Substance profile
Bromadiolone
Bromadiolone is a white to off-white powder and is odorless.
01 · Identification
What Bromadiolone is
Bromadiolone is a white to off-white powder and is odorless. It melts at 199 °C, is soluble in water.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Bromadiolone identifiers and molecular data
Bromadiolone CAS number and EC number
Other names for Bromadiolone
- bromadiolone (ISO)
- 3-[3-(4′-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2H-chromen-2-one
03 · GHS classification
Bromadiolone hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Bromadiolone pictograms and signal word
Bromadiolone hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 1 or 2 | H310 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 1 or 2 | H330 | GHS06 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 1 | H372 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Bromadiolone hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H360D | May damage the unborn child. |
| H330 | Fatal if inhaled. |
| H310 | Fatal in contact with skin. |
| H300 | Fatal if swallowed. |
| H372 | Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Bromadiolone. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Bromadiolone
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Bromadiolone issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Bromadiolone precautionary statements
CLP Annex VI assigns 14 precautionary statements to Bromadiolone. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Bromadiolone name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | бромадиолон (ISO) 3-[3-(4′-бромобифенил-4-ил)-1-фенил-3-хидроксипропил)-4-хидрокси-2 H -хромен-2-он |
| Spanish español | bromadiolona (ISO) 3-[3-(4′-bromobifenil-4-il)-3-hidroxi-1-fenilpropil]-4-hidroxi-2 H -cromen-2-ona |
| Czech čeština | bromadiolon (ISO) 3-[3-(4′-brombifenyl-4-yl)-3-hydroxy-1-fenylpropyl]-4-hydroxy-2 H -chromen-2-on |
| Danish dansk | bromadiolon (ISO) 3-[3-(4′-brombiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2 H -chromen-2-on |
| German Deutsch | Bromadiolon (ISO) 3-[3-(4′-Brombiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2 H -chromen-2-on |
| Estonian eesti | bromadioloon (ISO) 3-[3-(4′-bromobifenüül-4-üül)-3-hüdroksü-1-fenüülpropüül]-4-hüdroksü-2 H -kromeen-2-oon |
| Greek ελληνικά | βρωμαδιολόνη (ISO) 3-[3-(4′-βρωμοδιφαινυλ-4-υλο)-3-υδροξυ-1-φαινυλοπροπυλο]-4-υδροξυ-2 H -χρωμενόνη-2 |
| English English | bromadiolone (ISO) 3-[3-(4′-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2 H -chromen-2-one |
| French français | bromadiolone (ISO) 3-[3-(4′-bromobiphényl-4-yl)-3-hydroxy-1-phénylpropyl]-4-hydroxy-2 H -chromén-2-one |
| Croatian hrvatski | bromadiolon (ISO) 3-[3-(4′-bromobifenil-4-il)-3-hidroksi-1-fenilpropil]-4-hidroksi-2 H -kromen-2-on |
| Italian italiano | bromadiolone (ISO) 3-[3--(4′-bromobifenil-4-il)-3-idrossi-1-fenilpropil]-4-idrossi-2H-cromen-2-one |
| Latvian latviešu | bromadiolons ( ISO ) 3-[3-(4′-brombifenil-4-il)-3-hidroksi-1-fenilpropil]-4-hidroksi-2 H -hromēn-2-ons |
| Lithuanian lietuvių | bromadiolonas (ISO) 3-[3-(4′-brombifenil-4-il)-3-hidroksi-1-fenilpropil]-4-hidroksi-2 H -chromen-2-onas |
| Hungarian magyar | bromadiolon (ISO) 3-[3-(4′-bromobifenil-4-il)-3-hidroxi-1-fenilpropil]-4-hidroxi-2 H -kromén-2-on |
| Maltese Malti | bromadijolon (ISO) 3-[3-(4′-bromobifenil-4-il)-3-idrossi-1-fenilpropil]-4-idrossi-2 H -kromen-2-on |
| Dutch Nederlands | bromadiolon (ISO) 3-[3-(4′ -broombifenyl-4-yl)-3-hydroxy-1-fenylpropyl]-4-hydroxy-2 H -chromeen-2-on |
| Polish polski | bromadiolon (ISO) 3-[3-(4′-bromobifenylo-4-ylo)-3-hydroksy-1-fenylopropylo]-4-hydroksy-2 H -chromen-2-on |
| Portuguese português | bromadiolona (ISO) 3-[3-(4′-bromobifenil-4-il)-3-hidroxi-1-fenilpropil]-4-hidroxi-2 H -cromen-2-ona |
| Romanian română | bromadiolonă (ISO) 3-[3-(4′-bromobifenil-4-il)-3-hidroxi-1-fenilpropil]-4-hidroxi-2 H -cromen-2-onă |
| Slovak slovenčina | bromadiolón (ISO) 3-[3-(4′-bróm[1,1′-bifenyl]-4-yl)-1-fenyl-3-hydroxypropyl]-4-hydroxybenzopyrán-2-ón |
| Slovenian slovenščina | bromadiolon (ISO) 3-[3-(4′-bromobifenil-4-il)-3-hidroksi-1-fenilpropil]-4-hidroksi-2 H -kromen-2-on |
| Finnish suomi | bromadioloni (ISO) 3-[3-(4′-bromibifenyl-4-yyli)-3-hydroksi-1-fenyylipropyyli]-4-hydroksi-2 H -kromen-2-oni |
| Swedish svenska | bromadiolon (ISO) 3-[3-(4′-brombifenyl-4-yl)-3-hydroxi-1-fenylpropyl]-4-hydroxi-2 H -kromen-2-on |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Bromadiolone GHS label elements
Everything CLP Annex VI fixes for Bromadiolone, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Bromadiolone
- May damage the unborn child.
