Substance profile
Colecalciferol
Colecalciferol is fine needles from dilute acetone and is odorless.
01 · Identification
What Colecalciferol is
Colecalciferol is fine needles from dilute acetone and is odorless. Its molecular formula is C27H44O and its molecular weight is 384.6 g/mol. It melts at 84.5 °C, is practically insoluble in water.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Colecalciferol identifiers and molecular data
Colecalciferol CAS number and EC number
Colecalciferol molecular formula and molecular weight
Other names for Colecalciferol
- cholecalciferol
- Vitamin D3
03 · GHS classification
Colecalciferol hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Colecalciferol pictograms and signal word
Colecalciferol hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 1 or 2 | H310 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 1 or 2 | H330 | GHS06 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 1 | H372 | GHS08 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Colecalciferol hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H330 | Fatal if inhaled. |
| H310 | Fatal in contact with skin. |
| H300 | Fatal if swallowed. |
| H372 | Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
This page lists only the codes assigned to Colecalciferol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Colecalciferol
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Colecalciferol issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Colecalciferol precautionary statements
CLP Annex VI assigns 11 precautionary statements to Colecalciferol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Colecalciferol name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | колекалциферол холекалциферолвитамин D3 |
| Spanish español | Colecalciferol vitamina D 3 |
| Czech čeština | cholekalciferol vitamin D 3 |
| Danish dansk | colecalciferol cholecalciferolvitamin D3 |
| German Deutsch | Colecalciferol CholecalciferolVitamin D3 |
| Estonian eesti | kolekaltsiferool D3-vitamiin |
| Greek ελληνικά | χοληκαλσιφερόλη βιταμίνη D3 |
| English English | colecalciferol cholecalciferolvitamin D 3 |
| French français | colécalciférol cholécalciférolvitamine D 3 |
| Croatian hrvatski | kolekalciferol vitamin D3 |
| Italian italiano | colecalciferolo vitamina D3 |
| Latvian latviešu | kolekalciferols holekalciferolsD3 vitamīns |
| Lithuanian lietuvių | kolekalciferolis cholekalciferolisvitaminas D3 |
| Hungarian magyar | kolekalciferol D3-vitamin |
| Maltese Malti | kolekalċiferol vitamina D 3 |
| Dutch Nederlands | colecalciferol cholecalciferolvitamine D3 |
| Polish polski | kolekalcyferol cholekalcyferolwitamina D3 |
| Portuguese português | colecalciferol vitamina D3 |
| Romanian română | colecalciferol vitamina D3 |
| Slovak slovenčina | kolekalciferol cholekalciferol vitamín D3 |
| Slovenian slovenščina | holekalciferol vitamin D3 |
| Finnish suomi | kolekalsiferoli D3-vitamiini |
| Swedish svenska | kolekalciferol vitamin D3 |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Colecalciferol GHS label elements
Everything CLP Annex VI fixes for Colecalciferol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Colecalciferol
- Fatal if inhaled.
- Fatal in contact with skin.
- Fatal if swallowed.
- Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Colecalciferol in the GHS label constructor →
07 · Health hazards
Colecalciferol health hazards and exposure limits
Colecalciferol hazard summary
May cause irritation; Highly toxic by ingestion and skin absorption; Toxic by inhalation; Prolonged or repeated ingestion exposure may cause organ injury; Targets the kidney and heart; May cause reproductive toxicity and teratogenicity; [Sigma-Aldrich MSDS] See Vitamin D.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Colecalciferol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Colecalciferol melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 84.5 °C (184.1 °F) | range, midpoint shown | HSDB |
| 84.44 °C (184 °F) | range, midpoint shown | CAMEO | |
| 84.5 °C (184.1 °F) | HMDB |
Colecalciferol solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Sol in the usual org solvents; slightly sol in vegetable oils | HSDB | |
| Insoluble (NTP, 1992) | CAMEO | ||
| Insoluble | DrugBank |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Colecalciferol storage and handling
Colecalciferol reactivity
VITAMIN D3 may react vigorously with strong oxidizing agents. May react exothermically with reducing agents to release hydrogen gas.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Colecalciferol in the storage compatibility matrix →
10 · Questions
Colecalciferol — frequently asked questions
What is the CAS number of Colecalciferol?
The CAS number of Colecalciferol is 67-97-0. Its EC number is 200-673-2.
What is the chemical formula of Colecalciferol?
The molecular formula of Colecalciferol is C27H44O and its molecular weight is 384.6 g/mol.
What does a Colecalciferol label have to show?
Under CLP Annex VI the label for Colecalciferol carries the pictograms Skull and crossbones and Health hazard and the signal word is Danger.
Is Colecalciferol flammable?
CLP Annex VI assigns Colecalciferol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Colecalciferol a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Colecalciferol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the melting point of Colecalciferol?
The melting point reported for Colecalciferol is 84.5 °C (184.1 °F), range, midpoint shown (HSDB).
Nearby
Substances next to Colecalciferol
Keep going: substances starting with C, or search the whole database by name, CAS number, pictogram or signal word.