Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

1,1-Dimethylhydrazine

1,1-Dimethylhydrazine is a clear, colorless liquid with characteristic ammonia like fishy odor of aliphatic hydrazines.

CAS 57-14-7 C2H8N2 60.1 g/mol Danger

01 · Identification

What 1,1-Dimethylhydrazine is

1,1-Dimethylhydrazine is a clear, colorless liquid with characteristic ammonia like fishy odor of aliphatic hydrazines. Its molecular formula is C2H8N2 and its molecular weight is 60.1 g/mol. It boils at 63.9 °C, melts at -58 °C.

Under the GHS it carries the signal word Danger. It is classed as hazardous Air Pollutants (HAPs).

02 · Identifiers

1,1-Dimethylhydrazine identifiers and molecular data

1,1-Dimethylhydrazine CAS number and EC number

CAS number57-14-7
EC number200-316-0
Index number (CLP Annex VI)007-012-00-5

1,1-Dimethylhydrazine molecular formula and molecular weight

Molecular formulaC2H8N2
Molecular weight60.1 g/mol
Chemical class Hazardous Air Pollutants (HAPs)

Other names for 1,1-Dimethylhydrazine

  • N,N-dimethylhydrazine

03 · GHS classification

1,1-Dimethylhydrazine hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

1,1-Dimethylhydrazine pictograms and signal word

Signal wordDanger

1,1-Dimethylhydrazine hazard class and category

GHS hazard classes 1,1-Dimethylhydrazine falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 2 H225 GHS02
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - inhalation GHS chapter 3.1 Category 3 H331 GHS06
Skin corrosion/irritation GHS chapter 3.2 Category 1A or 1B or 1C H314 GHS05
Carcinogenicity GHS chapter 3.6 Category 1A or 1B H350 GHS08
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 2 H411 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

1,1-Dimethylhydrazine hazard statements (H-codes)

Hazard statements assigned to 1,1-Dimethylhydrazine
CodeHazard statement
H225 Highly flammable liquid and vapour.
H350 May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H331 Toxic if inhaled.
H301 Toxic if swallowed.
H314 Causes severe skin burns and eye damage.
H411 Toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to 1,1-Dimethylhydrazine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 1,1-Dimethylhydrazine

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1,1-Dimethylhydrazine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

1,1-Dimethylhydrazine precautionary statements

CLP Annex VI assigns 20 precautionary statements to 1,1-Dimethylhydrazine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

1,1-Dimethylhydrazine name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български N , N -диметилхидразин
Spanish español N , N -Dimetilhidrazina
Czech čeština N, N -dimethylhydrazin
Danish dansk N, N- dimethylhydrazin
German Deutsch N , N -Dimethylhydrazin
Estonian eesti N , N -dimetüülhüdrasiin
Greek ελληνικά N , N -διμεθυλυδραζίνη
English English N , N -dimethylhydrazine
French français N , N -diméthylhydrazine
Croatian hrvatski N , N -dimetil-hidrazin
Italian italiano N , N -dimetilidrazina
Latvian latviešu N , N -dimetilhidrazīns
Lithuanian lietuvių N , N -dimetilhidrazinas
Hungarian magyar N , N -dimetilhidrazin
Maltese Malti N , N -dimetilidrażina
Dutch Nederlands N , N -dimethylhydrazine
Polish polski N, N-dimetylohydrazyna
Portuguese português N , N -dimetil-hidrazina
Romanian română N , N -dimetilhidrazină
Slovak slovenčina N, N -dimetylhydrazín
Slovenian slovenščina N , N -dimetilhidrazin
Finnish suomi N , N -dimetyylihydratsiini
Swedish svenska N , N -dimetylhydrazin

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

1,1-Dimethylhydrazine GHS label elements

Everything CLP Annex VI fixes for 1,1-Dimethylhydrazine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS06 Skull and crossbones pictogramGHS08 Health hazard pictogramGHS05 Corrosion pictogramGHS09 Environment pictogram

Danger

1,1-Dimethylhydrazine

  • Highly flammable liquid and vapour.
  • May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Toxic if inhaled.
  • Toxic if swallowed.
  • Causes severe skin burns and eye damage.
  • Toxic to aquatic life with long lasting effects.
  • Obtain special instructions before use.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF INHALED:
  • IF exposed or concerned:
  • Immediately call a POISON CENTER/doctor/
  • Get medical advice/attention.
  • Rinse mouth.
  • Do NOT induce vomiting.
  • Collect spillage.
  • Store in a well-ventilated place.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 1,1-Dimethylhydrazine in the GHS label constructor →

