Substance profile
TEPP (ISO)
TEPP (ISO) is a mobile liquid with an agreeable odor.
01 · Identification
What TEPP (ISO) is
TEPP (ISO) is a mobile liquid with an agreeable odor. Its molecular formula is C8H20O7P2 and its molecular weight is 290.19 g/mol. It boils at 310 °C, melts at 0 °C, is miscible with water.
Under the GHS it carries the signal word Danger.
02 · Identifiers
TEPP (ISO) identifiers and molecular data
TEPP (ISO) CAS number and EC number
TEPP (ISO) molecular formula and molecular weight
Other names for TEPP (ISO)
- tetraethyl pyrophosphate
03 · GHS classification
TEPP (ISO) hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
TEPP (ISO) pictograms and signal word
TEPP (ISO) hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 1 or 2 | H310 | GHS06 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
TEPP (ISO) hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H310 | Fatal in contact with skin. |
| H300 | Fatal if swallowed. |
| H400 | Very toxic to aquatic life. |
This page lists only the codes assigned to TEPP (ISO). The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for TEPP (ISO)
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of TEPP (ISO) issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
TEPP (ISO) precautionary statements
CLP Annex VI assigns 10 precautionary statements to TEPP (ISO). They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
TEPP (ISO) name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | TEPP (ISO) тетраетилов пирофосфат |
| Spanish español | TEPP (ISO) pirofosfato de tetraetilo |
| Czech čeština | TEPP (ISO) tetraethyl-difosfát |
| Danish dansk | TEPP (ISO) tetraethylpyrophosphat |
| German Deutsch | TEPP (ISO) Tetraethylpyrophosphat |
| Estonian eesti | TEPP (ISO) tetraetüülpürofosfaat |
| Greek ελληνικά | TEPP (ISO) πυροφωσφoρικός τετρααιθυλεστέρας |
| English English | TEPP (ISO) tetraethyl pyrophosphate |
| French français | TEPP (ISO) pyrophosphate de tétraéthyle |
| Croatian hrvatski | TEPP (ISO) tetraetil-pirofosfat |
| Italian italiano | TEPP (ISO) pirofosfato di tetraetile |
| Latvian latviešu | TEPP (ISO) tetraetilpirofosfāts |
| Lithuanian lietuvių | TEPP (ISO) tetraetilpirofosfatas |
| Hungarian magyar | TEPP (ISO) tetraetil-pirofoszfát |
| Maltese Malti | TEPP (ISO) pirofosfat tat-tetraetil |
| Dutch Nederlands | TEPP (ISO) tetraëthylpyrofosfaat |
| Polish polski | TEPP (ISO) pirofosforan tetraetyludifosforan(V) tetraetylu |
| Portuguese português | TEPP (ISO) pirofosfato de tetraetilo |
| Romanian română | TEPP (ISO) pirofosfat de tetraetil |
| Slovak slovenčina | TEPP (ISO) tetraetyl-difosfát |
| Slovenian slovenščina | TEPP (ISO) tetraetil pirofosfat |
| Finnish suomi | TEPP (ISO) tetraetyylipyrofosfaatti |
| Swedish svenska | TEPP (ISO) tetraetylpyrofosfat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
TEPP (ISO) GHS label elements
Everything CLP Annex VI fixes for TEPP (ISO), laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
TEPP (ISO)
- Fatal in contact with skin.
- Fatal if swallowed.
