Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Carboxin

Carboxin is crystals from ethanol or methanol.

CAS 5234-68-4 C12H13NO2S 235.3 g/mol Warning

01 · Identification

What Carboxin is

Carboxin is crystals from ethanol or methanol. Its molecular formula is C12H13NO2S and its molecular weight is 235.3 g/mol. It melts at 92 °C.

Under the GHS it carries the signal word Warning.

02 · Identifiers

Carboxin identifiers and molecular data

Carboxin CAS number and EC number

CAS number5234-68-4
EC number226-031-1
Index number (CLP Annex VI)616-226-00-3

Carboxin molecular formula and molecular weight

Molecular formulaC12H13NO2S
Molecular weight235.3 g/mol

Other names for Carboxin

  • carboxin (ISO)
  • 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide
  • 5,6-dihydro-2-methyl-1,4-oxathiine-3-carboxanilide

03 · GHS classification

Carboxin hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Carboxin pictograms and signal word

Signal wordWarning

Carboxin hazard class and category

GHS hazard classes Carboxin falls into
Hazard class Category From code Pictogram
Skin sensitisation GHS chapter 3.4 Category 1 or 1A or 1B H317 GHS07
Specific target organ toxicity - repeated exposure GHS chapter 3.9 Category 2 H373 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Carboxin hazard statements (H-codes)

Hazard statements assigned to Carboxin
CodeHazard statement
H373 May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H317 May cause an allergic skin reaction.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Carboxin. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Carboxin

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Carboxin issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Carboxin precautionary statements

CLP Annex VI assigns 11 precautionary statements to Carboxin. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Carboxin name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български карбоксин (ISO) 2-метил-N-фенил-5,6-дихидро-1,4-оксатиин-3-карбоксамид5,6-дихидро-2-метил-1,4-оксатиин-3-карбоксанилид
Spanish español Carboxina (ISO) 2-metil-N-fenil-5,6-dihidro-1,4-oxatiina-3-carboxamida5,6-dihidro-2-metil-1,4-oxatiin-3-carboxanilida
Czech čeština karboxin (ISO) 2-methyl- N -fenyl-5,6-dihydro-1,4-oxathiin-3-karboxamid5,6-dihydro-2-methyl-1,4-oxathiin-3-karboxanilid
Danish dansk carboxin (ISO) 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiin-3-carboxamid5,6-dihydro-2-methyl-1,4-oxathiin-3-carboxanilid
German Deutsch Carboxin (ISO) 2-Methyl- N -phenyl-5,6-dihydro-1,4-oxathiin-3-carboxamid5,6-Dihydro-2-methyl-1,4-oxathiin-3-carboxanilid
Estonian eesti karboksiin (ISO) 2-metüül- N -fenüül-5,6-dihüdro-1,4-oksatiin-3-carboksamiid5,6-dihüdro-2-metüül-1,4-oksatiin-3-karboksaniliid
Greek ελληνικά carboxin (καρβοξίνη) (ISO) 2-μεθυλο-Ν-φαινυλο-5,6-διυδρο-1,4-οξαθειινο-3-καρβοξαμίδιο5,6-διυδρο-2-μεθυλο-1,4-οξαθειινο-3-καρβοξανιλίδιο
English English carboxin (ISO) 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide5,6-dihydro-2-methyl-1,4-oxathiine-3-carboxanilide
French français carboxine (ISO) 2-méthyl-N-phényl-5,6-dihydro-1,4-oxathiine-3-carboxamide5,6-dihydro-2-méthyl-1,4-oxathiine-3-carboxanilide
Croatian hrvatski karboksin (ISO) 2-metil- N -fenil-5,6-dihidro-1,4-oksatiin-3-karboksamid5,6-dihidro-2-metil-1,4-oksatiin-3-karboksanilid
Italian italiano carbossina (ISO) 2-metil-N-fenil-5,6-diidro-1,4-ossatiina-3-carbossiammide5,6-diidro-2-metil-1,4-ossatiin-3- carbossanilida
Latvian latviešu karboksīns (ISO) 2-metil- N -fenil-5,6-dihidro-1,4-oksatiīn-3-karboksamīds5,6-dihidro-2-metil-1,4-oksatiīn-3-karboksanilīds
Lithuanian lietuvių karboksinas (ISO) 2-metil-N-fenil-5,6-dihidro-1,4-oksatiin-3-karboksamidas5,6-dihidro-2-metil-1,4-oksaatiin-3-karboksanilidas
Hungarian magyar karboxin (ISO) 2-metil-N-fenil-5,6-dihidro-1,4-oxatiin-3-karboxamid5,6-dihidro-2-metil-1,4-oxatiine-3-karboxanilid
Maltese Malti karbossin (ISO) 2-metil- N -fenil-5,6-diidro-1,4-ossatiin-3-karbossammid5,6-diidro-2-metil-1,4-ossatiin-3-karbossanilid
Dutch Nederlands carboxine (ISO) 2-methyl- N -phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide5,6-dihydro-2-methyl-1,4-oxathiin-3-carboxanilide
Polish polski karboksyna (ISO) 2-metylo-N-fenylo-5,6-dihydro-1,4-oksatiino-3-karboksamid5,6-dihydro-2-metylo-1,4-oksatiino-3-karboksyanilid
Portuguese português carboxina (ISO) 2-metil-N-fenil-5,6-di-hidro-1,4-oxatiina-3-carboxamida5,6-di-hidro-2-metil-1,4-oxatiina-3-carboxanilida
Romanian română carboxină (ISO) 2-metil-N-fenil-5,6-dihidro-1,4-oxatiin-3-carboxamidă5,6-dihidro-2-metil-1,4-oxatiin-3-carboxanilidă
Slovak slovenčina karboxín (ISO) N-fenyl-2-metyl-5,6-dihydro-1,4-oxatiín-3-karboxamid5,6-dihydro-2-metyl-1,4-oxatiín-3-karboxanilid
Slovenian slovenščina karboksin (ISO) 2-metil-N-fenil-5,6-dihidro-1,4-oksatiin-3-karboksamid5,6-dihidro-2-metil-1,4-oksatiin-3-karboksanilid
Finnish suomi Karboksiini (ISO) 2-metyyli-N-fenyyli-5,6- dihydro-1,4-oksatiini-3-karboksamidi5,6-dihydro-2-metyyli-1,4-oksatiini-3- karboksanilidi
Swedish svenska karboxin (ISO) 2-metyl-N-fenyl-5,6-dihydro-1,4-oxatiin-3-karboxamid5,6-dihydro-2-metyl-1,4-oxatiin-3-karboxanilid

