Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Bromoxynil

Bromoxynil is a white crystalline solid and is odorless.

CAS 1689-84-5 C7H3Br2NO 276.91 g/mol Danger

01 · Identification

What Bromoxynil is

Bromoxynil is a white crystalline solid and is odorless. Its molecular formula is C7H3Br2NO and its molecular weight is 276.91 g/mol. It melts at 190 °C.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Bromoxynil identifiers and molecular data

Bromoxynil CAS number and EC number

CAS number1689-84-5
EC number216-882-7
Index number (CLP Annex VI)608-006-00-0

Bromoxynil molecular formula and molecular weight

Molecular formulaC7H3Br2NO
Molecular weight276.91 g/mol

Other names for Bromoxynil

  • bromoxynil (ISO)
  • 3,5-dibromo-4-hydroxybenzonitrile
  • bromoxynil phenol

03 · GHS classification

Bromoxynil hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Bromoxynil pictograms and signal word

Signal wordDanger

Bromoxynil hazard class and category

GHS hazard classes Bromoxynil falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - inhalation GHS chapter 3.1 Category 1 or 2 H330 GHS06
Skin sensitisation GHS chapter 3.4 Category 1 or 1A or 1B H317 GHS07
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Bromoxynil hazard statements (H-codes)

Hazard statements assigned to Bromoxynil
CodeHazard statement
H361d Suspected of damaging the unborn child.
H330 Fatal if inhaled.
H301 Toxic if swallowed.
H317 May cause an allergic skin reaction.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Bromoxynil. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Bromoxynil

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Bromoxynil issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Bromoxynil precautionary statements

CLP Annex VI assigns 15 precautionary statements to Bromoxynil. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Bromoxynil name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български бромоксинил (ISO) 3,5-дибромо-4-хидроксибензонитрилбромоксинил фенол
Spanish español Bromoxinilo (ISO) 3,5-dibromo-4-hidroxibenzonitrilobromoxinil-fenol
Czech čeština bromoxynil (ISO) 3,5-dibrom-4-hydroxybenzonitrilbromoxynilfenol
Danish dansk bromoxynil (ISO), 3,5-dibrom-4-hydroxybenzonitril bromoxynil-phenol
German Deutsch Bromoxynil (ISO) 3,5-Dibrom-4-hydroxybenzonitril
Estonian eesti bromoksüniil (ISO) 3,5-dibromo-4-hüdroksübensonitriilbromoksüniilfenool
Greek ελληνικά bromoxynil (βρωμοξυνίλη) (ISO) 3,5-διβρωμο-4-υδροξυβενζονιτρίλιοφαινολική βρωμοξυνίλη
English English bromoxynil (ISO) 3,5-dibromo-4-hydroxybenzonitrile bromoxynil phenol
French français bromoxynil (ISO) 3,5-dibromo-4-hydroxybenzonitrilebromoxynil phénol
Croatian hrvatski bromoksinil (ISO) 3,5-dibrom-4-hidroksibenzonitrilbromoksinil-fenol
Italian italiano bromoxinil (ISO) 3,5-dibromo-4-idrossibenzonitrile
Latvian latviešu bromoksinils (ISO) 3,5-dibrom-4-hidroksibenzonitrilsbromoksinilfenols
Lithuanian lietuvių bromoksinilas (ISO) 3,5-dibrom-4-hidroksibenznitrilas bromoksinilo fenolis
Hungarian magyar bromoxinil (ISO) 3,5-dibróm-4-hidroxibenzonitrilbromoxinilfenol
Maltese Malti bromossinil (ISO) 3,5-dibromo-4-idrossibenżonitril fenol tal-bromossinil
Dutch Nederlands bromoxynil (ISO) 3,5-dibroom-4-hydroxybenzonitrilbromoxynil-fenol
Polish polski bromoksynil (ISO) 3,5-dibromo-4-hydroksybenzonitrylfenol bromoksynilu
Portuguese português bromoxinil (ISO) 3,5-dibromo-4-hidroxibenzonitrilobromoxinil-fenol
Romanian română bromoxinil(ISO) 3,5-dibromo-4-hidroxibenzonitrilbromoxinil fenol
Slovak slovenčina bromoxynil (ISO) 3,5-dibróm-4-hydroxybenzonitril
Slovenian slovenščina bromoksinil (ISO) 3,5-dibromo-4-hidroksibenzonitrilbromoksinil fenol
Finnish suomi bromoksiniili (ISO) 3,5-dibromi-4-hydroksibentsonitriilibromoksiliinifenoli
Swedish svenska bromoxinil (ISO) 3,5-dibrom-4-hydroxibensonitrilbromoxinilfenol

