Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

2-Naphthylamine

2-Naphthylamine is colorless crystals which darken in air to a reddish-purple color with a faint aromatic odor.

CAS 91-59-8 C10H9N 143.18 g/mol Danger

01 · Identification

What 2-Naphthylamine is

2-Naphthylamine is colorless crystals which darken in air to a reddish-purple color with a faint aromatic odor. Its molecular formula is C10H9N and its molecular weight is 143.18 g/mol. It boils at 306 °C, melts at 110 °C, is soluble in water.

Under the GHS it carries the signal word Danger. It is classed as carcinogens.

02 · Identifiers

2-Naphthylamine identifiers and molecular data

2-Naphthylamine CAS number and EC number

CAS number91-59-8
EC number202-080-4
Index number (CLP Annex VI)612-022-00-3

2-Naphthylamine molecular formula and molecular weight

Molecular formulaC10H9N
Molecular weight143.18 g/mol
Chemical class Carcinogens

03 · GHS classification

2-Naphthylamine hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

2-Naphthylamine pictograms and signal word

Signal wordDanger

2-Naphthylamine hazard class and category

GHS hazard classes 2-Naphthylamine falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Carcinogenicity GHS chapter 3.6 Category 1A or 1B H350 GHS08
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 2 H411 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

2-Naphthylamine hazard statements (H-codes)

Hazard statements assigned to 2-Naphthylamine
CodeHazard statement
H350 May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H302 Harmful if swallowed.
H411 Toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to 2-Naphthylamine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 2-Naphthylamine

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2-Naphthylamine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

2-Naphthylamine precautionary statements

CLP Annex VI assigns 11 precautionary statements to 2-Naphthylamine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

2-Naphthylamine name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български 2-нафтиламин
Spanish español 2-Naftilamina
Czech čeština 2-naftylamin
Danish dansk 2-naphthylamin
German Deutsch 2-Naphthylamin β-Naphthylamin
Estonian eesti 2-naftüülamiin
Greek ελληνικά 2-ναφθυλαμίνη
English English 2-naphthylamine
French français 2-naphtylamine
Croatian hrvatski 2-naftilamin
Italian italiano 2-naftilamina
Latvian latviešu 2-naftilamīns
Lithuanian lietuvių 2-naftilaminas
Hungarian magyar 2-naftilamin
Maltese Malti 2-naftilammina
Dutch Nederlands 2-naftylamine
Polish polski 2-naftyloamina
Portuguese português 2-naftilamina
Romanian română 2-naftilamină
Slovak slovenčina 2-naftylamín
Slovenian slovenščina 2-naftilamin
Finnish suomi 2-naftyyliamiini
Swedish svenska 2-naftylamin

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

2-Naphthylamine GHS label elements

Everything CLP Annex VI fixes for 2-Naphthylamine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS07 Exclamation mark pictogramGHS09 Environment pictogram

Danger

2-Naphthylamine

  • May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Harmful if swallowed.
  • Toxic to aquatic life with long lasting effects.
  • Obtain special instructions before use.
  • Do not eat, drink or smoke when using this product.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF exposed or concerned:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Get medical advice/attention.
  • Rinse mouth.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 2-Naphthylamine in the GHS label constructor →

07 · Health hazards

2-Naphthylamine health hazards and exposure limits

2-Naphthylamine hazard summary

A bladder carcinogen regulated by OSHA; see 29 CFR 1910.1003; Listed in the table Examples of Industrial Chemicals for Which Methemoglobin Formation is NOT the Principal Cause of Toxicity; [ACGIH] See alpha-Naphthylamine.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

2-Naphthylamine carcinogenicity classification

IARC classification Group 1 — Carcinogenic to humans
IARC monographs Volume 4: (1974) Some Aromatic Amines, Hydrazine and Related Substances, N-Nitroso Compounds and Miscellaneous Alkylating Agents; Volume 99: (2010) Some Aromatic Amines, Organic Dyes, and Related Exposures

Sufficient evidence of carcinogenicity in humans. Sufficient evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 1: The agent is a human carcinogen. /From table/

Source: Hazardous Substances Data Bank (HSDB)

2-Naphthylamine: known to be a human carcinogen.

