Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Carbofuran

Carbofuran is a white, crystalline solid and is odorless.

CAS 1563-66-2 C12H15NO3 221.25 g/mol Danger

01 · Identification

What Carbofuran is

Carbofuran is a white, crystalline solid and is odorless. Its molecular formula is C12H15NO3 and its molecular weight is 221.25 g/mol. It melts at 153 °C.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Carbofuran identifiers and molecular data

Carbofuran CAS number and EC number

CAS number1563-66-2
EC number216-353-0
Index number (CLP Annex VI)006-026-00-9

Carbofuran molecular formula and molecular weight

Molecular formulaC12H15NO3
Molecular weight221.25 g/mol

Other names for Carbofuran

  • carbofuran (ISO)
  • 2,3-dihydro-2,2-dimethylbenzofuran-7-yl N-methylcarbamate

03 · GHS classification

Carbofuran hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Carbofuran pictograms and signal word

Signal wordDanger

Carbofuran hazard class and category

GHS hazard classes Carbofuran falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 1 or 2 H300 GHS06
Acute toxicity - inhalation GHS chapter 3.1 Category 1 or 2 H330 GHS06
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Carbofuran hazard statements (H-codes)

Hazard statements assigned to Carbofuran
CodeHazard statement
H330 Fatal if inhaled.
H300 Fatal if swallowed.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Carbofuran. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Carbofuran

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Carbofuran issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Carbofuran precautionary statements

CLP Annex VI assigns 10 precautionary statements to Carbofuran. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Carbofuran name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български карбофуран (ISO) 2,2-диметил-2,3-дихидробензофуран-7-илов N -метилкарбамат
Spanish español Carbofurán (ISO) N -metilcarbamato de 2,3-dihidro-2,2-dimetilbenzofuran-7-ilo
Czech čeština karbofuran (ISO) 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl- N -methylkarbamát
Danish dansk carbofuran (ISO) 2,3-dihydro-2,2-dimethylbenzofuran-7-ylmethylcarbamat
German Deutsch Carbofuran (ISO) 2,3-Dihydro-2,2-dimethylbenzofuran-7-ylmethylcarbamat
Estonian eesti karbofuraan (ISO) 2,3-dihüdro-2,2-dimetüülbensofuraan-7-üül- N -metüülkarbamaat
Greek ελληνικά carbofuran (καρβοφουράνιο) (ISO) N -μεθυλοκαρβαμιδικός 2,3-διυδρο-2,2-διμεθυλοβενζοφουραν-7-υλεστέρας
English English carbofuran (ISO) 2,3-dihydro-2,2-dimethylbenzofuran-7-yl N -methylcarbamate
French français carbofuran (ISO) N -méthylcarbamate de 2,3-dihydro-2,2-diméthylbenzofuran-7-yle
Croatian hrvatski karbofuran (ISO) 2,3-dihidro-2,2-dimetilbenzofuran-7-il- N -metil-karbamat
Italian italiano carbofuran (ISO) metilcarbammato di 2,3-diidro-2,2-dimetilbenzofuran-7-ile
Latvian latviešu karbofurāns (ISO) 2,3-dihidro-2,2-dimetilbenzfurān-7-il- N -metilkarbamāts
Lithuanian lietuvių karbofuranas (ISO) 2,3-dihidro-2,2-dimetilbenzofuran-7-il N -metilkarbamatas
Hungarian magyar karbofurán (ISO) 2,3-dihidro-2,2-dimetilbenzo-furán-7-il- N -metilkarbamát
Maltese Malti karbofuran (ISO) N-metilkarbamat ta’ 2,3-diidro-2,2-dimetilbenżofuran-7-il
Dutch Nederlands carbofuran (ISO) 2,3-dihydro-2,2-dimethylbenzofuran-7-yl- N -methylcarbamaat
Polish polski karbofuran (ISO) metylokarbaminian 2,2-dimetylo-2,3-dihydrobenzofuran-7-ylu
Portuguese português carbofurão (ISO) N -metilcarbamato de 2,3-di-hidro-2,2-dimetilbenzofuran-7-ilo
Romanian română carbofuran (ISO) N -metilcarbamat de 2,3-dihidro-2,2-dimetilbenzofuran-7-il
Slovak slovenčina karbofurán (ISO) O -(2,2-dimetyl-2,3-dihydrobenzofurán-7-yl)- N -metylkarbamát
Slovenian slovenščina karbofuran (ISO) 2,3-dihidro-2,2-dimetilbenzofuran-7-il N -metilkarbamat
Finnish suomi karbofuraani (ISO) 2,3-dihydro-2,2-dimetyylibentsofuran-7-yyli- N -metyylikarbamaatti
Swedish svenska karbofuran (ISO) 2,3-dihydro-2,2-dimetylbensofuran-7-yl- N -metylkarbamat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Carbofuran GHS label elements

