Substance profile
Chlorpyrifos-methyl
Chlorpyrifos-methyl is white crystals with a slight mercaptan odor.
01 · Identification
What Chlorpyrifos-methyl is
Chlorpyrifos-methyl is white crystals with a slight mercaptan odor. Its molecular formula is C7H7Cl3NO3PS and its molecular weight is 322.5 g/mol. It melts at 46 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
Chlorpyrifos-methyl identifiers and molecular data
Chlorpyrifos-methyl CAS number and EC number
Chlorpyrifos-methyl molecular formula and molecular weight
Other names for Chlorpyrifos-methyl
- chlorpyrifos-methyl (ISO),
- O, O-dimethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate
03 · GHS classification
Chlorpyrifos-methyl hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Chlorpyrifos-methyl pictograms and signal word
Chlorpyrifos-methyl hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Chlorpyrifos-methyl hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Chlorpyrifos-methyl. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Chlorpyrifos-methyl
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Chlorpyrifos-methyl issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Chlorpyrifos-methyl precautionary statements
CLP Annex VI assigns 8 precautionary statements to Chlorpyrifos-methyl. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Chlorpyrifos-methyl name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | хлорпирифос-метил (ISO) O , O -диметилов O -3,5,6-трихлоро-2-пиридилов фосфоротиоат |
| Spanish español | Clorpirifós-metilo (ISO) fosforotioato de O, O -dimetilo y O -3,5,6-tricloro-2-piridilo |
| Czech čeština | chlorpyrifos-methyl (ISO) O, O -dimethyl- O -3,5,6-trichlor-2-pyridyl-fosforothioát |
| Danish dansk | chlorpyrifos-methyl (ISO) O, O- dimethyl O- 3,5,6-trichlor-2-pyridylthiophosphat |
| German Deutsch | Chlorpyrifos-methyl (ISO) O, O -Dimethyl- O -3,5,6-trichlor- 2-pyridylphosphorothioat |
| Estonian eesti | kloorpürifoss-metüül (ISO) O, O -dimetüül- O -3,5,6-trikloro-2-püridüülfosforotioaat |
| Greek ελληνικά | chlorpyrifos-methyl (μεθυλικό χλωροπυριφός) (ISO) θειοφωσφορικό O, O -διμεθύλιο O -3,5,6-τριχλωρο-2-πυριδύλιο |
| English English | chlorpyrifos-methyl (ISO) O, O -dimethyl O -3,5,6-trichloro-2-pyridyl phosphorothioate |
| French français | chlorpyrifos-méthyl (ISO) phosphorothioate de O, O -diméthyle et de O -3,5,6-trichloro-2-pyridyle |
| Croatian hrvatski | klorpirifos-metil (ISO) O, O -dimetil- O -3,5,6-triklor-2-piridil-fosforotioat |
| Italian italiano | Clorpirifos- metile (ISO) tiofosfato di O, O -dimetil e di O -3,5,6-tricloro-2-piridile |
| Latvian latviešu | hlorpirifos-metila (ISO) O, O -dimetil- O -3,5,6-trihlor-2-piridilfosfortioāts |
| Lithuanian lietuvių | metilchlorpirifosas (ISO) O, O -dimetil- O -3,5,6-trichlor-2-piridiltiofosfatas |
| Hungarian magyar | klórpirifosz-metil (ISO) O, O -dimetil- O -3,5,6-triklór-2-piridil-tiofoszfát |
| Maltese Malti | klorpirifos-metil (ISO) fosforotijoat O, O -dimetil O -3,5,6-trikloro-2-piridil |
| Dutch Nederlands | chloorpyrifos-methyl (ISO) O, O -dimethyl- O -3,5,6-trichloor-2-pyridylthiofosfaat |
| Polish polski | chloropiryfos metylowy (ISO) tiofosforan O -3,5,6-trichloro-2-pirydylu- O, O -dimetylu |
| Portuguese português | clorpirifos-metilo (ISO) tiofosfato de O , O -dimetilo e de O -3,5,6-tricloro-2-piridilo |
| Romanian română | clorpirifos- metil (ISO) tiofosfat de O, O -dimetil și de O -3,5,6-tricloro-2-piridil |
| Slovak slovenčina | chlórpyrifos-metyl (ISO) O, O -dimetyl- O -(3,5,6-trichlór-2-pyridyl)- fosforotioát |
| Slovenian slovenščina | klorpirifos-metil (ISO) O, O -dimetil O -3,5,6-trikloro-2-piridil fosforotioat |
| Finnish suomi | klorpyrifossimetyyli (ISO) O, O -dimetyyli- O -3,5,6-trikloori-2-pyridyylifosforotioaatti |
| Swedish svenska | klorpyrifosmetyl (ISO) O, O -dimetyl- O -3,5,6-triklor-2-pyridylfosfortioat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Chlorpyrifos-methyl GHS label elements
Everything CLP Annex VI fixes for Chlorpyrifos-methyl, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Chlorpyrifos-methyl
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- Get medical advice/attention.
