Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Isopropyl alcohol

Isopropyl alcohol is a colorless liquid with a pleasant odor.

CAS 67-63-0 C3H8O 60.1 g/mol Danger

Isopropyl alcohol Safety Data Sheet →

01 · Identification

What Isopropyl alcohol is

Isopropyl alcohol is a colorless liquid with a pleasant odor. Its molecular formula is C3H8O and its molecular weight is 60.1 g/mol. It boils at 82.3 °C, melts at -87.9 °C, is very soluble in water.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.

02 · Identifiers

Isopropyl alcohol identifiers and molecular data

Isopropyl alcohol CAS number and EC number

CAS number67-63-0
EC number200-661-7
Index number (CLP Annex VI)603-117-00-0

Isopropyl alcohol molecular formula and molecular weight

Molecular formulaC3H8O
Molecular weight60.1 g/mol
Chemical class Flammable agents - 3rd degree

Other names for Isopropyl alcohol

  • IPA
  • isopropanol
  • rubbing alcohol
  • 2-propanol
  • Alcojel
  • Alcosolve
  • Alcosolve 2
  • Autosept
  • Avantin
  • Avantine
  • Chromar
  • Combi-Schutz
  • Dimethyl Carbinol
  • Dimethylcarbinol
  • Hartosol
  • 2-Hydroxypropane
  • propan-2-ol

03 · GHS classification

Isopropyl alcohol hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Isopropyl alcohol pictograms and signal word

Signal wordDanger

Isopropyl alcohol hazard class and category

GHS hazard classes Isopropyl alcohol falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 2 H225 GHS02
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Specific target organ toxicity - single exposure GHS chapter 3.8 Category 3 narcotic H336 GHS07

Isopropyl alcohol hazard statements (H-codes)

Hazard statements assigned to Isopropyl alcohol
CodeHazard statement
H225 Highly flammable liquid and vapour.
H336 May cause drowsiness or dizziness.
H319 Causes serious eye irritation.

This page lists only the codes assigned to Isopropyl alcohol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Isopropyl alcohol

Our own Isopropyl alcohol safety data sheet walks through all sixteen sections of the published data. What it is not is the document an inspector asks for: an SDS is issued for a product by its supplier, so the sheet covering the grade actually standing in your store exists only in that supplier’s version. Collecting those and keeping them current as suppliers revise them is a separate job.

04 · Precautionary statements

Isopropyl alcohol precautionary statements

CLP Annex VI assigns 11 precautionary statements to Isopropyl alcohol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Isopropyl alcohol name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български пропан-2-ол изопропилов алкохолизопропанол
Spanish español Propan-2-ol alcohol isopropílicoisopropanol
Czech čeština propan-2-ol isopropyl-alkoholisopropanol
Danish dansk propan-2-ol isopropylalkoholisopropanol
German Deutsch 2-Propanol IsopropylalkoholIsopropanol
Estonian eesti propaan-2-ool isopropüülalkoholisopropanool
Greek ελληνικά προπαν-2-όλη ισοπροπυλική αλκοόληισοπροπανόλη
English English propan-2-ol isopropyl alcoholisopropanol
French français propan-2-ol alcool isopropyliqueisopropanol
Croatian hrvatski propan-2-ol izopropil-alkoholizopropanol
Italian italiano propan-2-olo alcool isopropilicoisopropanolo
Latvian latviešu propān-2-ols izopropilspirtsizopropanols
Lithuanian lietuvių propan-2-olis izopropilo alkoholisizopropanolis
Hungarian magyar propán-2-ol izopropil-alkoholizopropanol
Maltese Malti propan-2-ol alkoħol tal-isopropilisopropanol
Dutch Nederlands propaan-2-ol isopropylalcoholisopropanol
Polish polski propan-2-ol alkohol izopropylowyizopropanol
Portuguese português propan-2-ol álcool isopropílicoisopropanol
Romanian română propan-2-ol alcool izopropilicizopropanol
Slovak slovenčina propán-2-ol izopropylalkoholizopropanol
Slovenian slovenščina propan-2-ol izopropil alkoholizopropanol
Finnish suomi propan-2-oli isopropyylialkoholiisopropanoli
Swedish svenska propan-2-ol isopropylalkoholisopropanol

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Isopropyl alcohol GHS label elements

