Substance profile
Mephosfolan
Mephosfolan is a colorless liquid.
01 · Identification
What Mephosfolan is
Mephosfolan is a colorless liquid. Its molecular formula is C8H16NO3PS2 and its molecular weight is 269.3 g/mol. It boils at 410 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Mephosfolan identifiers and molecular data
Mephosfolan CAS number and EC number
Mephosfolan molecular formula and molecular weight
Other names for Mephosfolan
- mephosfolan (ISO)
- diethyl 4-methyl-1,3-dithiolan-2-ylidenephosphoramidate
03 · GHS classification
Mephosfolan hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Mephosfolan pictograms and signal word
Mephosfolan hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 1 or 2 | H310 | GHS06 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 2 | H411 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Mephosfolan hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H310 | Fatal in contact with skin. |
| H300 | Fatal if swallowed. |
| H411 | Toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Mephosfolan. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Mephosfolan
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Mephosfolan issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Mephosfolan precautionary statements
CLP Annex VI assigns 10 precautionary statements to Mephosfolan. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Mephosfolan name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | мефосфолан (ISO) диетилов 4-метил-1,3-дитиолан-2-илиденфосфорамидат |
| Spanish español | Mefosfolan (ISO) 4-metil-1,3-ditiolan-2-ilidenfosforamidato de dietilo |
| Czech čeština | mefosfolan (ISO) diethyl-[ N -(4-methyl-2 H -1,3-dithiolan-2-yliden)fosforamidát] |
| Danish dansk | mephosfolan (ISO) diethyl-4-methyl-1,3-dithiolan-2-ylidenphosphoramidat |
| German Deutsch | Mephosfolan (ISO) Diethyl-4-methyl-1,3-dithiolan-2-ylidenphosphoramidat |
| Estonian eesti | mefosfolaan (ISO) dietüül-4-metüül-1,3-ditiolaan-2-ülideenfosforamidaat |
| Greek ελληνικά | mephosfolan (μεφωσφαλάνη) (ISO) 4-μεθυλο-1,3-διθειολαν-2-υλιδενοφωσφοραμιδικός διαιθυλεστέρας |
| English English | mephosfolan (ISO) diethyl 4-methyl-1,3-dithiolan-2-ylidenephosphoramidate |
| French français | méphospholan (ISO) phosphoramidate de diéthyle et de 4-méthyl-1,3-dithiolan-2-ylidène |
| Croatian hrvatski | mefosfolan (ISO) dietil-4-metil-1,3-ditiolan-2-ilidenfosforamidat |
| Italian italiano | mefosfolan (ISO) 4-metil-1,3-ditiolan-2-ilidenfosforammidato di dietile |
| Latvian latviešu | mefosfolāns (ISO) dietil-4-metil-1,3-ditiolān-2-ilidēnfosforamidāts |
| Lithuanian lietuvių | mefosfolanas (ISO) dietil-4-metil-1,3-ditiolan-2-ilidenamidofosfatas |
| Hungarian magyar | mefoszfolán (ISO) dietil-4-metil-1,3-ditiolan-2- ilidén-foszforamidát |
| Maltese Malti | mefosfolan (ISO) 4-metil-1,3-ditijolan-2-ilidenefosforammidat tad-dietil |
| Dutch Nederlands | mefosfolan (ISO) diëthyl-4-methyl-1,3-dithiolaan-2-ylideenfosforamidaat |
| Polish polski | mefosfolan (ISO) N -(4-metylo-1,3-ditiolan-2-ylideno)amidofosforan dietylu |
| Portuguese português | mefosfolão (ISO) 4-metil-1,3-ditiolan-2-ilidenofosforamidato de dietilo |
| Romanian română | mefosfolan (ISO) fosforamidat de dietil 4-metil-1,3-ditiolan-2- iliden |
| Slovak slovenčina | mefosfolán (ISO) dietyl-(4-metyl-1,3-ditiolán-2-ylidén)fosforamidát |
| Slovenian slovenščina | mefosfolan (ISO) dietil 4-metil-1,3-ditiolan-2-ilidenfosforamidat |
| Finnish suomi | mefosfolaani (ISO) dietyyli-4-metyyli-1,3-ditiolan-2-ylideenifosforoamidaatti |
| Swedish svenska | mefosfolan (ISO) dietyl-4-metyl-1,3-ditiolan-2-ylidenfosforamidat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Mephosfolan GHS label elements
Everything CLP Annex VI fixes for Mephosfolan, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Mephosfolan
- Fatal in contact with skin.
- Fatal if swallowed.
- Toxic to aquatic life with long lasting effects.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- Immediately call a POISON CENTER/doctor/…
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Mephosfolan in the GHS label constructor →
07 · Health hazards
Mephosfolan health hazards and exposure limits
Mephosfolan hazard summary
A highly toxic cholinesterase inhibitor; [CAMEO] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Mephosfolan properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Mephosfolan boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 410 °C (770 °F) | at 760 mmHg | DOE PAC |
| 120 °C (248 °F) | at 0.001 mmHg (reduced pressure) | HSDB |
Mephosfolan density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.539 g/cm³ | at 26 °C | HSDB |
Mephosfolan solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Soluble in acetone, xylene, benzene, ethanol and toluene, moderately soluble in water. | HSDB | |
| Solubility in water at 25 °C: 57 g/kg. | at 25 °C | HSDB |
Mephosfolan vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 1e-10 mmHg | at 25 °C | DOE PAC |
| 0.0000318 mmHg | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Mephosfolan storage and handling
Mephosfolan reactivity
When heated to decomposition, MEPHOSFOLAN emits very toxic fumes of nitrogen oxides, phosphorus oxides and sulfur oxides. Stable at neutral pH. Hydrolyzed by acid or alkali. [EPA, 1998]. Organophosphates, such as MEPHOSFOLAN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Mephosfolan in the storage compatibility matrix →
10 · Questions
Mephosfolan — frequently asked questions
What is the CAS number of Mephosfolan?
The CAS number of Mephosfolan is 950-10-7. Its EC number is 213-447-3.
What is the chemical formula of Mephosfolan?
The molecular formula of Mephosfolan is C8H16NO3PS2 and its molecular weight is 269.3 g/mol.
What does a Mephosfolan label have to show?
Under CLP Annex VI the label for Mephosfolan carries the pictograms Skull and crossbones and Environment and the signal word is Danger.
Is Mephosfolan flammable?
CLP Annex VI assigns Mephosfolan no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Mephosfolan a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Mephosfolan. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Mephosfolan?
The boiling point reported for Mephosfolan is 410 °C (770 °F), at 760 mmHg (DOE PAC).
Nearby
Substances next to Mephosfolan
Keep going: substances starting with M, or search the whole database by name, CAS number, pictogram or signal word.