Substance profile
2,2',6,6'-tetrabromo–4,4'-isopropylidenediphenol
2,2',6,6'-tetrabromo–4,4'-isopropylidenediphenol is crystals from isopropyl alcohol and is odorless.
01 · Identification
What 2,2',6,6'-tetrabromo–4,4'-isop… is
2,2',6,6'-tetrabromo–4,4'-isopropylidenediphenol is crystals from isopropyl alcohol and is odorless. Its molecular formula is C15H12Br4O2 and its molecular weight is 543.9 g/mol. It boils at 316 °C, melts at 179 °C, is soluble in water.
Under the GHS it carries the signal word Danger.
02 · Identifiers
2,2',6,6'-tetrabromo–4,4'-isop… identifiers and molecular data
2,2',6,6'-tetrabromo–4,4'-isop… CAS number and EC number
2,2',6,6'-tetrabromo–4,4'-isop… molecular formula and molecular weight
Other names for 2,2',6,6'-tetrabromo–4,4'-isop…
- tetrabromobisphenol-A
03 · GHS classification
2,2',6,6'-tetrabromo–4,4'-isop… hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
2,2',6,6'-tetrabromo–4,4'-isop… pictograms and signal word
2,2',6,6'-tetrabromo–4,4'-isop… hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Carcinogenicity GHS chapter 3.6 | Category 1A or 1B | H350 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
2,2',6,6'-tetrabromo–4,4'-isop… hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H350 | May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to 2,2',6,6'-tetrabromo–4,4'…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 2,2',6,6'-tetrabromo–4,4'…
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2,2',6,6'-tetrabromo–4… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
2,2',6,6'-tetrabromo–4,4'-isop… precautionary statements
CLP Annex VI assigns 7 precautionary statements to 2,2',6,6'-tetrabromo–4,4'…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
2,2',6,6'-tetrabromo–4,4'-isop… name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 2,2’,6,6’-тетрабромо-4,4’-изопропилидендифенол тетрабромобисфенол-А |
| Spanish español | 2,2’,6,6’-Tetrabromo-4,4’-isopropilidendifenol tetrabromobisfenol-A |
| Czech čeština | 2,2‘,6,6’-tetrabrom-4,4’-isopropylidendifenol tetrabrombisfenol A |
| Danish dansk | 2,2',6,6'-tetrabrom-4,4'-isopropylidendiphenol tetrabrombisphenol-A |
| German Deutsch | 2,2‘,6,6’-Tetrabrom-4,4’-isopropylidenediphenol Tetrabrombisphenol-A |
| Estonian eesti | 2,2’,6,6’-tetrabromo-4,4’-isopropülideendifenool tetrabromobisfenool-A |
| Greek ελληνικά | 2,2′,6,6′-τετραβρωμο-4,4′-ισοπροπυλιδενοδιφαινόλη τετραβρωμοδισφαινόλη-A |
| English English | 2,2',6,6'-tetrabromo–4,4'-isopropylidenediphenol tetrabromobisphenol-A |
| French français | 2,2′,6,6′-tétrabromo-4,4′-isopropylidènediphénol tétrabromobisphénol-A |
| Croatian hrvatski | 2,2′,6,6′-tetrabrom- 4,4′-izopropilidendifenol tetrabrombisfenol-A |
| Italian italiano | 2,2’,6,6’-tetrabromo-4,4’-isopropilidendifenolo tetrabromobisfenol-A |
| Latvian latviešu | 2,2′,6,6′-tetrabrom-4,4′-izopropilidēndifenols tetrabrombisfenols-A |
| Lithuanian lietuvių | 2,2’,6,6’-tetrabromo-4,4’-izopropilidendifenolis tetrabrombisfenolis-A |
| Hungarian magyar | 2‚2’,6‚6’-tetrabróm-4‚4’-izopropilidéndifenol tetrabróm-biszfenol-A |
| Maltese Malti | 2,2’,6,6’-tetrabromo-4,4’-isopropilidenedifenol tetrabromobisfenol-A |
| Dutch Nederlands | 2,2,6,6'-tetrabroom-4,4'-isopropylidenedifenol tetrabroombisfenol-A |
| Polish polski | 2,2’,6,6’-tetrabromo-4,4’-izopropyloidenodifenol tetrabromobisfenol-A |
| Portuguese português | 2,2’,6,6’-tetrabromo-4,4’-isopropilidenodifenol tetrabromobisfenol-A |
| Romanian română | 2,2’,6,6’-tetrabromo-4,4’-isopropilidendifenol tetrabrombisfenol-A |
| Slovak slovenčina | 2,2‘,6‚6’-tetrabróm-4‚4’-izopropylidéndifenol tetrabrómbisfenol-A |
| Slovenian slovenščina | 2‚2’,6‚6’-tetrabromo-4‚4’-izopropilidendifenol tetrabromobisfenol-A |
| Finnish suomi | 2,2’,6,6’-tetrabromi-4,4’-isopropylideenidifenoli tetrabromibisfenoli-A |
| Swedish svenska | 2,2’,6,6’-tetrabrom-4,4’-isopropylidendifenol tetrabrombisfenol-A |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
2,2',6,6'-tetrabromo–4,4'-isop… GHS label elements
Everything CLP Annex VI fixes for 2,2',6,6'-tetrabromo–4,4'…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
2,2',6,6'-tetrabromo–4,4'-isop…
- May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Obtain special instructions before use.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF exposed or concerned:
- Get medical advice/attention.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 2,2',6,6'-tetrabromo–4,4'… in the GHS label constructor →
07 · Health hazards
2,2',6,6'-tetrabromo–4,4'-isop… health hazards and exposure limits
2,2',6,6'-tetrabromo–4,4'-isop… carcinogenicity classification
Under the conditions of these 2-year gavage studies, there was equivocal evidence of carcinogenic activity (see a summary of the Peer Review Panel comments and the public discussion on this Technical Report in Appendix N) of tetrabromobisphenol A in male Wistar Han rats based on the occurrence of testicular adenoma. There was clear evidence of carcinogenic activity of tetrabromobisphenol A in female Wistar Han rats based on increased incidences of uterine epithelial tumors (predominantly uterine adenocarcinoma). There was some evidence of carcinogenic activity of tetrabromobisphenol A in male B6C3F1/N mice based on increased incidences of hepatoblastoma. The increased incidences of large intestine neoplasms and hemangiosarcoma (all organs) may have been related to chemical administration. There was no evidence of carcinogenic activity of tetrabromobisphenol A in female B6C3F1/N mice administered 250 or 500 mg/kg.