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Bromoxynil GHS label elements

Everything CLP Annex VI fixes for Bromoxynil, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS08 Health hazard pictogramGHS09 Environment pictogram

Danger

Bromoxynil

  • Suspected of damaging the unborn child.
  • Fatal if inhaled.
  • Toxic if swallowed.
  • May cause an allergic skin reaction.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Avoid breathing dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Contaminated work clothing should not be allowed out of the workplace.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF INHALED:
  • Immediately call a POISON CENTER/doctor/
  • Get medical advice/attention.
  • Rinse mouth.
  • If skin irritation or rash occurs:
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Bromoxynil in the GHS label constructor →

07 · Health hazards

Bromoxynil health hazards and exposure limits

Bromoxynil hazard summary

Mildly irritating to eyes and abraded skin of rabbits; No significant adverse effects were observed in a three month high-dose feeding study with rats; Dermal and inhalation studies with 10% solution had the same outcome; Four workers in a manufacturing plant making both bromoxynil and ioxynil developed typical symptoms of uncoupler poisoning including excessive perspiration, thirst, fever, emesis, myalgia, and weight loss. ... The effects reversed rapidly after exposure ceased. [HSDB] May cause skin sensitization; [eChemPortal: ESIS] An irritant; May cause skin sensitization; [MSDSonline] Effects in high-dose animal studies include changes in structure or function of salivary glands, zonal hepatitis (hepatocellular necrosis), and other changes to liver; [RTECS] At maternally toxic doses in rodents, supernumerary ribs and reduced fetal weights were observed; No human pregnancy effects are known; [REPROTOX] See Benzonitrile.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Bromoxynil carcinogenicity classification

Cancer Classification: Group C Possible Human Carcinogen

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

Bromoxynil occupational exposure limits

US occupational exposure limits reported for Bromoxynil. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 5.0 [mg/m3], as CN Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Bromoxynil properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Bromoxynil melting point

Property Value Conditions Source
Melting point 190 °C (374 °F) range, midpoint shown HSDB
194.5 °C (382.1 °F) range, midpoint shown, at 0.15 mmHg (reduced pressure) HSDB

Bromoxynil solubility

Property Value Conditions Source
Solubility IN WATER 130 PPM (0.013%) WT/VOL @ 20-25 °C; IN ETHANOL 7% WT/VOL @ 20-25 °C; IN LIGHT PETROLEUM & XYLENE 1-2% WT/VOL @ 20-25 °C HSDB
IN DIMETHYLFORMAMIDE 61% WT/VOL @ 20-25 °C; IN BENZENE 1% WT/VOL @ 20-25 °C; IN METHANOL 9% WT/VOL @ 20-25 °C; IN ACETONE 17% WT/VOL AT 20-25 °C HSDB
Solubility in (g/L) at 25 °C: acetone 170; tetrahydrofuran 410 at 25 °C HSDB

Bromoxynil vapor pressure

Property Value Conditions Source
Vapor pressure 1275 mmHg at 25 °C HSDB
5e-8 mmHg Haz-Map

Bromoxynil corrosivity

Property Value Conditions Source
Corrosivity Non-corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Bromoxynil storage and handling

Bromoxynil storage conditions

Store at temperatures above 3 °F. If allowed to freeze, remix before using. Do not contaminate water, food, or feed by storage ... of this chemical.

Source: Hazardous Substances Data Bank (HSDB)

Bromoxynil reactivity

BROMOXYNIL is a weak acid.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Bromoxynil in the storage compatibility matrix →

10 · Questions

Bromoxynil — frequently asked questions

What is the CAS number of Bromoxynil?

The CAS number of Bromoxynil is 1689-84-5. Its EC number is 216-882-7.

What is the chemical formula of Bromoxynil?

The molecular formula of Bromoxynil is C7H3Br2NO and its molecular weight is 276.91 g/mol.

What does a Bromoxynil label have to show?

Under CLP Annex VI the label for Bromoxynil carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.

Is Bromoxynil flammable?

CLP Annex VI assigns Bromoxynil no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Bromoxynil a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Bromoxynil. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Bromoxynil?

The US occupational exposure limit reported for Bromoxynil is 5.0 [mg/m3], as CN (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the melting point of Bromoxynil?

The melting point reported for Bromoxynil is 190 °C (374 °F), range, midpoint shown (HSDB).

How should Bromoxynil be stored?

Store at temperatures above 3 °F. If allowed to freeze, remix before using. Do not contaminate water, food, or feed by storage ... of this chemical. (Hazardous Substances Data Bank (HSDB))

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