- Fatal if inhaled.
- Fatal in contact with skin.
- Fatal if swallowed.
- Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Bromadiolone in the GHS label constructor →
07 · Health hazards
Bromadiolone health hazards and exposure limits
Bromadiolone hazard summary
A vitamin K antagonist; The only significant adverse effect observed in 90 day oral rat studies was reduction in prothrombin time; No evidence of developmental toxicity or teratogenicity in rats and rabbits; [HSDB] Biphasic liver elimination which is initially rapid at 2-8 days followed by a slow phase with a 170 day half life; Not irritating to skin and mildly irritating to eyes; No evidence of teratogenicity or mutagenicity; [INCHEM PDS: Bromadiolone - 1996] No information on reproductive or lactation effects; [REPROTOX] See Warfarin.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Bromadiolone properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Bromadiolone boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | Decomposes, without boiling, above the melting point | decomposes | HSDB |
Bromadiolone melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 199.05 °C (390.3 °F) | range, midpoint shown | HSDB |
| 205 °C (401 °F) | range, midpoint shown | CAMEO |
Bromadiolone density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.45 g/cm³ | at 20.5 °C | HSDB |
Bromadiolone solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Soluble in dimethylsulfoxide | HSDB | |
| Solubility at 20-25 °C (g/L): dimethylformamide 730.0; ethyl acetate 25.0; acetone 22.3; chloroform 10.1; ethanol 8.2; methanol 5.6; ethyl ether 3.7; hexane 0.2 | HSDB | ||
| In water, >1.14X10+4 at pH 5, 2.48X10-3 at pH 7, 0.180 at pH 9 (all in g/L at 20 °C) | at 20 °C | HSDB |
Bromadiolone vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 1.598e-10 mmHg | at 25 °C | HSDB |
| 3.75e-7 mmHg | at 45 °C | HSDB | |
| 2e-8 mmHg | Haz-Map |
Bromadiolone flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 218 °C (424.4 °F) | HSDB |
Bromadiolone corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | Non-corrosive | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Bromadiolone storage and handling
Bromadiolone storage conditions
Keep container tightly closed in a dry and well-ventilated place.
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check Bromadiolone in the storage compatibility matrix →
10 · Questions
Bromadiolone — frequently asked questions
What is the CAS number of Bromadiolone?
The CAS number of Bromadiolone is 28772-56-7. Its EC number is 249-205-9.
What does a Bromadiolone label have to show?
Under CLP Annex VI the label for Bromadiolone carries the pictograms Health hazard, Skull and crossbones and Environment and the signal word is Danger.
Is Bromadiolone flammable?
CLP Annex VI assigns Bromadiolone no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 218 °C (424.4 °F) (HSDB).
Is Bromadiolone a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Bromadiolone. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Bromadiolone?
The boiling point reported for Bromadiolone is Decomposes, without boiling, above the melting point, decomposes (HSDB).
What is the melting point of Bromadiolone?
The melting point reported for Bromadiolone is 199.05 °C (390.3 °F), range, midpoint shown (HSDB).
How should Bromadiolone be stored?
Keep container tightly closed in a dry and well-ventilated place. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Bromadiolone
Keep going: substances starting with B, or search the whole database by name, CAS number, pictogram or signal word.