Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Thiofanox

Thiofanox is a colorless solid with a PUNGENT odor.

CAS 39196-18-4 Danger

01 · Identification

What Thiofanox is

Thiofanox is a colorless solid with a PUNGENT odor. It melts at 57 °C.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Thiofanox identifiers and molecular data

Thiofanox CAS number and EC number

CAS number39196-18-4
EC number254-346-4
Index number (CLP Annex VI)006-064-00-6

Other names for Thiofanox

  • thiofanox (ISO)
  • 3,3-dimethyl-1-(methylthio)butanone-O-(N-methylcarbamoyl)oxime

03 · GHS classification

Thiofanox hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Thiofanox pictograms and signal word

Signal wordDanger

Thiofanox hazard class and category

GHS hazard classes Thiofanox falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 1 or 2 H300 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 1 or 2 H310 GHS06
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Thiofanox hazard statements (H-codes)

Hazard statements assigned to Thiofanox
CodeHazard statement
H310 Fatal in contact with skin.
H300 Fatal if swallowed.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Thiofanox. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Thiofanox

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Thiofanox issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Thiofanox precautionary statements

CLP Annex VI assigns 10 precautionary statements to Thiofanox. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Thiofanox name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български тиофанокс (ISO) 3,3-диметил-1-(метилтио)бутанон- О -( N -метилкарбамоил)оксим
Spanish español Tiofanox (ISO) 3,3-dimetil-1-(metiltio)butanona- O -( N -metilcarbamoil)oxima
Czech čeština thiofanox (ISO) 3,3-dimethyl-1-(methylsulfanyl)butan-2-on- O -( N -methylkarbamoyl)oxim
Danish dansk thiofanox (ISO) 3,3-dimethyl-1-(methylthio)butanon- O- ( N- methylcarbamoyl)oxim
German Deutsch Thiofanox (ISO) 3,3-Dimethyl-1-(methylthio)butanon- O -( N -methylcarbamoyl)oxim
Estonian eesti tiofaanoks (ISO) 3,3-dimetüül-1-(metüültio)butanoon- O -( N -metüülkarbamoüül)oksiim
Greek ελληνικά thiofanox (θειοφανόξη) (ISO) 3,3-διμεθυλο-2-(μεθυλοθειο)βουτανον- O -( N -μεθυλοκαρβαμοϋλ)οξίμη
English English thiofanox (ISO) 3,3-dimethyl-1-(methylthio)butanone- O -( N -methylcarbamoyl)oxime
French français thiofanox (ISO) 3,3-diméthyl-1-(méthylthio)butanone- O -( N -méthylcarbamoyl)oxime
Croatian hrvatski tiofanoks (ISO) 3,3-dimetil-1-(metiltio)butanon- O -( N -metil-karbamoil)oksim
Italian italiano tiofanox (ISO) 3,3-dimetil-1-(metiltio)butanon- O -( N -metilcarbammoil)ossima
Latvian latviešu tiofanokss (ISO) 3,3-dimetil-1-(metiltio)butanon- O -( N -metilkarbamoil)oksīms
Lithuanian lietuvių tiofanoksas (ISO) 3,3-dimetil-1-(metiltio)butanon-O-(N-metilkarbamoil)oksimas
Hungarian magyar tiofanox (ISO) 3,3-dimetil-1-(metiltio)butanon- O -( N -metilkarbamoil)oxim
Maltese Malti tijofanoks (ISO) 3,3-dimetil-1-(metiltijo)butanone-O-(N-metilkarbamojl)ossim
Dutch Nederlands thiofanox (ISO) 3,3-dimethyl-1-(methylthio)butanon- O -( N -methylcarbamoyl)oxim
Polish polski tiofanoks (ISO) O-(metylokarbamoilo)oksym 3,3-dimetylo-1-(metylosulfanylo)-butan-2-onu
Portuguese português tiofanox (ISO) O -( N -metilcarbamoil)oxima de 3,3-dimetil-1-(metiltio)butanona
Romanian română tiofanox (ISO) 3,3-dimetil-1-(metiltio)butanon- O -( N -metilcarbamoil)oximă
Slovak slovenčina tiofanox (ISO) 3,3-dimetyl-1-(metylsulfanyl)butanón- O -( N -metylkarbamoyl)oxím
Slovenian slovenščina tiofanoks (ISO) 3,3-dimetil-1-(metiltio)butanon- O -( N -metilkarbamoil)oksim
Finnish suomi tiofanoksi (ISO) 3,3-dimetyyli-1-(metyylitio)butanoni- O -( N -metyylikarbamyyli)oksiimi
Swedish svenska tiofanox (ISO) 3,3-dimetyl-1-(metyltio)butanon- O -( N -metylkarbamoyl)oxim

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Thiofanox GHS label elements

Everything CLP Annex VI fixes for Thiofanox, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS09 Environment pictogram

Danger

Thiofanox

  • Fatal in contact with skin.
  • Fatal if swallowed.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not eat, drink or smoke when using this product.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • Immediately call a POISON CENTER/doctor/
  • Rinse mouth.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Thiofanox in the GHS label constructor →

07 · Health hazards

Thiofanox health hazards and exposure limits

Thiofanox hazard summary

NOEL in 90 day feeding studies with dogs and rats was 1 mg/kg/day; Symptoms of cholinesterase inhibition lasted 3-4 hours in rats at 4 mg/kg/day; [HSDB] A cholinesterase inhibitor; [CAMEO] See CARBAMATE INSECTICIDES.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

Thiofanox properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Thiofanox melting point

Property Value Conditions Source
Melting point 57 °C (134.6 °F) DOE PAC
57 °C (134.6 °F) range, midpoint shown HSDB

Thiofanox solubility

Property Value Conditions Source
Solubility 5.2 G/L WATER AT 22 °C at 22 °C HSDB
VERY SOL IN CHLORINATED & AROMATIC HYDROCARBONS, KETONES, INCLUDING APOLAR SOLVENTS; SPARINGLY SOL IN POLAR ALIPHATIC HYDROCARBONS. HSDB

Thiofanox vapor pressure

Property Value Conditions Source
Vapor pressure 0.00017 mmHg at 25 °C HSDB
0.00017 mmHg Haz-Map

Thiofanox lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) Non-flammable. (EPA, 1998) CAMEO

Thiofanox upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) Non-flammable. (EPA, 1998) CAMEO

Thiofanox corrosivity

Property Value Conditions Source
Corrosivity Non-corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Thiofanox storage and handling

Thiofanox reactivity

THIOFANOX is a thiocarbamate. Flammable gases are generated by the combination of thiocarbamates and dithiocarbamates with aldehydes, nitrides, and hydrides. Thiocarbamates and dithiocarbamates are incompatible with acids, peroxides, and acid halides.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Thiofanox in the storage compatibility matrix →

10 · Questions

Thiofanox — frequently asked questions

What is the CAS number of Thiofanox?

The CAS number of Thiofanox is 39196-18-4. Its EC number is 254-346-4.

What does a Thiofanox label have to show?

Under CLP Annex VI the label for Thiofanox carries the pictograms Skull and crossbones and Environment and the signal word is Danger.

Is Thiofanox flammable?

CLP Annex VI assigns Thiofanox no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Thiofanox a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Thiofanox. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the melting point of Thiofanox?

The melting point reported for Thiofanox is 57 °C (134.6 °F) (DOE PAC).

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