Substance profile
Endrin
Endrin is a white, crystalline solid and is odorless.
01 · Identification
What Endrin is
Endrin is a white, crystalline solid and is odorless. It boils at 245 °C, melts at 200 °C.
Under the GHS it carries the signal word Danger. It is classed as teratogens.
02 · Identifiers
Endrin identifiers and molecular data
Endrin CAS number and EC number
Endrin molecular formula and molecular weight
Other names for Endrin
- endrin (ISO)
- 1,2,3,4,10,10-hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalene
03 · GHS classification
Endrin hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Endrin pictograms and signal word
Endrin hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 3 | H311 | GHS06 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Endrin hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H300 | Fatal if swallowed. |
| H311 | Toxic in contact with skin. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Endrin. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Endrin
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Endrin issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Endrin precautionary statements
CLP Annex VI assigns 10 precautionary statements to Endrin. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Endrin name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | ендрин (ISO) 1,2,3,4,10,10-хексахлоро-6,7-епокси-1,4,4a,5,6,7,8,8a-октахидро-1,4:5,8-диметанонафтален |
| Spanish español | Endrina (ISO) 1,2,3,4,10,10-hexacloro-6,7-epoxi-1,4,4a,5,6,7,8,8a-octahidro-1,4:5,8-dimetanonaftaleno |
| Czech čeština | endrin (ISO) 1,2,3,4,10,10-hexachlor-6,7-epoxy-1,4,4a,5,6,7,8,8a-oktahydro-1,4:5,8-dimethanonaftalen |
| Danish dansk | endrin (ISO) 1,2,3,4,10,10-hexachlor-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalen |
| German Deutsch | Endrin (ISO) 1,2,3,4,10,10-Hexachlor-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalin |
| Estonian eesti | endriin (ISO) 1,2,3,4,10,10-heksakloro-6,7-epoksü-1,4,4a,5,6,7,8,8a-oktahüdro-1,4:5,8-dimetanonaftaleen |
| Greek ελληνικά | endrin (ενδρίνη) (ISO) 1,2,3,4,10,10-εξαχλωρο-6,7-εποξυ-1,4,4a,5,6,7,8,8a-οκταϋδρο-1,4:5,8-διμεθανοναφθαλίνιο |
| English English | endrin (ISO) 1,2,3,4,10,10-hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalene |
| French français | endrine (ISO) 1,2,3,4,10,10-hexachloro-6,7-époxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-diméthanonaphtalène |
| Croatian hrvatski | endrin (ISO) 1,2,3,4,10,10-heksaklor-6,7-epoksi-1,4,4a,5,6,7,8,8a-oktahidro-1,4:5,8-dimetanonaftalen |
| Italian italiano | endrina (ISO) 1,2,3,4,10,10-esacloro-6,7-epossi-1,4,4a,5,6,7,8,8a-ottaidro-1,4:5,8-dimetanonaftalene |
| Latvian latviešu | endrīns (ISO) 1,2,3,4,10,10-heksahlor-6,7-epoksi-1,4,4a,5,6,7,8,8a-oktahidro-1,4:5,8-dimetanonaftalīns |
| Lithuanian lietuvių | endrinas (ISO) 1,2,3,4,10,10-heksachlor-6,7-epoksi-1,4,4a,5,6,7,8,8a-oktahidro-1,4:5,8-dimetannaftalenas |
| Hungarian magyar | endrin (ISO) 1,2,3,4,10,10-hexaklór-6,7-epoxi-1,4,4a,5,6,7,8,8a-oktahidro-1,4:5,8-dimetanonaftalin |
| Maltese Malti | endrin (ISO) 1,2,3,4,10,10-eżakloro-6,7-epoksi-1,4,4a,5,6,7,8,8a-ottaidro-1,4:5,8-dimetanonaftalen |
| Dutch Nederlands | endrin (ISO) 1,2,3,4,10,10-hexachloor-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaftaleen |
| Polish polski | endryna (ISO) rel-(1R,4S,4aS,5S,6S,7R,8R,8aR)-1,2,3,4,10,10-heksachloro-6,7-epoksy-1,4,4a,5,6,7,8,8a-oktahydro-1,4:5,8-dimetanonaftalen |
| Portuguese português | endrina (ISO) 1,2,3,4,10,10-hexacloro-6,7-epoxi-1,4,4a,5,6,7,8,8a-octa-hidro-1,4:5,8-dimetanonaftaleno |
| Romanian română | endrin (ISO) 1,2,3,4,10,10-hexacloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahidro- 1,4: 5,8-dimetanonaftalen |
| Slovak slovenčina | endrín (ISO) 1,2,3,4,10,10-hexachlór-6,7-epoxy- 1,4,4a,5,6,7,8,8a-oktahydro-1,4:5,8- dimetanonaftalén |
| Slovenian slovenščina | endrin (ISO) 1,2,3,4,10,10-heksakloro-6,7-epoksi-1,4,4a,5,6,7,8,8a-oktahidro-1,4:5,8-dimetanonaftalen |
| Finnish suomi | endriini (ISO) 1,2,3,4,10,10-heksakloori-6,7-epoksi-1,4,4a,5,6,7,8,8a-oktahydro-1,4:5,8-dimetanonaftaleeni |
| Swedish svenska | endrin (ISO) 1,2,3,4,10,10-hexaklor-6,7-epoxi-1,4,4a,5,6,7,8,8a-oktahydro-1,4:5,8-dimetanonaftalen |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Endrin GHS label elements
Everything CLP Annex VI fixes for Endrin, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Endrin
- Fatal if swallowed.
