Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Chlorpropham

Chlorpropham is a colorless solid with a faint characteristic odor.

CAS 101-21-3 C10H12ClNO2 213.66 g/mol Warning

01 · Identification

What Chlorpropham is

Chlorpropham is a colorless solid with a faint characteristic odor. Its molecular formula is C10H12ClNO2 and its molecular weight is 213.66 g/mol. It boils at 246 °C, melts at 41.4 °C.

Under the GHS it carries the signal word Warning.

02 · Identifiers

Chlorpropham identifiers and molecular data

Chlorpropham CAS number and EC number

CAS number101-21-3
EC number202-925-7
Index number (CLP Annex VI)006-096-00-0

Chlorpropham molecular formula and molecular weight

Molecular formulaC10H12ClNO2
Molecular weight213.66 g/mol

Other names for Chlorpropham

  • chlorpropham (ISO)
  • isopropyl 3-chlorocarbanilate

03 · GHS classification

Chlorpropham hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Chlorpropham pictograms and signal word

Signal wordWarning

Chlorpropham hazard class and category

GHS hazard classes Chlorpropham falls into
Hazard class Category From code Pictogram
Carcinogenicity GHS chapter 3.6 Category 2 H351 GHS08
Specific target organ toxicity - repeated exposure GHS chapter 3.9 Category 2 H373 GHS08
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 2 H411 GHS09

Chlorpropham hazard statements (H-codes)

Hazard statements assigned to Chlorpropham
CodeHazard statement
H351 Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H373 May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H411 Toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Chlorpropham. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Chlorpropham

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Chlorpropham issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Chlorpropham precautionary statements

CLP Annex VI assigns 10 precautionary statements to Chlorpropham. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Chlorpropham name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български хлорпрофам (ISO) изопропилов 3-хлорокарбанилат
Spanish español Clorprofam (ISO) 3-clorocarbanilato de isopropilo
Czech čeština chlorprofam (ISO) isopropyl-3-chlorkarbanilát
Danish dansk chlorpropham (ISO) isopropyl-3-chlorcarbanilat
German Deutsch Chlorpropham (ISO) Isopropyl-3-chlorcarbanilat
Estonian eesti kloorprofaam (ISO) isopropüül-3-klorokarbanilaat
Greek ελληνικά chlorpropham (χλωρπροφάμη) (ISO) 3-χλωροκαρβανιλικός ισοπροπυλεστέρας
English English chlorpropham (ISO) isopropyl 3-chlorocarbanilate
French français chlorprophame (ISO) 3-chlorocarbanilate d'isopropyle
Croatian hrvatski klorprofam (ISO) izopropil-3-klorkarbanilat
Italian italiano clorprofam (ISO) isopropil 3-clorocarbanilato
Latvian latviešu hlorprofāms (ISO) izopropil-3-hlorkarbanilāts
Lithuanian lietuvių chlorprofamas (ISO) izopropil-3-chlorkarbanilatas
Hungarian magyar klórprofám (ISO) izopropil-3-klór-karbanilát
Maltese Malti klorprofam (ISO) 3-klorokarbanilat tal-isopropil
Dutch Nederlands chloorprofam (ISO) isopropyl-3-chloorcarbanilaat
Polish polski chloroprofam (ISO) 3-chlorokarbanilan izopropylu
Portuguese português clorprofame (ISO) 3-clorocarbanilato de isopropilo
Romanian română clorprofam (ISO) izopropil 3-clorocarbanilat
Slovak slovenčina chlórprofám (ISO) O -izopropyl-3-chlórkarbanilát
Slovenian slovenščina klorprofam (ISO) izopropil 3-klorokarbanilat
Finnish suomi klorprofaami (ISO) isopropyyli-3-kloorikarbanilaatti
Swedish svenska klorprofam (ISO) isopropyl-3-klorkarbanilat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Chlorpropham GHS label elements

Everything CLP Annex VI fixes for Chlorpropham, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS09 Environment pictogram

