Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Bis(4-hydroxy-N-methylanilinium) sulphate

Bis(4-hydroxy-N-methylanilinium) sulphate: p-methylaminophenol sulfate is an off-white crystalline solid.

CAS 55-55-0 C14H20N2O6S 344.39 g/mol Warning

01 · Identification

What Bis(4-hydroxy-N-methylaniliniu… is

Bis(4-hydroxy-N-methylanilinium) sulphate: p-methylaminophenol sulfate is an off-white crystalline solid. Its molecular formula is C14H20N2O6S and its molecular weight is 344.39 g/mol. It melts at 255 °C, is soluble in water.

Under the GHS it carries the signal word Warning.

02 · Identifiers

Bis(4-hydroxy-N-methylaniliniu… identifiers and molecular data

Bis(4-hydroxy-N-methylaniliniu… CAS number and EC number

CAS number55-55-0
EC number200-237-1
Index number (CLP Annex VI)650-031-00-4

Bis(4-hydroxy-N-methylaniliniu… molecular formula and molecular weight

Molecular formulaC14H20N2O6S
Molecular weight344.39 g/mol

03 · GHS classification

Bis(4-hydroxy-N-methylaniliniu… hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Bis(4-hydroxy-N-methylaniliniu… pictograms and signal word

Signal wordWarning

Bis(4-hydroxy-N-methylaniliniu… hazard class and category

GHS hazard classes Bis(4-hydroxy-N-methylanil… falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Skin sensitisation GHS chapter 3.4 Category 1 or 1A or 1B H317 GHS07
Specific target organ toxicity - repeated exposure GHS chapter 3.9 Category 2 H373 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Bis(4-hydroxy-N-methylaniliniu… hazard statements (H-codes)

Hazard statements assigned to Bis(4-hydroxy-N-methylanil…
CodeHazard statement
H302 Harmful if swallowed.
H373 May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H317 May cause an allergic skin reaction.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Bis(4-hydroxy-N-methylanil…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Bis(4-hydroxy-N-methylanil…

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Bis(4-hydroxy-N-methyl… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Bis(4-hydroxy-N-methylaniliniu… precautionary statements

CLP Annex VI assigns 14 precautionary statements to Bis(4-hydroxy-N-methylanil…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Bis(4-hydroxy-N-methylaniliniu… name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български бис( N -метил-4-хидроксианилиниев) сулфат
Spanish español Sulfato de bis(4-hidroxi- N -metilanilinio)
Czech čeština bis(4-hydroxy- N -methylanilinium)-sulfát
Danish dansk bis(4-hydroxy-N-methylanilinium)sulfat
German Deutsch Bis(4-hydroxy- N -methylanilinium)sulfat Metol
Estonian eesti bis(4-hüdroksü- N -metüülaniliinium)sulfaat
Greek ελληνικά θειικό δις(4-υδροξυ-N-μεθυλανιλίνιο)
English English bis(4-hydroxy-N-methylanilinium) sulphate
French français Sulfate de bis(4-hydroxy-N-méthylanilinium)
Croatian hrvatski bis(4-hidroksi- N -metilanilin)-sulfat
Italian italiano solfato di bis(4-idrossi-N-metilanilinio)
Latvian latviešu bis(4-hidroksi- N -metilanilīnija) sulfāts
Lithuanian lietuvių bi(4-hidroksi-N-metilanilinio) sulfatas
Hungarian magyar bisz(4-hidroxi- N -metilanilínium)-szulfát
Maltese Malti sulfat ta’ bis(4-idrossi-N-metilanilinju)
Dutch Nederlands bis(4-hydroxy- N -methylanilinium)sulfaat
Polish polski Siarczan(VI) bis(4-hydroksy-N-metyloanilinium)
Portuguese português sulfato de bis(4-hidroxi- N -metilanilínio)
Romanian română sulfat de bis(4-hidroxi-N-metilanilină)
Slovak slovenčina bis(4-hydroxy-N-metylanilínium)-sulfát
Slovenian slovenščina bis(4-hidroksi-N-metilanilinijev) sulfat
Finnish suomi bis(4-hydroksi-N-metyylianilinium)sulfaatti
Swedish svenska bis(4-hydroxi- N -metylanilinium)sulfat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Bis(4-hydroxy-N-methylaniliniu… GHS label elements

