Substance profile
5-Methyl-3-heptanone
5-Methyl-3-heptanone: liquid.
01 · Identification
What 5-Methyl-3-heptanone is
5-Methyl-3-heptanone: liquid. Its molecular formula is C8H16O and its molecular weight is 128.21 g/mol. It boils at 157 °C, melts at -56.7 °C, is practically insoluble in water.
Under the GHS it carries the signal word Warning. It is classed as flammable agents - 2nd degree.
02 · Identifiers
5-Methyl-3-heptanone identifiers and molecular data
5-Methyl-3-heptanone CAS number and EC number
5-Methyl-3-heptanone molecular formula and molecular weight
Other names for 5-Methyl-3-heptanone
- 5-methylheptan-3-one
03 · GHS classification
5-Methyl-3-heptanone hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
5-Methyl-3-heptanone pictograms and signal word
5-Methyl-3-heptanone hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Flammable liquids GHS chapter 2.6 | Category 3 | H226 | GHS02 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 | H335 | GHS07 |
5-Methyl-3-heptanone hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H226 | Flammable liquid and vapour. |
| H335 | May cause respiratory irritation. |
| H319 | Causes serious eye irritation. |
This page lists only the codes assigned to 5-Methyl-3-heptanone. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 5-Methyl-3-heptanone
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 5-Methyl-3-heptanone issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
5-Methyl-3-heptanone precautionary statements
CLP Annex VI assigns 11 precautionary statements to 5-Methyl-3-heptanone. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
5-Methyl-3-heptanone name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 5-метилхептан-3-он |
| Spanish español | 5-Metilheptan-3-ona |
| Czech čeština | 5-methylheptan-3-on |
| Danish dansk | 5-methyl-3-heptanon |
| German Deutsch | 5-Methyl-3-heptanon |
| Estonian eesti | 5-metüülheptaan-3-oon |
| Greek ελληνικά | 5-μεθυλοεπταν-3-όνη |
| English English | 5-methylheptan-3-one |
| French français | 5-méthylheptan-3-one |
| Croatian hrvatski | 5-metilheptan-3-on |
| Italian italiano | 5-metil-3-eptanone |
| Latvian latviešu | 5-metilheptān-3-ons |
| Lithuanian lietuvių | 5-metil-3-heptanonas |
| Hungarian magyar | 5-metilheptán-3-on |
| Maltese Malti | 5-metilettan-3-on |
| Dutch Nederlands | 5-methylheptaan-3-on |
| Polish polski | 5-metyloheptan-3-on keton etylowo-sec-amylowyetylo-sec-amyloketon |
| Portuguese português | 5-metil-3-heptanona |
| Romanian română | 5-metilheptan-3-onă |
| Slovak slovenčina | 5-metylheptán-3-ón |
| Slovenian slovenščina | 5-metilheptan-3-on |
| Finnish suomi | 5-metyyliheptan-3-oni |
| Swedish svenska | 5-metylheptan-3-on |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
5-Methyl-3-heptanone GHS label elements
Everything CLP Annex VI fixes for 5-Methyl-3-heptanone, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
5-Methyl-3-heptanone
- Flammable liquid and vapour.
- May cause respiratory irritation.
- Causes serious eye irritation.
- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- Keep container tightly closed.
- Use explosion-proof [electrical/ventilating/lighting/…] equipment.
- Use only non-sparking tools.
- Wash … thoroughly after handling.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF IN EYES:
- Get medical advice/attention.
