Substance profile
Ephedrine
Ephedrine is waxy solid, crystals or granules.
01 · Identification
What Ephedrine is
Ephedrine is waxy solid, crystals or granules. Its molecular formula is C10H15NO and its molecular weight is 165.23 g/mol. It boils at 260 °C, melts at 38.1 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
Ephedrine identifiers and molecular data
Ephedrine CAS number and EC number
Ephedrine molecular formula and molecular weight
03 · GHS classification
Ephedrine hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Ephedrine pictograms and signal word
Ephedrine hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
Ephedrine hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H302 | Harmful if swallowed. |
This page lists only the codes assigned to Ephedrine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Ephedrine
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Ephedrine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Ephedrine precautionary statements
CLP Annex VI assigns 4 precautionary statements to Ephedrine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Ephedrine name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | ефедрин |
| Spanish español | Efedrina |
| Czech čeština | efedrin |
| Danish dansk | ephedrin |
| German Deutsch | Ephedrin L-erythro-2-Methylamino-1-phenyl- propan-1-ol |
| Estonian eesti | efedriin |
| Greek ελληνικά | εφεδρίνη |
| English English | ephedrine |
| French français | éphédrine |
| Croatian hrvatski | efedrin |
| Italian italiano | efedrina |
| Latvian latviešu | efedrīns |
| Lithuanian lietuvių | efedrinas |
| Hungarian magyar | efedrin |
| Maltese Malti | efedrina |
| Dutch Nederlands | efedrine |
| Polish polski | efedryna |
| Portuguese português | efedrina |
| Romanian română | efedrină |
| Slovak slovenčina | efedrín erytro -1-fenyl-2-(metylamino)propán-1-ol |
| Slovenian slovenščina | efedrin |
| Finnish suomi | efedriini |
| Swedish svenska | efedrin |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Ephedrine GHS label elements
Everything CLP Annex VI fixes for Ephedrine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Ephedrine
- Harmful if swallowed.
- Do not eat, drink or smoke when using this product.
- IF SWALLOWED:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Rinse mouth.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Ephedrine in the GHS label constructor →
07 · Physical and chemical properties
Ephedrine properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Ephedrine boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 260 °C (500 °F) | at 745 mmHg | HSDB |
| 255 °C (491 °F) | decomposes, decomposes | HSDB | |
| 255 °C (491 °F) | DrugBank |
Ephedrine melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 38.1 °C (100.6 °F) | HSDB | |
| 34 °C (93.2 °F) | HMDB |
Ephedrine density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.0085 g/cm³ | at 22 °C | HSDB |
Ephedrine solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Soluble in oils | HSDB | |
| Soluble in water, ethanol, ether, benzene and chloroform | HSDB | ||
| In water, 56,900 mg/L at 25 °C ; 63,600 mg/L at 30 °C | at 25 °C | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
08 · Handling and storage
Ephedrine storage and handling
Ephedrine storage conditions
...must be stored in light-resistant containers. Ephedrine base should be stored at or below 8 °C.
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check Ephedrine in the storage compatibility matrix →
09 · Questions
Ephedrine — frequently asked questions
What is the CAS number of Ephedrine?
The CAS number of Ephedrine is 299-42-3. Its EC number is 206-080-5.
What is the chemical formula of Ephedrine?
The molecular formula of Ephedrine is C10H15NO and its molecular weight is 165.23 g/mol.
What does a Ephedrine label have to show?
Under CLP Annex VI the label for Ephedrine carries the pictogram Exclamation mark and the signal word is Warning.
Is Ephedrine flammable?
CLP Annex VI assigns Ephedrine no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Ephedrine a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Ephedrine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Ephedrine?
The boiling point reported for Ephedrine is 260 °C (500 °F), at 745 mmHg (HSDB).
What is the melting point of Ephedrine?
The melting point reported for Ephedrine is 38.1 °C (100.6 °F) (HSDB).
How should Ephedrine be stored?
...must be stored in light-resistant containers. Ephedrine base should be stored at or below 8 °C. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Ephedrine
Keep going: substances starting with E, or search the whole database by name, CAS number, pictogram or signal word.