Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Benzene

Benzene is a clear, colorless liquid with an aromatic odor.

CAS 71-43-2 C6H6 78.11 g/mol Danger

Benzene Safety Data Sheet →

01 · Identification

What Benzene is

Benzene is a clear, colorless liquid with an aromatic odor. Its molecular formula is C6H6 and its molecular weight is 78.11 g/mol. It boils at 80.1 °C, melts at 5.6 °C.

Under the GHS it carries the signal word Danger. It is classed as hazardous Air Pollutants (HAPs).

02 · Identifiers

Benzene identifiers and molecular data

Benzene CAS number and EC number

CAS number71-43-2
EC number200-753-7
Index number (CLP Annex VI)601-020-00-8

Benzene molecular formula and molecular weight

Molecular formulaC6H6
Molecular weight78.11 g/mol
Chemical class Hazardous Air Pollutants (HAPs)

Other names for Benzene

  • benzol
  • C6H6
  • (6)Annulene
  • Benzin
  • Benzine
  • Benzole
  • Benzolene
  • Bicarburet Of Hydrogen
  • Carbon Oil
  • Coal Naphtha
  • Cyclohexatriene
  • 1,3,5-Cyclohexatriene
  • Mineral Naphtha
  • Motor Benzol

03 · GHS classification

Benzene hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Benzene pictograms and signal word

Signal wordDanger

Benzene hazard class and category

GHS hazard classes Benzene falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 2 H225 GHS02
Skin corrosion/irritation GHS chapter 3.2 Category 2 H315 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Germ cell mutagenicity GHS chapter 3.5 Category 1A or 1B H340 GHS08
Carcinogenicity GHS chapter 3.6 Category 1A or 1B H350 GHS08
Specific target organ toxicity - repeated exposure GHS chapter 3.9 Category 1 H372 GHS08
Aspiration hazard GHS chapter 3.10 Category 1 H304 GHS08

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Benzene hazard statements (H-codes)

Hazard statements assigned to Benzene
CodeHazard statement
H225 Highly flammable liquid and vapour.
H350 May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H340 May cause genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H304 May be fatal if swallowed and enters airways.
H372 Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H315 Causes skin irritation.
H319 Causes serious eye irritation.

This page lists only the codes assigned to Benzene. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Benzene

Our own Benzene safety data sheet walks through all sixteen sections of the published data. What it is not is the document an inspector asks for: an SDS is issued for a product by its supplier, so the sheet covering the grade actually standing in your store exists only in that supplier’s version. Collecting those and keeping them current as suppliers revise them is a separate job.

04 · Precautionary statements

Benzene precautionary statements

CLP Annex VI assigns 19 precautionary statements to Benzene. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Benzene name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български бензен
Spanish español Benceno
Czech čeština benzen
Danish dansk benzen
German Deutsch Benzol
Estonian eesti benseen
Greek ελληνικά βενζόλιο
English English benzene
French français benzène
Croatian hrvatski benzen
Italian italiano benzene
Latvian latviešu benzols
Lithuanian lietuvių benzenas
Hungarian magyar benzol
Maltese Malti benżen
Dutch Nederlands benzeen
Polish polski benzen
Portuguese português benzeno
Romanian română benzen
Slovak slovenčina benzén
Slovenian slovenščina benzen
Finnish suomi bentseeni
Swedish svenska bensen

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Benzene GHS label elements

Everything CLP Annex VI fixes for Benzene, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS08 Health hazard pictogramGHS07 Exclamation mark pictogram

Danger

Benzene

  • Highly flammable liquid and vapour.
  • May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • May cause genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • May be fatal if swallowed and enters airways.
  • Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Causes skin irritation.
  • Causes serious eye irritation.
  • Obtain special instructions before use.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Wash thoroughly after handling.
  • Do not eat, drink or smoke when using this product.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF ON SKIN:
  • IF IN EYES:
  • IF exposed or concerned:
  • Get medical advice/attention.
  • Get medical advice/attention if you feel unwell.
  • If skin irritation occurs:
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Wash with plenty of water/
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Benzene in the GHS label constructor →

07 · Health hazards

Benzene health hazards and exposure limits

Benzene hazard summary

Benzene is a colorless liquid with a sweet odor. It evaporates into the air very quickly and dissolves slightly in water. It is highly flammable and is formed from both natural processes and human activities. Benzene is widely used in the United States; it ranks in the top 20 chemicals for production volume. Some industries use benzene to make other chemicals which are used to make plastics, resins, and nylon and synthetic fibers. Benzene is also used to make some types of rubbers, lubricants, dyes, detergents, drugs, and pesticides. Natural sources of benzene include volcanoes and forest fires. Benzene is also a natural part of crude oil, gasoline, and cigarette smoke.