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Store in a well-ventilated place.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 5-Methyl-3-heptanone in the GHS label constructor →
07 · Health hazards
5-Methyl-3-heptanone health hazards and exposure limits
5-Methyl-3-heptanone hazard summary
Narcosis induced in animal inhalation studies. Animals fed 820 mg/kg/day develop evidence of peripheral neuropathy. [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
5-Methyl-3-heptanone occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | 25.0 [ppm] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| PEL | TWA 25 ppm (130 mg/m3) | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | TWA 25 ppm (130 mg/m3) | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | 100 ppm [From NPG: 5-Methyl-3-heptanone] (NIOSH, 2024) | CAMEO Chemicals |
| IDLH | 100.0 [ppm] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| IDLH | 100 ppm | The National Institute for Occupational Safety and Health (NIOSH) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
5-Methyl-3-heptanone properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
5-Methyl-3-heptanone boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 157.22 °C (315 °F) | NIOSH | |
| 157.22 °C (315 °F) | at 760 mmHg | CAMEO | |
| 168 °C (334.4 °F) | at 760 mmHg | DOE PAC |
5-Methyl-3-heptanone melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -56.67 °C (-70 °F) | NIOSH | |
| -56.7 °C (-70.1 °F) | ICSC |
5-Methyl-3-heptanone density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 0.82 g/cm³ | NIOSH |
5-Methyl-3-heptanone solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Insoluble | NIOSH | |
| Insoluble (NIOSH, 2024) | CAMEO | ||
| Solubility in water, g/100ml at 20 °C: 0.3 | at 20 °C | ICSC |
5-Methyl-3-heptanone vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 2 mmHg | NIOSH | |
| 2.0027 mmHg | at 25 °C | ICSC |
5-Methyl-3-heptanone flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 58.89 °C (138 °F) | NIOSH | |
| 43 °C (109.4 °F) | ICSC |
5-Methyl-3-heptanone lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Class II Combustible Liquid: Fl.P. at or above 100 °F and below 140 °F. | NIOSH |
5-Methyl-3-heptanone vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 4.4 (air = 1) | ICSC |
5-Methyl-3-heptanone odor threshold
| Property | Value | Conditions | Source |
|---|---|---|---|
| Odor threshold | Odor Threshold Low: 5.9 [ppm] | Haz-Map | |
| Odor threshold from AIHA | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
5-Methyl-3-heptanone storage and handling
5-Methyl-3-heptanone safe storage
Fireproof. Separated from strong oxidants, strong bases and strong reducing agents. Well closed.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
5-Methyl-3-heptanone incompatible materials
Strong oxidizers
Source: The National Institute for Occupational Safety and Health (NIOSH)
5-Methyl-3-heptanone reactivity
Ketones, such as ETHYL SEC-AMYL KETONE, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 5-Methyl-3-heptanone in the storage compatibility matrix →
10 · Questions
5-Methyl-3-heptanone — frequently asked questions
What is the CAS number of 5-Methyl-3-heptanone?
The CAS number of 5-Methyl-3-heptanone is 541-85-5. Its EC number is 208-793-7.
What is the chemical formula of 5-Methyl-3-heptanone?
The molecular formula of 5-Methyl-3-heptanone is C8H16O and its molecular weight is 128.21 g/mol.
What does a 5-Methyl-3-heptanone label have to show?
Under CLP Annex VI the label for 5-Methyl-3-heptanone carries the pictograms Flame and Exclamation mark and the signal word is Warning.
Is 5-Methyl-3-heptanone flammable?
Yes. CLP Annex VI assigns 5-Methyl-3-heptanone H226 — flammable liquid and vapour. The flash point reported for it is 58.89 °C (138 °F) (NIOSH).
Is 5-Methyl-3-heptanone a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 5-Methyl-3-heptanone. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the exposure limit for 5-Methyl-3-heptanone?
The US occupational exposure limit reported for 5-Methyl-3-heptanone is 25.0 [ppm] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of 5-Methyl-3-heptanone?
The boiling point reported for 5-Methyl-3-heptanone is 157.22 °C (315 °F) (NIOSH).
What is the melting point of 5-Methyl-3-heptanone?
The melting point reported for 5-Methyl-3-heptanone is -56.67 °C (-70 °F) (NIOSH).
How should 5-Methyl-3-heptanone be stored?
CLP Annex VI assigns 5-Methyl-3-heptanone the storage statement P403.
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