Substance profile
Disulfoton
Disulfoton is a pure compound: yellow liquid with a characteristic, sulfur odor.
01 · Identification
What Disulfoton is
Disulfoton is a pure compound: yellow liquid with a characteristic, sulfur odor. Its molecular formula is C8H19O2PS3 and its molecular weight is 274.4 g/mol. It boils at 133 °C, melts at -25 °C, is miscible with water.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Disulfoton identifiers and molecular data
Disulfoton CAS number and EC number
Disulfoton molecular formula and molecular weight
Other names for Disulfoton
- disulfoton (ISO)
- O,O-diethyl 2-ethylthioethyl phosphorodithioate
03 · GHS classification
Disulfoton hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Disulfoton pictograms and signal word
Disulfoton hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 1 or 2 | H310 | GHS06 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Disulfoton hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H310 | Fatal in contact with skin. |
| H300 | Fatal if swallowed. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Disulfoton. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Disulfoton
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Disulfoton issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Disulfoton precautionary statements
CLP Annex VI assigns 10 precautionary statements to Disulfoton. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Disulfoton name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | дисулфотон (ISO) O , O -диетилов 2-етилтиоетилов фосфородитиоат |
| Spanish español | Disulfotón (ISO) fosforoditioato de O , O -dietilo y 2-etiltioetilo |
| Czech čeština | disulfoton (ISO) O, O -diethyl- S -[2-(ethylsulfanyl)ethyl]-fosforodithioát |
| Danish dansk | disulfoton (ISO) O, O- diethyl-2-ethylthioethyldithiophosphat |
| German Deutsch | Disulfoton (ISO) O , O -Diethyl-2-ethylthioethylphosphorodithioat |
| Estonian eesti | disulfotoon (ISO) O , O -dietüül-2-etüültioetüülfosforoditioaat |
| Greek ελληνικά | disulfoton (δισουλφοτόνη) (ISO) διθειοφωσφορικό O , O -διαιθύλιο 2-αιθυλοθειοαιθύλιο |
| English English | disulfoton (ISO) O , O -diethyl 2-ethylthioethyl phosphorodithioate |
| French français | disulfoton (ISO) phosphorodithioate de O , O -diéthyle et de 2-éthylthioéthyle |
| Croatian hrvatski | disulfoton (ISO) O , O -dietil-2-etil-tioetil-fosforoditioat |
| Italian italiano | disulfoton (ISO) ditiofosfato di O, O-dietile e 2-etiltioetile |
| Latvian latviešu | disulfotons (ISO) O , O -dieti-2-etiltioetilfosforditioāts |
| Lithuanian lietuvių | disulfotonas (ISO) O , O -dietil-2-etiltioetilditiofosfatas |
| Hungarian magyar | diszulfoton (ISO) O, O -dietil-2-etiltioetil-ditiofoszfát |
| Maltese Malti | disulfoton (ISO) fosforoditijoat ta’ O , O -dietil 2-etiltijoetil |
| Dutch Nederlands | disulfoton (ISO) O , O -diëthyl-2-ethylthioëthyldithiofosfaat |
| Polish polski | disulfoton (ISO) ditiofosforan O , O -dietylu- S -2-(etylosulfanylo)etylu |
| Portuguese português | dissulfotão (ISO) ditiofosfato de O , O -dietilo e de 2-etiltioetilo |
| Romanian română | disulfoton (ISO) ditiofosfat de O, O -dietil și de 2-etiltioetil |
| Slovak slovenčina | disulfotón (ISO) O, O -dietyl- S -[2-(etylsulfanyl)etyl]- fosforoditioát |
| Slovenian slovenščina | disulfoton (ISO) O , O -dietil 2-etiltioetil fosforoditioat |
| Finnish suomi | disulfotoni (ISO) O , O -dietyyli- S -2-etyylitioetyylifosforoditioaatti |
| Swedish svenska | disulfoton (ISO) O , O -dietyl-2-etyltioetylfosforditioat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Disulfoton GHS label elements
Everything CLP Annex VI fixes for Disulfoton, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Disulfoton
- Fatal in contact with skin.