Everything CLP Annex VI fixes for Isopropyl alcohol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS07 Exclamation mark pictogram

Danger

Isopropyl alcohol

  • Highly flammable liquid and vapour.
  • May cause drowsiness or dizziness.
  • Causes serious eye irritation.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Wash thoroughly after handling.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF IN EYES:
  • Get medical advice/attention.
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Isopropyl alcohol in the GHS label constructor →

07 · Health hazards

Isopropyl alcohol health hazards and exposure limits

Isopropyl alcohol hazard summary

Isopropyl alcohol causes narcosis in acute animal studies. [ACGIH] Isopropyl alcohol is not hepatotoxic in experimental animal studies or in human exposures. [Zimmerman, p. 367] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Isopropyl alcohol carcinogenicity classification

IARC classification Group 3 — Not classifiable as to its carcinogenicity to humans
IARC monographs Volume 15: (1977) Some Fumigants, the Herbicides 2,4-D and 2,4,5-T, Chlorinated Dibenzodioxins and Miscellaneous Industrial Chemicals; Volume 71: (1999) Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide (Part 1, Part 2, Part 3)

Evaluation: There is inadequate evidence for the carcinogenicity of isopropanol in humans. There is inadequate evidence for the carcinogenicity of isopropanol in experimental animals. Overall evaluation: Isopropanol is not classifiable as to its carcinogenicity to humans (Group 3).

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

Isopropyl alcohol occupational exposure limits

US occupational exposure limits reported for Isopropyl alcohol. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 400.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
PEL 400 ppm (980 mg/m³) Occupational Safety and Health Administration (OSHA)
PEL TWA 400 ppm (980 mg/m3) See Appendix G The National Institute for Occupational Safety and Health (NIOSH)
REL 400 ppm (980 mg/m³) Occupational Safety and Health Administration (OSHA)
REL 500 ppm (1225 mg/m³) Occupational Safety and Health Administration (OSHA)
REL TWA 400 ppm (980 mg/m3) ST 500 ppm (1225 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
IDLH 2000 ppm ; Based on 10% of the lower explosive limit. (NIOSH, 2024) CAMEO Chemicals
IDLH 2000.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
IDLH 2000 ppm Occupational Safety and Health Administration (OSHA)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Isopropyl alcohol properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Isopropyl alcohol boiling point

Property Value Conditions Source
Boiling point 82.3 °C (180.1 °F) at 760 mmHg HSDB
82.78 °C (181 °F) NIOSH
82.5 °C (180.5 °F) at 760 mmHg CAMEO

Isopropyl alcohol melting point

Property Value Conditions Source
Melting point -87.9 °C (-126.2 °F) HSDB
-88.33 °C (-127 °F) NIOSH
-88.5 °C (-127.3 °F) CAMEO

Isopropyl alcohol density

Property Value Conditions Source
Density 0.0008 g/cm³ HSDB
0.79 g/cm³ NIOSH
0.7851 g/cm³ at 25 °C HSDB

Isopropyl alcohol solubility

Property Value Conditions Source
Solubility Miscible with alcohol, ether, chloroform; insoluble in salt solution HSDB
Very soluble in benzene HSDB
Miscible with most organic solvents HSDB

Isopropyl alcohol vapor pressure

Property Value Conditions Source
Vapor pressure 33 mmHg NIOSH
33 mmHg at 20 °C CAMEO
45.4 mmHg at 25 °C HSDB

Isopropyl alcohol flash point

Property Value Conditions Source
Flash point 12 °C (53.6 °F) Closed cup HSDB
23.89 °C (75 °F) HSDB
11.67 °C (53 °F) NIOSH

Isopropyl alcohol autoignition temperature

Property Value Conditions Source
Autoignition temperature 399 °C (750.2 °F) HSDB
398.89 °C (750 °F) CAMEO
456 °C (852.8 °F) ICSC

Isopropyl alcohol lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 2 % by volume NIOSH

Isopropyl alcohol upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 12 % by volume CAMEO
12.7 % by volume at 93.33 °C HSDB

Isopropyl alcohol vapor density

Property Value Conditions Source
Vapor density 2.1 (air = 1) HSDB
2.07 (air = 1) CAMEO

