Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Acetone

Acetone is a colorless volatile liquid with a fruity odor.

CAS 67-64-1 C3H6O 58.08 g/mol Danger

Acetone Safety Data Sheet →

01 · Identification

What Acetone is

Acetone is a colorless volatile liquid with a fruity odor. Its molecular formula is C3H6O and its molecular weight is 58.08 g/mol. It boils at 56.1 °C, melts at -94.9 °C, is miscible with water.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.

02 · Identifiers

Acetone identifiers and molecular data

Acetone CAS number and EC number

CAS number67-64-1
EC number200-662-2
Index number (CLP Annex VI)606-001-00-8

Acetone molecular formula and molecular weight

Molecular formulaC3H6O
Molecular weight58.08 g/mol
Chemical class Flammable agents - 3rd degree

Other names for Acetone

  • propanone
  • dimethyl ketone
  • 2-propanone
  • Beta-Ketopropane
  • Dimethylformaldehyde
  • Dimethylketal
  • Ketone Propane
  • Ketone, Dimethyl
  • Methyl Ketone
  • Pyroacetic Acid
  • Pyroacetic Ether
  • Chevron Acetone
  • propan-2-one

03 · GHS classification

Acetone hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Acetone pictograms and signal word

Signal wordDanger

Acetone hazard class and category

GHS hazard classes Acetone falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 2 H225 GHS02
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Specific target organ toxicity - single exposure GHS chapter 3.8 Category 3 narcotic H336 GHS07

Acetone hazard statements (H-codes)

Hazard statements assigned to Acetone
CodeHazard statement
H225 Highly flammable liquid and vapour.
H336 May cause drowsiness or dizziness.
H319 Causes serious eye irritation.

Acetone supplemental EU statements (EUH)

EU-specific statements assigned to Acetone. They exist only in CLP and have no counterpart in UN GHS.
CodeStatement
EUH066 Repeated exposure may cause skin dryness or cracking.

This page lists only the codes assigned to Acetone. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Acetone

Our own Acetone safety data sheet walks through all sixteen sections of the published data. What it is not is the document an inspector asks for: an SDS is issued for a product by its supplier, so the sheet covering the grade actually standing in your store exists only in that supplier’s version. Collecting those and keeping them current as suppliers revise them is a separate job.

04 · Precautionary statements

Acetone precautionary statements

CLP Annex VI assigns 11 precautionary statements to Acetone. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Acetone name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български ацетон пропан-2-онпропанон
Spanish español Acetona propan-2-onapropanona
Czech čeština aceton propan-2-onpropanon
Danish dansk acetone propan-2-onpropanon
German Deutsch Aceton Propan-2-onPropanon
Estonian eesti atsetoon propaan-2-oonpropanoon
Greek ελληνικά ακετόνη προπαν-2-όνηπροπανόνη
English English acetone propan-2-onepropanone
French français acétone propan-2-onepropanone
Croatian hrvatski aceton propan-2-onpropanon
Italian italiano acetone 2-propanonepropanone
Latvian latviešu acetons propān-2-onspropanons
Lithuanian lietuvių acetonas propan-2-onaspropanonas
Hungarian magyar aceton propan-2-onpropanon
Maltese Malti aċetun propan-2-onpropanon
Dutch Nederlands aceton propaan-2-onpropanon
Polish polski aceton propan-2-onpropanonketon dimetylowy
Portuguese português acetona propan-2-onapropanona
Romanian română acetonă propan-2-onăpropanonă
Slovak slovenčina acetón propán-2-ónpropanón
Slovenian slovenščina aceton propan-2-onpropanon
Finnish suomi asetoni propan-2-onipropanoni
Swedish svenska aceton propan-2-onpropanon

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Acetone GHS label elements

Everything CLP Annex VI fixes for Acetone, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS07 Exclamation mark pictogram

Danger

Acetone

  • Highly flammable liquid and vapour.
  • May cause drowsiness or dizziness.
  • Causes serious eye irritation.
  • Repeated exposure may cause skin dryness or cracking.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Wash thoroughly after handling.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF IN EYES:
  • Get medical advice/attention.
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Acetone in the GHS label constructor →

07 · Health hazards

Acetone health hazards and exposure limits

Acetone hazard summary

Acetone is a manufactured chemical that is also found naturally in the environment. It is a colorless liquid with a distinct smell and taste. It evaporates easily, is flammable, and dissolves in water. It is also called dimethyl ketone, 2-propanone, and beta-ketopropane. Acetone is used to make plastic, fibers, drugs, and other chemicals. It is also used to dissolve other substances. It occurs naturally in plants, trees, volcanic gases, forest fires, and as a product of the breakdown of body fat. It is present in vehicle exhaust, tobacco smoke, and landfill sites. Industrial processes contribute more acetone to the environment than natural processes.

Source: Agency for Toxic Substances and Disease Registry (ATSDR)

Acetone carcinogenicity classification

Cancer Classification: Group D Not Classifiable as to Human Carcinogenicity

Source: Hazardous Substances Data Bank (HSDB)

CLASSIFICATION: D; not classifiable as to human carcinogenicity. BASIS FOR CLASSIFICATION: Based on lack of data concerning carcinogenicity in humans or animals. HUMAN CARCINOGENICITY DATA: None. ANIMAL CARCINOGENICITY DATA: None.

