Substance profile
Chlorobenzilate
Chlorobenzilate is a colorless solid (pure).
01 · Identification
What Chlorobenzilate is
Chlorobenzilate is a colorless solid (pure). Its molecular formula is C16H14Cl2O3 and its molecular weight is 325.2 g/mol. It melts at 37 °C, is soluble in water.
Under the GHS it carries the signal word Warning. It is classed as hazardous Air Pollutants (HAPs).
02 · Identifiers
Chlorobenzilate identifiers and molecular data
Chlorobenzilate CAS number and EC number
Chlorobenzilate molecular formula and molecular weight
Other names for Chlorobenzilate
- chlorobenzilate (ISO)
- ethyl 2,2-di(4-chlorophenyl)-2-hydroxyacetate
- ethyl 4,4'-dichlorobenzilate
03 · GHS classification
Chlorobenzilate hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Chlorobenzilate pictograms and signal word
Chlorobenzilate hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Chlorobenzilate hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H302 | Harmful if swallowed. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Chlorobenzilate. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Chlorobenzilate
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Chlorobenzilate issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Chlorobenzilate precautionary statements
CLP Annex VI assigns 7 precautionary statements to Chlorobenzilate. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Chlorobenzilate name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | хлоробензилат (ISO) етилов 2,2-ди(4-хлорофенил)-2-хидроксиацетатетилов 4,4′-дихлоробензилат |
| Spanish español | Clorobencilato (ISO) 2,2-di(4-clorofenil)-2-hidroxiacetato de etilo4,4'-diclorobencilato de etilo |
| Czech čeština | chlorbenzilát (ISO) ethyl-2,2- bis (4-chlorfenyl)-2-hydroxyacetátethyl-4,4'-dichlorbenzilát |
| Danish dansk | chlorobenzilat (ISO) ethyl 2,2-di(4-chlorphenyl)-2-hydroxyacetatethyl-4,4'-dichlorbenzilat |
| German Deutsch | Chlorobenzilat (ISO) Ethyl-4,4'-dichlorbenzilatEthyl-2,2-di(4-chlorphenyl)-2-hydroxyacetat |
| Estonian eesti | klorobensülaat (ISO) etüül-2,2-di(4-klorofenüül)-2-hüdroksüatsetaatetüül-4,4'-diklorobensülaat |
| Greek ελληνικά | chlorobenzilate (χλωροβενζιλάτη) (ISO) 2,2-δι(4-χλωροφαινυλο)-2-υδροξυοξικό αιθύλιο4,4′-διχλωροβενζιλικό αιθύλιο |
| English English | chlorobenzilate (ISO) ethyl 2,2-di(4-chlorophenyl)-2-hydroxyacetateethyl 4,4'-dichlorobenzilate |
| French français | chlorobenzilate (ISO) 2,2-di(4-chlorophényl)-2-hydroxyacétate d'éthyle 4,4'-dichlorobenzilate d'éthyle |
| Croatian hrvatski | klorobenzilat (ISO) etil-2,2-di(4-klorfenil)-2-hidroksiacetatetil-4,4'-diklorbenzilat |
| Italian italiano | clorobenzilato (ISO) etil 2,2-di(4-clorofenil)-2-idrossiacetato4,4'-diclorobenzilato di etile |
| Latvian latviešu | hlorbenzilāts (ISO) etil-2,2-di(4-hlorfenil)-2-hidroksiacetātsetil-4,4′-dihlorbenzilāts |
| Lithuanian lietuvių | chlorbenzilatas (ISO) etil 2,2-di(4-chlorfenil)-2-hidroksiacetatasetil-4,4’-dichlorbenzilatas |
| Hungarian magyar | klórbenzilát (ISO) etil-2,2-di(4-klórfenil)-2-hidroxiacetátetil-4,4'-diklórbenzilát |
| Maltese Malti | klorobenżilat (ISO) 2,2-di(4-klorofenil)-2-idrossiaċetat tal-etil4,4'-diklorobenżilat tal-etil |
| Dutch Nederlands | chloorbenzilaat (ISO) ethyl-2,2-di(4-chloorfenyl)-2-hydroxyacetaatethyl-4,4'-dichloorbenzilaat |
| Polish polski | chlorobenzylat (ISO) bis(4-chlorofenylo)hydroksyoctan etylu4,4'-dichlorobenzilan etylu |
| Portuguese português | chlorbenzilato (ISO) 2,2-di(4-clorofenil)-2-hidroxiacetato de etilo4,4'-diclorobenzilato de etilo |
| Romanian română | clorobenzilat (ISO) etil 2,2-di(4-clorofenil)-2-hidroxiacetat4,4'-diclorobenzilat de etil |
| Slovak slovenčina | chlórbenzilát (ISO) O -etyl-2-hydroxy-2,2-bis(4-chlórfenyl)acetátO -etyl-4,4'-dichlórbenzilát |
| Slovenian slovenščina | klorobenzilat (ISO) etil 2,2-di(4-klorofenil)-2-hidroksiacetatetil 4,4'-diklorobenzilat |
| Finnish suomi | klooribentsilaatti (ISO) etyyli-2,2-di(4-kloorifenyyli)-2-hydroksiasetaattietyyli-4,4'-diklooribentsilaatti |
| Swedish svenska | klorbensilat (ISO) etyl-2,2-di(4-klorfenyl)-2-hydroxiacetatetyl-4,4'-diklorbensilat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Chlorobenzilate GHS label elements
Everything CLP Annex VI fixes for Chlorobenzilate, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Chlorobenzilate
- Harmful if swallowed.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- IF SWALLOWED:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Rinse mouth.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Chlorobenzilate in the GHS label constructor →
07 · Health hazards
Chlorobenzilate health hazards and exposure limits
Chlorobenzilate hazard summary
Until 1999, chlorobenzilate was used as a pesticide in citrus and deciduous fruit trees. Limited information is available on the acute (short-term) or chronic (long-term) effects of chlorobenzilate in humans. No inhalation data are available. Poor appetites, anemia, cardiac changes, and effects on the liver, spleen, and bone marrow were observed in dogs chronically exposed to high levels of chlorobenzilate by ingestion. No information is available on the carcinogenic effects of chlorobenzilate in humans. Chlorobenzilate has been found to be carcinogenic in orally exposed mice, with increased incidences of liver tumors observed. EPA has classified chlorobenzilate as a Group B2, probable human carcinogen.
