Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Tetrahydrothiophene-1,1-dioxide

Tetrahydrothiophene-1,1-dioxide is a white or creamy white, crystalline powder and is odorless.

CAS 126-33-0 Warning

01 · Identification

What Tetrahydrothiophene-1,1-dioxid… is

Tetrahydrothiophene-1,1-dioxide is a white or creamy white, crystalline powder and is odorless. It boils at 285 °C, melts at 26.1 °C.

Under the GHS it carries the signal word Warning.

02 · Identifiers

Tetrahydrothiophene-1,1-dioxid… identifiers and molecular data

Tetrahydrothiophene-1,1-dioxid… CAS number and EC number

CAS number126-33-0
EC number204-783-1
Index number (CLP Annex VI)016-031-00-8

Other names for Tetrahydrothiophene-1,1-dioxid…

  • sulpholane

03 · GHS classification

Tetrahydrothiophene-1,1-dioxid… hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Tetrahydrothiophene-1,1-dioxid… pictograms and signal word

Signal wordWarning

Tetrahydrothiophene-1,1-dioxid… hazard class and category

GHS hazard classes Tetrahydrothiophene-1,1-di… falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07

Tetrahydrothiophene-1,1-dioxid… hazard statements (H-codes)

Hazard statements assigned to Tetrahydrothiophene-1,1-di…
CodeHazard statement
H302 Harmful if swallowed.

This page lists only the codes assigned to Tetrahydrothiophene-1,1-di…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Tetrahydrothiophene-1,1-di…

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Tetrahydrothiophene-1… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Tetrahydrothiophene-1,1-dioxid… precautionary statements

CLP Annex VI assigns 4 precautionary statements to Tetrahydrothiophene-1,1-di…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Prevention

What to do before and during handling so the hazard never happens.

Response

What to do once exposure, spillage or fire has already happened.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Tetrahydrothiophene-1,1-dioxid… name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български тетрахидротиофен-1,1-диоксид сулфолан
Spanish español 1,1-Dióxido de tetrahidrotiofeno sulfolano
Czech čeština tetrahydrothiofen-1,1-dioxid sulfolan
Danish dansk tetrahydrothiophen-1,1-dioxid sulfolan
German Deutsch Tetrahydrothiophen-1,1-dioxid Sulfolan
Estonian eesti tetrahüdrotiofeen-1,1-dioksiid sulfolaan
Greek ελληνικά 1,1-διοξείδιο του τετραϋδρoθειοφαινίου σουλφολάνιο
English English tetrahydrothiophene-1,1-dioxide sulpholane
French français 1,1-dioxyde de tétrahydrothiophène sulfolane
Croatian hrvatski tetrahidrotiofen-1,1-dioksid sulfolan
Italian italiano tetraidrotiofene 1,1-diossido
Latvian latviešu tetrahidrotiofēn-1,1-dioksīds sulfolans
Lithuanian lietuvių tetrahidrotiofeno 1,1-dioksidas sulfolanas
Hungarian magyar tetrahidrotiofén-1,1-dioxid szulfolán
Maltese Malti tetraidrotijofen-1,1-diossidu sulfolan
Dutch Nederlands tetrahydrothiofeen-1,1-dioxide sulfolaan
Polish polski 1,1-ditlenek tetrahydrotiofenu sulfolan1,1-dioksotetrahydrotiofensulfon tetrametylenu
Portuguese português 1,1-dióxido de tetra-hidrotiofeno sulfolano
Romanian română 1,1-dioxid de tetrahidrotiofen sulfolan
Slovak slovenčina tetrahydrotiofén-1,1-dioxid sulfolán
Slovenian slovenščina tetrahidrotiofen-1,1-dioksid sulfolan
Finnish suomi tetrahydrotiofeeni-1,1-dioksidi sulfolaani
Swedish svenska tetrahydrotiofen-1,1-dioxid sulfolan

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Tetrahydrothiophene-1,1-dioxid… GHS label elements

Everything CLP Annex VI fixes for Tetrahydrothiophene-1,1-di…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS07 Exclamation mark pictogram

Warning

Tetrahydrothiophene-1,1-dioxid…

  • Harmful if swallowed.
  • Do not eat, drink or smoke when using this product.
  • IF SWALLOWED:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Rinse mouth.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Tetrahydrothiophene-1,1-di… in the GHS label constructor →