Source: US National Toxicology Program · TR-587: Toxicology Studies of Tetrabromobisphenol A (CASRN 79-94-7) in F344/NTac Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Tetrabromobisphenol A in Wistar Han [Crl:WI(Han)] Rats and B6C3F1/N Mice (Gavage Studies) (2014 )
There is inadequate evidence in humans for the carcinogenicity of tetrabromobisphenol A. There is sufficient evidence in experimental animals for the carcinogenicity of tetrabromobisphenol A. Overall evaluation: Tetrabromobisphenol A is probably carcinogenic to humans (Group 2A).
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
2,2',6,6'-tetrabromo–4,4'-isop… properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
2,2',6,6'-tetrabromo–4,4'-isop… boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 316 °C (600.8 °F) | approximate | HSDB |
2,2',6,6'-tetrabromo–4,4'-isop… melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 179 °C (354.2 °F) | HSDB | |
| 180 °C (356 °F) | range, midpoint shown | HSDB | |
| 181.94 °C (359.5 °F) | range, midpoint shown | CAMEO |
2,2',6,6'-tetrabromo–4,4'-isop… density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 2.12 g/cm³ | HSDB | |
| 2.2 g/cm³ | at 4 °C | HSDB |
2,2',6,6'-tetrabromo–4,4'-isop… solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Soluble in ethanol, ether, benzene and chloroform | HSDB | |
| In water, 0.148 mg/L at pH 5; 1.26 mg/L at pH 7; 2.34 mg/L at pH 9, at 25 °C. In pure water, 0.063 mg/L at 21 °C; 0.24 mg/L at 25 °C | at 25 °C | HSDB |
2,2',6,6'-tetrabromo–4,4'-isop… vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 4.68e-8 mmHg | at 25 °C | HSDB |
2,2',6,6'-tetrabromo–4,4'-isop… flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 178 °C (352.4 °F) | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Source notes
Further notes on 2,2',6,6'-tetrabromo–4,4'-isop…
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Solubility
In water, 0.171 mg/L at 25 °C (non-ionic form, pH 3.05); 4.15 mg/L at 25 deg (pH 7.56); 30.5 mg/L at 25 deg (pH 7.99); 228 mg/L at 25 °C (pH 8.48); 1510 mg/L at 25 °C (pH 8.91)
Source: HSDB
10 · Handling and storage
2,2',6,6'-tetrabromo–4,4'-isop… storage and handling
2,2',6,6'-tetrabromo–4,4'-isop… storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Source: Hazardous Substances Data Bank (HSDB)
2,2',6,6'-tetrabromo–4,4'-isop… incompatible materials
Incompatible materials: Strong oxidizing agents.
Source: Hazardous Substances Data Bank (HSDB)
2,2',6,6'-tetrabromo–4,4'-isop… reactivity
TETRABROMOBISPHENOL A is monomer.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 2,2',6,6'-tetrabromo–4,4'… in the storage compatibility matrix →
11 · Questions
2,2',6,6'-tetrabromo–4,4'-isop… — frequently asked questions
What is the CAS number of 2,2',6,6'-tetrabromo–4,4'-isop…?
The CAS number of 2,2',6,6'-tetrabromo–4,4'-isop… is 79-94-7. Its EC number is 201-236-9.
What is the chemical formula of 2,2',6,6'-tetrabromo–4,4'-isop…?
The molecular formula of 2,2',6,6'-tetrabromo–4,4'-isop… is C15H12Br4O2 and its molecular weight is 543.9 g/mol.
What does a 2,2',6,6'-tetrabromo–4,4'-isop… label have to show?
Under CLP Annex VI the label for 2,2',6,6'-tetrabromo–4,4'-isop… carries the pictograms Health hazard and Environment and the signal word is Danger.
Is 2,2',6,6'-tetrabromo–4,4'-isop… flammable?
CLP Annex VI assigns 2,2',6,6'-tetrabromo–4,4'-isop… no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 178 °C (352.4 °F) (Haz-Map).
Is 2,2',6,6'-tetrabromo–4,4'-isop… a carcinogen?
Yes. CLP Annex VI classifies 2,2',6,6'-tetrabromo–4,4'-isop… as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 2A: probably carcinogenic to humans.
What is the boiling point of 2,2',6,6'-tetrabromo–4,4'-isop…?
The boiling point reported for 2,2',6,6'-tetrabromo–4,4'-isop… is 316 °C (600.8 °F), approximate (HSDB).
What is the melting point of 2,2',6,6'-tetrabromo–4,4'-isop…?
The melting point reported for 2,2',6,6'-tetrabromo–4,4'-isop… is 179 °C (354.2 °F) (HSDB).
How should 2,2',6,6'-tetrabromo–4,4'-isop… be stored?
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. (Hazardous Substances Data Bank (HSDB))
Nearby
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