Substance profile
Permethrin
Permethrin is colorless crystals to a viscous liquid; Color, white to pale yellow.
01 · Identification
What Permethrin is
Permethrin is colorless crystals to a viscous liquid; Color, white to pale yellow. Its molecular formula is C21H20Cl2O3 and its molecular weight is 391.3 g/mol. It boils at 290 °C, melts at 64 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
Permethrin identifiers and molecular data
Permethrin CAS number and EC number
Permethrin molecular formula and molecular weight
Other names for Permethrin
- permethrin (ISO)
- m-phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
03 · GHS classification
Permethrin hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Permethrin pictograms and signal word
Permethrin hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 4 | H332 | GHS07 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Permethrin hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H332 | Harmful if inhaled. |
| H302 | Harmful if swallowed. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Permethrin. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Permethrin
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Permethrin issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Permethrin precautionary statements
CLP Annex VI assigns 15 precautionary statements to Permethrin. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Permethrin name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | перметрин (ISO) m -феноксибензилов 2,2-диметил-3-(2,2-дихлоровинил)циклопропанкарбоксилат |
| Spanish español | Permetrina (ISO) 3-(2,2-diclorovinil)-2,2-dimetilciclopropanocarboxilato de m -fenoxibencilo |
| Czech čeština | permethrin (ISO) 3-fenoxybenzyl-[3-(2,2-dichlorvinyl)-2,2-dimethylcyklopropan-1-karboxylát] |
| Danish dansk | permethrin (ISO) m -phenoxybenzyl 3-(2,2-dichorovinyl)-2,2-dimethylcyclopropancarboxylat |
| German Deutsch | Permethrin (ISO) m -Phenoxybenzyl 3-(2,2-dichlorvinyl)-2,2-dimethylcyclopropancarboxylat |
| Estonian eesti | permetriin (ISO) m -fenoksübensüül-3-(2,2-diklorovinüül)-2,2-dimetüültsüklopropaankarboksülaat |
| Greek ελληνικά | permethrin (περμεθρίνη) (ISO) 3-(2,2-διχλωροβινυλο)-2,2-διμεθυλοκυκλοπροπανοκαρβοξυλικός m -φαινοξυβενζυλεστέρας |
| English English | permethrin (ISO) m -phenoxybenzyl 3-(2,2-dichorovinyl)-2,2-dimethylcyclopro panecarboxylate |
| French français | perméthrine (ISO) 3-(2,2-dichorovinyl)-2,2-diméthylcyclopropanecarboxylate de m -phénoxybenzyle |
| Croatian hrvatski | permetrin (ISO) m -fenoksibenzil 3-(2,2-diklorvinil)-2,2-dimetilciklopropankarboksilat |
| Italian italiano | permetrina (ISO) 3-(2,2-diclorovinil)-2,2-dimetilciclopropancarbossilato di m -fenossibenzile |
| Latvian latviešu | permetrīns (ISO) m -fenoksibenzil-3-(2,2-dihlorvinil)-2,2-dimetilciklopropānkarboksilāts |
| Lithuanian lietuvių | permetrinas (ISO) m -fenoksibenzil-3-(2,2-dichlorvinil)-2,2-dimetilciklopropankarboksilatas |
| Hungarian magyar | permetrin (ISO) m-fenoxibenzil-3-(2,2-diklórvinil)-2,2-dimetilciklopropánkarboxilát |
| Maltese Malti | permetrina (ISO) 3-(2,2-dikorovinil)-2,2-dimetilċiklopro-pankarbossilat ta’ m -fenossibenżil |
| Dutch Nederlands | permethrin (ISO) m -fenoxybenzyl-3-(2,2-dichloorvinyl)-2,2-dimethylcyclopropaancarboxylaat |
| Polish polski | permetryna (ISO) (1 RS )- cis , trans -3-(2,2-dichlorowinylo)-2,2-dimetylocyklopropanokarboksylan 3-fenoksybenzylu |
| Portuguese português | permetrina (ISO) 3-(2,2-diclorovinil)-2,2-dimetilciclopropanocarboxilato de m -fenoxibenzilo |
| Romanian română | permetrin (ISO) m -fenoxibenzil 3-(2,2-diclorovinil)-2,2-dimetilciclopropan-carboxilat |
| Slovak slovenčina | permetrín (ISO) O -(3-fenoxybenzyl)-3-(2,2-dichlórvinyl)-2,2-dimetylcyklopropánkarboxylát |
| Slovenian slovenščina | permetrin (ISO) m -fenoksibenzil 3-(2,2-diklorovinil)-2,2-dimetilciklopropankarboksilat |
| Finnish suomi | m -fenoksibentsyyli-3-(2,2-dikloorivinyyli)-2,2-dimetyylisyklopropaanikarboksylaatti permetriini (ISO) |
| Swedish svenska | permetrin (ISO) m -fenoxibensyl-3-(2,2-diklorvinyl)-2,2-dimetylcyklopropankarboxylat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Permethrin GHS label elements
Everything CLP Annex VI fixes for Permethrin, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Permethrin
- Harmful if inhaled.