07 · Health hazards

1,1-Dimethylhydrazine health hazards and exposure limits

1,1-Dimethylhydrazine hazard summary

1,1-Dimethylhydrazine is primarily used as a high-energy fuel in military applications and as a rocket propellant and fuel for thrusters. Acute (short-term) inhalation exposure of humans to 1,1- dimethylhydrazine results in nose and throat irritation, mild conjunctivitis, nausea, and vomiting. It is also highly corrosive and irritating to the skin, eyes, and mucous membranes. Liver damage in humans may occur from chronic (long-term) exposure to 1,1-dimethylhydrazine. No information is available on the reproductive, developmental, or carcinogenic effects of 1,1-dimethylhydrazine in humans. Carcinogenic effects have been observed in animals exposed to 1,1-dimethylhydrazine by inhalation and orally, predominantly to the lung and liver. EPA has not classified 1,1-dimethylhydrazine for potential carcinogenicity. The International Agency for Research on Cancer (IARC) has classified 1,1- dimethylhydrazine as a Group 2B, the chemical is possibly carcinogenic to humans.

Source: EPA Hazardous Air Pollutants

1,1-Dimethylhydrazine carcinogenicity classification

IARC classification Group 2B — Possibly carcinogenic to humans
IARC monographs Volume 4: (1974) Some Aromatic Amines, Hydrazine and Related Substances, N-Nitroso Compounds and Miscellaneous Alkylating Agents; Volume 71: (1999) Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide (Part 1, Part 2, Part 3)

Cancer Classification: Group B2 Probable Human Carcinogen

Source: Hazardous Substances Data Bank (HSDB)

Evaluation: No epidemiological data on the carcinogenicity of 1,1-dimethylhydrazine were available. There is sufficient evidence in experimental animals for the carcinogenicity of 1,1-dimethylhydrazine. Overall evaluation: 1,1-Dimethylhydrazine is possibly carcinogenic to humans (Group 2B).

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

1,1-Dimethylhydrazine occupational exposure limits

US occupational exposure limits reported for 1,1-Dimethylhydrazine. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 0.5 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
PEL 0.5 ppm (1 mg/m³) Occupational Safety and Health Administration (OSHA)
PEL TWA 0.5 ppm (1 mg/m3) [skin] The National Institute for Occupational Safety and Health (NIOSH)
REL 0.06 ppm (0.15 mg/m³) [120 minutes] Occupational Safety and Health Administration (OSHA)
REL Ca C 0.06 ppm (0.15 mg/m3) [2-hr] See Appendix A The National Institute for Occupational Safety and Health (NIOSH)
IDLH 15 ppm ; A potential occupational carcinogen. (NIOSH, 2024) CAMEO Chemicals
IDLH 15.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
IDLH 15 ppm; NIOSH considers 1,1-dimethylhydrazine to be a potential occupational carcinogen. Hazardous Substances Data Bank (HSDB)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

1,1-Dimethylhydrazine properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

1,1-Dimethylhydrazine boiling point

Property Value Conditions Source
Boiling point 63.9 °C (147 °F) at 760 mmHg HSDB
63.89 °C (147 °F) NIOSH
63.89 °C (147 °F) at 760 mmHg CAMEO

1,1-Dimethylhydrazine melting point

Property Value Conditions Source
Melting point -58 °C (-72.4 °F) HSDB
-57.78 °C (-72 °F) NIOSH

1,1-Dimethylhydrazine density

Property Value Conditions Source
Density 0.79 g/cm³ NIOSH
0.7914 g/cm³ at 22 °C CAMEO
0.782 g/cm³ at 25 °C HSDB

1,1-Dimethylhydrazine solubility

Property Value Conditions Source
Solubility Very sol in methanol and ethanol HSDB
>10% in water HSDB
Decomposes (NTP, 1992) decomposes CAMEO

1,1-Dimethylhydrazine vapor pressure

Property Value Conditions Source
Vapor pressure 103 mmHg NIOSH
167 mmHg at 25 °C HSDB
157 mmHg at 25 °C CAMEO

1,1-Dimethylhydrazine flash point

Property Value Conditions Source
Flash point -15 °C (5 °F) closed cup HSDB
-15 °C (5 °F) NIOSH

