Substance profile
Zoxamide
Zoxamide is a white solid with a licorice-like odor.
01 · Identification
What Zoxamide is
Zoxamide is a white solid with a licorice-like odor. It melts at 159 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
Zoxamide identifiers and molecular data
Zoxamide CAS number and EC number
Other names for Zoxamide
- zoxamide (ISO)
- (RS)-3,5-dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-p-toluamide
03 · GHS classification
Zoxamide hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Zoxamide pictograms and signal word
Zoxamide hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Zoxamide hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Zoxamide. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Zoxamide
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Zoxamide issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Zoxamide precautionary statements
CLP Annex VI assigns 8 precautionary statements to Zoxamide. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Zoxamide name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | зоксамид (ISO) ( RS )- N -(1-етил-1-метил-2-оксо-3-хлоропропил)-3,5-дихлоро- p -толуамид |
| Spanish español | Zoxamida (ISO) ( RS )-3,5-dicloro- N -(3-cloro-1-etil-1-metil-2-oxopropil)- p- toluamida |
| Czech čeština | zoxamid (ISO) ( RS )-3,5-dichlor- N -(3-chlor-1-ethyl-1-methyl-2-oxopropyl)- p -toluamid |
| Danish dansk | zoxamid (ISO) ( RS )-3,5-dichlor- N- (3-chlor-1-ethyl-1-methyl-2-oxopropyl)- p -toluamid |
| German Deutsch | Zoxamid (ISO) ( RS )-3,5-Dichlor- N -(3-chlor-1- ethyl-1-methyl-2-oxopropyl)- p -toluamid |
| Estonian eesti | soksamiid (ISO) ( RS )-3,5-dikloro- N -(3-kloro-1-etüül-1-metüül-2-oksopropüül)- p- toluamiid |
| Greek ελληνικά | zoxamide (ζοξαμίδη) (ISO) ( RS )-3,5-διχλωρο- N -(3-χλωρο-1-αιθυλο-1-μεθυλ-2-οξοπροπυλο)- p -τολουαμίδιο |
| English English | zoxamide (ISO) ( RS )-3,5-dichloro- N -(3-chloro-1-ethyl-1-methyl-2-oxopropyl)- p- toluamide |
| French français | zoxamide (ISO) ( RS )-3,5-dichloro- N -(3-chloro-1-éthyl-1-méthyl-2-oxopropyl)- p- toluamide |
| Croatian hrvatski | zoksamid (ISO) ( RS )-3,5-diklor- N -(3-klor-1-etil-1-metil-2-oksopropil)- p- toluamid |
| Italian italiano | zoxamide (ISO) ( RS )-3,5-dicloro- N -(3-cloro-1-etil-1-metil-2-ossopropil)- p -toluammide |
| Latvian latviešu | zoksamīds (ISO) ( RS )-3,5-dihlor- N -(3-hlor-1-etil-1-metil-2-oksopropil)- p- toluamīds |
| Lithuanian lietuvių | zoksamidas (ISO) ( RS )-3,5-dichlor- N -(3-chlor-1-etil-1-metil-2-oksopropil)- p -toluamidas |
| Hungarian magyar | zoxamid (ISO) ( RS )-3,5-diklór- N -(3-klór-1-etil-1-metil-2-oxopropil)- p -toluamid |
| Maltese Malti | żossammid (ISO) ( RS )-3,5-dikloro- N -(3-kloro-1-etil-1-metil-2-ossopropil)- p- toluammid |
| Dutch Nederlands | zoxamide (ISO) ( RS )-3,5-dichloor- N -(3-chloor-1-ethyl-1-methyl-2-oxopropyl)- p -toluamide |
| Polish polski | zoksamid (ISO) ( RS )-3,5-dichloro- N -(3-chloro-1-etylo-1-metylo-2-oksopropylo)- p -toluamid |
| Portuguese português | zoxamida (ISO) ( RS )-3,5-dicloro- N -(3-cloro-1-etil-1-metil-2-oxopropil)- p -toluamida |
| Romanian română | zoxamidă (ISO) ( RS )-3,5-dicloro- N -(3-cloro-1-etil-1-metil-2-oxopropil)- p -toluamidă |
| Slovak slovenčina | zoxamid (ISO) ( RS )-3,5-dichlór- N -(1-chlór-3-metyl-2-oxopentán-3-yl)-4-metylbenzamid |
| Slovenian slovenščina | zoksamid (ISO) ( RS )-3,5-dikloro- N -(3-kloro-1-etil-1-metil-2-oksopropil)- p -toluamid |
| Finnish suomi | tsoksamidi (ISO) ( RS )-3,5-dikloori- N -(3-kloori-1-etyyli-1-metyyli-2-oksopropyyli)- p -toluamidi |
| Swedish svenska | zoxamid (ISO) ( RS )-3,5-diklor- N -(3-klor-1-etyl-1-metyl-2-oxopropyl)- p -toluamid |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Zoxamide GHS label elements
Everything CLP Annex VI fixes for Zoxamide, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Zoxamide
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- Get medical advice/attention.
- If skin irritation or rash occurs:
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Zoxamide in the GHS label constructor →
07 · Health hazards
Zoxamide health hazards and exposure limits
Zoxamide hazard summary
A strong skin sensitizer and potential cause of occupational asthma; Not a neurotoxin or reproductive toxin; Not likely to be a human carcinogen; [Reference #1] In high-dose animal experiments, causes liver changes and increase in liver weight; [RTECS] May cause moderate eye irritation and mild corneal injury; Organs affected in high-dose animal studies include liver and thyroid; [MSDSonline]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Zoxamide carcinogenicity classification
Cancer Classification: Not Likely to be Carcinogenic to Humans
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Zoxamide properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Zoxamide melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 159 °C (318.2 °F) | range, midpoint shown | HSDB |
Zoxamide density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.38 g/cm³ | at 20 °C | HSDB |
Zoxamide solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | In water, 0.681 mg/L at 20 °C | at 20 °C | HSDB |
| In acetone = 0.0557 mg/L at 25 °C | at 25 °C | HSDB |
Zoxamide vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 9.9e-8 mmHg | below this value, at 25 °C | HSDB |
| 1e-8 mmHg | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Zoxamide storage and handling
Zoxamide storage conditions
Keep container tightly closed in a dry and well-ventilated place.
Source: Hazardous Substances Data Bank (HSDB)
Zoxamide incompatible materials
Incompatible with strong acids and bases, reducing agents.
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check Zoxamide in the storage compatibility matrix →
10 · Questions
Zoxamide — frequently asked questions
What is the CAS number of Zoxamide?
The CAS number of Zoxamide is 156052-68-5.
What does a Zoxamide label have to show?
Under CLP Annex VI the label for Zoxamide carries the pictograms Exclamation mark and Environment and the signal word is Warning.
Is Zoxamide flammable?
CLP Annex VI assigns Zoxamide no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Zoxamide a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Zoxamide. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the melting point of Zoxamide?
The melting point reported for Zoxamide is 159 °C (318.2 °F), range, midpoint shown (HSDB).
How should Zoxamide be stored?
Keep container tightly closed in a dry and well-ventilated place. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Zoxamide
Keep going: substances starting with Z, or search the whole database by name, CAS number, pictogram or signal word.