Warning

Chlorpropham

  • Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Toxic to aquatic life with long lasting effects.
  • Obtain special instructions before use.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF exposed or concerned:
  • Get medical advice/attention.
  • Get medical advice/attention if you feel unwell.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Chlorpropham in the GHS label constructor →

07 · Health hazards

Chlorpropham health hazards and exposure limits

Chlorpropham hazard summary

A mild skin, eye, and respiratory tract irritant; [ICSC] May cause irritation; [MSDSonline]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Chlorpropham carcinogenicity classification

IARC classification Group 3 — Not classifiable as to its carcinogenicity to humans
IARC monographs Volume 12: (1976) Some Carbamates, Thiocarbamates and Carbazides

Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans

Source: Hazardous Substances Data Bank (HSDB)

Classification of carcinogenicity: 1) evidence in humans: No adequate data. 2) evidence in animals: Inadequate data. Overall summary evaluation of carcinogenic risk to humans is Group 3: The agent is not classifiable as to its carcinogenicity to humans. /From table/

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

Chlorpropham properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Chlorpropham boiling point

Property Value Conditions Source
Boiling point 246 °C (474.8 °F) decomposes HSDB
247.22 °C (477 °F) decomposes, at 760 mmHg CAMEO
149 °C (300.2 °F) at 2 mmHg (reduced pressure) HSDB

Chlorpropham melting point

Property Value Conditions Source
Melting point 41.39 °C (106.5 °F) CAMEO
41 °C (105.8 °F) ICSC
40.9 °C (105.6 °F) range, midpoint shown HSDB

Chlorpropham density

Property Value Conditions Source
Density 1.18 g/cm³ ICSC
1.18 g/cm³ at 30 °C HSDB

Chlorpropham solubility

Property Value Conditions Source
Solubility In water, 89 mg/L at 25 °C at 25 °C HSDB

Chlorpropham vapor pressure

Property Value Conditions Source
Vapor pressure 180000 mmHg at 20 °C HSDB
2 mmHg at 149 °C HSDB
2 mmHg at 148.89 °C CAMEO

Chlorpropham corrosivity

Property Value Conditions Source
Corrosivity Non-corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Source notes

Further notes on Chlorpropham

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Solubility

Miscible in acetone, carbon disulfide; very soluble in anhydrous ammonia, aromatic solvents, ethyl and isopropyl alcohol, ketones; soluble in kerosene or diesel oil

Source: HSDB

Readily soluble in most organic solvents (e.g., alcohols, ketones, esters, chlorinated hydrocarbons, aromatic hydrocarbons); moderately soluble in mineral oils (100 g/kg kerosene)

Source: HSDB

10 · Handling and storage

Chlorpropham storage and handling

Chlorpropham safe storage

Separated from food and feedstuffs.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Chlorpropham reactivity

ISOPROPYL-N-(3-CHLOROPHENYL)CARBAMATE is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Chlorpropham in the storage compatibility matrix →

11 · Questions

Chlorpropham — frequently asked questions

What is the CAS number of Chlorpropham?

The CAS number of Chlorpropham is 101-21-3. Its EC number is 202-925-7.

What is the chemical formula of Chlorpropham?

The molecular formula of Chlorpropham is C10H12ClNO2 and its molecular weight is 213.66 g/mol.

What does a Chlorpropham label have to show?

Under CLP Annex VI the label for Chlorpropham carries the pictograms Health hazard and Environment and the signal word is Warning.

Is Chlorpropham flammable?

CLP Annex VI assigns Chlorpropham no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is Chlorpropham a carcinogen?

CLP Annex VI assigns Chlorpropham H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.

What is the boiling point of Chlorpropham?

The boiling point reported for Chlorpropham is 246 °C (474.8 °F), decomposes (HSDB).

What is the melting point of Chlorpropham?

The melting point reported for Chlorpropham is 41.39 °C (106.5 °F) (CAMEO).

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