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

2-Naphthylamine occupational exposure limits

US occupational exposure limits reported for 2-Naphthylamine. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL Ca Occupational Safety and Health Administration (OSHA)
PEL [1910.1009] See Appendix B The National Institute for Occupational Safety and Health (NIOSH)
REL Ca See Appendix A The National Institute for Occupational Safety and Health (NIOSH)
IDLH A potential occupational carcinogen. (NIOSH, 2024) CAMEO Chemicals
IDLH NIOSH considers beta-naphthylamine to be a potential occupational carcinogen. Hazardous Substances Data Bank (HSDB)
IDLH Ca [N.D.] The National Institute for Occupational Safety and Health (NIOSH)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

2-Naphthylamine properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

2-Naphthylamine boiling point

Property Value Conditions Source
Boiling point 306 °C (582.8 °F) HSDB
306.11 °C (583 °F) NIOSH
306.11 °C (583 °F) at 760 mmHg CAMEO

2-Naphthylamine melting point

Property Value Conditions Source
Melting point 109.5 °C (229.1 °F) Technical HSDB
111.11 °C (232 °F) NIOSH

2-Naphthylamine density

Property Value Conditions Source
Density 1.061 g/cm³ ICSC
1.061 g/cm³ at 98 °C HSDB
1.061 g/cm³ at 97.78 °C CAMEO

2-Naphthylamine solubility

Property Value Conditions Source
Solubility Soluble in alcohol, ether HSDB
SOL IN MANY ORG SOLVENTS HSDB
In water, 6.40 mg/L @ 18 °C at 18 °C HSDB

2-Naphthylamine vapor pressure

Property Value Conditions Source
Vapor pressure 0.000256 mmHg at 25 °C HSDB
1 mmHg at 107.78 °C NIOSH
1 mmHg at 108 °C CAMEO

2-Naphthylamine flash point

Property Value Conditions Source
Flash point 157 °C (314.6 °F) HSDB
157.22 °C (315 °F) NIOSH

2-Naphthylamine lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) Nonexplosive HSDB
Combustible Solid NIOSH

2-Naphthylamine vapor density

Property Value Conditions Source
Vapor density 4.95 (air = 1) HSDB

2-Naphthylamine odor threshold

Property Value Conditions Source
Odor threshold Recognition: 1.4-1.9 mg/cu m HSDB
Odor Threshold Low: 1.4 [ppm] Haz-Map
Odor Threshold High: 1.9 [ppm] Haz-Map

2-Naphthylamine corrosivity

Property Value Conditions Source
Corrosivity NOT CORROSIVE HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

2-Naphthylamine fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

2-Naphthylamine fire potential

It is combustible and at elevated temperatures evolves a vapor which is flammable ... Fire hazard: moderate, when exposed to heat or flame.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

2-Naphthylamine storage and handling

2-Naphthylamine safe storage

Separated from food and feedstuffs. Well closed. Store in an area without drain or sewer access.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

2-Naphthylamine storage conditions

Separated from food and feedstuffs. Well closed.

Source: Hazardous Substances Data Bank (HSDB)

2-Naphthylamine incompatible materials

None reported

Source: The National Institute for Occupational Safety and Health (NIOSH)

2-Naphthylamine reactivity

BETA-NAPHTHYLAMINE is a weak base. It is incompatible with strong oxidizing agents and strong acids. It is also incompatible with nitrous acid. It reduces warm ammoniacal silver nitrate. (NTP, 1992)

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 2-Naphthylamine in the storage compatibility matrix →

11 · Questions

2-Naphthylamine — frequently asked questions

What is the CAS number of 2-Naphthylamine?

The CAS number of 2-Naphthylamine is 91-59-8. Its EC number is 202-080-4.

What is the chemical formula of 2-Naphthylamine?

The molecular formula of 2-Naphthylamine is C10H9N and its molecular weight is 143.18 g/mol.

What does a 2-Naphthylamine label have to show?

Under CLP Annex VI the label for 2-Naphthylamine carries the pictograms Health hazard, Exclamation mark and Environment and the signal word is Danger.

Is 2-Naphthylamine flammable?

CLP Annex VI assigns 2-Naphthylamine no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 157 °C (314.6 °F) (HSDB).

Is 2-Naphthylamine a carcinogen?

Yes. CLP Annex VI classifies 2-Naphthylamine as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 1: carcinogenic to humans.

What is the exposure limit for 2-Naphthylamine?

The US occupational exposure limit reported for 2-Naphthylamine is Ca (Occupational Safety and Health Administration (OSHA)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of 2-Naphthylamine?

The boiling point reported for 2-Naphthylamine is 306 °C (582.8 °F) (HSDB).

What is the melting point of 2-Naphthylamine?

The melting point reported for 2-Naphthylamine is 109.5 °C (229.1 °F), Technical (HSDB).

How should 2-Naphthylamine be stored?

Separated from food and feedstuffs. Well closed. (Hazardous Substances Data Bank (HSDB))

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