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Carboxin GHS label elements

Everything CLP Annex VI fixes for Carboxin, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS07 Exclamation mark pictogramGHS08 Health hazard pictogramGHS09 Environment pictogram

Warning

Carboxin

  • May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • May cause an allergic skin reaction.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Avoid breathing dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Contaminated work clothing should not be allowed out of the workplace.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • Get medical advice/attention.
  • Get medical advice/attention if you feel unwell.
  • If skin irritation or rash occurs:
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Carboxin in the GHS label constructor →

07 · Health hazards

Carboxin health hazards and exposure limits

Carboxin hazard summary

In high-dose animal studies, causes injury to the liver and kidneys; [RTECS] May cause irritation; [MSDSonline] No significant evidence of carcinogenicity; Low acute toxicity; [ToxPlanet: EPA REDs Fact Sheets]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Carboxin carcinogenicity classification

Cancer Classification: Not Likely to be Carcinogenic to Humans

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

Carboxin properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Carboxin melting point

Property Value Conditions Source
Melting point 92 °C (197.6 °F) range, midpoint shown HSDB
91.5 °C (196.7 °F) DrugBank

Carboxin density

Property Value Conditions Source
Density 1.7 g/cm³ HSDB

Carboxin solubility

Property Value Conditions Source
Solubility 221.2 g/L in acetone, 89.33 g/L in methanol, 107.7 g/L in ethyl acetate, all at 20 °C. at 20 °C HSDB
In water, 147 mg/L at 20 °C at 20 °C HSDB
147 mg/L (at 20 °C) at 20 °C DrugBank

Carboxin vapor pressure

Property Value Conditions Source
Vapor pressure 1.5e-7 mmHg at 25 °C HSDB
1.8e-7 mmHg Haz-Map

Carboxin flash point

Property Value Conditions Source
Flash point 203 °C (397.4 °F) HSDB

Carboxin corrosivity

Property Value Conditions Source
Corrosivity Non-corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Carboxin storage and handling

Carboxin storage conditions

Store in cool, dry area out of reach of children and animals.

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check Carboxin in the storage compatibility matrix →

10 · Questions

Carboxin — frequently asked questions

What is the CAS number of Carboxin?

The CAS number of Carboxin is 5234-68-4. Its EC number is 226-031-1.

What is the chemical formula of Carboxin?

The molecular formula of Carboxin is C12H13NO2S and its molecular weight is 235.3 g/mol.

What does a Carboxin label have to show?

Under CLP Annex VI the label for Carboxin carries the pictograms Exclamation mark, Health hazard and Environment and the signal word is Warning.

Is Carboxin flammable?

CLP Annex VI assigns Carboxin no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 203 °C (397.4 °F) (HSDB).

Is Carboxin a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Carboxin. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the melting point of Carboxin?

The melting point reported for Carboxin is 92 °C (197.6 °F), range, midpoint shown (HSDB).

How should Carboxin be stored?

Store in cool, dry area out of reach of children and animals. (Hazardous Substances Data Bank (HSDB))

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