Safety data sheet reference · CAS 302-01-2
Hydrazine SDS
also: hydrazine MSDS · safety data sheet · N2H4 · CAS 302-01-2 · EC 206-114-9
Official PDF from supplier
This page is a reference, not the legal document.
CAS number
302-01-2
EC number
206-114-9
CLP Annex VI index
007-008-00-3
Molecular formula
N2H4
§ 02 · Hazards identification
Hydrazine harmonised EU classification
CLP Annex VI · Index 007-008-00-3. A supplier SDS may add self-classified hazards — this is the legal minimum.
Precautionary statements
Codes ending in a colon introduce the action that follows — on a label they are printed as combined statements, such as P305+P351+P338.
§ 03 · Composition and identifiers
Hydrazine molecular structure
Hydrazine is a molecular compound. The skeletal formula below is drawn from its PubChem SMILES string, and every value in this section is computed from that structure.
2D skeletal formula · N2H4
Hybridisation
N sp³ ×2
Electron count
14 valence e⁻ · 2 lone pairs
Identifiers from PubChem (NIH, public domain). Structure diagram drawn with RDKit from the SMILES string. Geometry and hybridisation are computed from the connection table, not measured.
§ 04 · First-aid measures
Hydrazine first aid measures
Call your national emergency number first. These are published first-aid measures, not medical advice, and they do not replace emergency services, a poison control centre or the supplier's safety data sheet.
§4–§6 below reproduce the CAMEO Chemicals entry HYDRAZINE, ANHYDROUS. CAMEO publishes response data per product entry, so the entry can describe a solution, a refrigerated liquid or a molten form rather than the pure substance in §9 — check it matches what you are handling.
Warning: Effects may be delayed for hours to days. Caution is advised.
Signs and Symptoms of Acute Hydrazine Exposure: Signs and symptoms of acute exposure to hydrazine may include severe eye irritation, facial numbness, facial swelling, and increased salivation. Hydrazine vapor may immediately irritate the nose and throat. Headache, twitching, seizures, convulsions, and coma may also occur. Gastrointestinal signs and symptoms include anorexia, nausea, and vomiting. Pulmonary edema and hypotension (low blood pressure) are common. Hydrazine is toxic to the liver, ruptures red blood cells, and may cause kidney damage. Dermal contact may result in irritation or severe burns.
Emergency Life-Support Procedures: Acute exposure to hydrazine may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.
Inhalation Exposure: 1. Move victims to fresh air. Emergency personnel should avoid self-exposure to hydrazine. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 4. Transport to a health care facility.
Dermal/Eye Exposure: 1. Remove victims from exposure. Emergency personnel should avoid self- exposure to hydrazine. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 3. Remove contaminated clothing as soon as possible. 4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes. 5. Wash exposed skin areas THOROUGHLY with soap and water. 6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 7. Transport to a health care facility.
Ingestion Exposure: 1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults 250 mL (8 oz or 1 cup). Water or milk should be given only if victims are conscious and alert. 4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water. 5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults. 6. Transport to a health care facility.
Source: EPA, 1998 — via CAMEO Chemicals (NOAA), public domain.
§ 05 · Fire-fighting measures
Hydrazine fire fighting measures
ERG 2024 · GUIDE 132 Flammable Liquids - CorrosiveERG guidance is written per response guide, not per substance — Guide 132 covers every material assigned to it, so a few sentences reference other UN numbers in the same group.
Fire and explosion hazard
It is a flammable/combustible material and may be ignited by heat, sparks, or flames. Vapor may travel to a source of ignition and flash back. Container may explode in heat of fire. Vapor explosion and poison hazard indoors, outdoors, or in sewers. Runoff to sewer may create fire or explosion hazard. Vapors form explosive mixtures with air. May continue to burn in the absence of air. Decomposition gives off toxic nitrogen compound fumes. Can catch fire when in contact with porous materials such as wood, asbestos, cloth, earth, and rusty metals. Incompatible with oxidizers, hydrogen peroxide, nitric acid, metal oxides, and strong acids. Hazardous polymerization may not occur.
Extinguishing media and tactics
Stay upwind; keep out of low areas. Wear positive pressure breathing apparatus and protective clothing. Isolate for one-half mile in all directions if tank car or truck is involved in fire. Move container from fire area if you can do so without risk. Dike fire control water for later disposal; do not scatter material. Spray cooling water on containers that are exposed to flames until well after fire is out.
Small fires: dry chemical, carbon dioxide, water spray or foam. Large fires: water spray, fog, or foam.
Source: EPA, 1998 — via CAMEO Chemicals (NOAA), public domain. Entry: HYDRAZINE, ANHYDROUS.
§ 06 · Accidental release measures
Hydrazine spill and leak response
Containment and clean-up
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb with earth, sand or other non-combustible material. For hydrazine, absorb with DRY sand or inert absorbent (vermiculite or absorbent pads). Use clean, non-sparking tools to collect absorbed material.