Source: Agency for Toxic Substances and Disease Registry (ATSDR)

Benzene carcinogenicity classification

IARC classification Group 1 — Carcinogenic to humans
IARC monographs Volume 29: (1982) Some Industrial Chemicals and Dyestuffs; Volume 120: (2018) Benzene

Under the conditions of these 2-year gavage studies, there was clear evidence of carcinogenicity of benzene for male F344/N rats, for female F344/N rats, for male B6C3F1 mice, and for female B6C3F1 mice. For male rats, benzene caused increased incidences of Zymbal gland carcinomas, squamous cell papillomas and squamous cell carcinomas of the oral cavity, and squamous cell papillomas and squamous cell carcinomas of the skin. For female rats, benzene caused increased incidences of Zymbal gland carcinomas and squamous cell papillomas and squamous cell carcinomas of the oral cavity. For male mice, benzene caused increased incidences of Zymbal gland squamous cell carcinomas, malignant lymphomas, alveolar/bronchiolar carcinomas and alveolar/bronchiolar adenomas or carcinomas (combined), harderian gland adenomas, and squamous cell carcinomas of the preputial gland. For female mice, benzene caused increased incidences of malignant lymphomas, ovarian granulosa cell tumors, ovarian benign mixed tumors, carcinomas and carcinosarcomas of the mammary gland, alveolar/bronchiolar adenomas, alveolar/bronchiolar carcinomas, and Zymbal gland squamous cell carcinomas. Dose-related lymphocytopenia was observed for male and female F344/N rats and male and female B6C3F1 mice.

Source: US National Toxicology Program · TR-289: Toxicology and Carcinogenesis Studies of Benzene (CASRN 71-43-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies) (1986 )

Classification of carcinogenicity: 1) evidence in humans: sufficient; 2) evidence in animals: sufficient; Overall summary evaluation of carcinogenic risk to humans is group 1: The chemical is carcinogenic to humans. /From table/

Source: Hazardous Substances Data Bank (HSDB)

Cancer Classification: Carcinogenic to Humans

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

Benzene occupational exposure limits

US occupational exposure limits reported for Benzene. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 1.0 [ppm], STEL(OSHA) = 5 ppm (see CFR 1910.1028) Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
PEL 1 ppm Occupational Safety and Health Administration (OSHA)
PEL 5 ppm Occupational Safety and Health Administration (OSHA)
REL 0.1 ppm Occupational Safety and Health Administration (OSHA)
REL 1 ppm Occupational Safety and Health Administration (OSHA)
REL Ca TWA 0.1 ppm ST 1 ppm See Appendix A The National Institute for Occupational Safety and Health (NIOSH)
IDLH 500 ppm ; A potential occupational carcinogen. (NIOSH, 2024) CAMEO Chemicals
IDLH 500.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
IDLH NIOSH usually recommends that occupational exposures to carcinogens be limited to the lowest feasible concentration. Hazardous Substances Data Bank (HSDB)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Benzene properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Benzene boiling point

Property Value Conditions Source
Boiling point 80.08 °C (176.1 °F) HSDB
80 °C (176 °F) NIOSH
80.11 °C (176.2 °F) at 760 mmHg CAMEO

Benzene melting point

Property Value Conditions Source
Melting point 5.56 °C (42 °F) HSDB
5.5 °C (41.9 °F) CAMEO

Benzene density

Property Value Conditions Source
Density 0.88 g/cm³ NIOSH
0.8756 g/cm³ at 20 °C HSDB
0.879 g/cm³ at 20 °C CAMEO

Benzene solubility

Property Value Conditions Source
Solubility Miscible with alcohol, chloroform, ether, carbon disulfide, acetone, oils, carbon tetrachloride, and glacial acetic acid HSDB
Miscible with ethanol, ethyl ether, acetone, chloroform; coluble in carbon tetrachloride HSDB
In water, 1.79X10+3 mg/L at 25 °C at 25 °C HSDB

