Substance profile
Hexafluoropropylene
Hexafluoropropylene is a colorless gas and is odorless.
01 · Identification
What Hexafluoropropylene is
Hexafluoropropylene is a colorless gas and is odorless. Its molecular formula is C3F6 and its molecular weight is 150.02 g/mol. It boils at -29.6 °C, melts at -156 °C.
Under the GHS it carries the signal word Warning. It is classed as reactive agents - 1st degree.
02 · Identifiers
Hexafluoropropylene identifiers and molecular data
Hexafluoropropylene CAS number and EC number
Hexafluoropropylene molecular formula and molecular weight
Other names for Hexafluoropropylene
- hexafluoropropene
03 · GHS classification
Hexafluoropropylene hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Hexafluoropropylene pictograms and signal word
Hexafluoropropylene hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - inhalation GHS chapter 3.1 | Category 4 | H332 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 | H335 | GHS07 |
Hexafluoropropylene hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H332 | Harmful if inhaled. |
| H335 | May cause respiratory irritation. |
This page lists only the codes assigned to Hexafluoropropylene. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Hexafluoropropylene
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Hexafluoropropylene issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Hexafluoropropylene precautionary statements
CLP Annex VI assigns 4 precautionary statements to Hexafluoropropylene. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Hexafluoropropylene name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | хексафлуоропропен хексафлуоропропилен |
| Spanish español | Hexafluoropropeno hexafluoropropileno |
| Czech čeština | hexafluorpropen hexafluorpropylen |
| Danish dansk | hexafluorpropen hexaflourpropylen |
| German Deutsch | Hexafluorpropen Hexafluorpropylen |
| Estonian eesti | heksafluoropropeen heksafluoropropüleen |
| Greek ελληνικά | εξαφθοροπροπένιο εξαφθοροπροπυλένιο |
| English English | hexafluoropropene hexafluoropropylene |
| French français | hexafluoropropène hexafluoropropylène |
| Croatian hrvatski | heksafluorpropen heksafluorpropilen |
| Italian italiano | esafluoropropene perfluoropropene |
| Latvian latviešu | heksafluorpropēns heksafluorpropilēns |
| Lithuanian lietuvių | heksafluorpropenas heksafluorpropilenas |
| Hungarian magyar | hexafluorpropén hexafluorpropilén |
| Maltese Malti | essafluworopropen dietilentriammina |
| Dutch Nederlands | perfluorpropeen hexafluorpropeen |
| Polish polski | heksafluoropropen heksafluoropropylenperfluoropropylen |
| Portuguese português | hexafluoropropeno hexafluoropropileno |
| Romanian română | hexafloropropenă hexafluoropropilenă |
| Slovak slovenčina | hexafluórpropén hexafluórpropylén |
| Slovenian slovenščina | heksafluoropropen heksafluoropropilen |
| Finnish suomi | heksafluoripropeeni heksafluoripropyleeni |
| Swedish svenska | hexafluorpropen hexafluorpropylen |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Hexafluoropropylene GHS label elements
Everything CLP Annex VI fixes for Hexafluoropropylene, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Hexafluoropropylene
- Harmful if inhaled.
- May cause respiratory irritation.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Use only outdoors or in a well-ventilated area.
- IF INHALED:
- Call a POISON CENTER/doctor/… if you feel unwell.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Hexafluoropropylene in the GHS label constructor →
07 · Health hazards
Hexafluoropropylene health hazards and exposure limits
Hexafluoropropylene hazard summary
Produces acute tubular necrosis in experimental animals exposed to high concentrations; [HSDB] A respiratory tract irritant; The kidney is the target organ; [ACGIH]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Hexafluoropropylene properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Hexafluoropropylene boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | -29.6 °C (-21.3 °F) | HSDB | |
| -29.6 °C (-21.3 °F) | at 760 mmHg | DOE PAC |
Hexafluoropropylene melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -156.5 °C (-249.7 °F) | HSDB |
Hexafluoropropylene density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.583 g/cm³ | at -40 °C | HSDB |
Hexafluoropropylene vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 4900 mmHg | at 25 °C | HSDB |
| 750 mmHg | at -30.6 °C | DOE PAC | |
| 4900 mmHg | Haz-Map |
Hexafluoropropylene lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | EXPLOSIVE OR SIMILARLY VIGOROUS REACTIONS BETWEEN HALOGENATED HYDROCARBONS AND OTHER CHEM ARE DESCRIBED. | HSDB |
Hexafluoropropylene critical temperature and pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Critical temperature and pressure | 2 °C (35.6 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Hexafluoropropylene storage and handling
Hexafluoropropylene incompatible materials
Reaction of various substituted phenylmagnesium bromides with hexafluoropropene under pressure at ambient temp had been effected on the 0.2-0.6 g mol scale without incident. An attempt to scale up to 0.8 g mol with phenylmagnesium bromide led to an explosion.
Source: Hazardous Substances Data Bank (HSDB)
Hexafluoropropylene reactivity
Halogenated aliphatic compounds, such as HEXAFLUOROPROPYLENE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. Above a minimum oxygen pressure, the reaction of oxygen difluoride and hexafluoropropene to yield the hexafluoropropylene oxide becomes explosive, Chem. Abs., 1987, 107, 175302. The reaction of hexafluoropropene with grignard reagent (subst. phenylmagnesium bromides) led to explosion, Fluorine Chem., 1981, 18, 25.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Hexafluoropropylene in the storage compatibility matrix →
10 · Transport
Hexafluoropropylene UN number and transport classification
Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.
Hexafluoropropylene under UN 1858 — shipping name, class and packing group
Europe · ADR 2025, Table A
| Proper shipping name (3.1.2) | Class | Classification code | PG | Labels (column 5) |
|---|---|---|---|---|
| HEXAFLUOROPROPYLENE (REFRIGERANT GAS R 1216) | 2 | 2A | — | |
Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 2 is “Gases” (ADR 2.1.1.1).
United States · 49 CFR 172.101 Hazardous Materials Table
| Proper shipping name (column 2) | Class or division | PG | Labels (column 6) |
|---|---|---|---|
| Hexafluoropropylene compressed or Refrigerant gas R 1216 | 2.2 | — | |
Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 2.2 is “Non-flammable compressed gas” (49 CFR 173.2).
11 · Questions
Hexafluoropropylene — frequently asked questions
What is the CAS number of Hexafluoropropylene?
The CAS number of Hexafluoropropylene is 116-15-4. Its EC number is 204-127-4.
What is the chemical formula of Hexafluoropropylene?
The molecular formula of Hexafluoropropylene is C3F6 and its molecular weight is 150.02 g/mol.
What does a Hexafluoropropylene label have to show?
Under CLP Annex VI the label for Hexafluoropropylene carries the pictogram Exclamation mark and the signal word is Warning.
Is Hexafluoropropylene flammable?
CLP Annex VI assigns Hexafluoropropylene no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Hexafluoropropylene a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Hexafluoropropylene. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Hexafluoropropylene?
The boiling point reported for Hexafluoropropylene is -29.6 °C (-21.3 °F) (HSDB).
What is the melting point of Hexafluoropropylene?
The melting point reported for Hexafluoropropylene is -156.5 °C (-249.7 °F) (HSDB).
Nearby
Substances next to Hexafluoropropylene
Keep going: substances starting with H, or search the whole database by name, CAS number, pictogram or signal word.