Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

4-isocyanatosulphonyltoluene

4-isocyanatosulphonyltoluene: liquid.

CAS 4083-64-1 C8H7NO3S 197.21 g/mol Danger

01 · Identification

What 4-isocyanatosulphonyltoluene is

4-isocyanatosulphonyltoluene: liquid. Its molecular formula is C8H7NO3S and its molecular weight is 197.21 g/mol.

Under the GHS it carries the signal word Danger.

02 · Identifiers

4-isocyanatosulphonyltoluene identifiers and molecular data

4-isocyanatosulphonyltoluene CAS number and EC number

CAS number4083-64-1
EC number223-810-8
Index number (CLP Annex VI)615-012-00-7

4-isocyanatosulphonyltoluene molecular formula and molecular weight

Molecular formulaC8H7NO3S
Molecular weight197.21 g/mol

Other names for 4-isocyanatosulphonyltoluene

  • tosyl isocyanate

03 · GHS classification

4-isocyanatosulphonyltoluene hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

4-isocyanatosulphonyltoluene pictograms and signal word

Signal wordDanger

4-isocyanatosulphonyltoluene hazard class and category

GHS hazard classes 4-isocyanatosulphonyltolue… falls into
Hazard class Category From code Pictogram
Skin corrosion/irritation GHS chapter 3.2 Category 2 H315 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Respiratory sensitisation GHS chapter 3.4 Category 1 or 1A or 1B H334 GHS08
Specific target organ toxicity - single exposure GHS chapter 3.8 Category 3 H335 GHS07

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

4-isocyanatosulphonyltoluene hazard statements (H-codes)

Hazard statements assigned to 4-isocyanatosulphonyltolue…
CodeHazard statement
H335 May cause respiratory irritation.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.

4-isocyanatosulphonyltoluene supplemental EU statements (EUH)

EU-specific statements assigned to 4-isocyanatosulphonyltolue…. They exist only in CLP and have no counterpart in UN GHS.
CodeStatement
EUH014 Reacts violently with water.

This page lists only the codes assigned to 4-isocyanatosulphonyltolue…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 4-isocyanatosulphonyltolue…

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 4-isocyanatosulphonylt… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

4-isocyanatosulphonyltoluene precautionary statements

CLP Annex VI assigns 16 precautionary statements to 4-isocyanatosulphonyltolue…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

4-isocyanatosulphonyltoluene name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български 4-изоцианатосулфонилтолуен тозилов изоцианат
Spanish español 4-Isocianatosulfoniltolueno isocianato de tosilo
Czech čeština (4-methylbenzensulfonyl)isokyanát tosyl-isokyanát
Danish dansk 4-toluensulfonylisocyanat tosylisocyanat
German Deutsch 4-Toluolsulfonylisocyanat Tosylisocyanat
Estonian eesti 4-isotsüanatosulfonüültolueen tosüülisotsüanaat
Greek ελληνικά 4-ισοκυανοσουλφονυλοτολουόλιο ισοκυανικό τοσύλιο
English English 4-isocyanatosulphonyltoluene tosyl isocyanate
French français 4-isocyanatosulfonyltoluène isocyanate de tosyle
Croatian hrvatski 4-izocijanatosulfoniltoluen tosil izocijanat
Italian italiano 4-isocianatosulfonil-toluene tosilisocianato
Latvian latviešu 4-izocianatosulfoniltoluols tozilizocianāts
Lithuanian lietuvių 4-toluensulfonilizocianatas tozilizocianatas
Hungarian magyar 4-izocianát-szulfonil-toluol tozil-izocianát
Maltese Malti 4-isoċjanatosulfoniltoluwen isoċjanat tat-tosil
Dutch Nederlands 4-isocyanatosulfonyl-tolueen tosylisocyanaat
Polish polski 4-izocyjanianosulfonylotoluen 4-izocyjanian toluenosulfonyluizocyjanian tosylu
Portuguese português 4-isocianatossulfoniltolueno isocianato de tosilo
Romanian română 4-izocianatosulfoniltoluen izocianat de tosil
Slovak slovenčina (4-metylfenylsulfonyl)izokyanát tozylizokyanát
Slovenian slovenščina 4-izocianatosulfoniltoluen tozil izocianat
Finnish suomi tosyyli-isosyanaatti p-tolueenisulfonyyli-isosyanaatti
Swedish svenska 4-isocyanatosulfonyltoluen tosylisocyanat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

4-isocyanatosulphonyltoluene GHS label elements

Everything CLP Annex VI fixes for 4-isocyanatosulphonyltolue…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS07 Exclamation mark pictogram

Danger

4-isocyanatosulphonyltoluene

  • May cause respiratory irritation.
  • Causes skin irritation.
  • Causes serious eye irritation.
  • May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • Reacts violently with water.
  • Obtain special instructions before use.
  • Avoid breathing dust/fume/gas/mist/vapours/spray.
  • Wash thoroughly after handling.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • [In case of inadequate ventilation] wear respiratory protection.
  • IF ON SKIN:
  • IF INHALED:
  • IF IN EYES:
  • Call a POISON CENTER/doctor/
  • Get medical advice/attention.
  • If skin irritation occurs:
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Remove person to fresh air and keep comfortable for breathing.
  • If experiencing respiratory symptoms:
  • Wash with plenty of water/

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 4-isocyanatosulphonyltolue… in the GHS label constructor →

07 · Health hazards

4-isocyanatosulphonyltoluene health hazards and exposure limits

4-isocyanatosulphonyltoluene hazard summary

A mild skin and moderate eye irritant; Causes changes in leukocyte count and changes in liver and kidney weights in 42-day constant oral studies of rats; [RTECS] Highly reactive; Hydrolyses rapidly forming p-toluenesulfonamide (CAS# 70-55-3) and carbon dioxide; [EPA ChAMP: Submission] Reacts violently with water; A skin and strong eye irritant; May cause respiratory sensitization; [Alfa Aesar MSDS] Search for (4083-64-1[EC/RN Number]) AND (asthma OR dermatitis OR allergic OR sensitizer OR sensitization): no results; [PubMed] See p-Toluenesulfonamide.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Questions

4-isocyanatosulphonyltoluene — frequently asked questions

What is the CAS number of 4-isocyanatosulphonyltoluene?

The CAS number of 4-isocyanatosulphonyltoluene is 4083-64-1. Its EC number is 223-810-8.

What is the chemical formula of 4-isocyanatosulphonyltoluene?

The molecular formula of 4-isocyanatosulphonyltoluene is C8H7NO3S and its molecular weight is 197.21 g/mol.

What does a 4-isocyanatosulphonyltoluene label have to show?

Under CLP Annex VI the label for 4-isocyanatosulphonyltoluene carries the pictograms Health hazard and Exclamation mark and the signal word is Danger.

Is 4-isocyanatosulphonyltoluene flammable?

CLP Annex VI assigns 4-isocyanatosulphonyltoluene no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is 4-isocyanatosulphonyltoluene a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for 4-isocyanatosulphonyltoluene. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

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