- Toxic in contact with skin.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- Immediately call a POISON CENTER/doctor/…
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Endrin in the GHS label constructor →
07 · Health hazards
Endrin health hazards and exposure limits
Endrin hazard summary
Endrin is a solid, white, almost odorless substance that was used as a pesticide to control insects, rodents, and birds. Endrin has not been produced or sold for general use in the United States since 1986. Little is known about the properties of endrin aldehyde (an impurity and breakdown product of endrin) or endrin ketone (a product of endrin when it is exposed to light).
Source: Agency for Toxic Substances and Disease Registry (ATSDR)
Endrin carcinogenicity classification
Studied by the US National Toxicology Program: TR-012: Bioassay of Endrin for Possible Carcinogenicity (CASRN 72-20-8) (1979 )
Cancer Classification: Group D Not Classifiable as to Human Carcinogenicity
Source: Hazardous Substances Data Bank (HSDB)
No data are available in humans. Inadequate evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 3: The agent is not classifiable as to its carcinogenicity to humans.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
Endrin occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | 0.1 [mg/m3] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| PEL | 0.1 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| PEL | TWA 0.1 mg/m3 [skin] | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | 0.1 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| REL | TWA 0.1 mg/m3 [skin] | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | 2 mg/m3 (NIOSH, 2024) | CAMEO Chemicals |
| IDLH | 2.0 [mg/m3] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| IDLH | 2 mg/cu m | Hazardous Substances Data Bank (HSDB) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
Endrin properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Endrin boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 245 °C (473 °F) | decomposes, decomposes | OSHA |
| Decomposes | decomposes | NIOSH | |
| Decomposes (NTP, 1992) | decomposes | CAMEO |
Endrin melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 200 °C (392 °F) | ICSC | |
| 200 °C (392 °F) | approximate, rearranges above that point | HSDB | |
| 200 °C (392 °F) | decomposes | NIOSH |
Endrin density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.7 g/cm³ | NIOSH | |
| 1.7 g/cm³ | at 20 °C | HSDB |
Endrin solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Solubility of endrin in fresh water: 200 ug/l. | HSDB | |
| Solubility in g/100 ml solvent at 25 °C: acetone 17, benzene 13.8, carbon tetrachloride 3.3, hexane 7.1, and xylene 18.3 | at 25 °C | HSDB | |
| In water, 0.25 mg/l @ 25 °C | at 25 °C | HSDB |
Endrin vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.000003 mmHg | at 20 °C | HSDB |
| 2e-7 mmHg | at 25 °C | CAMEO | |
| 0.000003 mmHg | Haz-Map |
Endrin flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 26.67 °C (80 °F) | OSHA | |
| Commercial product may contain flammable liquid with flashpoint 80F. (EPA, 1998) | CAMEO |
Endrin lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 1.1 % by volume | CAMEO | |
| 1.1 % by volume | commercial product | OSHA | |
| 1.1%-7% mixture in xylene (in air) | HSDB |
Endrin upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 7 % by volume | CAMEO | |
| 7 % by volume | commercial product | OSHA |
Endrin odor threshold
| Property | Value | Conditions | Source |
|---|---|---|---|
| Odor threshold | 1.80x10-2 ppm (perfume/flavor grade purity). | HSDB |
Endrin corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | Slightly corrosive to metals | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Endrin fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Endrin fire potential
Solid is not combustible, however it may be dissolved in a flammable solvent.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Endrin storage and handling
Endrin safe storage
Separated from food and feedstuffs. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Endrin incompatible materials
/Endrin/ has reacted violently with parathion.
Source: Hazardous Substances Data Bank (HSDB)
Endrin reactivity
While a mixture of parathion and ENDRIN was being blended into a petroleum solvent, an exothermic reaction occurred that caused some of the petroleum solvent to vaporize. The solvent-vapor-air mixture exploded. The mechanical agitation possibly initiated the exothermic reaction, Doyle(1973). Toxic hydrogen chloride and phosgene may be generated when solution burns. Avoid strong oxidizers, strong acids and parathion. [EPA, 1998].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Endrin in the storage compatibility matrix →
11 · Questions
Endrin — frequently asked questions
What is the CAS number of Endrin?
The CAS number of Endrin is 72-20-8. Its EC number is 200-775-7.
What does a Endrin label have to show?
Under CLP Annex VI the label for Endrin carries the pictograms Skull and crossbones and Environment and the signal word is Danger.
Is Endrin flammable?
CLP Annex VI assigns Endrin no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 26.67 °C (80 °F) (OSHA).
Is Endrin a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Endrin. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.
What is the exposure limit for Endrin?
The US occupational exposure limit reported for Endrin is 0.1 [mg/m3] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of Endrin?
The boiling point reported for Endrin is 245 °C (473 °F), decomposes, decomposes (OSHA).
What is the melting point of Endrin?
The melting point reported for Endrin is 200 °C (392 °F) (ICSC).
Nearby
Substances next to Endrin
Keep going: substances starting with E, or search the whole database by name, CAS number, pictogram or signal word.