Substance profile
1,2-bis(2-methoxyethoxy)ethane
1,2-bis(2-methoxyethoxy)ethane: triethylene glycol dimethyl ether is a clear colorless liquid with a mild ethereal odor.
01 · Identification
What 1,2-bis(2-methoxyethoxy)ethane is
1,2-bis(2-methoxyethoxy)ethane: triethylene glycol dimethyl ether is a clear colorless liquid with a mild ethereal odor. Its molecular formula is C8H18O4 and its molecular weight is 178.23 g/mol. It boils at 216 °C, melts at -45 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
1,2-bis(2-methoxyethoxy)ethane identifiers and molecular data
1,2-bis(2-methoxyethoxy)ethane CAS number and EC number
1,2-bis(2-methoxyethoxy)ethane molecular formula and molecular weight
Other names for 1,2-bis(2-methoxyethoxy)ethane
- TEGDME
- triethylene glycol dimethyl ether
- triglyme
03 · GHS classification
1,2-bis(2-methoxyethoxy)ethane hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
1,2-bis(2-methoxyethoxy)ethane pictograms and signal word
1,2-bis(2-methoxyethoxy)ethane hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H360Df | May damage the unborn child. Suspected of damaging fertility. |
1,2-bis(2-methoxyethoxy)ethane supplemental EU statements (EUH)
| Code | Statement |
|---|---|
| EUH019 | May form explosive peroxides. |
This page lists only the codes assigned to 1,2-bis(2-methoxyethoxy)et…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 1,2-bis(2-methoxyethoxy)et…
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1,2-bis(2-methoxyethox… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
1,2-bis(2-methoxyethoxy)ethane precautionary statements
CLP Annex VI assigns 4 precautionary statements to 1,2-bis(2-methoxyethoxy)et…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
1,2-bis(2-methoxyethoxy)ethane name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 1,2-бис(2-метоксиетокси)етан TEGDMEдиметилов етер на триетиленгликолатриглим |
| Spanish español | 1,2-Bis(2-metoxietoxi)etano TEGDMEéter dimetílico de trietilenglicoltriglimo |
| Czech čeština | 1,2-bis(2-methoxyethoxy)ethan TEGDMEtriethylenglykoldimethylethertriglym |
| Danish dansk | 1,2-bis(2-methoxyethoxy)ethan TEGDMEtriethylenglycoldimethylethertriglym |
| German Deutsch | 1,2-Bis(2-methoxyethoxy)ethan TEGDMETriethylenglycoldimethyletherTriglyme |
| Estonian eesti | 1,2-bis(2-metoksüetoksü)etaan TEGDMEtrietüleenglükooli dimetüüleetertriglüüm |
| Greek ελληνικά | 1,2-δις(2-μεθοξυαιθοξυ)αιθάνιο TEGDMEτριαιθυλενογλυκολοδιμεθυλαιθέραςτριγλύμη |
| English English | 1,2-bis(2-methoxyethoxy)ethane TEGDMEtriethylene glycol dimethyl ethertriglyme |
| French français | 1,2-bis(2-méthoxyéthoxy)éthane TEGDMEéther diméthylique du triéthylène glycoltriglyme |
| Croatian hrvatski | 1,2-bis(2-metoksietoksi)etan TEGDMEtrietilen-glikol-dimetil-etertriglim |
| Italian italiano | 1,2-bis(2-metossietossi)etano TEGDMEtrietilenglicol dimetileteretriglyme |
| Latvian latviešu | 1,2-bis(2-metoksietoksi)etāns TEGDMEtrietilēnglikola dimetilēteristriglīms |
| Lithuanian lietuvių | 1,2-bis(2-metoksietoksi)etanas TEGDMEtrietilenglikolio dimetileteristriglimas |
| Hungarian magyar | 1,2-bisz(2-metoxietoxi)etán TEGDMEtrietilén-glikol-dimetil-étertriglim |
| Maltese Malti | 1,2-bis(2-metossietossi)etan TEGDME eter tad-dimetil tal-glikol tat-trietilentriglim |
| Dutch Nederlands | 1,2-bis(2-methoxyethoxy)ethaan TEGDMEtriëthyleenglycoldimethylethertriglyme |
| Polish polski | 1,2-bis(2-metoksyetoksy)etan TEGDMEeter dimetylowy glikolu trietylenowego |
| Portuguese português | 1,2-bis(2-metoxietoxi)etano TEGDMEéter dimetílico de trietilenoglicoltriglima |
| Romanian română | 1,2-bis(2-metoxietoxi)etan TEGDMEeter dimetilic al trietilen-glicoluluitriglim |
| Slovak slovenčina | 1,2-bis(2-metoxyetoxy)etán TEGDMEtrietylénglykol-dimetylétertriglym |
| Slovenian slovenščina | 1,2-bis(2-metoksietoksi)etan TEGDMEtrietilen glikol dimetil etertriglim |
| Finnish suomi | 1,2-bis(2-metoksietoksi)etaani tegdmetrietyleeniglykolin dimetyylieetteritriglyymi |
| Swedish svenska | 1,2-bis(2-metoxietoxi)etan TEGDMEtrietylenglykoldimetyletertriglym |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
1,2-bis(2-methoxyethoxy)ethane GHS label elements
Everything CLP Annex VI fixes for 1,2-bis(2-methoxyethoxy)et…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
1,2-bis(2-methoxyethoxy)ethane
- May damage the unborn child. Suspected of damaging fertility.
