.9 g/mol Danger

01 · Identification

What 2,3,4,6-Tetrachlorophenol is

2,3,4,6-Tetrachlorophenol is needles from ligroin, acetic acid with a strong odor. Its molecular formula is C6H2Cl4O and its molecular weight is 231.9 g/mol. It melts at 70 °C.

Under the GHS it carries the signal word Danger. It is classed as carcinogens.

02 · Identifiers

2,3,4,6-Tetrachlorophenol identifiers and molecular data

2,3,4,6-Tetrachlorophenol CAS number and EC number

CAS number58-90-2
EC number200-402-8
Index number (CLP Annex VI)604-013-00-8

2,3,4,6-Tetrachlorophenol molecular formula and molecular weight

Molecular formulaC6H2Cl4O
Molecular weight231.9 g/mol
Chemical class Carcinogens

03 · GHS classification

2,3,4,6-Tetrachlorophenol hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

2,3,4,6-Tetrachlorophenol pictograms and signal word

Signal wordDanger

2,3,4,6-Tetrachlorophenol hazard class and category

GHS hazard classes 2,3,4,6-Tetrachlorophenol falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Skin corrosion/irritation GHS chapter 3.2 Category 2 H315 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

2,3,4,6-Tetrachlorophenol hazard statements (H-codes)

Hazard statements assigned to 2,3,4,6-Tetrachlorophenol
CodeHazard statement
H301 Toxic if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to 2,3,4,6-Tetrachlorophenol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 2,3,4,6-Tetrachlorophenol

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2,3,4,6-Tetrachlorophe… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

2,3,4,6-Tetrachlorophenol precautionary statements

CLP Annex VI assigns 16 precautionary statements to 2,3,4,6-Tetrachlorophenol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

2,3,4,6-Tetrachlorophenol name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български 2,3,4,6-тетрахлорофенол
Spanish español 2,3,4,6-Tetraclorofenol
Czech čeština 2,3,4,6-tetrachlorfenol
Danish dansk 2,3,4,6-tetrachlorphenol
German Deutsch 2,3,4,6-Tetrachlorphenol
Estonian eesti 2,3,4,6-tetraklorofenool
Greek ελληνικά 2,3,4,6-τετραχλωροφαινόλη
English English 2,3,4,6-tetrachlorophenol
French français 2,3,4,6-tétrachlorophénol
Croatian hrvatski 2,3,4,6-tetraklorfenol
Italian italiano 2,3,4,6-tetraclorofenolo
Latvian latviešu 2,3,4,6-tetrahlorfenols
Lithuanian lietuvių 2,3,4,6-tetrachlorfenolis
Hungarian magyar 2,3,4,6-tetraklórfenol
Maltese Malti 2,3,4,6-tetraklorofenol
Dutch Nederlands 2,3,4,6-tetrachloorfenol
Polish polski 2,3,4,6-tetrachlorofenol
Portuguese português 2,3,4,6-tetraclorofenol
Romanian română 2,3,4,6-tetraclorofenol
Slovak slovenčina 2,3,4,6-tetrachlórfenol
Slovenian slovenščina 2,3,4,6-tetraklorofenol
Finnish suomi 2,3,4,6-tetrakloorifenoli
Swedish svenska 2,3,4,6-tetraklorfenol

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

2,3,4,6-Tetrachlorophenol GHS label elements

Everything CLP Annex VI fixes for 2,3,4,6-Tetrachlorophenol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS09 Environment pictogram

Danger

2,3,4,6-Tetrachlorophenol

  • Toxic if swallowed.
  • Causes skin irritation.
  • Causes serious eye irritation.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Wash thoroughly after handling.
  • Do not eat, drink or smoke when using this product.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF IN EYES:
  • Immediately call a POISON CENTER/doctor/
  • Get medical advice/attention.
  • Rinse mouth.
  • If skin irritation occurs:
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 2,3,4,6-Tetrachlorophenol in the GHS label constructor →

07 · Health hazards

2,3,4,6-Tetrachlorophenol health hazards and exposure limits

2,3,4,6-Tetrachlorophenol hazard summary

A nose, throat, and respiratory tract irritant; [HSDB] Prolonged contact corrosive to eyes; May cause skin burns, hyperthermia, methemoglobinemia, liver and kidney damage, and convulsions; [CAMEO] A skin, eye, and respiratory tract irritant; May cause liver injury and chloracne; [ICSC] A severe skin and eye irritant; A mucous membrane and upper respiratory tract irritant; May cause liver damage; Effects in high-dose animal studies include convulsions or effect on seizure threshold; [MSDSonline] See CHLOROPHENOLS.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

