Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Salicylic Acid

Salicylic Acid is white crystals, fine needles, or fluffy white crystalline powder and is odorless.

CAS 69-72-7 C7H6O3 138.12 g/mol Danger

01 · Identification

What Salicylic Acid is

Salicylic Acid is white crystals, fine needles, or fluffy white crystalline powder and is odorless. Its molecular formula is C7H6O3 and its molecular weight is 138.12 g/mol. It boils at 256 °C, melts at 159 °C, is soluble in water.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Salicylic Acid identifiers and molecular data

Salicylic Acid CAS number and EC number

CAS number69-72-7
EC number200-712-3
Index number (CLP Annex VI)607-732-00-5

Salicylic Acid molecular formula and molecular weight

Molecular formulaC7H6O3
Molecular weight138.12 g/mol

03 · GHS classification

Salicylic Acid hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Salicylic Acid pictograms and signal word

Signal wordDanger

Salicylic Acid hazard class and category

GHS hazard classes Salicylic Acid falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 1 H318 GHS05

Salicylic Acid hazard statements (H-codes)

Hazard statements assigned to Salicylic Acid
CodeHazard statement
H361d Suspected of damaging the unborn child.
H302 Harmful if swallowed.
H318 Causes serious eye damage.

This page lists only the codes assigned to Salicylic Acid. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Salicylic Acid

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Salicylic Acid issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Salicylic Acid precautionary statements

CLP Annex VI assigns 8 precautionary statements to Salicylic Acid. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Salicylic Acid name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български салицилова киселина
Spanish español Ácido salicílico
Czech čeština kyselina salicylová
Danish dansk salicylsyre
German Deutsch Salicylsäure
Estonian eesti salitsüülhape
Greek ελληνικά σαλικυλικό οξύ
English English salicylic acid
French français acide salicylique
Croatian hrvatski salicilna kiselina
Italian italiano Acido salicilico
Latvian latviešu salicilskābe
Lithuanian lietuvių salicilo rūgštis
Hungarian magyar szalicilsav
Maltese Malti aċidu saliċiliku
Dutch Nederlands salicylzuur
Polish polski kwas salicylowy
Portuguese português ácido salicílico
Romanian română acid salicilic
Slovak slovenčina kyselina salicylová
Slovenian slovenščina salicilna kislina
Finnish suomi salisyylihappo
Swedish svenska salicylsyra

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Salicylic Acid GHS label elements

Everything CLP Annex VI fixes for Salicylic Acid, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS07 Exclamation mark pictogramGHS05 Corrosion pictogram

Danger

Salicylic Acid

  • Suspected of damaging the unborn child.
  • Harmful if swallowed.
  • Causes serious eye damage.
  • Do not eat, drink or smoke when using this product.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF IN EYES:
  • Immediately call a POISON CENTER/doctor/
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Rinse mouth.
  • Remove contact lenses, if present and easy to do. Continue rinsing.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Salicylic Acid in the GHS label constructor →

07 · Health hazards

Salicylic Acid health hazards and exposure limits

Salicylic Acid hazard summary

An eye irritant; [CAMEO] Symptoms of salicylism after an acute overdose include ringing in the ears, confusion, hyperventilation, vomiting, and in severe cases, seizure and coma; Topical salicylic acid is keratolytic in concentrations greater than 3%; [HSDB] See Acetylsalicylic acid.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Salicylic Acid carcinogenicity classification

Studied by the US National Toxicology Program: TR-524: Photocarcinogenesis Study of Glycolic Acid and Salicylic Acid (CASRNs 79-14-1 and 69-72-7) in SKH-1 Mice (Simulated Solar Light and Topical Application Studies) (2007 )

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

Salicylic Acid properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Salicylic Acid boiling point

Property Value Conditions Source
Boiling point 256 °C (492.8 °F) sublimes, sublimes ICSC
211 °C (411.8 °F) at 20 mmHg (reduced pressure) HSDB

Salicylic Acid melting point

Property Value Conditions Source
Melting point 159 °C (318.2 °F) HSDB
157.22 °C (315 °F) CAMEO

