Substance profile
Fluoroacetamide
Fluoroacetamide is a colorless crystalline powder.
01 · Identification
What Fluoroacetamide is
Fluoroacetamide is a colorless crystalline powder. Its molecular formula is C2H4FNO and its molecular weight is 77.06 g/mol. It boils at 250 °C, melts at 108 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Fluoroacetamide identifiers and molecular data
Fluoroacetamide CAS number and EC number
Fluoroacetamide molecular formula and molecular weight
Other names for Fluoroacetamide
- 2-fluoroacetamide
03 · GHS classification
Fluoroacetamide hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Fluoroacetamide pictograms and signal word
Fluoroacetamide hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 3 | H311 | GHS06 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Fluoroacetamide hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H300 | Fatal if swallowed. |
| H311 | Toxic in contact with skin. |
This page lists only the codes assigned to Fluoroacetamide. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Fluoroacetamide
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Fluoroacetamide issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Fluoroacetamide precautionary statements
CLP Annex VI assigns 7 precautionary statements to Fluoroacetamide. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Fluoroacetamide name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 2-флуороацетамид |
| Spanish español | 2-Fluoroacetamida |
| Czech čeština | 2-fluoracetamid |
| Danish dansk | 2-fluoracetamid |
| German Deutsch | 2-Fluoracetamid |
| Estonian eesti | 2-fluoroatseetamiid |
| Greek ελληνικά | 2-φθορακεταμίδιο |
| English English | 2-fluoroacetamide |
| French français | 2-fluoroacétamide |
| Croatian hrvatski | 2-fluoracetamid |
| Italian italiano | 2-fluoroacetammide |
| Latvian latviešu | 2-fluoracetamīds |
| Lithuanian lietuvių | 2-fluoracetamidas |
| Hungarian magyar | 2-fluoracetamid |
| Maltese Malti | 2-fluworoaċetammid |
| Dutch Nederlands | 2-fluoraceetamide |
| Polish polski | 2-fluoroacetamid |
| Portuguese português | 2-fluoroacetamida |
| Romanian română | 2-fluoroacetamidă |
| Slovak slovenčina | 2-fluóracetamid |
| Slovenian slovenščina | 2-fluoroacetamid |
| Finnish suomi | 2-fluoriasetamidi |
| Swedish svenska | 2-fluoracetamid |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Fluoroacetamide GHS label elements
Everything CLP Annex VI fixes for Fluoroacetamide, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Fluoroacetamide
- Fatal if swallowed.
- Toxic in contact with skin.
- Do not eat, drink or smoke when using this product.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- Immediately call a POISON CENTER/doctor/…
- Rinse mouth.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Fluoroacetamide in the GHS label constructor →
07 · Health hazards
Fluoroacetamide health hazards and exposure limits
Fluoroacetamide hazard summary
Can be absorbed through skin; In animal experiments, toxic to the heart (fatal arrhythmias) and reproductive system; [ICSC] A testicular poison in animal studies; [HSDB] Probable oral lethal dose in humans is less than 5 mg/kg (less than 7 drops); Inhibits oxygen metabolism by cells; [CAMEO] Converted to fluoroacetic acid in vivo causing buildup of fluorocitric acid and inhibiting Krebs cycle; [UNEP] May cause irritation; Can be absorbed through skin; Metabolized to fluoroacetate (highly toxic); [MSDSonline] See Sodium fluoroacetate.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Fluoroacetamide properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Fluoroacetamide boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 250 °C (482 °F) | at 760 mmHg | DOE PAC |
| Sublimes | sublimes | HSDB | |
| Sublimes on heating (EPA, 1998) | sublimes | CAMEO |
Fluoroacetamide melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 108 °C (226.4 °F) | HSDB | |
| 107 °C (224.6 °F) | ICSC | ||
| 108.06 °C (226.5 °F) | range, midpoint shown | CAMEO |
Fluoroacetamide solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Freely sol in water, sol in acetone; sparingly sol in chloroform | HSDB | |
| Moderately sol in ethanol; sparingly sol in aliphatic and aromatic hydrocarbons | HSDB | ||
| Solubility in water: very good | ICSC |
Fluoroacetamide vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.001 mmHg | at 25 °C | DOE PAC |
| 0.99 mmHg | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Fluoroacetamide storage and handling
Fluoroacetamide safe storage
Separated from acids.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Fluoroacetamide storage conditions
STORE IN CLOSED CONTAINERS IN CLOSED AREA.
Source: Hazardous Substances Data Bank (HSDB)
Fluoroacetamide reactivity
FLUOROACETAMIDE is a fluorinated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Fluoroacetamide in the storage compatibility matrix →
10 · Questions
Fluoroacetamide — frequently asked questions
What is the CAS number of Fluoroacetamide?
The CAS number of Fluoroacetamide is 640-19-7. Its EC number is 211-363-1.
What is the chemical formula of Fluoroacetamide?
The molecular formula of Fluoroacetamide is C2H4FNO and its molecular weight is 77.06 g/mol.
What does a Fluoroacetamide label have to show?
Under CLP Annex VI the label for Fluoroacetamide carries the pictogram Skull and crossbones and the signal word is Danger.
Is Fluoroacetamide flammable?
CLP Annex VI assigns Fluoroacetamide no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Fluoroacetamide a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Fluoroacetamide. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Fluoroacetamide?
The boiling point reported for Fluoroacetamide is 250 °C (482 °F), at 760 mmHg (DOE PAC).
What is the melting point of Fluoroacetamide?
The melting point reported for Fluoroacetamide is 108 °C (226.4 °F) (HSDB).
How should Fluoroacetamide be stored?
STORE IN CLOSED CONTAINERS IN CLOSED AREA. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Fluoroacetamide
Keep going: substances starting with F, or search the whole database by name, CAS number, pictogram or signal word.