Everything CLP Annex VI fixes for Carbofuran, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS09 Environment pictogram

Danger

Carbofuran

  • Fatal if inhaled.
  • Fatal if swallowed.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Avoid release to the environment.
  • IF SWALLOWED:
  • IF INHALED:
  • Immediately call a POISON CENTER/doctor/
  • Rinse mouth.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Carbofuran in the GHS label constructor →

07 · Health hazards

Carbofuran health hazards and exposure limits

Carbofuran hazard summary

Classified as highly toxic or moderately toxic depending on the formulation, it may be used only by certified applicators. [EXTOXNET] Allergic contact dermatitis in pesticide handlers is most likely due to maneb, carbofuran, carbaryl, captan, folpet, or captafol. [Marks, p. 312] See CARBAMATE INSECTICIDES.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Carbofuran carcinogenicity classification

Cancer Classification: Not Likely to be Carcinogenic to Humans

Source: Hazardous Substances Data Bank (HSDB)

Carbofuran does not appear to possess mutagenic activity and was negative in both rat and mouse oncogenicity assays. Carbofuran is classified as a "Not likely" human carcinogen based on the lack of evidence of carcinogenicity in mice or rats.

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

Carbofuran occupational exposure limits

US occupational exposure limits reported for Carbofuran. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL none See Appendix G The National Institute for Occupational Safety and Health (NIOSH)
REL 0.1 mg/m³ Occupational Safety and Health Administration (OSHA)
REL TWA 0.1 mg/m3 The National Institute for Occupational Safety and Health (NIOSH)
IDLH N.D. The National Institute for Occupational Safety and Health (NIOSH)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Carbofuran properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Carbofuran melting point

Property Value Conditions Source
Melting point 153.2 °C (307.8 °F) HSDB
151.11 °C (304 °F) NIOSH
153 °C (307.4 °F) ICSC

Carbofuran density

Property Value Conditions Source
Density 1.18 g/cm³ HSDB
1.18 g/cm³ at 20 °C CAMEO

Carbofuran solubility

Property Value Conditions Source
Solubility Unstable in alkaline media. Stable in acidic and neutral media. HSDB
In dichloromethane >200, isopropanol 20-50, toluene 10-20 (all in g/L, 20 °C) at 20 °C HSDB
In water, 351 mg/L at 25 °C at 25 °C HSDB

Carbofuran vapor pressure

Property Value Conditions Source
Vapor pressure 540.044 mmHg at 25 °C HSDB
0.000003 mmHg at 25 °C NIOSH

Carbofuran lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) Noncombustible Solid NIOSH

Carbofuran corrosivity

Property Value Conditions Source
Corrosivity Non-corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Carbofuran storage and handling

Carbofuran safe storage

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Carbofuran storage conditions

Separated from food and feedstuffs. Keep in a well-ventilated room.

Source: Hazardous Substances Data Bank (HSDB)

Carbofuran incompatible materials

Alkaline substances, acid, strong oxidizers (e.g., perchlorates, peroxides, chlorates, nitrates, permanganates).

Source: Hazardous Substances Data Bank (HSDB)

Carbofuran reactivity

CARBOFURAN is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates. This compound is unstable in an alkaline media. (NTP, 1992).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Carbofuran in the storage compatibility matrix →

10 · Questions

Carbofuran — frequently asked questions

What is the CAS number of Carbofuran?

The CAS number of Carbofuran is 1563-66-2. Its EC number is 216-353-0.

What is the chemical formula of Carbofuran?

The molecular formula of Carbofuran is C12H15NO3 and its molecular weight is 221.25 g/mol.

What does a Carbofuran label have to show?

Under CLP Annex VI the label for Carbofuran carries the pictograms Skull and crossbones and Environment and the signal word is Danger.

Is Carbofuran flammable?

CLP Annex VI assigns Carbofuran no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Carbofuran a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Carbofuran. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Carbofuran?

The US occupational exposure limit reported for Carbofuran is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the melting point of Carbofuran?

The melting point reported for Carbofuran is 153.2 °C (307.8 °F) (HSDB).

How should Carbofuran be stored?

Separated from food and feedstuffs. Keep in a well-ventilated room. (Hazardous Substances Data Bank (HSDB))

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