Substance profile
4-chloro-o-cresol
4-chloro-o-cresol is needles from petroleum ether with a mild, phenolic odor.
01 · Identification
What 4-chloro-o-cresol is
4-chloro-o-cresol is needles from petroleum ether with a mild, phenolic odor. It boils at 223 °C, melts at 51 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
4-chloro-o-cresol identifiers and molecular data
4-chloro-o-cresol CAS number and EC number
Other names for 4-chloro-o-cresol
- 4-chloro-2-methyl phenol
03 · GHS classification
4-chloro-o-cresol hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
4-chloro-o-cresol pictograms and signal word
4-chloro-o-cresol hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - inhalation GHS chapter 3.1 | Category 3 | H331 | GHS06 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 1A or 1B or 1C | H314 | GHS05 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
4-chloro-o-cresol hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H331 | Toxic if inhaled. |
| H314 | Causes severe skin burns and eye damage. |
| H400 | Very toxic to aquatic life. |
This page lists only the codes assigned to 4-chloro-o-cresol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 4-chloro-o-cresol
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 4-chloro-o-cresol issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
4-chloro-o-cresol precautionary statements
CLP Annex VI assigns 10 precautionary statements to 4-chloro-o-cresol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
4-chloro-o-cresol name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 4-хлоро- o -крезол 2-метил-4-хлорофенол |
| Spanish español | 4-Cloro- o -cresol 4-cloro-2-metilfenol |
| Czech čeština | 4-chlor- o -kresol 4-chlor-2-methylfenol |
| Danish dansk | 4-chlor- o -cresol 4-chlor-2-methylphenol |
| German Deutsch | 4-Chlor- o -kresol 4-Chlor-2-methylphenol |
| Estonian eesti | 4-kloro- o -kresool 4-kloro-2-metüülfenool |
| Greek ελληνικά | 4-χλωρο- o -κρεσόλη 4-χλωρο-2-μεθυλοφαινόλη |
| English English | 4-chloro- o -cresol 4-chloro-2-methylphenol |
| French français | 4-chloro- o -crésol 4-chloro-2-méthylphénol |
| Croatian hrvatski | 4-klor- o -krezol 4-klor-2-metilfenol |
| Italian italiano | 4-cloro-o-cresolo 4-cloro-2-metilfenolo |
| Latvian latviešu | 4-hlor- o -krezols 4-hlor-2-metilfenols |
| Lithuanian lietuvių | 4-chlor- o -krezolis 4-chlor-2-metilfenolis |
| Hungarian magyar | 4-klór- o -krezol 4-klór-2-metilfenol |
| Maltese Malti | 4-kloro- o -kreżol 4-kloro-2-metilfenol |
| Dutch Nederlands | 4-chloor- o -cresol 4-chloor-2-methylfenol |
| Polish polski | 4-chloro- o -krezol 4-chloro-2-metylofenol |
| Portuguese português | 4-cloro- o -cresol 4-cloro-2-metilfenol |
| Romanian română | 4-cloro- o -crezol 4-cloro-2-metilfenol |
| Slovak slovenčina | 4-chlór-orto-krezol 4-chlór-2-metylfenol |
| Slovenian slovenščina | 4-kloro- o -krezol 4-kloro-2-metilfenol |
| Finnish suomi | 4-kloori-o-kresoli 4-kloori-2-metyylifenoli |
| Swedish svenska | 4-klor- o -kresol 4-klor-2-metylfenol |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
4-chloro-o-cresol GHS label elements
Everything CLP Annex VI fixes for 4-chloro-o-cresol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
4-chloro-o-cresol
- Toxic if inhaled.
- Causes severe skin burns and eye damage.