- If skin irritation or rash occurs:
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Chlorpyrifos-methyl in the GHS label constructor →
07 · Health hazards
Chlorpyrifos-methyl health hazards and exposure limits
Chlorpyrifos-methyl hazard summary
A skin irritant; [SAX] May cause skin sensitization; [eChemPortal: ESIS] In a two year feeding study with rats (highest dose level 1 mg/kg/day) no significant adverse gross or histopathological changes were observed as well as no relation to frequency of spontaneous tumors; Effects in a three generation feeding study with rats include inhibition of cholinesterase activity and decreased pup weights in the second and third generation; No significant effects were observed in fertility, gestation, viability, or lactation; No gross or histopathological changes were noted in third generation parental animals; No teratogenic effects observed in a study with rats; [Reference #2] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs] See Chlorpyrifos.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Chlorpyrifos-methyl properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Chlorpyrifos-methyl melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 46 °C (114.8 °F) | range, midpoint shown | HSDB |
Chlorpyrifos-methyl density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.64 g/cm³ | at 23 °C | HSDB |
Chlorpyrifos-methyl solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | In water, 4.76 mg/L at 20 °C | at 20 °C | HSDB |
| In acetone > 400; methanol 190; hexane 120 (all in g/kg at 20 °C) | at 20 °C | HSDB | |
| In water, 4.0 mg/L at 25 °C | at 25 °C | HSDB |
Chlorpyrifos-methyl vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 22500 mmHg | at 25 °C | HSDB |
| 0.0000422 mmHg | Haz-Map |
Chlorpyrifos-methyl flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 182 °C (359.6 °F) | Cleveland open cup | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Chlorpyrifos-methyl storage and handling
Chlorpyrifos-methyl storage conditions
Do not contaminate water, food or feed by storage ... Store in a cool, dry location. Do not store in direct sunlight. Do not use or store near heat or open flame. /Storcide II Grain, Bin and Warehouse Insecticide/
Source: Hazardous Substances Data Bank (HSDB)
Chlorpyrifos-methyl incompatible materials
Incompatible with alkaline & strongly acidic materials.
Source: Hazardous Substances Data Bank (HSDB)
Chlorpyrifos-methyl reactivity
A chlorinated organophosphate derivative. Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. It is incompatible with strong acids and bases.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Chlorpyrifos-methyl in the storage compatibility matrix →
10 · Questions
Chlorpyrifos-methyl — frequently asked questions
What is the CAS number of Chlorpyrifos-methyl?
The CAS number of Chlorpyrifos-methyl is 5598-13-0. Its EC number is 227-011-5.
What is the chemical formula of Chlorpyrifos-methyl?
The molecular formula of Chlorpyrifos-methyl is C7H7Cl3NO3PS and its molecular weight is 322.5 g/mol.
What does a Chlorpyrifos-methyl label have to show?
Under CLP Annex VI the label for Chlorpyrifos-methyl carries the pictograms Exclamation mark and Environment and the signal word is Warning.
Is Chlorpyrifos-methyl flammable?
CLP Annex VI assigns Chlorpyrifos-methyl no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 182 °C (359.6 °F), Cleveland open cup (HSDB).
Is Chlorpyrifos-methyl a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Chlorpyrifos-methyl. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the melting point of Chlorpyrifos-methyl?
The melting point reported for Chlorpyrifos-methyl is 46 °C (114.8 °F), range, midpoint shown (HSDB).
How should Chlorpyrifos-methyl be stored?
Do not contaminate water, food or feed by storage ... Store in a cool, dry location. Do not store in direct sunlight. Do not use or store near heat or open flame. /Storcide II Grain, Bin and Warehouse Insecticide/ (Hazardous Substances Data Bank (HSDB))
Nearby
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