Salicylic Acid density

Property Value Conditions Source
Density 1.4 g/cm³ ICSC
1.443 g/cm³ at 20 °C HSDB
1.44 g/cm³ at 20 °C CAMEO

Salicylic Acid solubility

Property Value Conditions Source
Solubility Soluble in oil of turpentine, alcohol, ether HSDB
SLIGHTLY SOL IN TOLUENE HSDB

Salicylic Acid vapor pressure

Property Value Conditions Source
Vapor pressure 0.000082 mmHg at 25 °C HSDB
0.00015 mmHg at 25 °C ICSC
0.000082 mmHg Haz-Map

Salicylic Acid flash point

Property Value Conditions Source
Flash point 157.22 °C (315 °F) HSDB
157 °C (314.6 °F) ICSC

Salicylic Acid autoignition temperature

Property Value Conditions Source
Autoignition temperature 540 °C (1004 °F) HSDB
570 °C (1058 °F) ICSC

Salicylic Acid lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 1.1 % by volume at 200 °C HSDB
DUST IS EXPLOSIVE IN AIR ... . HSDB

Salicylic Acid vapor density

Property Value Conditions Source
Vapor density 4.8 (air = 1) HSDB

Salicylic Acid corrosivity

Property Value Conditions Source
Corrosivity Non-corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Salicylic Acid fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Salicylic Acid fire potential

SLIGHT WHEN EXPOSED TO HEAT OF FLAME; CAN REACT WITH OXIDIZING MATERIALS

Source: Hazardous Substances Data Bank (HSDB)

Solubility

Solubility (weight percent): carbon tetrachloride 0.262 (25 °C); benzene 0.775 (25 °C); propanol 27.36 (21 °C); absolute ethanol 34.87 (21 °C); acetone 396 (23 °C)

Source: HSDB

10 · Handling and storage

Salicylic Acid storage and handling

Salicylic Acid safe storage

Separated from incompatible materials. See Chemical Dangers.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Salicylic Acid storage conditions

Salicylic acid should be stored in well-closed containers. Salicylic acid collodion should be stored in tight containers at 15-30 °C. Because the collodion is flammable, it should not be stored near heat or an open flame. Salicylic acid plaster should be stored in well-closed containers, preferably at 15-30 °C. The Trans-Ver-Sal plaster should be stored at a temperature less than 37.8 °C.

Source: Hazardous Substances Data Bank (HSDB)

Salicylic Acid incompatible materials

Incompatability: Iron salts, spirit nitrous ether, lead acetate, iodine.

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check Salicylic Acid in the storage compatibility matrix →

11 · Questions

Salicylic Acid — frequently asked questions

What is the CAS number of Salicylic Acid?

The CAS number of Salicylic Acid is 69-72-7. Its EC number is 200-712-3.

What is the chemical formula of Salicylic Acid?

The molecular formula of Salicylic Acid is C7H6O3 and its molecular weight is 138.12 g/mol.

What does a Salicylic Acid label have to show?

Under CLP Annex VI the label for Salicylic Acid carries the pictograms Health hazard, Exclamation mark and Corrosion and the signal word is Danger.

Is Salicylic Acid flammable?

CLP Annex VI assigns Salicylic Acid no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 157.22 °C (315 °F) (HSDB).

Is Salicylic Acid a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Salicylic Acid. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of Salicylic Acid?

The boiling point reported for Salicylic Acid is 256 °C (492.8 °F), sublimes, sublimes (ICSC).

What is the melting point of Salicylic Acid?

The melting point reported for Salicylic Acid is 159 °C (318.2 °F) (HSDB).

How should Salicylic Acid be stored?

Salicylic acid should be stored in well-closed containers. Salicylic acid collodion should be stored in tight containers at 15-30 °C. Because the collodion is flammable, it should not be stored near heat or an open flame. Salicylic acid plaster should be stored in well-closed containers, preferably at 15-30 °C. The Trans-Ver-Sal plaster should be stored at a temperature less than 37.8 °C. (Hazardous Substances Data Bank (HSDB))

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