Substance profile
2,4,5-T (ISO)
2,4,5-T (ISO) is a white solid and is odorless.
01 · Identification
What 2,4,5-T (ISO) is
2,4,5-T (ISO) is a white solid and is odorless. It melts at 153 °C.
Under the GHS it carries the signal word Warning. It is classed as carcinogens.
02 · Identifiers
2,4,5-T (ISO) identifiers and molecular data
2,4,5-T (ISO) CAS number and EC number
2,4,5-T (ISO) molecular formula and molecular weight
Other names for 2,4,5-T (ISO)
- 2,4,5-trichlorophenoxy acetic acid
03 · GHS classification
2,4,5-T (ISO) hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
2,4,5-T (ISO) pictograms and signal word
2,4,5-T (ISO) hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 2 | H315 | GHS07 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 | H335 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
2,4,5-T (ISO) hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H302 | Harmful if swallowed. |
| H335 | May cause respiratory irritation. |
| H315 | Causes skin irritation. |
| H319 | Causes serious eye irritation. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to 2,4,5-T (ISO). The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 2,4,5-T (ISO)
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2,4,5-T (ISO) issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
2,4,5-T (ISO) precautionary statements
CLP Annex VI assigns 16 precautionary statements to 2,4,5-T (ISO). They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
2,4,5-T (ISO) name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 2,4,5-T (ISO) 2,4,5-трихлорофеноксиоцетна киселина |
| Spanish español | 2,4,5-T (ISO) ácido 2,4,5-triclorofenoxiacético |
| Czech čeština | 2,4,5-T (ISO) (2,4,5-trichlorfenoxy)octová kyselina |
| Danish dansk | 2,4,5-T 2,4,5-trichlorphenoxyeddikesyre |
| German Deutsch | 2,4,5-T (ISO) 2,4,5-Trichlorphenoxyessigsäure |
| Estonian eesti | 2,4,5-T (ISO) 2,4,5-triklorofenoksüäädikhape |
| Greek ελληνικά | 2,4,5-T (ISO) 2,4,5-τριχλωροφαινοξυοξικό οξύ |
| English English | 2,4,5-T (ISO) 2,4,5-trichlorophenoxy acetic acid |
| French français | 2,4,5-T (ISO) acide 2,4,5-trichlorophénoxyacétique |
| Croatian hrvatski | 2,4,5-T (ISO) 2,4,5-triklorfenoksioctena kiselina |
| Italian italiano | acido 2,4,5-triclorofenossiacetico |
| Latvian latviešu | 2,4,5-T (ISO) 2,4,5-trihlorfenoksietiķskābe |
| Lithuanian lietuvių | 2,4,5-T (ISO) 2,4,5-trichlorfenoksiacto rūgštis |
| Hungarian magyar | 2,4,5-T (ISO) 2,4,5-triklórfenoxiecetsav |
| Maltese Malti | 2,4,5-T (ISO) aċidu aċetiku ta’ 2,4,5-triklorofenossi |
| Dutch Nederlands | 2,4,5-T (ISO) 2,4,5-trichloorfenoxyazijnzuur |
| Polish polski | 2,4,5-T (ISO) kwas (2,4,5-trichlorofenoksy)octowy |
| Portuguese português | 2,4,5-T (ISO) ácido 2,4,5-triclorofenoxiacético |
| Romanian română | 2,4,5-T (ISO) acid 2,4,5-triclorofenoxiacetic |
| Slovak slovenčina | 2,4,5-T (ISO) kyselina (2,4,5-trichlórfenoxy)octová |
| Slovenian slovenščina | 2,4,5-T (ISO) 2,4,5-triklorofenoksiocetna kislina |
| Finnish suomi | 2,4,5-T (ISO) 2,4,5-trikloorifenoksietikkahappo |
| Swedish svenska | 2,4,5-T (ISO) 2,4,5-triklorfenoxiättiksyra |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
2,4,5-T (ISO) GHS label elements
Everything CLP Annex VI fixes for 2,4,5-T (ISO), laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
2,4,5-T (ISO)
- Harmful if swallowed.
- May cause respiratory irritation.
- Causes skin irritation.
- Causes serious eye irritation.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Wash … thoroughly after handling.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF IN EYES:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Rinse mouth.