LARGE SPILLDike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces.
Initial isolation and evacuation
IMMEDIATE PRECAUTIONARY MEASUREIsolate spill or leak area for at least 50 meters (150 feet) in all directions.
SPILLIncrease the immediate precautionary measure distance, in the downwind direction, as necessary.
FIREIf tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.
Source: ERG, 2024 — via CAMEO Chemicals (NOAA), public domain. Entry: HYDRAZINE, ANHYDROUS.
§ 07 · Handling and storage
Hydrazine computed storage compatibility
Derived from CLP Annex VI classification and CAMEO reactive-group data — not copied from a PDF.
⚠ Air-Reactive⚠ Highly Flammable⚠ Strong Reducing Agent
⛔ Never store with
↔ Keep separate
Full interactive verdict — reactions, gas release on contact, ADR forms →
§ 08 · Exposure controls
Hydrazine exposure limits (IDLH)
IDLH
Immediately Dangerous to Life or Health
50 ppm
Carcinogen
NIOSH lists hydrazine as a potential occupational carcinogen — exposure should be kept as low as achievable regardless of the IDLH figure.
NIOSH Pocket Guide — Hydrazine →
IDLH from the NIOSH Pocket Guide to Chemical Hazards (CDC, U.S. public domain), via CAMEO Chemicals. Occupational exposure limits — OSHA PEL, NIOSH REL and EU IOELV — are not published on this page yet.
§ 09 · Physical and chemical properties
Hydrazine physical properties
Fire-relevant values first — flash point and explosion limits decide the storage and ventilation regime.
Flash point
52 °C
Explosion limits
4.7 – 100 %
LEL / UEL in air, vol.
Autoignition
270 °C
Source: CAMEO Chemicals (NOAA, public domain); per-value source references stored in the database.
§ 10 · Stability and reactivity
Reactive group (CAMEO/NOAA): Azo, Diazo, Azido, Hydrazine, and Azide Compounds, Bases, Strong. Our database documents 73 incompatible and 30 caution reaction-partner groups for hydrazine — including which combinations release gas on contact. See the per-partner breakdown with gas release →
73
Incompatible
30
Caution
§ 13 · Disposal considerations
Dispose of waste and residues in accordance with local and national regulations — in the EU under the Waste Framework Directive 2008/98/EC. Never discharge to drains or municipal waste; hand contaminated packaging and unused product to an authorised waste-disposal company. The supplier's SDS section 13 lists the applicable waste codes for the specific product.
§ 14 · Transport information
Hydrazine road transport — ADR 2025
UN number
Proper shipping name
HYDRAZINE, ANHYDROUS
Class · PG
8 · I
Classification code
CFT
Transport category
1
ADR labels
8, 3, 6.1
UN number
Proper shipping name
HYDRAZINE, AQUEOUS SOLUTION with not more than 37 % hydrazine, by mass
Class · PG
6.1 · III
Classification code
T4
Transport category
2
ADR labels
6.1
Hazard ID (Kemler) / UN plate
Top: hazard identification number (Kemler). Bottom: UN number — as carried on the orange plate of the transport unit.
Source: UN ADR 2025 (ECE/TRANS/352), Table A. Road (ADR) only — for sea (IMDG) and air (IATA), consult the supplier's SDS §14.
MSDS vs SDS
Hydrazine MSDS vs SDS: is there a difference?
MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the format is set by REACH Annex II. So a "hydrazine MSDS" and a "hydrazine SDS" refer to the same document — today it is issued as an SDS. Full breakdown of the differences →
Other bases in our database
Substance profile
What hydrazine is
Physical and chemical properties with the conditions each value was measured under, synonyms, formula and the harmonised CLP classification →
Compliance hub
From classification to SDS
The classification above corresponds to Section 2 of a Safety Data Sheet. Learn how a compliant 16-section SDS is structured and authored →
GHS label maker
Build the label for hydrazine
Pictograms, signal word and H-statements combined into a compliant label layout →
§ 16 · Sources
- Classification: Regulation (EC) No 1272/2008 (CLP), Annex VI
- Transport: UN ADR 2025 (UNECE), Table A
- Reactivity: NOAA CAMEO Chemicals reactive-group matrix (public domain)
- Physical properties: CAMEO Chemicals (NOAA, public domain) — per-value source references stored in the database
- Emergency response (§4–§6): ERG 2024 (PHMSA) · NIOSH Pocket Guide (CDC) · CHRIS (USCG) · NTP · EPA — via CAMEO Chemicals (NOAA), all US federal public domain, reproduced verbatim
- Substance data: PubChem · ECHA
Reference aid only. This page summarises the harmonised EU classification and computed storage guidance — it is not a Safety Data Sheet and does not replace one. Always verify hazards, handling and storage against the supplier's SDS (sections 7 and 10) and local regulations before use. Page updated 2026-08-11.