Source: EPA Hazardous Air Pollutants
Chlorobenzilate carcinogenicity classification
Under the conditions of this bioassay, orally administered chlorobenzilate was carcinogenic in male and female B6C3F1 mice, causing an increased incidence of hepatocellular carcinomas. The results do not, however, provide sufficient evidence for the carcinogenicity of chlorobenzilate in Osborne-Mendel rats.
Source: US National Toxicology Program · TR-075: Bioassay of Chlorobenzilate for Possible Carcinogenicity (CASRN 510-15-6) (1978 )
The Carcinogen Assessment Group in EPA's Research and Development Office has evaluated ethyl 4,4-dichlorobenzilate for carcinogenicity. According to their analysis, the weight of evidence for ethyl 4,4-dichlorobenzilate is group B2, which is based on inadequate evidence in humans and sufficient evidence in animals. As a group B2 chemical, ethyl 4,4-dichlorobenzilate is considered a probable human carcinogen.
Source: Hazardous Substances Data Bank (HSDB)
No data are available in humans. Limited evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 3: The agent is not classifiable as to its carcinogenicity to humans.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Chlorobenzilate properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Chlorobenzilate boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 147 °C (296.6 °F) | range, midpoint shown, at 0.04 mmHg (reduced pressure) | HSDB |
| 156.94 °C (314.5 °F) | range, midpoint shown, at 0.07 mmHg (reduced pressure) | CAMEO |
Chlorobenzilate melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 37 °C (98.6 °F) | ICSC | |
| 36.75 °C (98.2 °F) | range, midpoint shown | HSDB |
Chlorobenzilate density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.28 g/cm³ | ICSC | |
| 1.2816 g/cm³ | at 20 °C, Technical grade | HSDB | |
| 1.2816 g/cm³ | at 20 °C | CAMEO |
Chlorobenzilate solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Soluble in most organic solvents | HSDB | |
| Soluble in most organic solvents, including petroleum oils | Technical | HSDB | |
| Solubility at 20 °C: 1 g/kg acetone, dichloromethane, and methanol; 1000 g/kg toluene; 600 g/kg hexane; 700 g/kg 1-octanol | at 20 °C | HSDB |
Chlorobenzilate vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.0000022 mmHg | at 20 °C | HSDB |
| 0.0000022 mmHg | Haz-Map |
Chlorobenzilate lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Containers may explode in fire ... Storage containers may rocket great distances, in many directions ... | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Chlorobenzilate fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Chlorobenzilate fire potential
This chemical may burn but does not easily ignite.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Chlorobenzilate storage and handling
Chlorobenzilate safe storage
Separated from food and feedstuffs, strong oxidants, bases and strong acids.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Chlorobenzilate storage conditions
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practicable to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/
Source: Hazardous Substances Data Bank (HSDB)
Chlorobenzilate incompatible materials
Strong acids , strong bases, lime.
Source: Hazardous Substances Data Bank (HSDB)
Chlorobenzilate reactivity
CHLOROBENZILATE is hydrolyzed by alkalis and strong acids. Incompatible with lime (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Chlorobenzilate in the storage compatibility matrix →
11 · Questions
Chlorobenzilate — frequently asked questions
What is the CAS number of Chlorobenzilate?
The CAS number of Chlorobenzilate is 510-15-6. Its EC number is 208-110-2.
What is the chemical formula of Chlorobenzilate?
The molecular formula of Chlorobenzilate is C16H14Cl2O3 and its molecular weight is 325.2 g/mol.
What does a Chlorobenzilate label have to show?
Under CLP Annex VI the label for Chlorobenzilate carries the pictograms Exclamation mark and Environment and the signal word is Warning.
Is Chlorobenzilate flammable?
CLP Annex VI assigns Chlorobenzilate no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Chlorobenzilate a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Chlorobenzilate. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.
What is the boiling point of Chlorobenzilate?
The boiling point reported for Chlorobenzilate is 147 °C (296.6 °F), range, midpoint shown, at 0.04 mmHg (reduced pressure) (HSDB).
What is the melting point of Chlorobenzilate?
The melting point reported for Chlorobenzilate is 37 °C (98.6 °F) (ICSC).
How should Chlorobenzilate be stored?
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practicable to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/ (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Chlorobenzilate
Keep going: substances starting with C, or search the whole database by name, CAS number, pictogram or signal word.