- Very toxic to aquatic life.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- Immediately call a POISON CENTER/doctor/…
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open TEPP (ISO) in the GHS label constructor →
07 · Health hazards
TEPP (ISO) health hazards and exposure limits
TEPP (ISO) hazard summary
Many deaths have been reported, most after suicidal ingestion. Several cases of severe poisoning and death have been reported after spills in which workers clothing was contaminated. [ACGIH] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
TEPP (ISO) occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | 0.05 [mg/m3] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| PEL | 0.05 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| PEL | TWA 0.05 mg/m3 [skin] | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | 0.05 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| REL | TWA 0.05 mg/m3 [skin] | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | 5 mg/m3 (NIOSH, 2024) | CAMEO Chemicals |
| IDLH | 5.0 [mg/m3] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| IDLH | 5 mg/cu m | Hazardous Substances Data Bank (HSDB) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
TEPP (ISO) properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
TEPP (ISO) boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 310 °C (590 °F) | at 760 mmHg | DOE PAC |
| 82 °C (179.6 °F) | at 0.05 mmHg (reduced pressure) | HSDB | |
| 137.78 °C (280 °F) | at 2.3 mmHg (reduced pressure) | CAMEO |
TEPP (ISO) melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 0 °C (32 °F) | NIOSH |
TEPP (ISO) density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.19 g/cm³ | NIOSH | |
| 1.185 g/cm³ | at 20 °C | HSDB | |
| 1.2 g/cm³ | at 25 °C | HSDB |
TEPP (ISO) solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Miscible with glycerol, ethylene glycol, toluene, propylene glycol, acetone, methanol, benzene, carbon tetrachloride, xylene, ethanol, chloroform | HSDB | |
| Miscible in water | HSDB | ||
| Miscible (decomposes) (NTP, 1992) | decomposes | CAMEO |
TEPP (ISO) vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.0002 mmHg | NIOSH | |
| 0.015 mmHg | at 20 °C | ICSC | |
| 0.00026 mmHg | at 25 °C | HSDB |
TEPP (ISO) flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 110 °C (230 °F) | above this value | ICSC |
TEPP (ISO) lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Noncombustible Liquid | NIOSH | |
| Not combustible. (EPA, 1998) | CAMEO |
TEPP (ISO) upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | Not combustible. (EPA, 1998) | CAMEO |
TEPP (ISO) vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 10 (air = 1) | ICSC |
TEPP (ISO) corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | TEPP will attack some forms of plastics, rubber, and coatings. | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
TEPP (ISO) storage and handling
TEPP (ISO) safe storage
Store only in original container. Separated from food and feedstuffs. Keep in a well-ventilated room. Dry. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
TEPP (ISO) storage conditions
It should be stored in moisture-proof containers in a cool well-ventilated area. Empty drums should be decontaminated; never re-use containers.
Source: Hazardous Substances Data Bank (HSDB)
TEPP (ISO) incompatible materials
Incompatibilities: ... it is incompatible with alkaline materials.
Source: Hazardous Substances Data Bank (HSDB)
TEPP (ISO) reactivity
TETRAETHYL PYROPHOSPHATE reacts slowly with water to form HPO3; corrosive to aluminum; slowly corrosive to copper, brass, zinc and tin; incompatible with strong oxidizers (NTP, 1992). Organophosphates, such as TETRAETHYL PYROPHOSPHATE, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check TEPP (ISO) in the storage compatibility matrix →
10 · Questions
TEPP (ISO) — frequently asked questions
What is the CAS number of TEPP (ISO)?
The CAS number of TEPP (ISO) is 107-49-3. Its EC number is 203-495-3.
What is the chemical formula of TEPP (ISO)?
The molecular formula of TEPP (ISO) is C8H20O7P2 and its molecular weight is 290.19 g/mol.
What does a TEPP (ISO) label have to show?
Under CLP Annex VI the label for TEPP (ISO) carries the pictograms Skull and crossbones and Environment and the signal word is Danger.
Is TEPP (ISO) flammable?
CLP Annex VI assigns TEPP (ISO) no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 110 °C (230 °F), above this value (ICSC).
Is TEPP (ISO) a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for TEPP (ISO). Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the exposure limit for TEPP (ISO)?
The US occupational exposure limit reported for TEPP (ISO) is 0.05 [mg/m3] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of TEPP (ISO)?
The boiling point reported for TEPP (ISO) is 310 °C (590 °F), at 760 mmHg (DOE PAC).
What is the melting point of TEPP (ISO)?
The melting point reported for TEPP (ISO) is 0 °C (32 °F) (NIOSH).
How should TEPP (ISO) be stored?
It should be stored in moisture-proof containers in a cool well-ventilated area. Empty drums should be decontaminated; never re-use containers. (Hazardous Substances Data Bank (HSDB))
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