07 · Health hazards

Tetrahydrothiophene-1,1-dioxid… health hazards and exposure limits

Tetrahydrothiophene-1,1-dioxid… hazard summary

Not irritating or sensitizing to rabbit skin; Mildly irritating to rabbit eyes; All rats convulsed during aerosolized exposure in lethal-concentration study; Convulsions observed in sub-chronic inhalation studies of dogs and monkeys and clonic-tonic convulsions noted in rats exposed by oral and parenteral routes; Intraperitoneal injection causes decreased metabolic rate and hypothermia in mice and rats; No evidence of mutagenicity; [HSDB] A mild eye irritant; [Alfa Aesar MSDS]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

Tetrahydrothiophene-1,1-dioxid… properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Tetrahydrothiophene-1,1-dioxid… boiling point

Property Value Conditions Source
Boiling point 285 °C (545 °F) HSDB
285 °C (545 °F) at 760 mmHg CAMEO

Tetrahydrothiophene-1,1-dioxid… melting point

Property Value Conditions Source
Melting point 26.11 °C (79 °F) CAMEO
27.6 °C (81.7 °F) range, midpoint shown HSDB

Tetrahydrothiophene-1,1-dioxid… density

Property Value Conditions Source
Density 1.261 g/cm³ at 25 °C DOE PAC
1.2606 g/cm³ at 30 °C HSDB
1.26 g/cm³ at 30 °C CAMEO

Tetrahydrothiophene-1,1-dioxid… solubility

Property Value Conditions Source
Solubility Freely soluble in alcohol, soluble in dilute mineral acids HSDB
Partially miscible with octanes, olefins, naphthenes; miscible with water, Acetone, toluene at 30 °C at 30 °C HSDB

Tetrahydrothiophene-1,1-dioxid… vapor pressure

Property Value Conditions Source
Vapor pressure 0.0062 mmHg at 27.6 °C, Extrapolated HSDB
0.0062 mmHg Haz-Map
Vapor pressure: 5 mm @ 118 °C at 118 °C HSDB

Tetrahydrothiophene-1,1-dioxid… flash point

Property Value Conditions Source
Flash point 177 °C (350.6 °F) HSDB
165.56 °C (330 °F) CAMEO

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Tetrahydrothiophene-1,1-di… fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Tetrahydrothiophene-1,1-dioxid… fire potential

Combustible when exposed to heat or flame.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Tetrahydrothiophene-1,1-dioxid… storage and handling

Tetrahydrothiophene-1,1-dioxid… incompatible materials

Nitronium tetrafluoroborate /is potentially explosive/ in sulfolane.

Source: Hazardous Substances Data Bank (HSDB)

Tetrahydrothiophene-1,1-dioxid… reactivity

Mixing SULFOLANE in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid and oleum [NFPA 1991]. With nitrating agents (nitronium tetrafluoroborate in sulfolane) very highly exothermic reactions are known to occur [J. Org. Chem., 1978, 43, 4677].

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Tetrahydrothiophene-1,1-d… in the storage compatibility matrix →

11 · Questions

Tetrahydrothiophene-1,1-dioxid… — frequently asked questions

What is the CAS number of Tetrahydrothiophene-1,1-dioxid…?

The CAS number of Tetrahydrothiophene-1,1-dioxid… is 126-33-0. Its EC number is 204-783-1.

What does a Tetrahydrothiophene-1,1-dioxid… label have to show?

Under CLP Annex VI the label for Tetrahydrothiophene-1,1-dioxid… carries the pictogram Exclamation mark and the signal word is Warning.

Is Tetrahydrothiophene-1,1-dioxid… flammable?

CLP Annex VI assigns Tetrahydrothiophene-1,1-dioxid… no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 177 °C (350.6 °F) (HSDB).

Is Tetrahydrothiophene-1,1-dioxid… a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Tetrahydrothiophene-1,1-dioxid…. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of Tetrahydrothiophene-1,1-dioxid…?

The boiling point reported for Tetrahydrothiophene-1,1-dioxid… is 285 °C (545 °F) (HSDB).

What is the melting point of Tetrahydrothiophene-1,1-dioxid…?

The melting point reported for Tetrahydrothiophene-1,1-dioxid… is 26.11 °C (79 °F) (CAMEO).

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