2,3,4,6-Tetrachlorophenol carcinogenicity classification

Evaluation: There is limited evidence in humans for the carcinogenicity of combined exposures to polychlorophenols or to their sodium salts. ... Overall evaluation: Combined exposures to polychlorophenols or to their sodium salts are possibly carcinogenic to humans (Group 2B). /Polychlorophenols/

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

2,3,4,6-Tetrachlorophenol properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

2,3,4,6-Tetrachlorophenol boiling point

Property Value Conditions Source
Boiling point 64 °C (147.2 °F) at 22.5019 mmHg (reduced pressure) HSDB
150 °C (302 °F) at 15 mmHg (reduced pressure) CAMEO

2,3,4,6-Tetrachlorophenol melting point

Property Value Conditions Source
Melting point 70 °C (158 °F) HSDB

2,3,4,6-Tetrachlorophenol density

Property Value Conditions Source
Density 1.8 g/cm³ ICSC
1.839 g/cm³ at 25 °C HSDB

2,3,4,6-Tetrachlorophenol solubility

Property Value Conditions Source
Solubility SLIGHTLY SOL IN HOT WATER; VERY SOL IN SODIUM HYDROXIDE; SOL IN HOT ACETIC ACID. HSDB
SOL IN ACETONE. HSDB
In water, 0.10 g/100 g water (temperature not specified). HSDB

2,3,4,6-Tetrachlorophenol vapor pressure

Property Value Conditions Source
Vapor pressure 0.0042 mmHg at 25 °C HSDB
1 mmHg at 100 °C CAMEO
0.0042 mmHg Haz-Map

2,3,4,6-Tetrachlorophenol flash point

Property Value Conditions Source
Flash point 100 °C (212 °F) ICSC

2,3,4,6-Tetrachlorophenol odor threshold

Property Value Conditions Source
Odor threshold Odor threshold conc: 0.915-47.0 mg/l; detection: 0.6 mg/l. HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

2,3,4,6-Tetrachlorophenol storage and handling

2,3,4,6-Tetrachlorophenol safe storage

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store in an area without drain or sewer access.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

2,3,4,6-Tetrachlorophenol storage conditions

MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMPOSE INTO TOXIC COMPONENTS ... SHOULD BE STORED IN A COOL WELL VENTILATED PLACE, OUT THE DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, AND SHOULD BE PERIODICALLY INSPECTED ... INCOMPATIBLE MATERIALS SHOULD BE ISOLATED ...

Source: Hazardous Substances Data Bank (HSDB)

2,3,4,6-Tetrachlorophenol reactivity

2,3,4,6-TETRACHLOROPHENOL reacts as a weak organic acid and is incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. May generate heat with bases. Such heating may initiate polymerization.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 2,3,4,6-Tetrachlorophenol in the storage compatibility matrix →

10 · Questions

2,3,4,6-Tetrachlorophenol — frequently asked questions

What is the CAS number of 2,3,4,6-Tetrachlorophenol?

The CAS number of 2,3,4,6-Tetrachlorophenol is 58-90-2. Its EC number is 200-402-8.

What is the chemical formula of 2,3,4,6-Tetrachlorophenol?

The molecular formula of 2,3,4,6-Tetrachlorophenol is C6H2Cl4O and its molecular weight is 231.9 g/mol.

What does a 2,3,4,6-Tetrachlorophenol label have to show?

Under CLP Annex VI the label for 2,3,4,6-Tetrachlorophenol carries the pictograms Skull and crossbones and Environment and the signal word is Danger.

Is 2,3,4,6-Tetrachlorophenol flammable?

CLP Annex VI assigns 2,3,4,6-Tetrachlorophenol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 100 °C (212 °F) (ICSC).

Is 2,3,4,6-Tetrachlorophenol a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for 2,3,4,6-Tetrachlorophenol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of 2,3,4,6-Tetrachlorophenol?

The boiling point reported for 2,3,4,6-Tetrachlorophenol is 64 °C (147.2 °F), at 22.5019 mmHg (reduced pressure) (HSDB).

What is the melting point of 2,3,4,6-Tetrachlorophenol?

The melting point reported for 2,3,4,6-Tetrachlorophenol is 70 °C (158 °F) (HSDB).

How should 2,3,4,6-Tetrachlorophenol be stored?

MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMPOSE INTO TOXIC COMPONENTS ... SHOULD BE STORED IN A COOL WELL VENTILATED PLACE, OUT THE DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, AND SHOULD BE PERIODICALLY INSPECTED ... INCOMPATIBLE MATERIALS SHOULD BE ISOLATED ... (Hazardous Substances Data Bank (HSDB))

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