Frequently asked questions about hydrazine
Is an MSDS the same as an SDS?
In practice, yes. MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the SDS format is set by REACH Annex II. A document you find labelled "hydrazine MSDS" is today issued as an SDS.
What GHS pictograms does hydrazine require?
Under the harmonised EU classification (CLP Annex VI), hydrazine carries GHS02 and GHS05 and GHS06 and GHS08 and GHS09 with the signal word "Danger". Hazard statements: H226, H350, H331, H311, H301, H314, H317, H400, H410. A supplier's SDS may add self-classified hazards on top of this harmonised minimum.
What should hydrazine never be stored with?
Based on its storage classes (Bases, Flammable liquids, Acute toxics), hydrazine must not share storage with: Mineral acids; Organic acids; Organic peroxides & self-reactives; Oxidizing acids; Oxidizers; Water-reactives. Verify against the supplier's SDS sections 7 and 10 before finalising storage.
Where can I download an official hydrazine SDS PDF?
From your own supplier — an SDS is issued per product and supplier, so the correct PDF for an inspection is the one matching the product you actually purchased. The supplier links on this page lead to the official SDS libraries of major distributors.
Call emergency services first
112 in the EU · 911 in the US. This screen is published response information, not medical advice, and it does not replace emergency services, a poison centre or the supplier's safety data sheet.
Text below is the CAMEO Chemicals entry HYDRAZINE, ANHYDROUS — confirm it matches the form in front of you.
01 · First aid
What to do for the person
Warning: Effects may be delayed for hours to days. Caution is advised.
Signs and Symptoms of Acute Hydrazine Exposure: Signs and symptoms of acute exposure to hydrazine may include severe eye irritation, facial numbness, facial swelling, and increased salivation. Hydrazine vapor may immediately irritate the nose and throat. Headache, twitching, seizures, convulsions, and coma may also occur. Gastrointestinal signs and symptoms include anorexia, nausea, and vomiting. Pulmonary edema and hypotension (low blood pressure) are common. Hydrazine is toxic to the liver, ruptures red blood cells, and may cause kidney damage. Dermal contact may result in irritation or severe burns.
Emergency Life-Support Procedures: Acute exposure to hydrazine may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.
Inhalation Exposure: 1. Move victims to fresh air. Emergency personnel should avoid self-exposure to hydrazine. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 4. Transport to a health care facility.
Dermal/Eye Exposure: 1. Remove victims from exposure. Emergency personnel should avoid self- exposure to hydrazine. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 3. Remove contaminated clothing as soon as possible. 4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes. 5. Wash exposed skin areas THOROUGHLY with soap and water. 6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 7. Transport to a health care facility.
Ingestion Exposure: 1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults 250 mL (8 oz or 1 cup). Water or milk should be given only if victims are conscious and alert. 4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water. 5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults. 6. Transport to a health care facility.
02 · Fire
Extinguishing and tactics
Fire and explosion hazard
It is a flammable/combustible material and may be ignited by heat, sparks, or flames. Vapor may travel to a source of ignition and flash back. Container may explode in heat of fire. Vapor explosion and poison hazard indoors, outdoors, or in sewers. Runoff to sewer may create fire or explosion hazard. Vapors form explosive mixtures with air. May continue to burn in the absence of air. Decomposition gives off toxic nitrogen compound fumes. Can catch fire when in contact with porous materials such as wood, asbestos, cloth, earth, and rusty metals. Incompatible with oxidizers, hydrogen peroxide, nitric acid, metal oxides, and strong acids. Hazardous polymerization may not occur.
Extinguishing media and tactics
Stay upwind; keep out of low areas. Wear positive pressure breathing apparatus and protective clothing. Isolate for one-half mile in all directions if tank car or truck is involved in fire. Move container from fire area if you can do so without risk. Dike fire control water for later disposal; do not scatter material. Spray cooling water on containers that are exposed to flames until well after fire is out.
Small fires: dry chemical, carbon dioxide, water spray or foam. Large fires: water spray, fog, or foam.
03 · Spill
Containment, isolation, evacuation
Containment and clean-up
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb with earth, sand or other non-combustible material. For hydrazine, absorb with DRY sand or inert absorbent (vermiculite or absorbent pads). Use clean, non-sparking tools to collect absorbed material.
LARGE SPILLDike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces.
Initial isolation and evacuation
IMMEDIATE PRECAUTIONARY MEASUREIsolate spill or leak area for at least 50 meters (150 feet) in all directions.
SPILLIncrease the immediate precautionary measure distance, in the downwind direction, as necessary.
FIREIf tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.
Sources: ERG 2024 (PHMSA) · NIOSH Pocket Guide (CDC) · CHRIS (USCG) · NTP · EPA — via CAMEO Chemicals (NOAA), public domain. Text reproduced verbatim.