- Harmful if swallowed.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF INHALED:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Rinse mouth.
- If skin irritation or rash occurs:
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Permethrin in the GHS label constructor →
07 · Health hazards
Permethrin health hazards and exposure limits
Permethrin hazard summary
A skin, eye, and respiratory tract irritant; [ICSC] May be a skin sensitizer; [eChemPortal: ESIS] May cause irritation; May cause skin sensitization; Targets the CNS in high-dose animal studies; [MSDSonline] Rapidly metabolized; Does not accumulate in body; Causes hyperactivity and tremors in high-dose feeding studies of experimental animals; Exposed workers complain of skin and eye irritation; No skin sensitization in animal studies; [INCHEM PDS: Permethrin] See Imiprothrin.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Permethrin carcinogenicity classification
The /Environmental Protection/ Agency classified permethrin as "Likely to be Carcinogenic to Humans" by the oral route. This classification was based on two reproducible benign tumor types (lung and liver) in the mouse, equivocal evidence of carcinogenicity in Long-Evans rats, and supporting structural activity relationships (SAR) information. For the purpose of risk characterization, a low dose extrapolation model (Q1*) was used. The Q1* is 9.6 x 10-3 (mg/kg/day)-1 and was derived from the female mouse lung (adenoma and/or carcinoma) tumors
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Permethrin properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Permethrin boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 290 °C (554 °F) | above this value, at 760 mmHg | HSDB |
| 200 °C (392 °F) | at 0.1 mmHg (reduced pressure) | HSDB | |
| 220 °C (428 °F) | at 0.05 mmHg (reduced pressure) | DrugBank |
Permethrin melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 64 °C (147.2 °F) | range, midpoint shown | HSDB |
| 36.5 °C (97.7 °F) | range, midpoint shown | ICSC | |
| 20 °C (68 °F) | below this value, OECD Method 102 | HSDB |
Permethrin density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.2 g/cm³ | ICSC | |
| 1.23 g/cm³ | range, midpoint shown, at 20 °C | HSDB |
Permethrin solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | In water, 0.0111 mg/L at 20 °C, pH 7.0-9.3 (OECD Method 105) | at 20 °C | HSDB |
| In water, 6.00X10-3 mg/L (pH 7, 20 °C); cis-isomers 0.20 mg/L (25 °C); trans-isomers 0.13 mg/L (25 °C) | at 20 °C | HSDB | |
| In xylene and hexane >1000, methanol 258 (all in g/kg at 25 °C) | at 25 °C | HSDB |
Permethrin vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 21.7518 mmHg | at 25 °C | HSDB |
| 5.18e-8 mmHg | at 25 °C | HSDB | |
| 2e-8 mmHg | Haz-Map |
Permethrin corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | Does not corrode aluminum | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Permethrin storage and handling
Permethrin safe storage
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Permethrin reactivity
A pyrethroid derivative.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Permethrin in the storage compatibility matrix →
10 · Questions
Permethrin — frequently asked questions
What is the CAS number of Permethrin?
The CAS number of Permethrin is 52645-53-1. Its EC number is 258-067-9.
What is the chemical formula of Permethrin?
The molecular formula of Permethrin is C21H20Cl2O3 and its molecular weight is 391.3 g/mol.
What does a Permethrin label have to show?
Under CLP Annex VI the label for Permethrin carries the pictograms Exclamation mark and Environment and the signal word is Warning.
Is Permethrin flammable?
CLP Annex VI assigns Permethrin no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Permethrin a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Permethrin. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.
What is the boiling point of Permethrin?
The boiling point reported for Permethrin is 290 °C (554 °F), above this value, at 760 mmHg (HSDB).
What is the melting point of Permethrin?
The melting point reported for Permethrin is 64 °C (147.2 °F), range, midpoint shown (HSDB).
Nearby
Substances next to Permethrin
Keep going: substances starting with P, or search the whole database by name, CAS number, pictogram or signal word.