- Fatal if swallowed.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- Immediately call a POISON CENTER/doctor/…
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Disulfoton in the GHS label constructor →
07 · Health hazards
Disulfoton health hazards and exposure limits
Disulfoton hazard summary
Disulfoton is a manufactured substance used as a pesticide to control a variety of harmful pests that attack many field and vegetable crops. It does not occur naturally. Pure disulfoton is a colorless oil with an unidentifiable characteristic odor and taste. The technical product is dark yellowish, with an aromatic odor. Common trade names are Di-syston, Disystox, Frumin AL, and Soilvirex. Use of trade names is for identification only and does not imply endorsement by the Agency for Toxic Substances and Disease Registry, the Public Health Service, or the U.S. Department of Health and Human Services. It is used to protect small grains, sorghum, corn, and other field crops; some vegetables, fruit, and nut crops; and ornamental and potted plants against certain insects. Although it is used mostly in agriculture, small quantities are used on home and garden plants, and for mosquito control in swamps. The use of disulfoton has decreased in recent years.
Source: Agency for Toxic Substances and Disease Registry (ATSDR)
Disulfoton carcinogenicity classification
Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
Disulfoton occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | none See Appendix G | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | 0.1 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| REL | TWA 0.1 mg/m3 [skin] | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | N.D. | The National Institute for Occupational Safety and Health (NIOSH) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
Disulfoton properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Disulfoton boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 132.5 °C (270.5 °F) | range, midpoint shown | OSHA |
| 62 °C (143.6 °F) | at 0.01 mmHg (reduced pressure) | HSDB | |
| 132.5 °C (270.5 °F) | range, midpoint shown, at 1.5 mmHg (reduced pressure) | HSDB |
Disulfoton melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -25 °C (-13 °F) | HSDB | |
| -25 °C (-13 °F) | above this value | NIOSH |
Disulfoton density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.14 g/cm³ | NIOSH | |
| 1.144 g/cm³ | CAMEO | ||
| 1.144 g/cm³ | at 20 °C | HSDB |
Disulfoton solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | SOL IN MOST ORG LIQ & FATTY OILS | HSDB | |
| Miscible in n-hexane, dichloromethane, 2-propanol, toluene | HSDB | ||
| In water, 16.3 mg/l @ 20 °C | at 20 °C | HSDB |
Disulfoton vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.0002 mmHg | NIOSH | |
| 0.00018 mmHg | at 20 °C | CAMEO | |
| 0.0000975 mmHg | at 25 °C | HSDB |
Disulfoton flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 133 °C (271.4 °F) | HSDB | |
| 82.22 °C (180 °F) | above this value | NIOSH |
Disulfoton lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Combustible Liquid, but will not ignite easily. | NIOSH |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Disulfoton fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Disulfoton fire potential
... Flammable in xylene solution.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Disulfoton storage and handling
Disulfoton safe storage
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Disulfoton storage conditions
Store in original container, preferably in a locked area, away from children, food, feed.
Source: Hazardous Substances Data Bank (HSDB)
Disulfoton incompatible materials
Alkalis.
Source: Hazardous Substances Data Bank (HSDB)
Disulfoton reactivity
DISULFOTON is incompatible with the following: Alkalis (NIOSH, 2024). Organothiophosphates, such as DISULFOTON, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Disulfoton in the storage compatibility matrix →
11 · Questions
Disulfoton — frequently asked questions
What is the CAS number of Disulfoton?
The CAS number of Disulfoton is 298-04-4. Its EC number is 206-054-3.
What is the chemical formula of Disulfoton?
The molecular formula of Disulfoton is C8H19O2PS3 and its molecular weight is 274.4 g/mol.
What does a Disulfoton label have to show?
Under CLP Annex VI the label for Disulfoton carries the pictograms Skull and crossbones and Environment and the signal word is Danger.
Is Disulfoton flammable?
CLP Annex VI assigns Disulfoton no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 133 °C (271.4 °F) (HSDB).
Is Disulfoton a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Disulfoton. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the exposure limit for Disulfoton?
The US occupational exposure limit reported for Disulfoton is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of Disulfoton?
The boiling point reported for Disulfoton is 132.5 °C (270.5 °F), range, midpoint shown (OSHA).
What is the melting point of Disulfoton?
The melting point reported for Disulfoton is -25 °C (-13 °F) (HSDB).
How should Disulfoton be stored?
Store in original container, preferably in a locked area, away from children, food, feed. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Disulfoton
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