Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyran

1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyran is colorless crystals from ethanol with a strong musk odor.

CAS 1222-05-5 Warning

01 · Identification

What 1,3,4,6,7,8-hexahydro-4,6,6,7… is

1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyran is colorless crystals from ethanol with a strong musk odor. It melts at 57.5 °C.

Under the GHS it carries the signal word Warning.

02 · Identifiers

1,3,4,6,7,8-hexahydro-4,6,6,7… identifiers and molecular data

1,3,4,6,7,8-hexahydro-4,6,6,7… CAS number and EC number

CAS number1222-05-5
EC number214-946-9
Index number (CLP Annex VI)603-212-00-7

Other names for 1,3,4,6,7,8-hexahydro-4,6,6,7…

  • galaxolide
  • (HHCB)

03 · GHS classification

1,3,4,6,7,8-hexahydro-4,6,6,7… hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

1,3,4,6,7,8-hexahydro-4,6,6,7… pictograms and signal word

Signal wordWarning

1,3,4,6,7,8-hexahydro-4,6,6,7… hazard class and category

GHS hazard classes 1,3,4,6,7,8-hexahydro-4,6… falls into
Hazard class Category From code Pictogram
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

1,3,4,6,7,8-hexahydro-4,6,6,7… hazard statements (H-codes)

Hazard statements assigned to 1,3,4,6,7,8-hexahydro-4,6…
CodeHazard statement
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to 1,3,4,6,7,8-hexahydro-4,6…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 1,3,4,6,7,8-hexahydro-4,6…

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1,3,4,6,7,8-hexahydro… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

1,3,4,6,7,8-hexahydro-4,6,6,7… precautionary statements

CLP Annex VI assigns 3 precautionary statements to 1,3,4,6,7,8-hexahydro-4,6…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Prevention

What to do before and during handling so the hazard never happens.

Response

What to do once exposure, spillage or fire has already happened.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

1,3,4,6,7,8-hexahydro-4,6,6,7… name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български 4,6,6,7,8,8-хексаметил-1,3,4,6,7,8-хексахидроиндено[5,6- c ]пиран галаксолид(HHCB)
Spanish español 1,3,4,6,7,8-Hexahidro-4,6,6,7,8,8-hexametilindeno[5,6- c ]pirano galaxólido(HHCB)
Czech čeština 4,6,6,7,8,8-hexamethyl- 1,3,4,6,7,8-hexahydroindeno[5,6- c ]pyran galaxolid(HHCB)
Danish dansk 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6- c ]pyran galaxolid(HHCB)
German Deutsch 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6- c ]pyran Galaxolid(HHCB)
Estonian eesti 1,3,4,6,7,8-heksahüdro-4,6,6,7,8,8-heksametüülindeno[5,6- c ]püraan galaksoliid(HHCB)
Greek ελληνικά 1,3,4,6,7,8-εξαϋδρο-4,6,6,7,8,8-εξαμεθυλινδενο[5,6- c ]πυράνιο γαλαξολίδιο(HHCB)
English English 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6- c ]pyran galaxolide(HHCB)
French français 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexaméthylindéno[5,6- c ]pyrane galaxolide(HHCB)
Croatian hrvatski 1,3,4,6,7,8-heksahidro-4,6,6,7,8,8-heksametilindeno[5,6- c ]piran galaksolid(HHCB)
Italian italiano 1,3,4,6,7,8-esaidro-4,6,6,7,8,8-esametillinden[5,6-c]pirano galaxolide(HHCB)
Latvian latviešu 1,3,4,6,7,8-heksahidro-4,6,6,7,8,8-heksametilindeno[5,6- c ]pirāns galaksolīds(HHCB)
Lithuanian lietuvių 1,3,4,6,7,8-heksahidro-4,6,6,7,8,8-heksametilindeno[5,6- c ]piranas galaksolidas(HHCB)
Hungarian magyar 1,3,4,6,7,8-hexahidro-4,6,6,7,8,8-hexametilindeno[5,6-c]pirán galaxolid(HHCB)
Maltese Malti 1,3,4,6,7,8-eżaidro-4,6,6,7,8,8-eżametilindeno[5,6- c ]piran galassolid(HHCB)
Dutch Nederlands 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6- c ]pyran galaxolide(HHCB)
Polish polski 1,3,4,6,7,8-heksahydro-4,6,6,7,8,8-heksametyloindeno[5,6-c]piran galaxolid(HHCB)
Portuguese português 1,3,4,6,7,8-hexa-hidro-4,6,6,7,8,8-hexametilindeno[5,6- c ]pirano galaxolida(HHCB)
Romanian română 1,3,4,6,7,8-hexahidro-4,6,6,7,8,8-hexametilindeno[5,6- c ]piran galaxolid(HHCB)
Slovak slovenčina 4,6,6,7,8,8-hexametyl-1,3,4,6,7,8-hexahydroindeno[5,6-c]pyrán galaxolid(HHCB)
Slovenian slovenščina 1,3,4,6,7,8-heksahidro-4,6,6,7,8,8-heksametilindeno[5,6- c ]piran galaksolid(HHCB)
Finnish suomi 1,3,4,6,7,8-heksahydro-4,6,6,7,8,8-heksametyyli-indeno[5,6- c ]pyraani galaksolidi(HHCB)
Swedish svenska 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexametylindeno[5,6-c]pyran galaxolid(HHCB)