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

Acetone occupational exposure limits

US occupational exposure limits reported for Acetone. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 1000.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
PEL 1000 ppm (2400 mg/m³) Occupational Safety and Health Administration (OSHA)
PEL TWA 1000 ppm (2400 mg/m3) See Appendix G The National Institute for Occupational Safety and Health (NIOSH)
REL 250 ppm (590 mg/m³) Occupational Safety and Health Administration (OSHA)
REL TWA 250 ppm (590 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
IDLH 2500 ppm ; Based on 10% of the lower explosive limit. (NIOSH, 2024) CAMEO Chemicals
IDLH 2500.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
IDLH 2500 ppm (10% LEL) Occupational Safety and Health Administration (OSHA)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Acetone properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Acetone boiling point

Property Value Conditions Source
Boiling point 56.08 °C (132.9 °F) HSDB
56.11 °C (133 °F) NIOSH
56.11 °C (133 °F) at 760 mmHg CAMEO

Acetone melting point

Property Value Conditions Source
Melting point -94.9 °C (-138.8 °F) HSDB
-95.56 °C (-140 °F) NIOSH
-93.89 °C (-137 °F) CAMEO

Acetone density

Property Value Conditions Source
Density 0.79 g/cm³ NIOSH
0.7845 g/cm³ at 20 °C HSDB
0.791 g/cm³ at 20 °C CAMEO

Acetone solubility

Property Value Conditions Source
Solubility Miscible with water HSDB
Miscible with benzene HSDB
Miscible with alcohol, dimethylformamide, ether HSDB

Acetone vapor pressure

Property Value Conditions Source
Vapor pressure 180 mmHg NIOSH
180 mmHg at 20 °C CAMEO
231 mmHg at 25 °C HSDB

Acetone flash point

Property Value Conditions Source
Flash point -16.99 °C (1.4 °F) HSDB
-20 °C (-4 °F) Closed cup HSDB
-17.78 °C (0 °F) HSDB

Acetone autoignition temperature

Property Value Conditions Source
Autoignition temperature 465 °C (869 °F) HSDB

Acetone lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 2.5 % by volume HSDB
2.6 % by volume HSDB

Acetone upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 12.8 % by volume HSDB

Acetone vapor density

Property Value Conditions Source
Vapor density 2 (air = 1) HSDB

Acetone odor threshold

Property Value Conditions Source
Odor threshold Water: 20 mg/L (or 20 ppm, w/v); air: 13 uL/L (or 13 ppm, v/v). HSDB
Odor low: 47.5 mg/cu m; Odor high: 1613.9 mg/cu m HSDB
Odor Threshold Low: 3.6 [ppm] Haz-Map

Acetone critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 234.95 °C (454.9 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Acetone fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Acetone fire potential

Highly flammable liquid. Dangerous disaster hazard due to fire and explosion hazard ...

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Acetone storage and handling

Acetone reactive group

CAMEO Chemicals places Acetone in the reactive group Ketones. Compatibility with other chemicals is worked out from the group, not from the individual substance — which is why two substances you have never seen react can still be flagged as a pair that must be separated.

A reactive group is a CAMEO Chemicals (US NOAA) grouping, not a GHS hazard class: it has no code, no category and no legal force. It is what the storage compatibility matrix on this site computes from.

Acetone safe storage

Fireproof. Separated from : see Chemical Dangers. Store in an area without drain or sewer access.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Acetone storage conditions

Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Flammable liquids

Source: Hazardous Substances Data Bank (HSDB)

Acetone incompatible materials

Incompatible materials: Bases, Oxidizing agents, Reducing agents, Acetone reacts violently with phosphorous oxychloride.

Source: Hazardous Substances Data Bank (HSDB)

Acetone reactivity

It was reported that a mixture of ACETONE and chloroform, in a residue bottle, exploded. Since addition of acetone to chloroform in the presence of base will result in a highly exothermic reaction, it is thought that a base was in the bottle [MCA Case History 1661. 1970]. Also, Nitrosyl chloride, sealed in a tube with a residue of acetone in the presence of platinum catalyst, gave an explosive reaction [Chem. Eng. News 35(43):60. 1967]. The reaction of nitrosyl perchlorate and acetone ignites and explodes. Explosions occur with mixtures of nitrosyl perchlorate and primary amine [Ann. Chem. 42:2031. 1909]. Reacts violently with nitric acid. Also causes exothermic reaction when in contact with aldehydes.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Acetone in the storage compatibility matrix →

11 · Transport

Acetone UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Acetone under UN 1090 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
ACETONE 3 F1 II
  • ADR label model 3 — Flammable liquid
3

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 3 is “Flammable liquids” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Acetone 3 II
  • US DOT FLAMMABLE LIQUID label (§172.419)
3

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 3 is “Flammable and combustible liquid” (49 CFR 173.2).

Full UN 1090 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

Acetone — frequently asked questions

What is the CAS number of Acetone?

The CAS number of Acetone is 67-64-1. Its EC number is 200-662-2.

What is the chemical formula of Acetone?

The molecular formula of Acetone is C3H6O and its molecular weight is 58.08 g/mol.

What does a Acetone label have to show?

Under CLP Annex VI the label for Acetone carries the pictograms Flame and Exclamation mark and the signal word is Danger.

Is Acetone flammable?

Yes. CLP Annex VI assigns Acetone H225 — highly flammable liquid and vapour. The flash point reported for it is -16.99 °C (1.4 °F) (HSDB).

Is Acetone a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Acetone. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Acetone?

The US occupational exposure limit reported for Acetone is 1000.0 [ppm] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Acetone?

The boiling point reported for Acetone is 56.08 °C (132.9 °F) (HSDB).

What is the melting point of Acetone?

The melting point reported for Acetone is -94.9 °C (-138.8 °F) (HSDB).

How should Acetone be stored?

CLP Annex VI assigns Acetone the storage statement P403. Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Flammable liquids (Hazardous Substances Data Bank (HSDB))

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