Benzene vapor pressure

Property Value Conditions Source
Vapor pressure 75 mmHg NIOSH
75.0062 mmHg at 20 °C ICSC
94.8 mmHg at 25 °C HSDB

Benzene flash point

Property Value Conditions Source
Flash point -11.11 °C (12 °F) HSDB
-11 °C (12.2 °F) HSDB

Benzene autoignition temperature

Property Value Conditions Source
Autoignition temperature 497.78 °C (928 °F) HSDB
591.67 °C (1097 °F) CAMEO
498 °C (928.4 °F) ICSC

Benzene lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 1.2 % by volume HSDB
1.4 % by volume HSDB

Benzene upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 7.8 % by volume HSDB
8 % by volume HSDB

Benzene vapor density

Property Value Conditions Source
Vapor density 2.8 (air = 1) HSDB
2.77 (air = 1) CAMEO
2.7 (air = 1) ICSC

Benzene odor threshold

Property Value Conditions Source
Odor threshold 4.68 PPM HSDB
In air: 4.9 mg/cu m (characteristic odor), in water: 2.0 mg/l. HSDB
distinct odor: 310 mg/cu m= 90 ppm HSDB

Benzene critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 288.85 °C (551.9 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Benzene fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Benzene fire potential

A dangerous fire hazard when exosed to heat or flame. ... Ignites on contact with sodium peroxide + water, dioxygenyl tetrafluoroborate, iodine heptafluoride, and dioxygen difluoride.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Benzene storage and handling

Benzene reactive group

CAMEO Chemicals places Benzene in the reactive group Hydrocarbons, Aromatic. Compatibility with other chemicals is worked out from the group, not from the individual substance — which is why two substances you have never seen react can still be flagged as a pair that must be separated.

A reactive group is a CAMEO Chemicals (US NOAA) grouping, not a GHS hazard class: it has no code, no category and no legal force. It is what the storage compatibility matrix on this site computes from.

Benzene safe storage

Fireproof. Separated from food and feedstuffs, oxidants and halogens. Store in an area without drain or sewer access.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Benzene storage conditions

Keep in well closed containers in a cool place and away from fire.

Source: Hazardous Substances Data Bank (HSDB)

Benzene incompatible materials

Reacts violently with iodine pentafluoride.

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check Benzene in the storage compatibility matrix →

11 · Transport

Benzene UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Benzene under UN 1114 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
BENZENE 3 F1 II
  • ADR label model 3 — Flammable liquid
3

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 3 is “Flammable liquids” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Benzene 3 II
  • US DOT FLAMMABLE LIQUID label (§172.419)
3

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 3 is “Flammable and combustible liquid” (49 CFR 173.2).

Full UN 1114 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

Benzene — frequently asked questions

What is the CAS number of Benzene?

The CAS number of Benzene is 71-43-2. Its EC number is 200-753-7.

What is the chemical formula of Benzene?

The molecular formula of Benzene is C6H6 and its molecular weight is 78.11 g/mol.

What does a Benzene label have to show?

Under CLP Annex VI the label for Benzene carries the pictograms Flame, Health hazard and Exclamation mark and the signal word is Danger.

Is Benzene flammable?

Yes. CLP Annex VI assigns Benzene H225 — highly flammable liquid and vapour. The flash point reported for it is -11.11 °C (12 °F) (HSDB).

Is Benzene a carcinogen?

Yes. CLP Annex VI classifies Benzene as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 1: carcinogenic to humans.

What is the exposure limit for Benzene?

The US occupational exposure limit reported for Benzene is 1.0 [ppm], STEL(OSHA) = 5 ppm (see CFR 1910.1028) (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Benzene?

The boiling point reported for Benzene is 80.08 °C (176.1 °F) (HSDB).

What is the melting point of Benzene?

The melting point reported for Benzene is 5.56 °C (42 °F) (HSDB).

How should Benzene be stored?

CLP Annex VI assigns Benzene the storage statement P403. Keep in well closed containers in a cool place and away from fire. (Hazardous Substances Data Bank (HSDB))

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