Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Ethyl acetate

Ethyl acetate is a clear, volatile with a characteristic ether-like odor reminiscent of pineapple.

CAS 141-78-6 Danger

Ethyl acetate Safety Data Sheet →

01 · Identification

What Ethyl acetate is

Ethyl acetate is a clear, volatile with a characteristic ether-like odor reminiscent of pineapple. It boils at 77.1 °C, melts at -83.8 °C.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.

02 · Identifiers

Ethyl acetate identifiers and molecular data

Ethyl acetate CAS number and EC number

CAS number141-78-6
EC number205-500-4
Index number (CLP Annex VI)607-022-00-5

Ethyl acetate molecular formula and molecular weight

Chemical class Flammable agents - 3rd degree

Other names for Ethyl acetate

  • EtOAc
  • acetic ester
  • Acetic Acid, Ethyl Ester
  • Acetic Ether
  • Acetidin
  • Acetoxyethane
  • Ethyl Acetic Ester
  • Ethyl Ester Of Acetic Acid
  • Ethyl Ethanoate
  • Vinegar Naphtha

03 · GHS classification

Ethyl acetate hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Ethyl acetate pictograms and signal word

Signal wordDanger

Ethyl acetate hazard class and category

GHS hazard classes Ethyl acetate falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 2 H225 GHS02
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Specific target organ toxicity - single exposure GHS chapter 3.8 Category 3 narcotic H336 GHS07

Ethyl acetate hazard statements (H-codes)

Hazard statements assigned to Ethyl acetate
CodeHazard statement
H225 Highly flammable liquid and vapour.
H336 May cause drowsiness or dizziness.
H319 Causes serious eye irritation.

Ethyl acetate supplemental EU statements (EUH)

EU-specific statements assigned to Ethyl acetate. They exist only in CLP and have no counterpart in UN GHS.
CodeStatement
EUH066 Repeated exposure may cause skin dryness or cracking.

This page lists only the codes assigned to Ethyl acetate. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Ethyl acetate

Our own Ethyl acetate safety data sheet walks through all sixteen sections of the published data. What it is not is the document an inspector asks for: an SDS is issued for a product by its supplier, so the sheet covering the grade actually standing in your store exists only in that supplier’s version. Collecting those and keeping them current as suppliers revise them is a separate job.

04 · Precautionary statements

Ethyl acetate precautionary statements

CLP Annex VI assigns 11 precautionary statements to Ethyl acetate. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Ethyl acetate name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български етилов ацетат
Spanish español Acetato de etilo
Czech čeština ethyl-acetát
Danish dansk ethylacetat
German Deutsch Ethylacetat Essigsäureethylester
Estonian eesti etüülatsetaat
Greek ελληνικά οξικός αιθυλεστέρας οξικό αιθύλιο
English English ethyl acetate
French français acétate d'éthyle
Croatian hrvatski etil-acetat
Italian italiano acetato di etile etilacetato
Latvian latviešu etilacetāts
Lithuanian lietuvių etilacetatas
Hungarian magyar etil-acetát
Maltese Malti aċetat etiliku
Dutch Nederlands ethylacetaat
Polish polski octan etylu
Portuguese português acetato de etilo
Romanian română acetat de etil
Slovak slovenčina etyl-acetát
Slovenian slovenščina etil acetat
Finnish suomi etyyliasetaatti
Swedish svenska etylacetat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Ethyl acetate GHS label elements

Everything CLP Annex VI fixes for Ethyl acetate, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS07 Exclamation mark pictogram

Danger

Ethyl acetate

  • Highly flammable liquid and vapour.
  • May cause drowsiness or dizziness.
  • Causes serious eye irritation.
  • Repeated exposure may cause skin dryness or cracking.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Wash thoroughly after handling.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF IN EYES:
  • Get medical advice/attention.
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Ethyl acetate in the GHS label constructor →

07 · Health hazards

Ethyl acetate health hazards and exposure limits

Ethyl acetate hazard summary

Ethyl acetate is in the list of Some volatile substances which may be abused by inhalation published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] An eye and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Ethyl acetate occupational exposure limits

US occupational exposure limits reported for Ethyl acetate. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 400.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
PEL 400 ppm (1400 mg/m³) Occupational Safety and Health Administration (OSHA)
PEL TWA 400 ppm (1400 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
REL 400 ppm (1400 mg/m³) Occupational Safety and Health Administration (OSHA)
REL TWA 400 ppm (1400 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
IDLH 2000 ppm ; Based on 10% of the lower explosive limit. (NIOSH, 2024) CAMEO Chemicals
IDLH 2000.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
IDLH 2000 ppm Occupational Safety and Health Administration (OSHA)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Ethyl acetate properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Ethyl acetate boiling point

Property Value Conditions Source
Boiling point 77.1 °C (170.8 °F) HSDB
77.22 °C (171 °F) NIOSH
77.22 °C (171 °F) at 760 mmHg CAMEO

Ethyl acetate melting point

Property Value Conditions Source
Melting point -83.8 °C (-118.8 °F) HSDB
-82.78 °C (-117 °F) NIOSH
-83.61 °C (-118.5 °F) CAMEO

Ethyl acetate density

Property Value Conditions Source
Density 0.9 g/cm³ NIOSH
0.9003 g/cm³ at 20 °C HSDB
0.902 g/cm³ at 20 °C CAMEO

