Substance profile
Ethyl p-nitrophenyl benzenethiophosphonate
Ethyl p-nitrophenyl benzenethiophosphonate is light yellow crystals with an aromatic odor.
01 · Identification
What Ethyl p-nitrophenyl… is
Ethyl p-nitrophenyl benzenethiophosphonate is light yellow crystals with an aromatic odor. Its molecular formula is C14H14NO4PS and its molecular weight is 323.31 g/mol. It melts at 36 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Ethyl p-nitrophenyl… identifiers and molecular data
Ethyl p-nitrophenyl… CAS number and EC number
Ethyl p-nitrophenyl… molecular formula and molecular weight
Other names for Ethyl p-nitrophenyl…
- O-ethyl O-4-nitrophenyl phenylphosphonothioate
- EPN
03 · GHS classification
Ethyl p-nitrophenyl… hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Ethyl p-nitrophenyl… pictograms and signal word
Ethyl p-nitrophenyl… hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 1 or 2 | H310 | GHS06 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Ethyl p-nitrophenyl… hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H310 | Fatal in contact with skin. |
| H300 | Fatal if swallowed. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Ethyl p-nitrophenyl…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Ethyl p-nitrophenyl…
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Ethyl p-nitrophenyl… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Ethyl p-nitrophenyl… precautionary statements
CLP Annex VI assigns 10 precautionary statements to Ethyl p-nitrophenyl…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Ethyl p-nitrophenyl… name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | О -етилов О -4-нитрофенилов фенилфосфонотиоат EPN |
| Spanish español | Fenilfosfonotioato de O -etilo y O -4-nitrofenilo EPN |
| Czech čeština | O -ethyl- O -(4-nitrofenyl)-fenylfosfonothioát EPN |
| Danish dansk | O- ethyl- O- 4-nitrophenylphenylthiophosphonat EPN |
| German Deutsch | O -Ethyl- O -4-nitrophenylphenylthiophosphonat EPN |
| Estonian eesti | O -etüül- O -4-nitrofenüülfenüülfosfonotioaat EPN |
| Greek ελληνικά | φαινυλοθειοφωσφονικό O -αιθύλιο O -4-νιτροφαινύλιο EPN |
| English English | O -ethyl O -4-nitrophenyl phenylphosphonothioate EPN |
| French français | phénylphosphonothioate de O -éthyle et de O -4-nitrophényle EPN |
| Croatian hrvatski | O -etil- O -4-nitrofenil-fenil-fosfonotioat EPN |
| Italian italiano | feniltiofosfonato di O-etile e O-4-nitrofenile EPN |
| Latvian latviešu | O -etil- O -4-nitrofenila fenilfosfontioāts EPN |
| Lithuanian lietuvių | O -etil- O -4-nitrofenilfeniltiofosfonatas EPN |
| Hungarian magyar | O -etil O -4-nitrofenil-fenil-tiofoszfonát EPN |
| Maltese Malti | fenilfosfonotijoat ta’ O -etil O -4-nitrofenil EPN |
| Dutch Nederlands | O -ethyl- O -4-nitrofenylfenylthiofosfonaat EPN |
| Polish polski | fenylotiofosfonian O -etylu- O -4-nitrofenylu EPN |
| Portuguese português | feniltiofosfonato de O -etilo e de O -4-nitrofenilo EPN |
| Romanian română | feniltiofosfat de O -etil și de O -4-nitrofenil EPN |
| Slovak slovenčina | O -etyl- O -(4-nitrofenyl)-fenylfosfonotioát EPN |
| Slovenian slovenščina | O -etil O -4-nitrofenil fenilfosfonotioat EPN |
| Finnish suomi | EPN O -etyyli- O -(4-nitrofenyyli)fenyylifosfonotioaatti |
| Swedish svenska | O -etyl- O -4-nitrofenylfenylfosfonotioat EPN |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Ethyl p-nitrophenyl… GHS label elements
Everything CLP Annex VI fixes for Ethyl p-nitrophenyl…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Ethyl p-nitrophenyl…
- Fatal in contact with skin.