Isopropyl alcohol odor threshold

Property Value Conditions Source
Odor threshold 90 mg/cu m HSDB
... MIN CONCN WITH IDENTIFIABLE ODOR ... IS 200 PPM. HSDB
Odor threshold 7.84 mg/cu m (low) 490 mg/cu m (high). HSDB

Isopropyl alcohol critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 235.15 °C (455.3 °F) HSDB

Isopropyl alcohol corrosivity

Property Value Conditions Source
Corrosivity Isopropyl alcohol will attack some forms of plastics, rubber, and coatings. HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Isopropyl alcohol fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Isopropyl alcohol fire potential

A very dangerous fire hazard when exposed to heat, flame or oxidizers.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Isopropyl alcohol storage and handling

Isopropyl alcohol reactive group

CAMEO Chemicals places Isopropyl alcohol in the reactive group Alcohols and Polyols. Compatibility with other chemicals is worked out from the group, not from the individual substance — which is why two substances you have never seen react can still be flagged as a pair that must be separated.

A reactive group is a CAMEO Chemicals (US NOAA) grouping, not a GHS hazard class: it has no code, no category and no legal force. It is what the storage compatibility matrix on this site computes from.

Isopropyl alcohol peroxide formation

B*: Compounds that form peroxides on concentration (distillation/evaporation)

Source: Lab and Research Safety, University of Minnesota

Isopropyl alcohol safe storage

Fireproof. Separated from strong oxidants. Cool. Well closed.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Isopropyl alcohol storage conditions

Keep container tightly closed in a dry and well-ventilated place. Store at room temperature in the original container. Sensitive to light. Store in light-resistant containers. Keep away from heat and sources of ignition. Store in a segrated and approved area. Store away from incompatible materials. /Isopropyl Alcohol, Reagent, ACS/

Source: Hazardous Substances Data Bank (HSDB)

Isopropyl alcohol incompatible materials

During distillation of 2-propanol recovered from the reduction of crotonaldehyde with aluminium isopropoxide, a violent explosion occurred. This was attributed either to peroxidized diisopropyl ether (a possible by-product) or to peroxidized crotonaldehyde.

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check Isopropyl alcohol in the storage compatibility matrix →

11 · Transport

Isopropyl alcohol UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Isopropyl alcohol under UN 1219 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
ISOPROPANOL (ISOPROPYL ALCOHOL) 3 F1 II
  • ADR label model 3 — Flammable liquid
3

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 3 is “Flammable liquids” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Isopropanol or Isopropyl alcohol 3 II
  • US DOT FLAMMABLE LIQUID label (§172.419)
3

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 3 is “Flammable and combustible liquid” (49 CFR 173.2).

Full UN 1219 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

Isopropyl alcohol — frequently asked questions

What is the CAS number of Isopropyl alcohol?

The CAS number of Isopropyl alcohol is 67-63-0. Its EC number is 200-661-7.

What is the chemical formula of Isopropyl alcohol?

The molecular formula of Isopropyl alcohol is C3H8O and its molecular weight is 60.1 g/mol.

What does a Isopropyl alcohol label have to show?

Under CLP Annex VI the label for Isopropyl alcohol carries the pictograms Flame and Exclamation mark and the signal word is Danger.

Is Isopropyl alcohol flammable?

Yes. CLP Annex VI assigns Isopropyl alcohol H225 — highly flammable liquid and vapour. The flash point reported for it is 12 °C (53.6 °F), Closed cup (HSDB).

Is Isopropyl alcohol a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Isopropyl alcohol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.

What is the exposure limit for Isopropyl alcohol?

The US occupational exposure limit reported for Isopropyl alcohol is 400.0 [ppm] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Isopropyl alcohol?

The boiling point reported for Isopropyl alcohol is 82.3 °C (180.1 °F), at 760 mmHg (HSDB).

What is the melting point of Isopropyl alcohol?

The melting point reported for Isopropyl alcohol is -87.9 °C (-126.2 °F) (HSDB).

How should Isopropyl alcohol be stored?

CLP Annex VI assigns Isopropyl alcohol the storage statement P403. Keep container tightly closed in a dry and well-ventilated place. Store at room temperature in the original container. Sensitive to light. Store in light-resistant containers. Keep away from heat and sources of ignition. Store in a segrated and approved area. Store away from incompatible materials. /Isopropyl Alcohol, Reagent, ACS/ (Hazardous Substances Data Bank (HSDB))

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