- If skin irritation occurs:
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 2,4,5-T (ISO) in the GHS label constructor →
07 · Health hazards
2,4,5-T (ISO) health hazards and exposure limits
2,4,5-T (ISO) hazard summary
2,4,5-T is toxic to the liver in acute animal studies. Epidemiology studies found no evidence that 2,4,5-T is teratogenic to exposed workers. [ACGIH] There is limited positive evidence that 2,4,5-T causes birth defects in animals. There is strong negative data that it causes skeletal defects in humans. [ATSDR Case Studies #29] Overall, it appears that the chlorophenoxy herbicides have led to little or no hepatic injury. Where sufficient occupational exposure seems to have led to hepatic abnormalities (e.g., toxic porphyria), the presumed chemical culprit has been the contaminating TCDD, rather than the herbicide per se. [Zimmerman, p. 415] In poisoning cases by ingestion of chlorophenoxy compounds, elevated liver enzymes and rhabdomyolysis with secondary renal failure have been reported; [HSDB]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
2,4,5-T (ISO) carcinogenicity classification
Classification of carcinogenicity: 1) evidence in humans: limited; Overall summary evaluation of carcinogenic risk to humans is Group 2B: The agent is possibly carcinogenic to humans. /Chlorophenoxy herbicides; From table/
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
2,4,5-T (ISO) occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | 10.0 [mg/m3] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| PEL | 10 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| PEL | TWA 10 mg/m3 | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | 10 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| REL | TWA 10 mg/m3 | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | 250 mg/m3 (NIOSH, 2024) | CAMEO Chemicals |
| IDLH | 250.0 [mg/m3] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| IDLH | 250 mg/cu m | Hazardous Substances Data Bank (HSDB) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
2,4,5-T (ISO) properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
2,4,5-T (ISO) boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | Decomposes | decomposes | HSDB |
| Decomposes (NTP, 1992) | decomposes | CAMEO |
2,4,5-T (ISO) melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 153 °C (307.4 °F) | HSDB | |
| 152.78 °C (307 °F) | NIOSH | ||
| 157.78 °C (316 °F) | CAMEO |
2,4,5-T (ISO) density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.8 g/cm³ | NIOSH | |
| 1.8 g/cm³ | at 20 °C | HSDB | |
| 1.803 g/cm³ | at 20 °C | CAMEO |
2,4,5-T (ISO) solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | VERY SLIGHTLY SOL IN PETROLEUM ETHER | HSDB | |
| 590 MG/KG IN ETHANOL OR ISOPROPYL ALC | HSDB | ||
| 0.028% AT 25 °C | at 25 °C | HSDB |
2,4,5-T (ISO) vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 1e-7 mmHg | NIOSH | |
| 0 mmHg | at 20 °C | CAMEO |
2,4,5-T (ISO) lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | available on MS-DOS floppy disketts (3.5" of 5.25") | HSDB | |
| Combustible Solid, but burns with difficulty. | NIOSH |
2,4,5-T (ISO) corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | Non-corrosive, but some oil based formulations may be deleterious to painted surfaces. | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
2,4,5-T (ISO) fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
2,4,5-T (ISO) fire potential
Material does not burn or burns with difficulty.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
2,4,5-T (ISO) storage and handling
2,4,5-T (ISO) safe storage
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store in an area without drain or sewer access.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
2,4,5-T (ISO) storage conditions
DO NOT STORE NEAR OTHER AGROCHEMICALS OR SEEDS. DO NOT STORE IN FREEZING TEMPERATURES.
Source: Hazardous Substances Data Bank (HSDB)
2,4,5-T (ISO) incompatible materials
None reported
Source: The National Institute for Occupational Safety and Health (NIOSH)
2,4,5-T (ISO) reactivity
2,4,5-TRICHLOROPHENOXYACETIC ACID is a weak acid. Reacts with organic and inorganic bases to form water-soluble salts and with alcohols to form esters. Incompatible with strong oxidizing agents and strong bases. Can corrode metals, especially if moist. May harm painted surfaces (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 2,4,5-T (ISO) in the storage compatibility matrix →
11 · Questions
2,4,5-T (ISO) — frequently asked questions
What is the CAS number of 2,4,5-T (ISO)?
The CAS number of 2,4,5-T (ISO) is 93-76-5. Its EC number is 202-273-3.
What does a 2,4,5-T (ISO) label have to show?
Under CLP Annex VI the label for 2,4,5-T (ISO) carries the pictograms Exclamation mark and Environment and the signal word is Warning.
Is 2,4,5-T (ISO) flammable?
CLP Annex VI assigns 2,4,5-T (ISO) no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is 2,4,5-T (ISO) a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 2,4,5-T (ISO). Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the exposure limit for 2,4,5-T (ISO)?
The US occupational exposure limit reported for 2,4,5-T (ISO) is 10.0 [mg/m3] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of 2,4,5-T (ISO)?
The boiling point reported for 2,4,5-T (ISO) is Decomposes, decomposes (HSDB).
What is the melting point of 2,4,5-T (ISO)?
The melting point reported for 2,4,5-T (ISO) is 153 °C (307.4 °F) (HSDB).
How should 2,4,5-T (ISO) be stored?
DO NOT STORE NEAR OTHER AGROCHEMICALS OR SEEDS. DO NOT STORE IN FREEZING TEMPERATURES. (Hazardous Substances Data Bank (HSDB))
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