Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Fenamiphos

Fenamiphos is colorless crystals.

CAS 22224-92-6 C13H22NO3PS 303.36 g/mol Danger

01 · Identification

What Fenamiphos is

Fenamiphos is colorless crystals. Its molecular formula is C13H22NO3PS and its molecular weight is 303.36 g/mol. It boils at 450 °C, melts at 49 °C.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Fenamiphos identifiers and molecular data

Fenamiphos CAS number and EC number

CAS number22224-92-6
EC number244-848-1
Index number (CLP Annex VI)015-123-00-5

Fenamiphos molecular formula and molecular weight

Molecular formulaC13H22NO3PS
Molecular weight303.36 g/mol

Other names for Fenamiphos

  • fenamiphos (ISO)
  • ethyl-4-methylthio-m-tolyl isopropyl phosphoramidate

03 · GHS classification

Fenamiphos hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Fenamiphos pictograms and signal word

Signal wordDanger

Fenamiphos hazard class and category

GHS hazard classes Fenamiphos falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 1 or 2 H300 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 1 or 2 H310 GHS06
Acute toxicity - inhalation GHS chapter 3.1 Category 1 or 2 H330 GHS06
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Fenamiphos hazard statements (H-codes)

Hazard statements assigned to Fenamiphos
CodeHazard statement
H330 Fatal if inhaled.
H310 Fatal in contact with skin.
H300 Fatal if swallowed.
H319 Causes serious eye irritation.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Fenamiphos. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Fenamiphos

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Fenamiphos issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Fenamiphos precautionary statements

CLP Annex VI assigns 18 precautionary statements to Fenamiphos. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Fenamiphos name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български фенамифос (ISO) етил-4-метилтио- m -толилов изопропилов фосфорамидат
Spanish español Fenamifós (ISO) isopropilfosforamidato de etilo y 4-metiltio- m -tolilo
Czech čeština fenamifos (ISO) ethyl-3-methyl-4-(methylsulfanyl)fenyl- N -isopropylfosforamidát
Danish dansk fenamiphos (ISO) ethyl-4-methylthio-m-tolyl- N- isopropylphosphoramidat
German Deutsch Fenamiphos (ISO) Ethyl-4-methylthio- m -tolylisopropylphosphoramidat
Estonian eesti fenamifoss (ISO) etüül-4-metüültio- m -tolüülisopropüülfosforamidaat
Greek ελληνικά fenamiphos (φαιναμιφός) (ISO) φωσφοραμιδικό αιθυλο-4-μεθυλοθειο- m -τολύλιο ισοπροπύλιο
English English fenamiphos (ISO) ethyl-4-methylthio- m -tolyl isopropyl phosphoramidate
French français fénamiphos (ISO) phosphoramidate d'éthyl-4-méthylthio- m -tolyle et d'isopropyle
Croatian hrvatski fenamifos (ISO) etil-4-metil-tio- m -tolil-izopropil-fosforamidat
Italian italiano fenamifos (ISO) N -isopropilfosforammidato di etile e 4-metiltio- m -tolile
Latvian latviešu fenamifoss (ISO) etil-4-metiltio- m -tolilizopropilfosforamidāts
Lithuanian lietuvių fenamifosas (ISO) etil-4-metiltio- m -tolilizopropilamidofosfatas
Hungarian magyar fenamifosz (ISO) etil-4-metiltio- m -tolil-izopropil-foszforamidát
Maltese Malti fenamifos (ISO) fosforamidat ta’ isopropil tal-etil-4-metiltijo-m-tolil
Dutch Nederlands fenamifos (ISO) ethyl-4-methylthio- m -tolyl- N -isopropylfosforamidaat
Polish polski fenamifos (ISO) izopropyloamidofosforan etylu-3-metylo-4-(metylosulfanylo)fenylu
Portuguese português fenamifos (ISO) isopropilfosforamidato de etilo e de 4-metiltio- m -tolilo
Romanian română fenamifos (ISO) izopropilfosforamidat de etil și de 4-metiltio- m -tolil
Slovak slovenčina fenamifos (ISO) etyl-[3-metyl-4-(metylsulfanyl)fenyl]- N -izopropylfosforamidát
Slovenian slovenščina fenamifos (ISO) etil-4-metiltio- m -tolil izopropil fosforamidat
Finnish suomi fenamifossi (ISO) etyyli-4-metyylitio- m -tolyyli-isopropyylifosforamidaatti
Swedish svenska fenamifos (ISO) etyl-4-metyltio- m -tolylisopropylfosforamidat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Fenamiphos GHS label elements