- Fatal if swallowed.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- Immediately call a POISON CENTER/doctor/…
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Ethyl p-nitrophenyl… in the GHS label constructor →
07 · Health hazards
Ethyl p-nitrophenyl… health hazards and exposure limits
Ethyl p-nitrophenyl… hazard summary
A small number of the organophosphates (OPs) can Induce Delayed Neuropathy (OPIDN). OPIDN usually occurs after ingestion and is usually nonoccupational. [Levy, p. 431] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Ethyl p-nitrophenyl… occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | 0.5 [mg/m3] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| PEL | 0.5 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| PEL | TWA 0.5 mg/m3 [skin] | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | 0.5 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| REL | TWA 0.5 mg/m3 [skin] | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | 5 mg/m3 (NIOSH, 2024) | CAMEO Chemicals |
| IDLH | 5.0 [mg/m3] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| IDLH | 5 mg/cu m | Hazardous Substances Data Bank (HSDB) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
Ethyl p-nitrophenyl… properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Ethyl p-nitrophenyl… boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 215 °C (419 °F) | at 5 mmHg (reduced pressure) | HSDB |
| 215 °C (419 °F) | at 5.00291 mmHg (reduced pressure) | ICSC |
Ethyl p-nitrophenyl… melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 36 °C (96.8 °F) | HSDB | |
| 36.11 °C (97 °F) | NIOSH |
Ethyl p-nitrophenyl… density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.3 g/cm³ | ICSC | |
| 1.27 g/cm³ | at 25 °C | HSDB | |
| 1.268 g/cm³ | at 25 °C | CAMEO |
Ethyl p-nitrophenyl… solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Miscible with isopropanol, benzene, toluene, xylene, acetone, methanol | HSDB | |
| Very sol in ether, ethanol | HSDB | ||
| In water, 3.11 mg/l @ 20-25 °C | HSDB |
Ethyl p-nitrophenyl… vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.0003 mmHg | OSHA | |
| 9.5e-7 mmHg | at 25 °C | HSDB | |
| 0.0003 mmHg | at 100 °C | NIOSH |
Ethyl p-nitrophenyl… lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Noncombustible Solid | NIOSH |
Ethyl p-nitrophenyl… corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | Non-corrosive | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Ethyl p-nitrophenyl… storage and handling
Ethyl p-nitrophenyl… safe storage
Separated from strong oxidizers and food and feedstuffs. Well closed. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Ethyl p-nitrophenyl… storage conditions
Keep away from heat and open flame. Keep container closed. Store at 65-100 °F.
Source: Hazardous Substances Data Bank (HSDB)
Ethyl p-nitrophenyl… incompatible materials
Strong oxidizers
Source: Hazardous Substances Data Bank (HSDB)
Ethyl p-nitrophenyl… reactivity
Organophosphates, such as EPN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Ethyl p-nitrophenyl… in the storage compatibility matrix →
10 · Questions
Ethyl p-nitrophenyl… — frequently asked questions
What is the CAS number of Ethyl p-nitrophenyl…?
The CAS number of Ethyl p-nitrophenyl… is 2104-64-5. Its EC number is 218-276-8.
What is the chemical formula of Ethyl p-nitrophenyl…?
The molecular formula of Ethyl p-nitrophenyl… is C14H14NO4PS and its molecular weight is 323.31 g/mol.
What does a Ethyl p-nitrophenyl… label have to show?
Under CLP Annex VI the label for Ethyl p-nitrophenyl… carries the pictograms Skull and crossbones and Environment and the signal word is Danger.
Is Ethyl p-nitrophenyl… flammable?
CLP Annex VI assigns Ethyl p-nitrophenyl… no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Ethyl p-nitrophenyl… a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Ethyl p-nitrophenyl…. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the exposure limit for Ethyl p-nitrophenyl…?
The US occupational exposure limit reported for Ethyl p-nitrophenyl… is 0.5 [mg/m3] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of Ethyl p-nitrophenyl…?
The boiling point reported for Ethyl p-nitrophenyl… is 215 °C (419 °F), at 5 mmHg (reduced pressure) (HSDB).
What is the melting point of Ethyl p-nitrophenyl…?
The melting point reported for Ethyl p-nitrophenyl… is 36 °C (96.8 °F) (HSDB).
How should Ethyl p-nitrophenyl… be stored?
Keep away from heat and open flame. Keep container closed. Store at 65-100 °F. (Hazardous Substances Data Bank (HSDB))
Nearby
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