- Very toxic to aquatic life.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Use only outdoors or in a well-ventilated area.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF INHALED:
- Immediately call a POISON CENTER/doctor/…
- Do NOT induce vomiting.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 4-chloro-o-cresol in the GHS label constructor →
07 · Health hazards
4-chloro-o-cresol health hazards and exposure limits
4-chloro-o-cresol hazard summary
A skin, eye, and mucous membrane irritant; [CAMEO] A corrosive substance that can cause injury to the skin and eyes, based on animal studies; [CHEMINFO] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Can cause pulmonary edema; [ICSC] Chlorocresol causes contact urticaria (both immune and non-immune); [Kanerva, p. 219] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline] See CHLOROPHENOLS. See p-Chloro-m-cresol.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
4-chloro-o-cresol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
4-chloro-o-cresol boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 223 °C (433.4 °F) | HSDB | |
| 231 °C (447.8 °F) | ICSC | ||
| 223.61 °C (434.5 °F) | range, midpoint shown, at 760 mmHg | CAMEO |
4-chloro-o-cresol melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 51 °C (123.8 °F) | HSDB | |
| 49.44 °C (121 °F) | range, midpoint shown | CAMEO | |
| 48 °C (118.4 °F) | range, midpoint shown | ICSC |
4-chloro-o-cresol density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.2 g/cm³ | HSDB | |
| 0.48 g/cm³ | ICSC |
4-chloro-o-cresol solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Sol in petroleum ether | HSDB | |
| Solubility in water, g/100ml at 20 °C: 0.23 | at 20 °C | ICSC | |
| In water, 4.00X10+3 mg/l @ 25 °C | at 25 °C | HSDB |
4-chloro-o-cresol vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.2025 mmHg | at 20 °C | ICSC |
| 0.024 mmHg | at 25 °C | HSDB | |
| 0.02 mmHg | Haz-Map |
4-chloro-o-cresol flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 112.78 °C (235 °F) | above this value | CAMEO |
| 78 °C (172.4 °F) | Haz-Map |
4-chloro-o-cresol odor threshold
| Property | Value | Conditions | Source |
|---|---|---|---|
| Odor threshold | Odor detection threshold= 1,800 ug/l at 20-22 °C | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
4-chloro-o-cresol storage and handling
4-chloro-o-cresol incompatible materials
A large quantitiy (700 kg) of /4-chloro-2-methylphenol/, left in contact with concentrated sodium hydroxide soln for 3 days, decomposed, attaining red heat and evolving fumes which ignited explosively. Although this could not be reproduced under laboratory conditions, it is believed that exothermic hydrolysis to the hydroquinone (possibly with subsequent aerobic oxidation to the quinone) occurred, the high viscosity of the liquid preventing dissipation of heat.
Source: Hazardous Substances Data Bank (HSDB)
4-chloro-o-cresol reactivity
P-CHLORO-O-CRESOL can react vigorously with concentrated sodium hydroxide solutions. Also reacts with other bases, acid chlorides, acid anhydrides, and oxidizing agents. Corrodes steel, brass, copper and copper alloys [NTP, 1992)]. A large quantity left in contact with concentrated sodium hydroxide solution for 3 days reacted violently, attaining red heat and evolving fumes that ignited explosively. The heat of reaction dissipated poorly because of the high viscosity of the mixture [Quart. Safety Summ., 1957, 28, 39].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 4-chloro-o-cresol in the storage compatibility matrix →
10 · Questions
4-chloro-o-cresol — frequently asked questions
What is the CAS number of 4-chloro-o-cresol?
The CAS number of 4-chloro-o-cresol is 1570-64-5. Its EC number is 216-381-3.
What does a 4-chloro-o-cresol label have to show?
Under CLP Annex VI the label for 4-chloro-o-cresol carries the pictograms Skull and crossbones, Corrosion and Environment and the signal word is Danger.
Is 4-chloro-o-cresol flammable?
CLP Annex VI assigns 4-chloro-o-cresol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 112.78 °C (235 °F), above this value (CAMEO).
Is 4-chloro-o-cresol a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 4-chloro-o-cresol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of 4-chloro-o-cresol?
The boiling point reported for 4-chloro-o-cresol is 223 °C (433.4 °F) (HSDB).
What is the melting point of 4-chloro-o-cresol?
The melting point reported for 4-chloro-o-cresol is 51 °C (123.8 °F) (HSDB).
Nearby
Substances next to 4-chloro-o-cresol
Keep going: substances starting with 0–9, or search the whole database by name, CAS number, pictogram or signal word.