Ethyl acetate solubility

Property Value Conditions Source
Solubility Miscible with ethanol, ethyl ether; very soluble in acetone, benzene HSDB
In water, 8.0X10+4 mg/L at 25 °C at 25 °C HSDB
Very soluble in water (64 g/L at 25 °C) at 25 °C HSDB

Ethyl acetate vapor pressure

Property Value Conditions Source
Vapor pressure 73 mmHg NIOSH
73 mmHg at 20 °C CAMEO
93.2 mmHg at 25 °C HSDB

Ethyl acetate flash point

Property Value Conditions Source
Flash point -4.44 °C (24 °F) NIOSH
-4 °C (24.8 °F) ICSC

Ethyl acetate autoignition temperature

Property Value Conditions Source
Autoignition temperature 426.67 °C (800 °F) CAMEO
427 °C (800.6 °F) ICSC

Ethyl acetate lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 2.2 % by volume HSDB
0.025 % by volume HSDB
2 % by volume NIOSH

Ethyl acetate upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 11.5 % by volume HSDB
0.09 % by volume HSDB

Ethyl acetate vapor density

Property Value Conditions Source
Vapor density 3.04 (air = 1) HSDB
3 (air = 1) ICSC

Ethyl acetate odor threshold

Property Value Conditions Source
Odor threshold Ethyl acetate has a fruity odor and an odor threshold of 3.9 ppm. HSDB
Detection in air: 3.6-1.120 mg cu/m HSDB
0.0196 mg/cu m (low odor); 665.0 mg/cu m (high odor); 350 mg/cu m (irritating concn) HSDB

Ethyl acetate critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 250.55 °C (483 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Ethyl acetate fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Ethyl acetate fire potential

A very dangerous fire hazard when exposed to heat or flame.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Ethyl acetate storage and handling

Ethyl acetate reactive group

CAMEO Chemicals places Ethyl acetate in the reactive group Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters. Compatibility with other chemicals is worked out from the group, not from the individual substance — which is why two substances you have never seen react can still be flagged as a pair that must be separated.

A reactive group is a CAMEO Chemicals (US NOAA) grouping, not a GHS hazard class: it has no code, no category and no legal force. It is what the storage compatibility matrix on this site computes from.

Ethyl acetate safe storage

Fireproof. Separated from strong oxidants, strong bases and strong acids.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Ethyl acetate storage conditions

Keep tightly closed in cool place.

Source: Hazardous Substances Data Bank (HSDB)

Ethyl acetate incompatible materials

... can react vigorously with oxidizing materials ... Potentially explosive reaction with lithium tetrahydroaluminate. Ignites on contact with potassium teri-butoxide. Violent reaction with chlorosulfonic acid, (LiAIH2 + 2-chloromethyl furan), oleum.

Source: Hazardous Substances Data Bank (HSDB)

Ethyl acetate reactivity

ETHYL ACETATE is also sensitive to heat. On prolonged storage, materials containing similar functional groups have formed explosive peroxides. This chemical may ignite or explode with lithium aluminum hydride. It may also ignite with potassium tert-butoxide. It is incompatible with nitrates, strong alkalis and strong acids. It will attack some forms of plastics, rubber and coatings. It is incompatible with oxidizers such as hydrogen peroxide, nitric acid, perchloric acid and chromium trioxide. Violent reactions occur with chlorosulfonic acid. (NTP, 1992). SOCl2 reacts with esters, such as ethyl acetate, forming toxic SO2 gas and water soluble/toxic acyl chlorides, catalyzed by Fe or Zn (Spagnuolo, C.J. et al. 1992. Chemical and Engineering News 70(22):2.).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Ethyl acetate in the storage compatibility matrix →

11 · Transport

Ethyl acetate UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Ethyl acetate under UN 1173 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
ETHYL ACETATE 3 F1 II
  • ADR label model 3 — Flammable liquid
3

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 3 is “Flammable liquids” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Ethyl acetate 3 II
  • US DOT FLAMMABLE LIQUID label (§172.419)
3

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 3 is “Flammable and combustible liquid” (49 CFR 173.2).

Full UN 1173 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

Ethyl acetate — frequently asked questions

What is the CAS number of Ethyl acetate?

The CAS number of Ethyl acetate is 141-78-6. Its EC number is 205-500-4.

What does a Ethyl acetate label have to show?

Under CLP Annex VI the label for Ethyl acetate carries the pictograms Flame and Exclamation mark and the signal word is Danger.

Is Ethyl acetate flammable?

Yes. CLP Annex VI assigns Ethyl acetate H225 — highly flammable liquid and vapour. The flash point reported for it is -4.44 °C (24 °F) (NIOSH).

Is Ethyl acetate a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Ethyl acetate. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Ethyl acetate?

The US occupational exposure limit reported for Ethyl acetate is 400.0 [ppm] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Ethyl acetate?

The boiling point reported for Ethyl acetate is 77.1 °C (170.8 °F) (HSDB).

What is the melting point of Ethyl acetate?

The melting point reported for Ethyl acetate is -83.8 °C (-118.8 °F) (HSDB).

How should Ethyl acetate be stored?

CLP Annex VI assigns Ethyl acetate the storage statement P403. Keep tightly closed in cool place. (Hazardous Substances Data Bank (HSDB))

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