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

1,3,4,6,7,8-hexahydro-4,6,6,7… GHS label elements

Everything CLP Annex VI fixes for 1,3,4,6,7,8-hexahydro-4,6…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS09 Environment pictogram

Warning

1,3,4,6,7,8-hexahydro-4,6,6,7…

  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Avoid release to the environment.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 1,3,4,6,7,8-hexahydro-4,6… in the GHS label constructor →

07 · Health hazards

1,3,4,6,7,8-hexahydro-4,6,6,7… health hazards and exposure limits

1,3,4,6,7,8-hexahydro-4,6,6,7… hazard summary

Included in list of established contact allergens in humans; [EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)] A reproductive effector and moderate skin irritant; [RTECS]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

1,3,4,6,7,8-hexahydro-4,6,6,7… properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

1,3,4,6,7,8-hexahydro-4,6,6,7… boiling point

Property Value Conditions Source
Boiling point 128 °C (262.4 °F) at 0.8 mmHg (reduced pressure) HSDB

1,3,4,6,7,8-hexahydro-4,6,6,7… melting point

Property Value Conditions Source
Melting point 57.5 °C (135.5 °F) range, midpoint shown HSDB
-5 °C (23 °F) range, midpoint shown HSDB

1,3,4,6,7,8-hexahydro-4,6,6,7… density

Property Value Conditions Source
Density 1.087 g/cm³ HSDB
1.0054 g/cm³ at 20 °C HSDB
1.0035 g/cm³ range, midpoint shown, at 20 °C HSDB

1,3,4,6,7,8-hexahydro-4,6,6,7… solubility

Property Value Conditions Source
Solubility In water, 1.75 mg/L at 25 °C at 25 °C HSDB
In water, 1.65-1.99 mg/L at 25 °C and pH 5-9[ECHA; Search for Chemicals. 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexmethylindeno at 25 °C HSDB

1,3,4,6,7,8-hexahydro-4,6,6,7… vapor pressure

Property Value Conditions Source
Vapor pressure 0.000545 mmHg at 25 °C HSDB
0.00054 mmHg Haz-Map

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

1,3,4,6,7,8-hexahydro-4,6,6,7… storage and handling

1,3,4,6,7,8-hexahydro-4,6,6,7… storage conditions

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store under inert gas. Storage class (TRGS 510): Combustible liquids.[Sigma-Aldrich; Safety Data Sheet for 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8- hexamethylcyclopenta

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check 1,3,4,6,7,8-hexahydro-4,6… in the storage compatibility matrix →

10 · Questions

1,3,4,6,7,8-hexahydro-4,6,6,7… — frequently asked questions

What is the CAS number of 1,3,4,6,7,8-hexahydro-4,6,6,7…?

The CAS number of 1,3,4,6,7,8-hexahydro-4,6,6,7… is 1222-05-5. Its EC number is 214-946-9.

What does a 1,3,4,6,7,8-hexahydro-4,6,6,7… label have to show?

Under CLP Annex VI the label for 1,3,4,6,7,8-hexahydro-4,6,6,7… carries the pictogram Environment and the signal word is Warning.

Is 1,3,4,6,7,8-hexahydro-4,6,6,7… flammable?

CLP Annex VI assigns 1,3,4,6,7,8-hexahydro-4,6,6,7… no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is 1,3,4,6,7,8-hexahydro-4,6,6,7… a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for 1,3,4,6,7,8-hexahydro-4,6,6,7…. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of 1,3,4,6,7,8-hexahydro-4,6,6,7…?

The boiling point reported for 1,3,4,6,7,8-hexahydro-4,6,6,7… is 128 °C (262.4 °F), at 0.8 mmHg (reduced pressure) (HSDB).

What is the melting point of 1,3,4,6,7,8-hexahydro-4,6,6,7…?

The melting point reported for 1,3,4,6,7,8-hexahydro-4,6,6,7… is 57.5 °C (135.5 °F), range, midpoint shown (HSDB).

How should 1,3,4,6,7,8-hexahydro-4,6,6,7… be stored?

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store under inert gas. Storage class (TRGS 510): Combustible liquids.[Sigma-Aldrich; Safety Data Sheet for 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8- hexamethylcyclopenta (Hazardous Substances Data Bank (HSDB))

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