Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Endothion

Endothion is crystals.

CAS 2778-04-3 Danger

01 · Identification

What Endothion is

Endothion is crystals. It melts at 96 °C.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Endothion identifiers and molecular data

Endothion CAS number and EC number

CAS number2778-04-3
EC number220-472-3
Index number (CLP Annex VI)015-049-00-3

Other names for Endothion

  • endothion (ISO)
  • S-5-methoxy-4-oxopyran-2-ylmethyl dimethyl phosphorothioate

03 · GHS classification

Endothion hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Endothion pictograms and signal word

Signal wordDanger

Endothion hazard class and category

GHS hazard classes Endothion falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 3 H311 GHS06

Endothion hazard statements (H-codes)

Hazard statements assigned to Endothion
CodeHazard statement
H311 Toxic in contact with skin.
H301 Toxic if swallowed.

This page lists only the codes assigned to Endothion. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Endothion

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Endothion issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Endothion precautionary statements

CLP Annex VI assigns 7 precautionary statements to Endothion. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Endothion name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български ендотион (ISO) S -5-метокси-4-оксопиран-2-илметилов диметилов фосфоротиоат
Spanish español Endotión (ISO) fosforotioato de S -5-metoxi-4-oxopiran-2-ilmetilo y dimetilo
Czech čeština endothion (ISO) S -[(5-methoxy-4-oxo-4 H -pyran-2-yl)methyl]- O, O -dimethyl-fosforothioát
Danish dansk endothion (ISO) S -5-methoxy-4-oxopyran-2-ylmethyldimethylthiophosphat
German Deutsch Endothion (ISO) S -5-methoxy-4-oxopyran-2-ylmethyldimethylphosphorothioat
Estonian eesti endotioon (ISO) S -5-metoksü-4-oksopüraan-2-üülmetüüldimetüülfosforotioaat
Greek ελληνικά endothion (ενδοθείο) (ISO) θειοφωσφορικό S -5-μεθοξυ-4-οξοπυραν-2-υλομεθύλιο διμεθύλιο
English English endothion (ISO) S -5-methoxy-4-oxopyran-2-ylmethyl dimethyl phosphorothioate
French français endothion (ISO) phosphorothioate de S -5-méthoxy-4-oxopyran-2-ylméthyle et de diméthyle
Croatian hrvatski endotion (ISO) S -5-metoksi-4-oksopiran-2-il-metil-dimetil-fosforotioat
Italian italiano endotion (ISO) tiofosfato di dimetile e S-5-metossi-4-ossopiran-2-ilmetile
Latvian latviešu endotions (ISO) S -5-metoksi-4-oksopirān-2-ilmetildimetilfosfortioāts
Lithuanian lietuvių endotionas (ISO) S -5-metoksi-4-oksopiran-2-ilmetildimetiltiofosfatas
Hungarian magyar endotion (ISO) S -5-metoxi-4-oxopyran-2-ilmetil-dimetil-tiofoszfát
Maltese Malti endotijon (ISO) fosforotijoat tad-dimetil ta’ S-5-metossi-4-ossopiran-2-ilmetil
Dutch Nederlands endothion (ISO) S -5-methoxy-4-oxopyran-2-ylmethyldimethylthiofosfaat
Polish polski endotion (ISO) tiofosforan S -(5-metoksypiran-4-on-2-ylo)metylu- O , O -dimetylu
Portuguese português endotião (ISO) tiofosfato de S -5-metoxi-4-oxopiran-2-ilmetilo e de dimetilo
Romanian română endotion (ISO) tiofosfat de S -5-metoxi-4- oxopiran-2-ilmetil și de dimetil
Slovak slovenčina endotión (ISO) S -[(5-metoxy-4-oxopyrán-2-yl)metyl]- O, O -dimetyl-fosforotioát
Slovenian slovenščina endotion (ISO) S -5-metoksi-4-oksopiran-2-ilmetil dimetil fosforotioat
Finnish suomi endotioni (ISO) S -5-metoksi-4-oksopyran-2-yylimetyylidimetyylifosforotioaatti
Swedish svenska endotion (ISO) S -5-metoxi-4-oxopyran-2-ylmetyldimetylfosfortioat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Endothion GHS label elements

Everything CLP Annex VI fixes for Endothion, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogram

Danger

Endothion

  • Toxic in contact with skin.
  • Toxic if swallowed.
  • Do not eat, drink or smoke when using this product.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • Immediately call a POISON CENTER/doctor/
  • Rinse mouth.
  • Wash with plenty of water/

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Endothion in the GHS label constructor →

07 · Health hazards

Endothion health hazards and exposure limits

Endothion hazard summary

A cholinesterase inhibitor; [Hawley] No adverse effects observed in 7-day feeding study of rats at 50 ppm; [HSDB] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

Endothion properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Endothion melting point

Property Value Conditions Source
Melting point 96 °C (204.8 °F) DOE PAC
90.5 °C (194.9 °F) range, midpoint shown HSDB
93.06 °C (199.5 °F) range, midpoint shown CAMEO

Endothion solubility

Property Value Conditions Source
Solubility In water, 1.5X10+6 mg/L HSDB
Soluble in olive oil; insoluble in light petroleum and cyclohexane HSDB
Soluble in acetone, benzene; insoluble in ether or carbon tetrachloride HSDB

Endothion vapor pressure

Property Value Conditions Source
Vapor pressure 0.00000569 mmHg Haz-Map

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Endothion storage and handling

Endothion storage conditions

... Must be stored in its sealed original containers, in well-aired, fresh and dry storehouses or in shaded and possibly well-aired places. It is recommended that the product's temp ... not exceed 25-30 °C, and keep ... away from sources of heat, free flames or spark-generating equipment. Containers must be stacked in such a way as to permit free circulation of air ... at bottom & inside of piles. Storage areas must be located at suitable distance from inhabited buildings, animal shelters, & food stores; moreover, they must be inaccessible to unauthorized persons, children, & domestic animals.

Source: Hazardous Substances Data Bank (HSDB)

Endothion reactivity

Organothiophosphates, such as ENDOTHION, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Endothion in the storage compatibility matrix →

10 · Questions

Endothion — frequently asked questions

What is the CAS number of Endothion?

The CAS number of Endothion is 2778-04-3. Its EC number is 220-472-3.

What does a Endothion label have to show?

Under CLP Annex VI the label for Endothion carries the pictogram Skull and crossbones and the signal word is Danger.

Is Endothion flammable?

CLP Annex VI assigns Endothion no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Endothion a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Endothion. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the melting point of Endothion?

The melting point reported for Endothion is 96 °C (204.8 °F) (DOE PAC).

How should Endothion be stored?

... Must be stored in its sealed original containers, in well-aired, fresh and dry storehouses or in shaded and possibly well-aired places. It is recommended that the product's temp ... not exceed 25-30 °C, and keep ... away from sources of heat, free flames or spark-generating equipment. Containers must be stacked in such a way as to permit free circulation of air ... at bottom & inside of piles. Storage areas must be located at suitable distance from inhabited buildings, animal shelters, & food stores; moreover, they must be inaccessible to unauthorized persons, children, & domestic animals. (Hazardous Substances Data Bank (HSDB))

Nearby

Substances next to Endothion

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