- May form explosive peroxides.
- Obtain special instructions before use.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF exposed or concerned:
- Get medical advice/attention.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 1,2-bis(2-methoxyethoxy)et… in the GHS label constructor →
07 · Health hazards
1,2-bis(2-methoxyethoxy)ethane health hazards and exposure limits
1,2-bis(2-methoxyethoxy)ethane hazard summary
May have adverse effects on human reproduction, based on animal studies; [ICSC] Labeled as May impair fertility and May cause harm to the unborn child by EU regulations; [Glycol Ethers Online] Prolonged contact with air can form explosive peroxides; [CAMEO] A skin and eye irritant; [NTP] May form explosive peroxides; An irritant; May cause impaired fertility and fetal toxicity; [Alfa Aesar MSDS] See Monoglyme.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
1,2-bis(2-methoxyethoxy)ethane properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
1,2-bis(2-methoxyethoxy)ethane boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 216.11 °C (421 °F) | at 760 mmHg | CAMEO |
| 216 °C (420.8 °F) | ICSC | ||
| 216 °C (420.8 °F) | at 760 mmHg | DOE PAC |
1,2-bis(2-methoxyethoxy)ethane melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -45 °C (-49 °F) | CAMEO |
1,2-bis(2-methoxyethoxy)ethane density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 0.99 g/cm³ | ICSC | |
| 0.99 g/cm³ | at 20 °C | CAMEO | |
| 0.986 g/cm³ | at 25 °C | DOE PAC |
1,2-bis(2-methoxyethoxy)ethane solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Solubility in water: miscible | ICSC | |
| greater than or equal to 100 mg/mL at 70 °F (NTP, 1992) | at 21.11 °C | CAMEO |
1,2-bis(2-methoxyethoxy)ethane vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.9 mmHg | at 20 °C | CAMEO |
| 0.9001 mmHg | at 20 °C | ICSC | |
| 0.04 mmHg | Haz-Map |
1,2-bis(2-methoxyethoxy)ethane flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 111.11 °C (232 °F) | CAMEO | |
| 111 °C (231.8 °F) | ICSC |
1,2-bis(2-methoxyethoxy)ethane autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 630 °C (1166 °F) | CAMEO |
1,2-bis(2-methoxyethoxy)ethane vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 4.7 (air = 1) | CAMEO | |
| 6.14 (air = 1) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
1,2-bis(2-methoxyethoxy)ethane storage and handling
1,2-bis(2-methoxyethoxy)ethane safe storage
Separated from strong oxidants.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
1,2-bis(2-methoxyethoxy)ethane reactivity
TRIETHYLENE GLYCOL DIMETHYL ETHER forms explosive peroxides on prolonged exposure to air. Its decomposition products may be sensitive to shock. The bulk chemical is stable for 2 weeks at temperatures up to 140 °F when protected from light. This chemical is incompatible with strong oxidizers. It is also incompatible with strong acids. It may react with peroxides, oxygen, nitric acid and sulfuric acid. (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 1,2-bis(2-methoxyethoxy)e… in the storage compatibility matrix →
10 · Questions
1,2-bis(2-methoxyethoxy)ethane — frequently asked questions
What is the CAS number of 1,2-bis(2-methoxyethoxy)ethane?
The CAS number of 1,2-bis(2-methoxyethoxy)ethane is 112-49-2. Its EC number is 203-977-3.
What is the chemical formula of 1,2-bis(2-methoxyethoxy)ethane?
The molecular formula of 1,2-bis(2-methoxyethoxy)ethane is C8H18O4 and its molecular weight is 178.23 g/mol.
What does a 1,2-bis(2-methoxyethoxy)ethane label have to show?
Under CLP Annex VI the label for 1,2-bis(2-methoxyethoxy)ethane carries the pictogram Health hazard and the signal word is Danger.
Is 1,2-bis(2-methoxyethoxy)ethane flammable?
CLP Annex VI assigns 1,2-bis(2-methoxyethoxy)ethane no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 111.11 °C (232 °F) (CAMEO).
Is 1,2-bis(2-methoxyethoxy)ethane a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 1,2-bis(2-methoxyethoxy)ethane. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of 1,2-bis(2-methoxyethoxy)ethane?
The boiling point reported for 1,2-bis(2-methoxyethoxy)ethane is 216.11 °C (421 °F), at 760 mmHg (CAMEO).
What is the melting point of 1,2-bis(2-methoxyethoxy)ethane?
The melting point reported for 1,2-bis(2-methoxyethoxy)ethane is -45 °C (-49 °F) (CAMEO).
Nearby
Substances next to 1,2-bis(2-methoxyethoxy)et…
Keep going: substances starting with 0–9, or search the whole database by name, CAS number, pictogram or signal word.