1,1-Dimethylhydrazine autoignition temperature

Property Value Conditions Source
Autoignition temperature 249 °C (480.2 °F) HSDB
248.89 °C (480 °F) CAMEO

1,1-Dimethylhydrazine lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 2 % by volume HSDB

1,1-Dimethylhydrazine upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 95 % by volume HSDB

1,1-Dimethylhydrazine vapor density

Property Value Conditions Source
Vapor density 1.94 (air = 1) HSDB
2.1 (air = 1) ICSC

1,1-Dimethylhydrazine odor threshold

Property Value Conditions Source
Odor threshold 12.0 mg/cu m (low); 20.0 mg/cu m (high) HSDB
Sharp, ammonia-like odor. Odor threshold: 0.3, 11.7, and 6-14 ppm. HSDB

1,1-Dimethylhydrazine critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 250 °C (482 °F) HSDB

1,1-Dimethylhydrazine corrosivity

Property Value Conditions Source
Corrosivity Highly corrosive. HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

1,1-Dimethylhydrazine fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

1,1-Dimethylhydrazine fire potential

It is flammable over a wide range of vapor air concentrations.

Source: Hazardous Substances Data Bank (HSDB)

Odor

The warning properties (irritation & odor) of the hydrazines are probably sufficient to prevent acute poisoning from short exposures. However, in view of the chronic toxicity properties, the warning properties should not be considered adequate for prolonged exposures. /Hydrazines/

Source: HSDB

10 · Handling and storage

1,1-Dimethylhydrazine storage and handling

1,1-Dimethylhydrazine safe storage

Fireproof. Provision to contain effluent from fire extinguishing. Separated from strong oxidants and strong acids. Dry. Well closed. Keep in a well-ventilated room. Do NOT store or transport in containers made from plastic. Store in an area without drain or sewer access.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

1,1-Dimethylhydrazine storage conditions

PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practicable to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/

Source: Hazardous Substances Data Bank (HSDB)

1,1-Dimethylhydrazine incompatible materials

Contact of dicyanofurazan, or its N-oxide (dicyanofuroxan), with ... dimethylhydrazine ... is instantaneously explosive.

Source: Hazardous Substances Data Bank (HSDB)

1,1-Dimethylhydrazine reactivity

1,1-DIMETHYLHYDRAZINE is a powerful reducing agent. Ignition can occur on contact with oxidizing agents such hydrogen peroxide and fuming nitric acid [Haz. Chem. Data(1966)]. Also reacts as a base to neutralize acids in exothermic reactions.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 1,1-Dimethylhydrazine in the storage compatibility matrix →

11 · Questions

1,1-Dimethylhydrazine — frequently asked questions

What is the CAS number of 1,1-Dimethylhydrazine?

The CAS number of 1,1-Dimethylhydrazine is 57-14-7. Its EC number is 200-316-0.

What is the chemical formula of 1,1-Dimethylhydrazine?

The molecular formula of 1,1-Dimethylhydrazine is C2H8N2 and its molecular weight is 60.1 g/mol.

What does a 1,1-Dimethylhydrazine label have to show?

Under CLP Annex VI the label for 1,1-Dimethylhydrazine carries the pictograms Flame, Skull and crossbones, Health hazard, Corrosion and Environment and the signal word is Danger.

Is 1,1-Dimethylhydrazine flammable?

Yes. CLP Annex VI assigns 1,1-Dimethylhydrazine H225 — highly flammable liquid and vapour. The flash point reported for it is -15 °C (5 °F), closed cup (HSDB).

Is 1,1-Dimethylhydrazine a carcinogen?

Yes. CLP Annex VI classifies 1,1-Dimethylhydrazine as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 2B: possibly carcinogenic to humans.

What is the exposure limit for 1,1-Dimethylhydrazine?

The US occupational exposure limit reported for 1,1-Dimethylhydrazine is 0.5 [ppm] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of 1,1-Dimethylhydrazine?

The boiling point reported for 1,1-Dimethylhydrazine is 63.9 °C (147 °F), at 760 mmHg (HSDB).

What is the melting point of 1,1-Dimethylhydrazine?

The melting point reported for 1,1-Dimethylhydrazine is -58 °C (-72.4 °F) (HSDB).

How should 1,1-Dimethylhydrazine be stored?

CLP Annex VI assigns 1,1-Dimethylhydrazine the storage statement P403. PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practicable to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/ (Hazardous Substances Data Bank (HSDB))

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