Everything CLP Annex VI fixes for Fenamiphos, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS09 Environment pictogram

Danger

Fenamiphos

  • Fatal if inhaled.
  • Fatal in contact with skin.
  • Fatal if swallowed.
  • Causes serious eye irritation.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Wash thoroughly after handling.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF INHALED:
  • IF IN EYES:
  • Immediately call a POISON CENTER/doctor/
  • Get medical advice/attention.
  • Rinse mouth.
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Fenamiphos in the GHS label constructor →

07 · Health hazards

Fenamiphos health hazards and exposure limits

Fenamiphos hazard summary

Classified as highly toxic and may be used only by a certified applicator; [EXTOXNET] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Fenamiphos carcinogenicity classification

Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

Fenamiphos occupational exposure limits

US occupational exposure limits reported for Fenamiphos. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL none See Appendix G The National Institute for Occupational Safety and Health (NIOSH)
REL 0.1 mg/m³ Occupational Safety and Health Administration (OSHA)
REL TWA 0.1 mg/m3 [skin] The National Institute for Occupational Safety and Health (NIOSH)
IDLH N.D. The National Institute for Occupational Safety and Health (NIOSH)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Fenamiphos properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Fenamiphos boiling point

Property Value Conditions Source
Boiling point 450 °C (842 °F) at 760 mmHg DOE PAC
Decomposes (NTP, 1992) decomposes CAMEO
decomposes decomposes OSHA

Fenamiphos melting point

Property Value Conditions Source
Melting point 49 °C (120.2 °F) HSDB
49.44 °C (121 °F) NIOSH

Fenamiphos density

Property Value Conditions Source
Density 1.14 g/cm³ NIOSH
1.15 g/cm³ ICSC

Fenamiphos solubility

Property Value Conditions Source
Solubility In water, 400 mg/L at 20 °C at 20 °C HSDB
In water, 329 mg/L at 20 °C at 20 °C HSDB
In dichloromethane, isopropanol, toluene > 200; hexane 10-20 (all in g/L, 20 °C) at 20 °C HSDB

Fenamiphos vapor pressure

Property Value Conditions Source
Vapor pressure 0.00005 mmHg NIOSH
0.000009 mmHg at 20 °C HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Fenamiphos fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Fenamiphos fire potential

Flash point data for this compound are not available, however, it is probably combustible.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Fenamiphos storage and handling

Fenamiphos safe storage

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Fenamiphos storage conditions

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed.

Source: Hazardous Substances Data Bank (HSDB)

Fenamiphos incompatible materials

May hydrolyze under alkaline conditions.

Source: Hazardous Substances Data Bank (HSDB)

Fenamiphos reactivity

Organothiophosphates, such as FENAMIPHOS, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Fenamiphos in the storage compatibility matrix →

11 · Questions

Fenamiphos — frequently asked questions

What is the CAS number of Fenamiphos?

The CAS number of Fenamiphos is 22224-92-6. Its EC number is 244-848-1.

What is the chemical formula of Fenamiphos?

The molecular formula of Fenamiphos is C13H22NO3PS and its molecular weight is 303.36 g/mol.

What does a Fenamiphos label have to show?

Under CLP Annex VI the label for Fenamiphos carries the pictograms Skull and crossbones and Environment and the signal word is Danger.

Is Fenamiphos flammable?

CLP Annex VI assigns Fenamiphos no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Fenamiphos a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Fenamiphos. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Fenamiphos?

The US occupational exposure limit reported for Fenamiphos is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Fenamiphos?

The boiling point reported for Fenamiphos is 450 °C (842 °F), at 760 mmHg (DOE PAC).

What is the melting point of Fenamiphos?

The melting point reported for Fenamiphos is 49 °C (120.2 °F) (HSDB).

How should Fenamiphos be stored?

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. (Hazardous Substances Data Bank (HSDB))

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