Everything CLP Annex VI fixes for Bis(4-hydroxy-N-methylanil…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS07 Exclamation mark pictogramGHS09 Environment pictogram

Warning

Bis(4-hydroxy-N-methylaniliniu…

  • Harmful if swallowed.
  • May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • May cause an allergic skin reaction.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Avoid breathing dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Contaminated work clothing should not be allowed out of the workplace.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Get medical advice/attention.
  • Get medical advice/attention if you feel unwell.
  • Rinse mouth.
  • If skin irritation or rash occurs:
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Bis(4-hydroxy-N-methylanil… in the GHS label constructor →

07 · Health hazards

Bis(4-hydroxy-N-methylaniliniu… health hazards and exposure limits

Bis(4-hydroxy-N-methylaniliniu… hazard summary

Allergic contact dermatitis in photographers; [Marks] An eye, respiratory tract, and mild skin irritant; A skin sensitizer; May have effects on the blood; [ICSC] Toxic by ingestion: nausea, weakness, cyanosis, vertigo, headache, and convulsions; [CAMEO] Causes somnolence, tremor, and changes in urine composition in oral lethal-dose studies of mice; Causes acute tubular necrosis and increased spleen weights in repeated, oral-dose studies of rats; [RTECS] 3% solution is not irritating to skin and mildly irritating to eyes; [EC] See N-Methyl-4-aminophenol.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

Bis(4-hydroxy-N-methylaniliniu… properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Bis(4-hydroxy-N-methylaniliniu… melting point

Property Value Conditions Source
Melting point 255 °C (491 °F) range, midpoint shown CAMEO

Bis(4-hydroxy-N-methylaniliniu… solubility

Property Value Conditions Source
Solubility Soluble (>=10 mg/ml at 68 °F) (NTP, 1992) at 20 °C CAMEO
Solubility in water, g/100ml at 15 °C: 4.7 at 15 °C ICSC

Bis(4-hydroxy-N-methylaniliniu… autoignition temperature

Property Value Conditions Source
Autoignition temperature 531 °C (987.8 °F) ICSC

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Bis(4-hydroxy-N-methylaniliniu… storage and handling

Bis(4-hydroxy-N-methylaniliniu… safe storage

Separated from incompatible materials. See Chemical Dangers.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Bis(4-hydroxy-N-methylaniliniu… reactivity

In aqueous solution behaves as an acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Bis(4-hydroxy-N-methylani… in the storage compatibility matrix →

10 · Questions

Bis(4-hydroxy-N-methylaniliniu… — frequently asked questions

What is the CAS number of Bis(4-hydroxy-N-methylaniliniu…?

The CAS number of Bis(4-hydroxy-N-methylaniliniu… is 55-55-0. Its EC number is 200-237-1.

What is the chemical formula of Bis(4-hydroxy-N-methylaniliniu…?

The molecular formula of Bis(4-hydroxy-N-methylaniliniu… is C14H20N2O6S and its molecular weight is 344.39 g/mol.

What does a Bis(4-hydroxy-N-methylaniliniu… label have to show?

Under CLP Annex VI the label for Bis(4-hydroxy-N-methylaniliniu… carries the pictograms Health hazard, Exclamation mark and Environment and the signal word is Warning.

Is Bis(4-hydroxy-N-methylaniliniu… flammable?

CLP Annex VI assigns Bis(4-hydroxy-N-methylaniliniu… no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Bis(4-hydroxy-N-methylaniliniu… a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Bis(4-hydroxy-N-methylaniliniu…. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the melting point of Bis(4-hydroxy-N-methylaniliniu…?

The melting point reported for Bis(4-hydroxy-N-methylaniliniu… is 255 °C (491 °F), range, midpoint shown (CAMEO).

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